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公开(公告)号：US20150182338A1
公开(公告)日：2015-07-02
申请号：US14664684
申请日：2015-03-20
申请人： James R. KERMODE , Miles D. ALEXANDER , Michael P. BOUTILLETTE , Matthew T. DAVILA , Irene Bing Bie TAN
发明人： James R. KERMODE , Miles D. ALEXANDER , Michael P. BOUTILLETTE , Matthew T. DAVILA , Irene Bing Bie TAN
IPC分类号： A61F2/24
CPC分类号： A61F2/2487 , A61B17/12122 , A61B17/12172 , A61M1/1008 , A61M1/1018 , A61M1/1046 , A61M1/106 , A61M1/1068 , A61M1/107 , A61M1/1074 , A61M1/12 , A61M1/125 , A61M25/0067 , A61M25/0068 , A61M2205/32
摘要： Devices and systems including implants (which may be removable) and methods of using them for reducing ventricular volume. The implants described herein are cardiac implants that may be inserted into a patient's heart, particularly the left ventricle. The implant may support the heart wall, or may be secured to the heart wall. The implants are typically ventricular partitioning device for partitioning the ventricle into productive and non-productive regions in order to reduce the ventricular volume.
摘要翻译： 装置和系统包括植入物（可以是可移除的）和使用它们来减少心室容积的方法。 本文描述的植入物是可以插入患者心脏，特别是左心室的心脏植入物。 植入物可以支撑心脏壁，或者可以固定到心脏壁。 植入物通常是心室分配装置，用于将心室分成生产性和非生产性区域，以减少心室容积。
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公开(公告)号：US20160262892A1
公开(公告)日：2016-09-15
申请号：US15159715
申请日：2016-05-19
申请人： James R. KERMODE , Miles D. ALEXANDER , Michael P. BOUTILLETTE , Matthew T. DAVILA , Irene Bing Bie TAN
发明人： James R. KERMODE , Miles D. ALEXANDER , Michael P. BOUTILLETTE , Matthew T. DAVILA , Irene Bing Bie TAN
CPC分类号： A61F2/2487 , A61B17/12122 , A61B17/12172 , A61M1/1008 , A61M1/1018 , A61M1/1046 , A61M1/106 , A61M1/1068 , A61M1/107 , A61M1/1074 , A61M1/12 , A61M1/125 , A61M25/0067 , A61M25/0068 , A61M2205/32
摘要： Devices and systems including implants (which may be removable) and methods of using them for reducing ventricular volume. The implants described herein are cardiac implants that may be inserted into a patient's heart, particularly the left ventricle. The implant may support the heart wall, or may be secured to the heart wall. The implants are typically ventricular partitioning device for partitioning the ventricle into productive and non-productive regions in order to reduce the ventricular volume.
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公开(公告)号：US20140296624A1
公开(公告)日：2014-10-02
申请号：US14304834
申请日：2014-06-13
申请人： James R. KERMODE , Miles D. ALEXANDER , Michael P. BOUTILLETTE , Matthew T. DAVILA , Irene Bing Bie TAN
发明人： James R. KERMODE , Miles D. ALEXANDER , Michael P. BOUTILLETTE , Matthew T. DAVILA , Irene Bing Bie TAN
IPC分类号： A61F2/24
CPC分类号： A61F2/2487 , A61B17/12122 , A61B17/12172 , A61M1/1008 , A61M1/1018 , A61M1/1046 , A61M1/106 , A61M1/1068 , A61M1/107 , A61M1/1074 , A61M1/12 , A61M1/125 , A61M25/0067 , A61M25/0068 , A61M2205/32
摘要： Devices and systems including implants (which may be removable) and methods of using them for reducing ventricular volume. The implants described herein are cardiac implants that may be inserted into a patient's heart, particularly the left ventricle. The implant may support the heart wall, or may be secured to the heart wall. The implants are typically ventricular partitioning device for partitioning the ventricle into productive and non-productive regions in order to reduce the ventricular volume.
