-
1.
公开(公告)号:US08962026B2
公开(公告)日:2015-02-24
申请号:US12567571
申请日:2009-09-25
申请人: James R. Baker, Jr. , Mark R. Hemmila , Stewart C. Wang , Tarek Hamouda , John J. LiPuma , Jessica A. Knowlton , Paul E. Makidon , Luz P. Blanco , Jeffery V. Groom, II , Anna U. Bielinska
发明人: James R. Baker, Jr. , Mark R. Hemmila , Stewart C. Wang , Tarek Hamouda , John J. LiPuma , Jessica A. Knowlton , Paul E. Makidon , Luz P. Blanco , Jeffery V. Groom, II , Anna U. Bielinska
IPC分类号: A61K9/107
CPC分类号: A61K31/198 , A61K9/1075 , A61K31/045 , A61K31/047 , A61K31/14 , A61K31/341 , A61K31/4425 , A61K45/06
摘要: The present invention relates to therapeutic nanoemulsion compositions and to methods of utilizing the same. In particular, nanoemulsion compositions are described herein that find use in the treatment and/or prevention of infection (e.g., respiratory infection (e.g., associated with cystic fibrosis)), in burn wound management, and in immunogenic compositions (e.g., comprising a Burkholderia antigen) that generate an effective immune response (e.g., against a bacterial species of the genus Burkholderia) in a subject administered the immunogenic composition. Compositions and methods of the present invention find use in, among other things, clinical (e.g. therapeutic and preventative medicine), industrial, and research applications.
摘要翻译: 本发明涉及治疗性纳米乳剂组合物及其利用方法。 特别地,本文描述了用于治疗和/或预防感染(例如,呼吸道感染(例如,与囊性纤维化相关)),烧伤伤口管理和免疫原性组合物(例如,包含伯克霍尔德氏菌(Burkholderia))的纳米乳剂组合物 抗原),其在施用免疫原性组合物的受试者中产生有效的免疫应答(例如,针对伯克霍尔德氏菌属的细菌物种)。 本发明的组合物和方法尤其可用于临床(例如治疗和预防性药物),工业和研究应用。
-
公开(公告)号:US20100203139A1
公开(公告)日:2010-08-12
申请号:US12567571
申请日:2009-09-25
申请人: James R. Baker, JR. , Mark R. Hemmila , Stewart C. Wang , Tarek Hamouda , John J. LiPuma , Jessica A. Knowlton , Paul E. Makidon , Luz P. Blanco , Jeffery V. Groom, II , Anna U. Bielinska
发明人: James R. Baker, JR. , Mark R. Hemmila , Stewart C. Wang , Tarek Hamouda , John J. LiPuma , Jessica A. Knowlton , Paul E. Makidon , Luz P. Blanco , Jeffery V. Groom, II , Anna U. Bielinska
CPC分类号: A61K31/198 , A61K9/1075 , A61K31/045 , A61K31/047 , A61K31/14 , A61K31/341 , A61K31/4425 , A61K45/06
摘要: The present invention relates to therapeutic nanoemulsion compositions and to methods of utilizing the same. In particular, nanoemulsion compositions are described herein that find use in the treatment and/or prevention of infection (e.g., respiratory infection (e.g., associated with cystic fibrosis)), in burn wound management, and in immunogenic compositions (e.g., comprising a Burkholderia antigen) that generate an effective immune response (e.g., against a bacterial species of the genus Burkholderia) in a subject administered the immunogenic composition. Compositions and methods of the present invention find use in, among other things, clinical (e.g. therapeutic and preventative medicine), industrial, and research applications.
-
公开(公告)号:US09492525B2
公开(公告)日:2016-11-15
申请号:US13543493
申请日:2012-07-06
IPC分类号: A61K9/107 , A61P37/04 , A61K39/155 , A61K39/12 , C07K16/10 , C12N7/00 , A61K9/00 , A61K9/06 , A61K9/127 , A61K9/51 , A61K31/716 , A61K31/722 , A61K39/00
CPC分类号: A61K39/12 , A61K9/0019 , A61K9/06 , A61K9/1075 , A61K9/1271 , A61K9/5115 , A61K31/716 , A61K31/722 , A61K47/26 , A61K47/38 , A61K47/44 , A61K2039/5252 , A61K2039/543 , A61K2039/55555 , A61K2039/55566 , A61K2039/55583 , C07K16/1027 , C07K2317/33 , C07K2317/76 , C12N7/00 , C12N2760/18521 , C12N2760/18522 , C12N2760/18534 , A61K2300/00
摘要: The present invention relates to RSV vaccines and methods for inducing an immune response to RSV in a subject comprising administering an RSV vaccine.
