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公开(公告)号：US08268300B2
公开(公告)日：2012-09-18
申请号：US13024718
申请日：2011-02-10
申请人： Hiroshi Ujiie , Yoshiaki Suzuki , Masaya Iwaki , Takanori Uchida
发明人： Hiroshi Ujiie , Yoshiaki Suzuki , Masaya Iwaki , Takanori Uchida
IPC分类号： A61K31/74
CPC分类号： A61L31/04 , A61K31/00 , A61L2400/18 , A61L2430/36
摘要： It is an object of the present invention to provide a polymer material, the histocompatibility of which has been improved by irradiation of ion beam, which prevents an aneurysm having a risk of rupture from actually rupturing. The present invention provides a material for treating aneurysms, which is composed of a polymer material containing carbon as a constitutional element, and which is produced by modifying at least a portion of the surface thereof by ion bombardment.
摘要翻译： 本发明的一个目的是提供一种通过离子束的照射改善了组织相容性的聚合物材料，其防止了具有破裂风险的动脉瘤的实际破裂。 本发明提供一种治疗动脉瘤的材料，其由含有碳作为构成元素的高分子材料构成，其通过离子轰击改性其表面的至少一部分而制成。
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公开(公告)号：US20070185570A1
公开(公告)日：2007-08-09
申请号：US10568694
申请日：2004-08-18
申请人： Hiroshi Ujiie , Yoshiaki Suzuki , Masaya Iwaki , Takanori Uchida
发明人： Hiroshi Ujiie , Yoshiaki Suzuki , Masaya Iwaki , Takanori Uchida
IPC分类号： A61F2/06
CPC分类号： A61L31/04 , A61K31/00 , A61L2400/18 , A61L2430/36
摘要： It is an object of the present invention to provide a polymer material, the histocompatibility of which has been improved by irradiation of ion beam, which prevents an aneurysm having a risk of rupture from actually rupturing. The present invention provides a material for treating aneurysms, which is composed of a polymer material containing carbon as a constitutional element, and which is produced by modifying at least a portion of the surface thereof by ion bombardment.
摘要翻译： 本发明的一个目的是提供一种通过离子束的照射改善了组织相容性的聚合物材料，其防止了具有破裂风险的动脉瘤的实际破裂。 本发明提供一种治疗动脉瘤的材料，其由含有碳作为构成元素的高分子材料构成，其通过离子轰击改性其表面的至少一部分而制成。
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公开(公告)号：US20060051340A1
公开(公告)日：2006-03-09
申请号：US10542577
申请日：2004-01-16
申请人： Takanori Uchida , Noriko Shinya , Hiroshi Kaetsu
发明人： Takanori Uchida , Noriko Shinya , Hiroshi Kaetsu
CPC分类号： A61L15/32 , A61F13/36 , A61F2013/00472 , A61L15/26 , A61L2400/04 , Y10T442/2508 , Y10T442/2525 , Y10T442/2861 , Y10T442/696 , C08L65/04
摘要： A safe and effective hemostatic material is provided. A hemostatic material comprising as an effective ingredient thrombin and fibrinogen characterized in that a bioabsorbable synthetic nonwoven fabric is used as a supporting material. The use of the hemostatic material of the present invention allows for quick and thorough hemostasis for both projectile bleeding and exudative bleeding.
