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    Method for performing renal replacement therapy including producing sterile replacement fluid in a renal replacement therapy unit
    6.
    发明授权
    Method for performing renal replacement therapy including producing sterile replacement fluid in a renal replacement therapy unit 有权
    用于进行肾脏替代治疗的方法，包括在肾脏替代治疗单元中产生无菌置换液体

    公开(公告)号：US06649063B2

    公开(公告)日：2003-11-18

    申请号：US09905246

    申请日：2001-07-12

    申请人： James M. Brugger ,  Jeffrey H. Burbank ,  Dennis M. Treu

    发明人： James M. Brugger ,  Jeffrey H. Burbank ,  Dennis M. Treu

    IPC分类号： B01D6100

    CPC分类号： B01D61/145 ,  A61M1/1692 ,  A61M1/3437 ,  A61M1/3441 ,  A61M1/3444 ,  A61M1/3462 ,  A61M1/3465 ,  A61M1/3643 ,  A61M1/3644 ,  A61M2205/12 ,  A61M2205/705 ,  B01D61/18 ,  C02F1/444

    摘要： A method and device for renal replacement therapy is described that sterile-filters solution that can subsequently be used as a replacement fluid in the same unit. The devices and methods include a pump that can be reversed from its normal forward-pumping direction to sterilize a container of replacement fluid to produce sterile replacement fluid. The sterile replacement fluid is captured in a fluid bag. Upon sterilization of the contents of the container, the pump switches to run in its normal forward-pumping direction. The sterile replacement fluid produced by the previous process is now injected into a patient to perform renal replacement therapy. The waste produced during the renal replacement therapy can be trapped in the container that previously held the non-sterile solution. Systems for sterile filtration and subsequent renal replacement therapy that include pre-connected, sterilized, disposable kits for fluid management and batch collection of sterilized fluid are also described.

    摘要翻译： 描述了用于肾替代治疗的方法和装置，其可以随后在相同单元中用作替换流体的无菌过滤器溶液。 装置和方法包括可以从其正常向前泵送方向反向的泵，以对替换流体的容器进行消毒以产生无菌置换液体。 无菌置换液被捕获在流体袋中。 在消毒容器的内容物时，泵切换到正常的正向泵送方向。 现在将由先前方法产生的无菌置换液注射到患者中进行肾脏替代疗法。 在肾脏替代治疗期间产生的废物可以被捕获在以前保持非无菌溶液的容器中。 还描述了用于无菌过滤和随后的肾脏替代疗法的系统，其包括用于流体管理和无菌液体的批量收集的预先连接的，灭菌的一次性套件。

    Pressure detector for fluid circuits
    8.
    发明授权
    Pressure detector for fluid circuits 有权
    流体回路压力检测器

    公开(公告)号：US07337674B2

    公开(公告)日：2008-03-04

    申请号：US11160586

    申请日：2005-06-29

    申请人： Jeffrey H. Burbank ,  James M. Brugger ,  Dennis M. Treu ,  Christopher McDowell

    发明人： Jeffrey H. Burbank ,  James M. Brugger ,  Dennis M. Treu ,  Christopher McDowell

    IPC分类号： G01L7/00

    CPC分类号： G01L7/024 ,  A61M1/3639

    摘要： A pressure measurement device usable for monitoring pressure of fluids such as blood, waste, and replacement fluid in a blood treatment system provides a reliable signal and other benefits by virtue of a number of features of the various embodiments disclosed. The pressure of fluid carried by a vessel or tube is measured by measuring a change in shape of the vessel or tube via a sensor element contacting it. Materials, shape, and mechanical support cooperatively ensure that the little inelastic strain occurs and pressure measurements are repeatable. The embodiments are compatible with the use of disposable vessels and tubes.

    摘要翻译： 可用于监测血液处理系统中的血液，废物和置换液体等流体的压力的压力测量装置由于所公开的各种实施方式的许多特征而提供可靠的信号和其他益处。 容器或管所携带的流体的压力通过经由与其接触的传感器元件测量容器或管的形状的变化来测量。 材料，形状和机械支撑协调地确保发生小的非弹性应变，压力测量可重复。 这些实施例与一次性容器和管的使用兼容。

    Flow-through peritoneal dialysis systems and methods with on-line dialysis solution regeneration
    10.
    发明授权
    Flow-through peritoneal dialysis systems and methods with on-line dialysis solution regeneration 失效

    公开(公告)号：US06254567B1

    公开(公告)日：2001-07-03

    申请号：US09512132

    申请日：2000-02-23

    申请人： Dennis M. Treu ,  Jeffrey H. Burbank ,  James M. Brugger

    发明人： Dennis M. Treu ,  Jeffrey H. Burbank ,  James M. Brugger

    IPC分类号： A61M100

    CPC分类号： A61M1/1696 ,  A61M1/28 ,  A61M1/284 ,  A61M1/288

    摘要： Peritoneal dialysis is performed by circulating peritoneal dialysis solution through a peritoneal cavity by conveying peritoneal dialysis solution through an inlet branch into the peritoneal cavity and by withdrawing peritoneal dialysis solution through an outlet branch from the peritoneal cavity. Peritoneal dialysis solution in the outlet branch is conveyed along a first side of a porous membrane while conveying a regeneration solution containing at least one regenerating agent along a second side of the porous membrane. The membrane is configured to transport the regenerating agent into the peritoneal dialysis solution while transporting waste from the peritoneal dialysis solution into the regeneration solution, thereby creating a regenerated peritoneal dialysis solution. The regenerated peritoneal dialysis solution is circulated through the inlet branch into the peritoneal cavity.