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公开(公告)号：US20080090998A1
公开(公告)日：2008-04-17
申请号：US11982700
申请日：2007-11-01
申请人： Mark Abad , Jaclyn Cleveland , Bettina Darveaux , Angie Ferguson , Barry Goldman , Balasulojini Karunanandaa , Maria McDonald , Daniel Riggsbee , Mahmood Sayed , Erin Slaten
发明人： Mark Abad , Jaclyn Cleveland , Bettina Darveaux , Angie Ferguson , Barry Goldman , Balasulojini Karunanandaa , Maria McDonald , Daniel Riggsbee , Mahmood Sayed , Erin Slaten
CPC分类号： C12N15/8273 , C07K14/415 , C12N9/0008 , C12N15/8261 , C12N15/8271 , C12Y102/01016 , C12Y102/01024 , Y02A40/146
摘要： Transgenic seed for crops with improved traits are provided by trait-improving recombinant DNA where plants grown from such transgenic seed exhibit one or more improved traits as compared to a control plant. Exemplary recombinant DNA expresses a succinate semialdehyde dehydrogenase.
摘要翻译： 具有改良性状的作物的转基因种子由改良重组DNA提供，其中与对照植物相比，从这种转基因种子生长的植物表现出一种或多种改良的性状。 示例性重组DNA表达琥珀酸半醛脱氢酶。
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公开(公告)号：US20060075522A1
公开(公告)日：2006-04-06
申请号：US11188298
申请日：2005-07-22
申请人： Jaclyn Cleveland , Erin Slaten , Mahmood Sayed , Mark Abad , Balasulojini Karunanandaa , Barry Goldman , Daniel Riggsbee , Bettina Darveaux , Angie Ferguson , Maria McDonald
发明人： Jaclyn Cleveland , Erin Slaten , Mahmood Sayed , Mark Abad , Balasulojini Karunanandaa , Barry Goldman , Daniel Riggsbee , Bettina Darveaux , Angie Ferguson , Maria McDonald
CPC分类号： C12N15/8273 , C07K14/415 , C12N9/0008 , C12N15/8261 , C12N15/8271 , C12Y102/01016 , C12Y102/01024 , Y02A40/146
摘要： Transgenic seed for crops with improved traits are provided by trait-improving recombinant DNA where plants grown from such transgenic seed exhibit one or more improved traits as compared to a control plant. Exemplary recombinant DNA expresses a succinate semialdehyde dehydrogenase.
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公开(公告)号：US09115368B2
公开(公告)日：2015-08-25
申请号：US11982700
申请日：2007-11-01
申请人： Mark Scott Abad , Jaclyn Cleveland , Bettina Darveaux , Angie Ferguson , Barry S. Goldman , Balasulojini Karunanandaa , Maria McDonald , Daniel Riggsbee , Mahmood Sayed , Erin Slaten
发明人： Mark Scott Abad , Jaclyn Cleveland , Bettina Darveaux , Angie Ferguson , Barry S. Goldman , Balasulojini Karunanandaa , Maria McDonald , Daniel Riggsbee , Mahmood Sayed , Erin Slaten
IPC分类号： A01H5/00 , C12N15/82 , C12N15/63 , C07K14/415 , C12N9/02
CPC分类号： C12N15/8273 , C07K14/415 , C12N9/0008 , C12N15/8261 , C12N15/8271 , C12Y102/01016 , C12Y102/01024 , Y02A40/146
摘要： Transgenic seed for crops with improved traits are provided by trait-improving recombinant DNA where plants grown from such transgenic seed exhibit one or more improved traits as compared to a control plant. Of particular interest are transgenic plants that have increased yield. The invention also provides recombinant DNA molecules for expression of a protein.
摘要翻译： 具有改良性状的作物的转基因种子由改良重组DNA提供，其中与对照植物相比，从这种转基因种子生长的植物表现出一种或多种改良的性状。 特别感兴趣的是具有增加的产量的转基因植物。 本发明还提供用于表达蛋白质的重组DNA分子。
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公开(公告)号：US20060041961A1
公开(公告)日：2006-02-23
申请号：US11087099
申请日：2005-03-22
申请人： Mark Abad , Jason Cotter , Robert D'Ordine , Angie Ferguson , Barry Goldman , Karen Hartsuyker , Balasulojini Karunanandaa , Susan Norris , Steven Rounsley , Joshua Stein , James Todd , Li Zhou
发明人： Mark Abad , Jason Cotter , Robert D'Ordine , Angie Ferguson , Barry Goldman , Karen Hartsuyker , Balasulojini Karunanandaa , Susan Norris , Steven Rounsley , Joshua Stein , James Todd , Li Zhou
CPC分类号： C12N15/8261 , C07K14/415 , C12N15/8271 , C12N15/8273 , Y02A40/146
摘要： Transgenic seed for crops with improved traits are provided by trait-improving recombinant DNA where plants grown from such transgenic seed exhibit one or more improved traits as compared to a control plant. Of particular interest are transgenic plants that have increased yield. The present invention also provides recombinant DNA molecules for expression of a protein, and recombinant DNA molecules for expression of mRNA complementary to at least a portion of an mRNA native to the target plant for use in gene suppression to suppress the expression of a protein.
