Streptococcus vaccine compositions and methods of using the same
    4.
    发明授权
    Streptococcus vaccine compositions and methods of using the same 有权
    链球菌疫苗组合物及其使用方法

    公开(公告)号:US08668911B2

    公开(公告)日:2014-03-11

    申请号:US13320205

    申请日:2010-05-14

    IPC分类号: A61K39/09

    摘要: The present invention provides methods and compositions for the stimulation of immune responses. In particular, the present invention provides immunogenic nanoemulsion compositions and methods of using the same for the induction of immune responses (e.g., innate and/or adaptive immune responses (e.g., for generation of host immunity against a bacterial species of the genus Streptococcus (e.g., Streptococcus pneumoniae))). Compositions and methods of the present invention find use in, among other things, clinical (e.g. therapeutic and preventative medicine (e.g., vaccination)) and research applications.

    摘要翻译: 本发明提供了用于刺激免疫应答的方法和组合物。 特别地,本发明提供了免疫原性纳米乳剂组合物及其应用于诱导免疫应答的方法(例如,天然和/或适应性免疫应答(例如,用于产生针对链球菌属的细菌种的宿主免疫)(例如, ,肺炎链球菌)))。 本发明的组合物和方法尤其可用于临床(例如治疗和预防性药物(例如疫苗接种))和研究应用。

    Methods of preventing and treating microbial infections
    7.
    发明授权
    Methods of preventing and treating microbial infections 有权
    预防和治疗微生物感染的方法

    公开(公告)号:US06506803B1

    公开(公告)日:2003-01-14

    申请号:US09561111

    申请日:2000-04-28

    IPC分类号: A01N2500

    摘要: The present invention provides methods and compositions for inactivating bacteria including bacterial spores using an oil-in-water emulsion are provided. The oil-in-water emulsion comprises an oil, a surfactant and an organic phosphate-based solvent. These methods can be used to inactivate a wide variety of microorganisms including bacteria, bacterial spores, fungi, fungal spores and enveloped viruses.

    摘要翻译: 本发明提供了使用水包油乳液灭活包括细菌孢子在内的细菌的方法和组合物。 水包油乳液包含油,表面活性剂和有机磷酸盐基溶剂。 这些方法可用于灭活多种微生物,包括细菌,细菌孢子,真菌,真菌孢子和包膜病毒。

    Multifunctional nanodevice platform
    8.
    发明授权
    Multifunctional nanodevice platform 失效
    多功能纳米设备平台

    公开(公告)号:US06471968B1

    公开(公告)日:2002-10-29

    申请号:US09570198

    申请日:2000-05-12

    IPC分类号: C07H2104

    摘要: The present invention relates to novel therapeutic and diagnostic arrays. More particularly, the present invention is directed to dendrimer based multifunctional compositions and systems for use in disease diagnosis and therapy (e.g., cancer diagnosis and therapy). The compositions and systems generally comprise two or more separate components for targeting, imaging, sensing, and/or triggering release of a therapeutic or diagnostic material and monitoring the response to therapy of a cell or tissue (e.g., a tumor).

    摘要翻译: 本发明涉及新的治疗和诊断阵列。 更具体地,本发明涉及用于疾病诊断和治疗(例如癌症诊断和治疗)的基于树枝状大分子的多功能组合物和系统。 组合物和系统通常包含用于靶向,成像,感测和/或触发治疗或诊断材料释放并监测对细胞或组织(例如肿瘤)的治疗的反应的两个或更多个单独组分。