摘要翻译： 装置和系统包括植入物（可以是可移除的）和使用它们来减少心室容积的方法。 本文描述的植入物是可以插入患者心脏，特别是左心室的心脏植入物。 植入物可以支撑心脏壁，或者可以固定到心脏壁。 植入物通常是心室分配装置，用于将心室分成生产性和非生产性区域，以减少心室容积。
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公开(公告)号：US20160302924A1
公开(公告)日：2016-10-20
申请号：US15133080
申请日：2016-04-19
申请人： Michael P. BOUTILLETTE , James R. KERMODE , Miles D. ALEXANDER , Alexander KHAIRKHAHAN , Serjan D. NIKOLIC
发明人： Michael P. BOUTILLETTE , James R. KERMODE , Miles D. ALEXANDER , Alexander KHAIRKHAHAN , Serjan D. NIKOLIC
CPC分类号： A61B90/39 , A61B17/12022 , A61B17/12122 , A61B17/12172 , A61B2017/00243 , A61B2017/00526 , A61B2017/00867 , A61B2017/12054 , A61B2017/12095 , A61B2090/3966 , A61M25/09 , B29C43/18 , B29C65/18 , B29C66/1122 , B29C66/532 , B29C66/53261 , B29C66/545 , B29C66/636 , B29C66/71 , B29C66/712 , B29C66/727 , B29C66/729 , B29C66/81429 , B29C66/81431 , B29C66/8322 , B29C70/74 , B29L2031/753 , B29K2027/18 , B29K2023/06 , B29K2023/065
摘要： Systems for partitioning a ventricle of a heart include a partitioning device or implant, and an applicator for inserting, repositioning and/or removing the partitioning device. The implant may support the ventricle wall and may reduce the volume of the ventricle. The delivery system for delivering and deploying a partitioning device into a ventricle may include a catheter having a distal coupling element for coupling to a partitioning device in a collapsed configuration; the catheter may also have an expansion member for applying force to the partitioning device to fully expand it into a deployed configuration and to secure or seal it against the ventricle wall.
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公开(公告)号：US20150265405A1
公开(公告)日：2015-09-24
申请号：US14731161
申请日：2015-06-04
申请人： Michael P. BOUTILLETTE , James R. KERMODE , Miles D. ALEXANDER , Alexander KHAIRKHAHAN , Serjan D. NIKOLIC
发明人： Michael P. BOUTILLETTE , James R. KERMODE , Miles D. ALEXANDER , Alexander KHAIRKHAHAN , Serjan D. NIKOLIC
CPC分类号： A61F2/2487 , A61B17/00234 , A61B17/12022 , A61B17/12122 , A61B17/12172 , A61B2017/00243 , A61B2017/00292 , A61B2017/00867 , A61B2017/12054 , A61B2017/12081 , A61B2017/12095 , A61F2230/0093 , A61M5/007 , A61M25/007
摘要： Systems for partitioning a ventricle of a heart include a partitioning device or implant, and an applicator for inserting, repositioning and/or removing the partitioning device. The implant may support the ventricle wall and may reduce the volume of the ventricle. The delivery system for delivering and deploying a partitioning device into a ventricle may include a catheter having a distal coupling element for coupling to a partitioning device in a collapsed configuration; the catheter may also have an expansion member for applying force to the partitioning device to fully expand it into a deployed configuration and to secure or seal it against the ventricle wall.
摘要翻译： 用于分配心脏心室的系统包括分隔装置或植入物，以及用于插入，重新定位和/或移除分隔装置的施用器。 植入物可以支撑心室壁并且可以减小心室的体积。 用于将分配装置递送和部署到心室的递送系统可以包括具有用于以折叠构造耦合到分隔装置的远端联接元件的导管; 导管还可以具有用于向分隔装置施加力以将其完全展开成展开构型并将其固定或密封抵靠心室壁的扩张构件。
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6.发明申请公开(公告)号：US20130270735A1
公开(公告)日：2013-10-17
申请号：US13827927
申请日：2013-03-14
申请人： Miles D. ALEXANDER
发明人： Miles D. ALEXANDER
IPC分类号： A61B17/12
CPC分类号： A61B17/12122 , A61B17/12022 , A61B17/12172 , A61B2017/00243 , A61B2017/00867 , A61B2017/12054 , A61B2017/12095 , B29C43/18 , B29C65/12
摘要： Described herein are systems and methods for securing a polymeric sheet to rib components of a frame structure, wherein the rib components are jointed at a hub to form an expandable and collapsible implant. In general, the method may include the steps of decreasing a diameter of the frame structure; placing the frame structure into an assembly fixture, wherein the assembly fixture is configured to hold the frame structure in a loaded configuration with a decreased diameter; placing a polymeric sheet into the assembly fixture; and heating the assembly under pressure to fuse the sheet to the frame structure. In general, a fixture may include a first and second platen having a shaping portion and a rim portion positioned around the periphery of the platen, wherein the shaping portions are configured to hold the rib components of the frame structure in a loaded configuration with a decreased diameter.