摘要翻译: 本发明涉及用于在受试者中诱导对RSV的免疫应答的RSV疫苗和方法,包括施用RSV疫苗。
-
公开(公告)号:US20110091556A1
公开(公告)日:2011-04-21
申请号:US11507084
申请日:2006-08-18
申请人: James R. Baker, JR. , Tarek Hamouda , Amy Shih , Andrzej Myc
发明人: James R. Baker, JR. , Tarek Hamouda , Amy Shih , Andrzej Myc
IPC分类号: A61K9/107 , A61K31/4425 , A61K31/14 , A61P31/00
CPC分类号: A61K9/1075 , A61K45/06
摘要: The present invention relates to compositions and methods for decreasing the infectivity, morbidity, and rate of mortality associated with a variety of pathogenic organisms and viruses. The present invention also relates to methods and compositions for decontaminating areas colonized or otherwise infected by pathogenic organisms and viruses. Moreover, the present invention relates to methods and compositions for decreasing the infectivity of pathogenic organisms in foodstuffs. In particular, decreased pathogenic organism infectivity, morbidity, and mortality is accomplished by contacting the pathogenic organism with an oil-in-water nanoemulsion comprising an oil, an organic solvent, and a surfactant dispersed in an aqueous phase.
摘要翻译: 本发明涉及用于降低与各种致病生物体和病毒有关的感染性,发病率和死亡率的组合物和方法。 本发明还涉及用于对由致病菌和病毒定殖或以其它方式感染的区域进行净化的方法和组合物。 此外,本发明涉及用于降低食品中病原生物体的感染性的方法和组合物。 特别地,通过使致病生物与包含分散在水相中的油,有机溶剂和表面活性剂的水包油纳米乳液接触来实现降低的致病生物体的感染性,发病率和死亡率。
-
公开(公告)号:US20090143476A1
公开(公告)日:2009-06-04
申请号:US11928427
申请日:2007-10-30
申请人: James R. Baker, JR. , Tarek Hamouda , Amy Shih , Andrzej Myc
发明人: James R. Baker, JR. , Tarek Hamouda , Amy Shih , Andrzej Myc
CPC分类号: A61K31/522 , A61K8/062 , A61K8/068 , A61K9/1075 , A61K31/14 , A61K45/06 , A61K2800/413 , A61Q17/005 , B82Y5/00 , Y02A50/393 , Y02A50/402 , Y02A50/463 , Y02A50/469 , Y02A50/471 , Y02A50/473 , Y02A50/475 , Y02A50/481 , Y10S514/937 , Y10S514/938 , A61K2300/00
摘要: The present invention relates to compositions and methods for decreasing the infectivity, morbidity, and rate of mortality associated with a variety of pathogenic organisms and viruses. The present invention also relates to methods and compositions for decontaminating areas colonized or otherwise infected by pathogenic organisms and viruses. Moreover, the present invention relates to methods and compositions for decreasing the infectivity of pathogenic organisms in foodstuffs.
-
公开(公告)号:US20130011443A1
公开(公告)日:2013-01-10
申请号:US13543493
申请日:2012-07-06
IPC分类号: A61K9/107 , A61P37/04 , A61K39/155 , B82Y5/00
CPC分类号: A61K39/12 , A61K9/0019 , A61K9/06 , A61K9/1075 , A61K9/1271 , A61K9/5115 , A61K31/716 , A61K31/722 , A61K47/26 , A61K47/38 , A61K47/44 , A61K2039/5252 , A61K2039/543 , A61K2039/55555 , A61K2039/55566 , A61K2039/55583 , C07K16/1027 , C07K2317/33 , C07K2317/76 , C12N7/00 , C12N2760/18521 , C12N2760/18522 , C12N2760/18534 , A61K2300/00
摘要: The present invention relates to RSV vaccines and methods for inducing an immune response to RSV in a subject comprising administering an RSV vaccine.
摘要翻译: 本发明涉及用于在受试者中诱导对RSV的免疫应答的RSV疫苗和方法,包括施用RSV疫苗。
-
公开(公告)号:US20120219602A1
公开(公告)日:2012-08-30
申请号:US13407695
申请日:2012-02-28
IPC分类号: A61K9/107 , A61P31/22 , A61K31/20 , A61K31/4164 , B82Y5/00
CPC分类号: A61K9/1075 , A61K9/0014
摘要: The present invention relates to methods for treating, killing, and/or inhibiting the growth of Herpes viruses in human subjects comprising topically administering to a human subject in need thereof a nanoemulsion composition having antiviral properties.