摘要翻译： 具有改良性状的作物的转基因种子由改良重组DNA提供，其中与对照植物相比，从这种转基因种子生长的植物表现出一种或多种改良的性状。 特别感兴趣的是具有增加的产量的转基因植物。 本发明还提供了用于表达蛋白质的重组DNA分子和用于表达与目标植物天然的mRNA的至少一部分互补的mRNA的重组DNA分子，以用于基因抑制以抑制蛋白质的表达。
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公开(公告)号：US20110265221A1
公开(公告)日：2011-10-27
申请号：US12218251
申请日：2008-07-10
申请人： Mark Abad , Jeffrey E. Ahrens , Alice Clara Augustine , Erin Bell , Robert J. Bensen , Paolo Castiglioni , R. Eric Cerny , Shobha Char , Xianfeng Chen , Jaishree M. Chittoor-Vijayanath , Maureen Daley , Jill Deikman , Molian Deng , Todd Dezwaan , Stephen Duff , Michael D. Edgerton , Bradon J. Fabbri , Jason Fenner , Karen K. Gabbert , Meghan Galligan Donnarummo , Barry S. Goldman , Deborah J. Hawkins , Steve He , G. Richard Johnson , Balasulojini Karunanandaa , Garrett J. Lee , Paul Loida , Savitha Madappa , Robert J. Meister , Donald E. Nelson , Anand Pandravada , Obed Patty , Ming Peng , Marie Petracek , M.S. Rajani , Dhanalakshmi Ramachandra , Monica Ravanello , Thomas G. Ruff , Rick A. Sanders , Beth Savidge , Steven H. Schwartz , Padmini Sudarshana , Jindong Sun , Rebecca L. Thompson-Mize , Virginia Ursin , Dale L. Val , Srikanth Venkatachalayya , T.V. Venkatesh , K.R. Vidya , K. Vijayalakshmi , Todd C. Weber , Jingrui Wu , Zhidong Xie , Wei Zheng
发明人： Mark Abad , Jeffrey E. Ahrens , Alice Clara Augustine , Erin Bell , Robert J. Bensen , Paolo Castiglioni , R. Eric Cerny , Shobha Char , Xianfeng Chen , Jaishree M. Chittoor-Vijayanath , Maureen Daley , Jill Deikman , Molian Deng , Todd Dezwaan , Stephen Duff , Michael D. Edgerton , Bradon J. Fabbri , Jason Fenner , Karen K. Gabbert , Meghan Galligan Donnarummo , Barry S. Goldman , Deborah J. Hawkins , Steve He , G. Richard Johnson , Balasulojini Karunanandaa , Garrett J. Lee , Paul Loida , Savitha Madappa , Robert J. Meister , Donald E. Nelson , Anand Pandravada , Obed Patty , Ming Peng , Marie Petracek , M.S. Rajani , Dhanalakshmi Ramachandra , Monica Ravanello , Thomas G. Ruff , Rick A. Sanders , Beth Savidge , Steven H. Schwartz , Padmini Sudarshana , Jindong Sun , Rebecca L. Thompson-Mize , Virginia Ursin , Dale L. Val , Srikanth Venkatachalayya , T.V. Venkatesh , K.R. Vidya , K. Vijayalakshmi , Todd C. Weber , Jingrui Wu , Zhidong Xie , Wei Zheng
CPC分类号： C12N15/8273 , A01H1/02 , C12N15/8241 , C12N15/8247 , C12N15/8251 , C12N15/8261 , C12N15/8271 , C12Q1/6895 , C12Q2600/13 , Y02A40/146
摘要： This invention provides recombinant DNA constructs, transgenic plant nuclei and cells with such recombinant DNA construct for expression of proteins that are useful for imparting enhanced agronomic trait(s) to transgenic crop plants. This invention also provides transgenic plants and progeny seed comprising the transgenic plant cells where the plants are selected for having an enhanced trait selected from the group of traits consisting of enhanced water use efficiency, enhanced cold tolerance, increased yield, enhanced nitrogen use efficiency, enhanced seed protein and enhanced seed oil. Also disclosed are methods for manufacturing transgenic seed and plants with enhanced traits.
