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公开(公告)号:US20080306087A1
公开(公告)日:2008-12-11
申请号:US11997424
申请日:2006-08-03
申请人: James R. Empfield , Michael Laplante , Megan Murphy King , Thomas R. Simpson , Maxime C. Tremblay , James M. Woods , Jingbo Yan
发明人: James R. Empfield , Michael Laplante , Megan Murphy King , Thomas R. Simpson , Maxime C. Tremblay , James M. Woods , Jingbo Yan
IPC分类号: A61K31/496 , A61P3/04 , A61P25/00 , A61P11/00 , A61P1/00 , A61K31/495 , C07D295/104 , C07D403/06 , C07D401/06 , C07D409/06
CPC分类号: C07D295/182 , C07D213/82 , C07D233/70 , C07D295/185 , C07D295/192 , C07D333/38
摘要: The present invention relates to compounds of formula (I) and processes for preparing such compounds, their use in the treatment of obesity, psychiatric and neurological disorders, to methods for their therapeutic use and to pharmaceutical compositions containing them.
摘要翻译: 本发明涉及式(I)化合物及其制备方法,它们在治疗肥胖,精神病和神经障碍中的应用,其治疗用途的方法和含有它们的药物组合物。
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公开(公告)号:US20100130477A1
公开(公告)日:2010-05-27
申请号:US12623585
申请日:2009-11-23
IPC分类号: A61K31/551 , C07D487/00 , C07D223/14 , A61K31/497 , A61P25/28 , A61P25/18 , A61P25/22 , A61P25/00 , A61P3/04
CPC分类号: C07D401/10 , C07D221/20 , C07D401/04 , C07D401/06 , C07D401/14
摘要: Disclosed herein is at least one spirocyclobutyl piperidine derivative, at least one pharmaceutical composition comprising at least one spirocyclobutyl piperidine derivative disclosed herein, and at least one method of using at least one spirocyclobutyl piperidine derivative disclosed herein for treating at least one histamine H3 receptor associated condition therewith.
摘要翻译: 本文公开了至少一种螺环丁基哌啶衍生物,至少一种包含本文公开的至少一种螺环丁基哌啶衍生物的药物组合物和至少一种使用本文公开的至少一种螺环丁基哌啶衍生物来治疗至少一种组胺H3受体相关病症 随之而来。
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