-
公开(公告)号：US06787082B1
公开(公告)日：2004-09-07
申请号：US09890021
申请日：2001-10-10
申请人： Hikaru Fukuyama , Hiroshi Fukada , Tetsuro Tabata , Etsuji Nakamura , Norio Kameoka , Toshihiro Shimizu
发明人： Hikaru Fukuyama , Hiroshi Fukada , Tetsuro Tabata , Etsuji Nakamura , Norio Kameoka , Toshihiro Shimizu
IPC分类号： B29C4304
CPC分类号： B30B11/08 , B30B15/065
摘要： The punch coated with Cr-Dopé-N is advantageous as a punch for preparing tablets containing an acidic substance or an adhesive substance and is excellent in corrosion resistance and releasing property.
摘要翻译： 用Cr-Dopé-N涂布的冲头作为用于制备含有酸性物质或粘合物质的片剂的冲头是有利的，并且具有优异的耐腐蚀性和脱模性。
-
2.发明申请公开(公告)号：US20070116764A1
公开(公告)日：2007-05-24
申请号：US10581071
申请日：2004-11-30
CPC分类号： A61K9/282 , A61J3/007 , A61K9/2072 , B41M3/00 , B41M5/0011
摘要： The present invention provides a method for treating a solid dosage form to improve the printability and abrasion resistance of a print to be produced on a surface of the solid dosage form, which includes treating the surface of the solid dosage form with a polyethylene glycol-containing aqueous solution before printing; a production method of a solid dosage form with a printed surface, which includes printing on the surface after the aforementioned treatment; and a solid dosage form having a print improved in abrasion resistance on its surface, which can be obtained by the aforementioned production method.
摘要翻译： 本发明提供了一种治疗固体剂型以提高在固体剂型表面上产生的印刷品的印刷性和耐磨性的方法，其包括用含聚乙二醇的固体剂型表面处理固体剂型 印刷前的水溶液; 具有印刷表面的固体剂型的制造方法，其包括在上述处理后在表面上印刷; 以及通过上述制造方法得到的表面耐磨损性改善的固体剂型。
-
3.发明授权公开(公告)号：US09149437B2
公开(公告)日：2015-10-06
申请号：US12659630
申请日：2010-03-15
CPC分类号： A61K9/282 , A61J3/007 , A61K9/2072 , B41M3/00 , B41M5/0011
摘要： The present invention provides a method for treating a solid dosage form to improve the printability and abrasion resistance of a print to be produced on a surface of the solid dosage form, which includes treating the surface of the solid dosage form with a polyethylene glycol-containing aqueous solution before printing; a production method of a solid dosage form with a printed surface, which includes printing on the surface after the aforementioned treatment; and a solid dosage form having a print improved in abrasion resistance on its surface, which can be obtained by the aforementioned production method.
摘要翻译： 本发明提供了一种治疗固体剂型以提高在固体剂型表面上产生的印刷品的印刷性和耐磨性的方法，其包括用含聚乙二醇的固体剂型表面处理固体剂型 印刷前的水溶液; 具有印刷表面的固体剂型的制造方法，其包括在上述处理后在表面上印刷; 以及通过上述制造方法得到的表面耐磨损性改善的固体剂型。
-
4.发明申请公开(公告)号：US20110014130A1
公开(公告)日：2011-01-20
申请号：US12659630
申请日：2010-03-15
CPC分类号： A61K9/282 , A61J3/007 , A61K9/2072 , B41M3/00 , B41M5/0011
摘要： The present invention provides a method for treating a solid dosage form to improve the printability and abrasion resistance of a print to be produced on a surface of the solid dosage form, which includes treating the surface of the solid dosage form with a polyethylene glycol-containing aqueous solution before printing; a production method of a solid dosage form with a printed surface, which includes printing on the surface after the aforementioned treatment; and a solid dosage form having a print improved in abrasion resistance on its surface, which can be obtained by the aforementioned production method.
摘要翻译： 本发明提供了一种治疗固体剂型以提高在固体剂型表面上产生的印刷品的印刷性和耐磨性的方法，其包括用含聚乙二醇的固体剂型表面处理固体剂型 印刷前的水溶液; 具有印刷表面的固体剂型的制造方法，其包括在上述处理后在表面上印刷; 以及通过上述制造方法得到的表面耐磨损性改善的固体剂型。
-
公开(公告)号：US20140023708A1
公开(公告)日：2014-01-23
申请号：US14002451
申请日：2012-03-02
申请人： Kazuki Harada , Hikaru Fukuyama , Masahiko Koike
发明人： Kazuki Harada , Hikaru Fukuyama , Masahiko Koike
IPC分类号： A61K9/20
CPC分类号： A61K9/2095 , A61K9/2072 , A61K9/2086 , A61K9/209 , A61K45/06
摘要： According to the present invention, a multilayer tablet showing suppressed layer separation and a production method thereof are provided. A concave portion having a depth of not less than 0.1 mm Ka is formed on at least one surface Sa of the both front and back surfaces (Sa, Sb) of a multilayer tablet. Particularly, a multilayer structure obtained by, in tableting, forming a convex portion for forming the concave portion on at least the upper punch, and preliminarily compressing all layers in the multilayer tablet with the upper punch to form a concave portion having the same shape with a depth of not less than 0.1 mm on the upper surface of all layers, wherein the powder materials of the next layer are protruding into the concave portion, is a preferable embodiment.
摘要翻译： 根据本发明，提供了显示抑制层分离的多层片剂及其制备方法。 在多层片剂的前表面（Sa，Sb）的至少一个表面Sa上形成具有不小于0.1mm的深度的凹部的凹部。 特别是，通过在至少在上冲头上形成用于形成凹部的凸部的压片成型，并用上冲头预先压缩多层片剂中的所有层而形成具有相同形状的凹部而获得的多层结构， 在所有层的上表面上的深度不小于0.1mm，其中下一层的粉末材料突出到凹部中，是优选的实施方案。
-
公开(公告)号：US09326946B2
公开(公告)日：2016-05-03
申请号：US14002451
申请日：2012-03-02
申请人： Kazuki Harada , Hikaru Fukuyama , Masahiko Koike
发明人： Kazuki Harada , Hikaru Fukuyama , Masahiko Koike
CPC分类号： A61K9/2095 , A61K9/2072 , A61K9/2086 , A61K9/209 , A61K45/06
摘要： According to the present invention, a multilayer tablet showing suppressed layer separation and a production method thereof are provided. A concave portion having a depth of not less than 0.1 mm Ka is formed on at least one surface Sa of the both front and back surfaces (Sa, Sb) of a multilayer tablet. Particularly, a multilayer structure obtained by, in tableting, forming a convex portion for forming the concave portion on at least the upper punch, and preliminarily compressing all layers in the multilayer tablet with the upper punch to form a concave portion having the same shape with a depth of not less than 0.1 mm on the upper surface of all layers, wherein the powder materials of the next layer are protruding into the concave portion, is a preferable embodiment.
摘要翻译： 根据本发明，提供了显示抑制层分离的多层片剂及其制备方法。 在多层片剂的前表面（Sa，Sb）的至少一个表面Sa上形成有不小于0.1mm的深度的凹部的凹部。 特别是，通过在至少在上冲头上形成用于形成凹部的凸部的压片成型，并用上冲头预先压缩多层片剂中的所有层而形成具有相同形状的凹部而获得的多层结构， 在所有层的上表面上的深度不小于0.1mm，其中下一层的粉末材料突出到凹部中，是优选的实施方案。
-
-
-
-
-
搜索结果
6 条记录 (耗时 0.024 秒)