摘要翻译： 提供安全有效的止血材料。 一种止血材料，其包含作为有效成分的凝血酶和纤维蛋白原，其特征在于使用生物可吸收的合成非织造织物作为支撑材料。 使用本发明的止血材料可以快速和彻底地止血用于射弹出血和渗出性出血。
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公开(公告)号：US09162318B2
公开(公告)日：2015-10-20
申请号：US14006192
申请日：2012-03-27
申请人： Sachio Oki , Kiichi Kakei , Tomotake Hirata , Takayuki Takasugi , Yasuyuki Kaneno , Noboru Mochizuki , Takanori Uchida
发明人： Sachio Oki , Kiichi Kakei , Tomotake Hirata , Takayuki Takasugi , Yasuyuki Kaneno , Noboru Mochizuki , Takanori Uchida
CPC分类号： B23K20/126 , B23K11/317 , B23K11/318 , B23K20/123 , B23K20/1245 , B23K20/125 , B23K20/1265
摘要： A friction stir processing apparatus comprises a tool, a processing head retaining the tool, a support table retaining the workpiece, and a cylinder unit biasing the support table toward the tool. The tool having a probe projecting from a shoulder surface, for performing friction stir processing on a workpiece made of a metal material. The processing head is pressing the tool against the workpiece so as to relatively shift the tool in a processing direction. The friction stir processing apparatus comprises load control means for controlling to constantly keep the bias force of the cylinder unit so as to constantly keep pressurizing force of the tool pressing the workpiece. It is thus possible to perform friction stir processing with excellent quality even when the workpiece has a different thickness or is made of a different material.
摘要翻译： 摩擦搅拌处理装置包括工具，保持工具的加工头，保持工件的支撑台和将支撑台朝向工具偏置的气缸单元。 所述工具具有从肩部表面突出的探针，用于对由金属材料制成的工件进行摩擦搅拌处理。 加工头部将工具压靠在工件上，以使工具在加工方向上相对移动。 摩擦搅拌处理装置包括用于控制恒定地保持气缸单元的偏压力的负载控制装置，以便不断保持工具对工件的加压力。 因此，即使当工件具有不同的厚度或由不同的材料制成时，也可以以优异的质量执行摩擦搅拌处理。
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公开(公告)号：US20060127460A1
公开(公告)日：2006-06-15
申请号：US10534715
申请日：2003-11-12
CPC分类号： A61L15/44 , A61K47/6953 , A61L15/26 , A61L15/32 , A61L15/64 , A61L33/0041 , A61L2300/418 , A61L2400/04 , Y10T442/2525 , Y10T442/2566 , C08L67/04
摘要： A safe and effective hemostatic is provided. The invention relates to a bioabsorbable synthetic nonwoven fabric holding thrombin as an effective ingredient and a hemostatic comprising said bioabsorbable synthetic nonwoven fabric. The bioabsorbable synthetic nonwoven fabric holding thrombin in accordance with the present invention may be prepared by a process which comprises the steps of immersing a bioabsorbable synthetic nonwoven fabric into a solution containing thrombin and of lyophilizing the obtained nonwoven fabric. The bioabsorbable synthetic nonwoven fabric holding thrombin in accordance with the present invention allows for quicker and more effective hemostasis.
摘要翻译： 提供安全有效的止血剂。 本发明涉及一种保持凝血酶作为有效成分的生物可吸收合成无纺布和包含所述生物可吸收合成无纺织物的止血剂。 根据本发明的保持凝血酶的生物吸收性合成无纺布可以通过包括以下步骤的方法制备，所述方法包括将生物可吸收的合成非织造织物浸入含有凝血酶的溶液中并将所得的无纺织物冻干。 根据本发明的保持凝血酶的生物可吸收合成非织造织物可以更快更有效地止血。
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公开(公告)号：US20130253580A1
公开(公告)日：2013-09-26
申请号：US13884710
申请日：2011-11-07
申请人： Zenetsu Suzuki , Masao Ikeda , Takanori Uchida , Osamu Ichiki , Shirou Oka
发明人： Zenetsu Suzuki , Masao Ikeda , Takanori Uchida , Osamu Ichiki , Shirou Oka
IPC分类号： A61B17/00
CPC分类号： A61B17/00491 , A61B2017/00495 , B05B7/0475 , B05B7/0491 , B05B7/0876 , B05B7/2429 , B05B7/2472 , B05B11/02
摘要： An adhesive applicator for biological tissue (100) includes a nozzle body (1), a gas inlet (2), medical fluid inlets (3a, 3b), medical fluid outlets (4a, 4b), medical fluid tubes (5a, 5b), a gas outlet (6), communication paths (8a, 8b), and a check valve (7b). The gas outlet (6) is located close to the medical fluid outlets (4a, 4b), and configured to eject gas loaded through the gas inlet (2) in the nozzle body (1) to thereby atomize medical fluids and mix them together. The communication paths (8a, 8b) communicate between inside of the nozzle body (1) and inside of the medical fluid tube (5b). The check valve (7b) is located between the communication paths (8a, 8b) and the medical fluid inlet (3b). The check valve (7b) only allows one-way flow of the medical fluid from the medical fluid inlet (3b) into the medical fluid tube (5b).
