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公开(公告)号:US20130041034A1
公开(公告)日:2013-02-14
申请号:US12660865
申请日:2010-03-04
申请人: Jagat Singh , Joseph-Zev Shainhouse , Bradley S. Caler , Robert Dominic King-Smith , Lisa Marie Grierson , Maria Burian , Jonathan Wilkin , Edward T. Kisak , John M. Newsam
发明人: Jagat Singh , Joseph-Zev Shainhouse , Bradley S. Caler , Robert Dominic King-Smith , Lisa Marie Grierson , Maria Burian , Jonathan Wilkin , Edward T. Kisak , John M. Newsam
IPC分类号: A61K31/196 , A61B19/02 , A61P19/02
CPC分类号: A61K31/196 , A61K8/35 , A61K8/36 , A61K8/361 , A61K8/42 , A61K9/0014 , A61K31/10 , A61K45/06 , A61K47/10 , A61K47/20 , A61K47/38 , A61Q17/02 , A61Q17/04 , A61K2300/00
摘要: The field involves compositions useful for pain relief, including diclofenac solution and gel formulations, in particular methods of use thereof, articles of manufacture and kits that provide novel preclinical, clinical and other information to users.
摘要翻译: 该领域涉及可用于缓解疼痛的组合物,包括双氯芬酸溶液和凝胶制剂,特别是其使用方法,制品和试剂盒,其向用户提供临床前,临床和其他信息。
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公开(公告)号:US20150366830A1
公开(公告)日:2015-12-24
申请号:US14804793
申请日:2015-07-21
申请人: Jagat Singh , Joseph Zev Shainhouse , Bradley S. Galer , Robert Dominic King-Smith , Lisa Marie Grierson , Maria Burian , Jonathan Wilkin , Edward T. Kisak , John M. Newsam
发明人: Jagat Singh , Joseph Zev Shainhouse , Bradley S. Galer , Robert Dominic King-Smith , Lisa Marie Grierson , Maria Burian , Jonathan Wilkin , Edward T. Kisak , John M. Newsam
CPC分类号: A61K31/196 , A61K8/35 , A61K8/36 , A61K8/361 , A61K8/42 , A61K9/0014 , A61K31/10 , A61K45/06 , A61K47/10 , A61K47/20 , A61K47/38 , A61Q17/02 , A61Q17/04 , A61K2300/00
摘要: The field involves compositions useful for pain relief, including diclofenac solution and gel formulations, in particular methods of use thereof, articles of manufacture and kits that provide novel preclinical, clinical and other information to users.
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公开(公告)号:US08546450B1
公开(公告)日:2013-10-01
申请号:US12459998
申请日:2009-07-10
申请人: Jagat Singh , Joseph Zev Shainhouse , Bradley S. Galer , Robert Dominic King-Smith , Lisa Marie Grierson , Maria Burian , Jonathan Wilkin , Edward T. Kisak , John M. Newsam
发明人: Jagat Singh , Joseph Zev Shainhouse , Bradley S. Galer , Robert Dominic King-Smith , Lisa Marie Grierson , Maria Burian , Jonathan Wilkin , Edward T. Kisak , John M. Newsam
IPC分类号: A01N37/10 , A01N41/10 , A61K31/19 , A61K31/10 , C07C63/04 , C07C315/00 , C07C317/00
CPC分类号: A61K31/196 , A61K45/06 , A61K2300/00
摘要: The field involves compositions useful for pain relief, including diclofenac solution and gel formulations, in particular methods of use thereof, articles of manufacture and kits that provide novel preclinical, clinical and other information to users.
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公开(公告)号:US08618164B2
公开(公告)日:2013-12-31
申请号:US12660865
申请日:2010-03-04
申请人: Jagat Singh , Joseph Zev Shainhouse , Bradley S. Galer , Robert Dominic King-Smith , Lisa Marie Grierson , Maria Burian , Jonathan Wilkin , Edward T. Kisak , John M. Newsam
发明人: Jagat Singh , Joseph Zev Shainhouse , Bradley S. Galer , Robert Dominic King-Smith , Lisa Marie Grierson , Maria Burian , Jonathan Wilkin , Edward T. Kisak , John M. Newsam
IPC分类号: A01N37/12 , A01N37/44 , A61K31/24 , A01N41/10 , A61K31/10 , C07C229/00 , C07C315/00 , C07C317/00
CPC分类号: A61K31/196 , A61K8/35 , A61K8/36 , A61K8/361 , A61K8/42 , A61K9/0014 , A61K31/10 , A61K45/06 , A61K47/10 , A61K47/20 , A61K47/38 , A61Q17/02 , A61Q17/04 , A61K2300/00
摘要: The field involves compositions useful for pain relief, including diclofenac solution and gel formulations, in particular methods of use thereof, articles of manufacture and kits that provide novel preclinical, clinical and other information to users.