摘要翻译： 本发明提供重组DNA构建体，转基因植物核和具有这样的重组DNA构建体的细胞，用于表达可用于赋予转基因作物植物增强的农艺性状的蛋白质。 本发明还提供包含转基因植物细胞的转基因植物和后代种子，其中植物被选择用于具有增强的性状，所述性状选自由增强的水利用效率，增强的耐寒性，增加的产量，增强的氮利用效率，增强的氮利用效率， 种子蛋白和增强种子油。 还公开了用于制备具有增强特征的转基因种子和植物的方法。
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公开(公告)号：US20110252501A1
公开(公告)日：2011-10-13
申请号：US11893915
申请日：2007-08-17
申请人： Mark Abad , Molian Deng , Sephen Duff , Mary Fernandes , Karen K. Gabbert , Julie A. Alvarez , Kristen A. Bennett , Paolo Castiglioni , Jill Deikman , Jason Fenner , Danyang Ke , Barry S. Goldman , Qungang Qi , Thomas G. Ruff , Rebecca L. Thompason-Mize , Jingrui Wu , Thomas R. Adams , Robert Bensen , Jacqueline E. Heard , Donald E. Nelson , Erin Bell , R. Eric Cerny , Jaishree M. Chittoor-Vijayanath , Bradon J. Fabbri , Balasulojini Karunanandaa , John R. LeDeaux , Xianfeng Chen , Meghan Galligan-Donnarummo , Deborah J. Hawkins , Garrett J. Lee , Obed Patty , Rick A. Sanders , Beth Savidge , Dale L. Val , Wei Zheng , Thomas J. Savage , Rajani Monnanda Somaiah , Sreekanta Suma , Jindong Sun , Tymagondlu Venkatesh , Nanfei Xu , Mahindra Anuradha , Alice Clara Augustine , Farah Deeba , Ramachandra Dhanalakshmi , Savitha Madappa , Badami S. Pranesh , M. S. Rajani , G. Ramamohan , S. Sangeetha , Char Shobha , Padmini Sudarshana , K. R. Vidva , Srikanth Venkatachalayya , Tymagondlu Venkatesh
发明人： Mark Abad , Molian Deng , Sephen Duff , Mary Fernandes , Karen K. Gabbert , Julie A. Alvarez , Kristen A. Bennett , Paolo Castiglioni , Jill Deikman , Jason Fenner , Danyang Ke , Barry S. Goldman , Qungang Qi , Thomas G. Ruff , Rebecca L. Thompason-Mize , Jingrui Wu , Thomas R. Adams , Robert Bensen , Jacqueline E. Heard , Donald E. Nelson , Erin Bell , R. Eric Cerny , Jaishree M. Chittoor-Vijayanath , Bradon J. Fabbri , Balasulojini Karunanandaa , John R. LeDeaux , Xianfeng Chen , Meghan Galligan-Donnarummo , Deborah J. Hawkins , Garrett J. Lee , Obed Patty , Rick A. Sanders , Beth Savidge , Dale L. Val , Wei Zheng , Thomas J. Savage , Rajani Monnanda Somaiah , Sreekanta Suma , Jindong Sun , Tymagondlu Venkatesh , Nanfei Xu , Mahindra Anuradha , Alice Clara Augustine , Farah Deeba , Ramachandra Dhanalakshmi , Savitha Madappa , Badami S. Pranesh , M. S. Rajani , G. Ramamohan , S. Sangeetha , Char Shobha , Padmini Sudarshana , K. R. Vidva , Srikanth Venkatachalayya , Tymagondlu Venkatesh
CPC分类号： C12N15/8275 , A01H1/02 , C12N15/8247 , C12N15/8251 , C12N15/8261 , C12N15/8271 , C12N15/8273 , C12N15/8274 , C12Q1/6895 , C12Q2600/13 , C12Q2600/158 , Y02A40/146
摘要： This invention provides transgenic plant cells with recombinant DNA for expression of proteins that are useful for imparting enhanced agronomic trait(s) to transgenic crop plants. This invention also provides transgenic plants and progeny seed comprising the transgenic plant cells where the plants are selected for having an enhanced trait selected from the group of traits consisting of enhanced water use efficiency, enhanced cold tolerance, increased yield, enhanced nitrogen use efficiency, enhanced seed protein and enhanced seed oil. Also disclosed are methods for manufacturing transgenic seed and plants with enhanced traits.