摘要翻译： 用于生物组织（100）的粘合剂施加器包括喷嘴体（1），气体入口（2），医用流体入口（3a，3b），医用流体出口（4a，4b），药液流体管（5a，5b） ，气体出口（6），连通路径（8a，8b）和止回阀（7b）。 气体出口（6）位于医疗流体出口（4a，4b）附近，并且构造成喷射通过喷嘴体（1）中的气体入口（2）装载的气体，从而使医用流体雾化并混合在一起。 通路（8a，8b）在喷嘴体（1）的内部和医用流体管（5b）的内部连通。 止回阀（7b）位于连通通路（8a，8b）和医用流体入口（3b）之间。 止回阀（7b）仅允许医用流体从医用流体入口（3b）单向流入医用流体管（5b）。
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公开(公告)号：US08043629B2
公开(公告)日：2011-10-25
申请号：US11941779
申请日：2007-11-16
CPC分类号： A61L15/44 , A61K47/6953 , A61L15/26 , A61L15/32 , A61L15/64 , A61L33/0041 , A61L2300/418 , A61L2400/04 , Y10T442/2525 , Y10T442/2566 , C08L67/04
摘要： A safe and effective hemostatic is provided. The invention relates to a bioabsorbable synthetic nonwoven fabric holding thrombin as an effective ingredient and a hemostatic comprising said bioabsorbable synthetic nonwoven fabric. The bioabsorbable synthetic nonwoven fabric holding thrombin in accordance with the present invention may be prepared by a process which comprises the steps of immersing a bioabsorbable synthetic nonwoven fabric into a solution containing thrombin and of lyophilizing the obtained nonwoven fabric. The bioabsorbable synthetic nonwoven fabric holding thrombin in accordance with the present invention allows for quicker and more effective hemostasis.
摘要翻译： 提供安全有效的止血剂。 本发明涉及一种保持凝血酶作为有效成分的生物可吸收合成无纺布和包含所述生物可吸收合成无纺织物的止血剂。 根据本发明的保持凝血酶的生物吸收性合成无纺布可以通过包括以下步骤的方法制备，所述方法包括将生物可吸收的合成非织造织物浸入含有凝血酶的溶液中并将所得的无纺织物冻干。 根据本发明的保持凝血酶的生物可吸收合成非织造织物可以更快更有效地止血。
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公开(公告)号：US5980866A
公开(公告)日：1999-11-09
申请号：US945882
申请日：1997-11-13
CPC分类号： A61L24/106 , A61B17/00491 , A61B2017/00495 , Y10S514/822
摘要： An adhesive for tissue capable of uniformly forming a high concentration of fibrin so as to provide a high closing effect is disclosed. The adhesive for tissue comprises a fibrinogen solution and a thrombin solution which solutions are separated from each other. The adhesive is to be mixed and spray coated together with a sterile gas and has a volume ratio of the fibrinogen solution to the thrombin solution of about 2:1 to 10:1. This adhesive is to be sprayed together with a sterile gas for the adhesion or closing of living tissue of a human being or animal.