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公开(公告)号:US08217078B1
公开(公告)日:2012-07-10
申请号:US12914867
申请日:2010-10-28
申请人: Jagat Singh , Joseph Zev Shainhouse , Bradley S. Galer , Robert Dominic King-Smith , Lisa Marie Grierson , Maria Burian , Jonathan Wilkin , Edward T. Kisak , John M. Newsam
发明人: Jagat Singh , Joseph Zev Shainhouse , Bradley S. Galer , Robert Dominic King-Smith , Lisa Marie Grierson , Maria Burian , Jonathan Wilkin , Edward T. Kisak , John M. Newsam
IPC分类号: A01N37/12 , A01N37/44 , A01N37/10 , A01N41/10 , A61K31/195 , A61K31/19 , A61K31/10 , C07C229/00 , C07C315/00 , C07C317/00
CPC分类号: A61K31/196 , A61K8/35 , A61K8/36 , A61K8/361 , A61K8/42 , A61K9/0014 , A61K31/10 , A61K45/06 , A61K47/10 , A61K47/20 , A61K47/38 , A61Q17/02 , A61Q17/04 , A61K2300/00
摘要: The field involves compositions useful for pain relief, including diclofenac solution and gel formulations, in particular methods of use thereof, articles of manufacture and kits that provide novel preclinical, clinical and other information to users.
摘要翻译: 该领域涉及可用于缓解疼痛的组合物,包括双氯芬酸溶液和凝胶制剂,特别是其使用方法,制品和试剂盒,其向用户提供临床前,临床和其他信息。
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公开(公告)号:US20120232152A1
公开(公告)日:2012-09-13
申请号:US13511287
申请日:2010-11-26
申请人: Dominic King-Smith , Bradley S. Galer , John M. Newsam , Nadir Buyuktimkin , Edward T. Kisak , Jagat Singh
发明人: Dominic King-Smith , Bradley S. Galer , John M. Newsam , Nadir Buyuktimkin , Edward T. Kisak , Jagat Singh
IPC分类号: A61K31/192 , A61P29/00
CPC分类号: A61K31/192 , A61K9/0014 , A61K47/10 , A61K47/14
摘要: The present application relates to a topical formulation comprising ibuprofen, a hydroalcoholic based solvent system, a C1-4alcohol ester of citric acid, and a surfactant. The formulation shows physical stability over more than one month at ambient temperature and is colourless, essentially odorless, and has a pH value of about 6.5. The formulation of the application shows two to four times improved ibuprofen flux compared to a standard composition.
摘要翻译: 本申请涉及包含布洛芬,基于水醇的溶剂体系,柠檬酸的C 1-4醇酯和表面活性剂的局部制剂。 该配方在环境温度下显示超过一个月的物理稳定性,为无色,基本上无臭,pH值约为6.5。 与标准组合物相比,该应用的配方显示了改善的布洛芬通量的2-4倍。
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公开(公告)号:US20130136805A1
公开(公告)日:2013-05-30
申请号:US13816056
申请日:2011-08-12
申请人: Servet Buyuktimkin , Nadir Buyuktimkin , Edward T. Kisak , John M. Newsam , Dominic King-Smith , Jagat Singh , Rainer Martin
发明人: Servet Buyuktimkin , Nadir Buyuktimkin , Edward T. Kisak , John M. Newsam , Dominic King-Smith , Jagat Singh , Rainer Martin
IPC分类号: A61K9/12
CPC分类号: A61K9/122 , A61K9/0014 , A61K33/00 , A61K47/02 , A61K47/26 , A61K47/32 , A61K47/34 , A61K47/38
摘要: The present application relates to foamable compositions and foams comprising stabilized chlorite, including stabilized chlorite solutions such as Oxovasin™, and to medical uses thereof, in particular for wound healing. The foamable compositions comprise at least one foaming agent, stabilized chlorite, water and optionally, a buffering agent.