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公开(公告)号：US20090044288A1
公开(公告)日：2009-02-12
申请号：US12218975
申请日：2008-07-18
申请人： Mark Abad , Murtaza Alibhai , Alice Clara Augustine , Amarjit Basra , Erin Bell , Terry L. Bradshaw , Paolo Castiglioni , Jaishree M. Chittoor-Vijayanath , Jill Deikman , Molian Deng , Michael D. Edgerton , Karen K. Gabbert , Barry S. Goldman , Balasulojini Karunanandaa , Susanne Kjemtrup-Lovelace , Timothy J. Leland , Adrian A. Lund , Linda Lutfiyya , Marcus McNabnay , Donald E. Nelson , Thomas G. Ruff , Beth Savidge , Paul Schaffer , Padmini Sudarshana , K. Sumathy , Carolyn Thai , Rebecca L. Thompson-Mize , Carl P. Urwin , H.G. Veena , T.V. Venkatesh , Steven T. Voss , Zhidong Xie
发明人： Mark Abad , Murtaza Alibhai , Alice Clara Augustine , Amarjit Basra , Erin Bell , Terry L. Bradshaw , Paolo Castiglioni , Jaishree M. Chittoor-Vijayanath , Jill Deikman , Molian Deng , Michael D. Edgerton , Karen K. Gabbert , Barry S. Goldman , Balasulojini Karunanandaa , Susanne Kjemtrup-Lovelace , Timothy J. Leland , Adrian A. Lund , Linda Lutfiyya , Marcus McNabnay , Donald E. Nelson , Thomas G. Ruff , Beth Savidge , Paul Schaffer , Padmini Sudarshana , K. Sumathy , Carolyn Thai , Rebecca L. Thompson-Mize , Carl P. Urwin , H.G. Veena , T.V. Venkatesh , Steven T. Voss , Zhidong Xie
CPC分类号： C12N15/8247 , A01H1/04 , C12N15/8251 , C12N15/8261 , C12N15/8273 , Y02A40/146
摘要： This invention provides transgenic plant cells with recombinant DNA for expression of proteins that are useful for imparting enhanced agronomic trait(s) to transgenic crop plants. This invention also provides transgenic plants and progeny seed comprising the transgenic plant cells where the plants are selected for having an enhanced trait selected from the group of traits consisting, of enhanced water use efficiency, enhanced cold tolerance, increased yield, enhanced nitrogen use efficiency, enhanced seed protein and enhanced seed oil. Also disclosed are methods for manufacturing transgenic seed and plants with enhanced trait.
摘要翻译： 本发明提供具有用于表达蛋白质的重组DNA的转基因植物细胞，其可用于赋予转基因作物植物增强的农艺性状。 本发明还提供包含转基因植物细胞的转基因植物和后代种子，其中植物被选择用于具有增强的性状，所述性状选自由增强的水利用效率，增强的耐寒性，增加的产量，增强的氮利用效率， 增强的种子蛋白和增强的种子油。 还公开了用于制备具有增强特征的转基因种子和植物的方法。
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8.发明授权Transgenic plants containing altered levels of sterol compounds and tocopherols 有权含有改变水平的固醇化合物和生育酚的转基因植物公开(公告)号：US07709666B2
公开(公告)日：2010-05-04
申请号：US10647517
申请日：2004-01-16
申请人： Mylavarapu Venkatramesh , David R. Corbin , B. Ganesh Bhat , Sekhar S. Boddupalli , Robert J. Grebenok , Ganesh M. Kishore , Kathryn D. Lardizabal , Michael W. Lassner , Shaukat H. Rangwala , Balasulojini Karunanandaa
发明人： Mylavarapu Venkatramesh , David R. Corbin , B. Ganesh Bhat , Sekhar S. Boddupalli , Robert J. Grebenok , Ganesh M. Kishore , Kathryn D. Lardizabal , Michael W. Lassner , Shaukat H. Rangwala , Balasulojini Karunanandaa
IPC分类号： C07C59/147
CPC分类号： C12N9/001 , C12N15/8243
摘要： Provided are recombinant constructs comprising DNA sequences encoding enzymes effective in altering the biosynthesis and accumulation of sterol compounds and tocopherols in transgenic plants. Also provided are methods of using such constructs to produce transgenic plants, seeds of which contain elevated levels of sitostanol and/or sitostanol esters, and α-tocopherol, as well as reduced levels of campesterol and campestanol and their corresponding esters. These seeds also contain the novel sterol brassicastanol. Oil obtained from seeds of such transgenic plants is also provided. This oil can be used to prepare food and pharmaceutical compositions effective in lowering the level of low density lipoprotein cholesterol in blood serum. In addition, novel DNA sequences encoding plant steroid 5α-reductases are also disclosed.