摘要翻译： 这里描述的是用于将聚合物片材固定到框架结构的肋部件的系统和方法，其中肋部件在轮毂处接合以形成可膨胀和可折叠的植入物。 通常，该方法可以包括减小框架结构的直径的步骤; 将框架结构放置在组装夹具中，其中组装夹具被构造成将框架结构保持在具有减小的直径的加载构造中; 将聚合物片放置在组装夹具中; 并在压力下加热组件以将片材熔合到框架结构。 通常，固定装置可以包括第一和第二压板，该第一和第二压板具有成形部分和围绕压板的周边定位的边缘部分，其中成形部分构造成将框架结构的肋部件保持在加载构造中， 直径。
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公开(公告)号：US20140179993A1
公开(公告)日：2014-06-26
申请号：US14189856
申请日：2014-02-25
IPC分类号： A61M1/10
CPC分类号： A61F2/2487 , A61B17/0057 , A61B17/12022 , A61B17/12122 , A61B17/12172 , A61B2017/00243 , A61B2017/00575 , A61B2017/00579 , A61B2017/00592 , A61B2017/00597 , A61B2017/00615 , A61B2017/00632 , A61B2017/00867 , A61B2017/0649 , A61B2017/12095 , A61M1/10 , A61M1/1003 , A61M1/1008 , A61M1/1068 , A61M1/12 , A61M1/122 , A61M2205/32
摘要： A system for improving cardiac function is provided. A foldable and expandable frame having at least one anchoring formation is attached to an elongate manipulator and placed in a catheter tube while folded. The tube is inserted into a left ventricle of a heart where the frame is ejected from the tube and expands in the left ventricle. Movements of the elongate manipulator cause the anchor to penetrate the heart muscle and the elongate manipulator to release the frame. The installed frame minimizes the effects of an akinetic portion of the heart forming an aneurysmic bulge. Devices and methods are described herein which are directed to the treatment of a patient's heart having, or one which is susceptible to heart failure, to improve diastolic function.
摘要翻译： 提供了一种改善心脏功能的系统。 具有至少一个锚固结构的可折叠和可扩张的框架附接到细长的操纵器并且在折叠时放置在导管中。 将管插入心脏的左心室，其中框架从管中弹出并在左心室中扩张。 细长机械手的运动导致锚固体穿透心脏肌肉和细长操纵器以释放框架。 安装的框架最小化形成动脉瘤隆起的心脏的运动部分的影响。 本文描述了针对治疗患有心力衰竭或改善舒张功能的患者的心脏的装置和方法。
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公开(公告)号：US20170290664A1
公开(公告)日：2017-10-12
申请号：US15630601
申请日：2017-06-22
CPC分类号： A61F2/2487 , A61B17/0057 , A61B17/12022 , A61B17/12122 , A61B17/12172 , A61B2017/00243 , A61B2017/00575 , A61B2017/00579 , A61B2017/00592 , A61B2017/00597 , A61B2017/00615 , A61B2017/00632 , A61B2017/00867 , A61B2017/0649 , A61B2017/12095 , A61M1/10 , A61M1/1003 , A61M1/1008 , A61M1/1068 , A61M1/12 , A61M1/122 , A61M2205/32
摘要： A system for improving cardiac function is provided. A foldable and expandable frame having at least one anchoring formation is attached to an elongate manipulator and placed in a catheter tube while folded. The tube is inserted into a left ventricle of a heart where the frame is ejected from the tube and expands in the left ventricle. Movements of the elongate manipulator cause the anchor to penetrate the heart muscle and the elongate manipulator to release the frame. The installed frame minimizes the effects of an akinetic portion of the heart forming an aneurysmic bulge. Devices and methods are described herein which are directed to the treatment of a patient's heart having, or one which is susceptible to heart failure, to improve diastolic function.
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