摘要翻译: 本发明涉及可发泡组合物和包含稳定的亚氯酸盐的泡沫,包括稳定的亚氯酸盐溶液,例如Oxovasin TM,以及其医疗用途,特别是用于伤口愈合。 可发泡组合物包含至少一种发泡剂,稳定的亚氯酸盐,水和任选的缓冲剂。
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公开(公告)号:US20110288123A1
公开(公告)日:2011-11-24
申请号:US13127470
申请日:2009-11-05
申请人: Edward T. Kisak , R. Dominic King-Smith , Bradley S. Galer , John M. Newsam , Nadir Buyuktimkin , Servet Buyuktimkin , Jagat Singh
发明人: Edward T. Kisak , R. Dominic King-Smith , Bradley S. Galer , John M. Newsam , Nadir Buyuktimkin , Servet Buyuktimkin , Jagat Singh
IPC分类号: A61K31/47 , A61K31/167 , A61P29/00 , A61K31/24 , A61P23/00 , A61K31/245 , A61K31/445
CPC分类号: A61K31/167 , A61K9/0014 , A61K47/10 , A61K47/26
摘要: The present invention provides compositions and methods that are useful for treatment of pain associated with acute herpes zoster. The aqueous compositions are non-stinging and non-irritating.
摘要翻译: 本发明提供了可用于治疗与急性带状疱疹相关的疼痛的组合物和方法。 含水组合物是非刺激性且无刺激性的。
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公开(公告)号:US08470886B2
公开(公告)日:2013-06-25
申请号:US13511287
申请日:2010-11-26
申请人: Dominic King-Smith , Bradley S. Galer , John M. Newsam , Nadir Buyuktimkin , Servet Buyuktimkin , Edward T. Kisak , Jagat Singh
发明人: Dominic King-Smith , Bradley S. Galer , John M. Newsam , Nadir Buyuktimkin , Servet Buyuktimkin , Edward T. Kisak , Jagat Singh
IPC分类号: A61K31/192
CPC分类号: A61K31/192 , A61K9/0014 , A61K47/10 , A61K47/14
摘要: The present application relates to a topical formulation comprising ibuprofen, a hydroalcoholic based solvent system, a C1-4alcohol ester of citric acid, and a surfactant. The formulation shows physical stability over more than one month at ambient temperature and is colorless, essentially odorless, and has a pH value of about 6.5. The formulation of the application shows two to four times improved ibuprofen flux compared to a standard composition.
摘要翻译: 本申请涉及包含布洛芬,基于水醇的溶剂体系,柠檬酸的C 1-4醇酯和表面活性剂的局部制剂。 该配方在环境温度下显示超过一个月的物理稳定性,为无色,基本上无臭,pH值约为6.5。 与标准组合物相比,该应用的配方显示了改善的布洛芬通量的2-4倍。
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公开(公告)号:US20130316020A1
公开(公告)日:2013-11-28
申请号:US13984443
申请日:2012-02-09
申请人: Servet Buyuktimkin , Nadir Buyuktimkin , Edward T. Kisak , Dominic King-Smith , John M. Newsam , Jagat Singh
发明人: Servet Buyuktimkin , Nadir Buyuktimkin , Edward T. Kisak , Dominic King-Smith , John M. Newsam , Jagat Singh
IPC分类号: A61L15/44
CPC分类号: A61L15/44 , A61L15/26 , A61L15/425 , A61L15/46 , A61L2300/106 , A61L2300/404 , C08L75/04
摘要: This application described a wound dressing comprising an absorbent material, an effective amount of chlorite and an amount of a base to provide a pH of the dressing material greater than or equal to about (10). Advantageously, the wound dressings of the present application provide a convenient source of chlorite that is stable and easy to use.
摘要翻译: 本申请描述了包含吸收材料,有效量的亚氯酸盐和一定量的基底的伤口敷料,以提供大于或等于约(10)的敷料材料的pH。 有利地,本申请的伤口敷料提供了稳定且易于使用的方便的绿泥石源。
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