摘要翻译： 提供了包含编码有效改变转基因植物中甾醇化合物和生育酚的生物合成和积累的酶的DNA序列的重组构建体。 还提供了使用这种构建体产生转基因植物的方法，其种子含有升高水平的谷甾烷醇和/或谷甾烷醇酯和α-生育酚，以及降低水平的菜油甾醇和菜油甾醇及其相应的酯。 这些种子还含有新的甾醇黄豆糖醇。 还提供了从这种转基因植物的种子获得的油。 该油可用于制备有效降低血清中低密度脂蛋白胆固醇水平的食品和药物组合物。 此外，还公开了编码植物类固醇5α-还原酶的新型DNA序列。
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9.发明授权Gamma tocopherol methyltransferase coding sequences from Brassica and uses thereof 有权来自芸苔属的伽马生育酚甲基转移酶编码序列及其用途公开(公告)号：US07595382B2
公开(公告)日：2009-09-29
申请号：US11776429
申请日：2007-07-11
申请人： Alison Van Eenennaam , Henry E. Valentin , Balasulojini Karunanandaa , Ming Hao , Eric Aasen , Charlene Levering
发明人： Alison Van Eenennaam , Henry E. Valentin , Balasulojini Karunanandaa , Ming Hao , Eric Aasen , Charlene Levering
CPC分类号： C12N9/1007 , C12N15/8243
摘要： The present invention relates to genes associated with the tocopherol biosynthesis pathway. More particularly, the present invention provides and includes nucleic acid molecules, proteins, and antibodies associated with genes that encode polypeptides that have methyltransferase activity. The present invention also provides methods for utilizing such agents, for example in gene isolation, gene analysis and the production of transgenic plants. Moreover, the present invention includes transgenic plants modified to express the aforementioned polypeptides. In addition, the present invention includes methods for the production of products from the tocopherol biosynthesis pathway.
摘要翻译： 本发明涉及与生育酚生物合成途径相关的基因。 更具体地，本发明提供并包括与编码具有甲基转移酶活性的多肽的基因相关的核酸分子，蛋白质和抗体。 本发明还提供了利用这些试剂的方法，例如在基因分离，基因分析和转基因植物的生产中。 此外，本发明包括被修饰以表达上述多肽的转基因植物。 此外，本发明包括从生育酚生物合成途径生产产物的方法。
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10.发明授权Gamma tocopherol methyltransferase coding sequence identified in Cuphea and uses thereof 有权在Cuphea中鉴定的γ-生育酚甲基转移酶编码序列及其用途公开(公告)号：US07553952B2
公开(公告)日：2009-06-30
申请号：US11776423
申请日：2007-07-11
申请人： Alison Van Eenennaam , Henry E. Valentin , Balasulojini Karunanandaa , Ming Hao , Eric Aasen , Charlene Levering
发明人： Alison Van Eenennaam , Henry E. Valentin , Balasulojini Karunanandaa , Ming Hao , Eric Aasen , Charlene Levering
CPC分类号： C12N9/1007 , C12N15/8243
摘要： The present invention relates to genes associated with the tocopherol biosynthesis pathway. More particularly, the present invention provides and includes nucleic acid molecules, proteins, and antibodies associated with genes that encode polypeptides that have methyltransferase activity. The present invention also provides methods for utilizing such agents, for example in gene isolation, gene analysis and the production of transgenic plants. Moreover, the present invention includes transgenic plants modified to express the aforementioned polypeptides. In addition, the present invention includes methods for the production of products from the tocopherol biosynthesis pathway.
摘要翻译： 本发明涉及与生育酚生物合成途径相关的基因。 更具体地，本发明提供并包括与编码具有甲基转移酶活性的多肽的基因相关的核酸分子，蛋白质和抗体。 本发明还提供了利用这些试剂的方法，例如在基因分离，基因分析和转基因植物的生产中。 此外，本发明包括被修饰以表达上述多肽的转基因植物。 此外，本发明包括从生育酚生物合成途径生产产物的方法。
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