摘要翻译: 本发明涉及用于治疗,杀死和/或抑制人类受试者中疱疹病毒生长的方法,包括向有需要的人类受试者局部施用具有抗病毒性质的纳米乳剂组合物。
-
公开(公告)号:US08232320B2
公开(公告)日:2012-07-31
申请号:US11928427
申请日:2007-10-30
申请人: James R. Baker, Jr. , Tarek Hamouda , Amy Shih , Andrzej Myc
发明人: James R. Baker, Jr. , Tarek Hamouda , Amy Shih , Andrzej Myc
IPC分类号: A01N33/12 , A61K31/14 , A61K31/235 , A61K31/74 , A61K9/14
CPC分类号: A61K31/522 , A61K8/062 , A61K8/068 , A61K9/1075 , A61K31/14 , A61K45/06 , A61K2800/413 , A61Q17/005 , B82Y5/00 , Y02A50/393 , Y02A50/402 , Y02A50/463 , Y02A50/469 , Y02A50/471 , Y02A50/473 , Y02A50/475 , Y02A50/481 , Y10S514/937 , Y10S514/938 , A61K2300/00
摘要: The present invention relates to compositions and methods for decreasing the infectivity, morbidity, and rate of mortality associated with a variety of pathogenic organisms and viruses. The present invention also relates to methods and compositions for decontaminating areas colonized or otherwise infected by pathogenic organisms and viruses. Moreover, the present invention relates to methods and compositions for decreasing the infectivity of pathogenic organisms in foodstuffs.
-
公开(公告)号:US20090143477A1
公开(公告)日:2009-06-04
申请号:US11928447
申请日:2007-10-30
申请人: James R. Baker, JR. , Tarek Hamouda , Amy Shih , Andrzej Myc
发明人: James R. Baker, JR. , Tarek Hamouda , Amy Shih , Andrzej Myc
CPC分类号: A61K31/522 , A61K8/062 , A61K8/068 , A61K9/1075 , A61K31/14 , A61K45/06 , A61K2800/413 , A61Q17/005 , B82Y5/00 , Y02A50/393 , Y02A50/402 , Y02A50/463 , Y02A50/469 , Y02A50/471 , Y02A50/473 , Y02A50/475 , Y02A50/481 , Y10S514/937 , Y10S514/938 , A61K2300/00
摘要: The present invention relates to compositions and methods for decreasing the infectivity, morbidity, and rate of mortality associated with a variety of pathogenic organisms and viruses. The present invention also relates to methods and compositions for decontaminating areas colonized or otherwise infected by pathogenic organisms and viruses. Moreover, the present invention relates to methods and compositions for decreasing the infectivity of pathogenic organisms in foodstuffs.
摘要翻译: 本发明涉及用于降低与各种致病生物体和病毒有关的感染性,发病率和死亡率的组合物和方法。 本发明还涉及用于对由致病菌和病毒定殖或以其它方式感染的区域进行净化的方法和组合物。 此外,本发明涉及用于降低食品中病原生物体的感染性的方法和组合物。
-
公开(公告)号:US06559189B2
公开(公告)日:2003-05-06
申请号:US09891086
申请日:2001-06-25
申请人: James R. Baker, Jr. , Tarek Hamouda , Amy Shih , Andrzej Myc
发明人: James R. Baker, Jr. , Tarek Hamouda , Amy Shih , Andrzej Myc
IPC分类号: A61K3114
CPC分类号: A61K8/062 , A61K8/06 , A61K9/1075 , A61K31/14 , A61K45/06 , A61K2800/21 , A61K2800/413 , A61Q5/006 , A61Q11/00 , A61Q15/00 , A61Q17/005 , B82Y5/00 , A61K2300/00
摘要: The present invention relates to compositions and methods for decreasing the infectivity, morbidity, and rate of mortality associated with a variety of pathogenic organisms and viruses. The present invention also relates to methods and compositions for decontaminating areas colonized or otherwise infected by pathogenic organisms and viruses. Moreover, the present invention relates to methods and compositions for decreasing the infectivity of pathogenic organisms in foodstuffs.
-
-
-
-
-
-
-
-
-