摘要翻译： PCT No.PCT / JP97 / 00818 Sec。 371日期：1997年11月13日 102（e）1997年11月13日PCT PCT 1997年3月14日PCT公布。 公开号WO97 / 33633 1997年9月18日公开了能够均匀地形成高浓度纤维蛋白以提供高闭合效果的组织的粘合剂。 用于组织的粘合剂包括纤维蛋白原溶液和溶液彼此分离的凝血酶溶液。 将粘合剂混合并用无菌气体喷涂，并且纤维蛋白原溶液与凝血酶溶液的体积比为约2:1至10:1。 该粘合剂将与无菌气体一起喷洒以用于人或动物的活组织的粘附或闭合。
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公开(公告)号：US20140034709A1
公开(公告)日：2014-02-06
申请号：US14006192
申请日：2012-03-27
申请人： Sachio Oki , Kiichi Kakei , Tomotake Hirata , Takayuki Takasugi , Yasuyuki Kaneno , Noboru Mochizuki , Takanori Uchida
发明人： Sachio Oki , Kiichi Kakei , Tomotake Hirata , Takayuki Takasugi , Yasuyuki Kaneno , Noboru Mochizuki , Takanori Uchida
IPC分类号： B23K20/12
CPC分类号： B23K20/126 , B23K11/317 , B23K11/318 , B23K20/123 , B23K20/1245 , B23K20/125 , B23K20/1265
摘要： A friction stir processing apparatus comprises a tool, a processing head retaining the tool, a support table retaining the workpiece, and a cylinder unit biasing the support table toward the tool. The tool having a probe projecting from a shoulder surface, for performing friction stir processing on a workpiece made of a metal material. The processing head is pressing the tool against the workpiece so as to relatively shift the tool in a processing direction. The friction stir processing apparatus comprises load control means for controlling to constantly keep the bias force of the cylinder unit so as to constantly keep pressurizing force of the tool pressing the workpiece. It is thus possible to perform friction stir processing with excellent quality even when the workpiece has a different thickness or is made of a different material.
摘要翻译： 摩擦搅拌处理装置包括工具，保持工具的加工头，保持工件的支撑台和将支撑台朝向工具偏置的气缸单元。 所述工具具有从肩部表面突出的探针，用于对由金属材料制成的工件进行摩擦搅拌处理。 加工头部将工具压靠在工件上，以使工具在加工方向上相对移动。 摩擦搅拌处理装置包括用于控制恒定地保持气缸单元的偏压力的负载控制装置，以便不断保持工具对工件的加压力。 因此，即使当工件具有不同的厚度或由不同的材料制成时，也可以以优异的质量执行摩擦搅拌处理。
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公开(公告)号：US06251370B1
公开(公告)日：2001-06-26
申请号：US09299916
申请日：1999-04-28
IPC分类号： A61L904
CPC分类号： A61L24/106 , A61B17/00491 , A61B2017/00495 , Y10S514/822
摘要： An adhesive for tissue capable of uniformly forming a high concentration of fibrin so as to provide a high closing effect is disclosed. The adhesive for tissue comprises a fibrinogen solution and a thrombin solution which solutions are separated from each other. The adhesive is to be mixed and spray coated together with a sterile gas and has a volume ratio of the fibrinogen solution to the thrombin solution of about 2:1 to 10:1. This adhesive is to be sprayed together with a sterile gas for the adhesion or closing of living tissue of a human being or animal.
摘要翻译： 公开了能够均匀地形成高浓度纤维蛋白以提供高闭合效果的用于组织的粘合剂。 用于组织的粘合剂包括纤维蛋白原溶液和溶液彼此分离的凝血酶溶液。 将粘合剂混合并用无菌气体喷涂，并且纤维蛋白原溶液与凝血酶溶液的体积比为约2:1至10:1。 该粘合剂将与无菌气体一起喷洒以用于人或动物的活组织的粘附或闭合。
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