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公开(公告)号:US20060040927A1
公开(公告)日:2006-02-23
申请号:US11208962
申请日:2005-08-22
申请人: James Blake , Jay Fell , John Fischer , Robert Hendricks , John Robinson , Stacey Spencer , Peter Stengel
发明人: James Blake , Jay Fell , John Fischer , Robert Hendricks , John Robinson , Stacey Spencer , Peter Stengel
IPC分类号: A61K31/5415 , C07D417/02
CPC分类号: C07D471/04 , C07D413/06 , C07D417/04 , C07D495/04
摘要: Compounds having the formula I wherein A, m and R1 are herein defined are Hepatitis C virus polymerase inhibitors. Also disclosed are compositions and methods for treating diseases mediated by HCV and for inhibiting hepatitis replication. Also disclosed are processes for making the compounds and synthetic intermediates used in the process
摘要翻译: 本文定义的具有式I的化合物,其中A,m和R 1是丙型肝炎病毒聚合酶抑制剂。 还公开了用于治疗由HCV介导的疾病和用于抑制肝炎复制的组合物和方法。 还公开了制备该方法中使用的化合物和合成中间体的方法
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公开(公告)号:US20060252785A1
公开(公告)日:2006-11-09
申请号:US11413872
申请日:2006-04-28
申请人: James Blake , Jay Fell , John Fischer , Robert Hendricks , Stacey Spencer , Peter Stengel
发明人: James Blake , Jay Fell , John Fischer , Robert Hendricks , Stacey Spencer , Peter Stengel
IPC分类号: C07D417/02 , C07D417/14 , A61K31/513 , A61K31/4709 , A61K31/4439 , A61K31/425
CPC分类号: C07D417/06 , C07D417/04 , C07D417/14
摘要: Compounds having the formula I wherein A, m and R1 are herein defined are Hepatitis C virus NS5b polymerase inhibitors. Also disclosed are compositions and methods for inhibiting hepatitis replication, processes for making the compounds and synthetic intermediates used in the process
摘要翻译: 本文定义的具有式I的化合物,其中A,m和R 1是丙型肝炎病毒NS5b聚合酶抑制剂。 还公开了抑制肝炎复制的组合物和方法,制备该方法中使用的化合物和合成中间体的方法
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公开(公告)号:US20080095739A1
公开(公告)日:2008-04-24
申请号:US11706777
申请日:2007-02-15
申请人: Jay Fell , Peter Mohr , Peter Stengel
发明人: Jay Fell , Peter Mohr , Peter Stengel
IPC分类号: A61K31/5415 , A61K31/542 , A61K38/17 , A61K38/20 , A61K38/21 , C07D417/04 , C07D513/04
CPC分类号: C07D417/04 , C07D513/04
摘要: Compounds having the formula Ia or Ib wherein R1, R2, R3 and R4 are as defined herein are Hepatitis C virus NS5b polymerase inhibitors. Also disclosed are compositions and methods for treating an HCV infection and inhibiting HCV replication.
摘要翻译: 具有式Ia或Ib的化合物,其中R 1,R 2,R 3和R 4定义如上所定义 本文是丙型肝炎病毒NS5b聚合酶抑制剂。 还公开了用于治疗HCV感染和抑制HCV复制的组合物和方法。
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