3',6-diisopentenyl-2',4'-dihydroxy-5,7-dimethoxy-isoflavan and related
compounds useful as anxiolytic agents and avermectin antidotes
    10.
    发明授权
    3',6-diisopentenyl-2',4'-dihydroxy-5,7-dimethoxy-isoflavan and related compounds useful as anxiolytic agents and avermectin antidotes 失效
    3',6-二异戊烯基-2',4'-二羟基-5,7-二甲氧基异黄酮和可用作抗焦虑剂和除虫菌素解毒剂的相关化合物

    公开(公告)号:US4639466A

    公开(公告)日:1987-01-27

    申请号:US656554

    申请日:1984-10-01

    IPC分类号: C07D311/38 A61K31/35

    CPC分类号: C07D311/38

    摘要: 3',6-Diisopentenyl-2',4'-dihydroxy-5,7-dimethoxyisoflavan has been isolated from Glycyrrhiza uralensis Fisch. It has been found that this compound and other related compounds are potent stimulators of benzodiazepine receptors and thereby useful as effective anxiolytic agents. Furthermore, these compounds have been found to be potent antidotes of avermectin.

    摘要翻译: 3',6-二异戊烯基-2',4'-二羟基-5,7-二甲氧基异黄酮已从甘草中分离出来。 已经发现,该化合物和其它相关化合物是苯并二氮杂受体的有效刺激剂,因此可用作有效的抗焦虑剂。 此外,已经发现这些化合物是阿维菌素的有效解毒剂。