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公开(公告)号:US20220363640A1
公开(公告)日:2022-11-17
申请号:US17208964
申请日:2021-03-22
发明人: Guangyi WANG , Leonid BEIGELMAN , Anh TRUONG , Carmela NAPOLITANO , Daniele ANDREOTTI , Haiying HE , Karin Ann STEIN
IPC分类号: C07D213/40 , C07D409/04 , C07D495/14 , C07D401/04 , C07D413/04 , C07D417/04 , C07D239/34 , C07D471/04 , C07D213/65 , C07D401/12 , C07D491/048 , C07D233/64 , C07D409/14 , C07D417/06 , C07D413/12 , C07D413/06 , C07D401/06 , C07D405/12 , C07D417/12 , C07D207/273 , C07D491/052 , A61K31/4436 , A61K31/4418 , A61K31/4178 , A61K31/4439 , A61K31/4365 , A61K31/422 , A61K31/4196 , A61K31/427 , A61K31/505 , A61K31/437 , A61K45/06 , A61K31/4355 , A61K31/444 , A61K31/4709
摘要: Disclosed herein are new antiviral compounds, together with pharmaceutical compositions that include one or more antiviral compounds, and methods of synthesizing the same. Also disclosed herein are methods of ameliorating and/or treating a paramyxovirus viral infection with one or more small molecule compounds. Examples of paramyxovirus infection include an infection caused by human respiratory syncytial virus (RSV).
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公开(公告)号:US20220396581A1
公开(公告)日:2022-12-15
申请号:US17228573
申请日:2021-04-12
发明人: Guangyi WANG , Leonid BEIGELMAN , Anh TRUONG , Carmela NAPOLITANO , Daniele ANDREOTTI , Haiying HE
IPC分类号: C07D495/04 , A61K31/352 , A61K31/4196 , A61K31/4365 , C07C255/66 , C07D233/88 , C07D261/20 , C07D307/40 , C07D307/52 , C07D333/20 , C07D333/58 , A61K31/4025 , A61K31/404 , A61K31/427 , A61K31/4375 , A61K31/4725 , C07D213/50 , C07D233/64 , C07D333/68 , C07D401/12 , C07D409/06 , A61K31/343 , A61K31/382 , A61K31/426 , A61K31/4418 , A61K31/4545 , C07C251/84 , C07D207/335 , C07D215/12 , C07D215/42 , C07D233/61 , C07D401/04 , C07D409/14 , A61K31/277 , A61K31/407 , A61K31/423 , A61K31/4436 , A61K31/4439 , A61K31/496 , A61K31/497 , A61K31/506 , C07C243/34 , C07D209/20 , C07D209/86 , C07D233/38 , C07D233/60 , C07D277/64 , C07D307/81 , C07D405/10 , C07D417/04 , C07D417/12 , A61K31/165 , A61K31/40 , A61K31/4709 , C07C243/18 , C07D277/56 , C07D333/66 , C07D413/04 , C07D471/04 , C07D495/14 , A61K31/4427 , A61K31/5377 , C07D213/42 , C07D213/68 , C07D215/38 , C07D217/24 , C07D307/91 , C07D311/68 , C07D333/16 , C07D333/62 , C07D401/10 , C07D409/12 , A61K31/341 , A61K31/4164 , A61K31/428 , A61K31/444 , A61K31/4704 , A61K31/501 , A61K45/06 , C07C255/34 , C07D209/08 , C07D215/14 , C07D333/54 , C07D335/06 , C07D405/04 , C07D405/12 , C07D409/04 , C07D413/12 , C07D413/14 , A61K31/381 , A61K31/4155 , A61K31/47 , A61K31/538 , C07C251/80 , C07D209/14 , C07D213/65 , C07D333/50 , C07D333/76
摘要: Disclosed herein are new antiviral compounds, together with pharmaceutical compositions that include one or more antiviral compounds, and methods of synthesizing the same. Also disclosed herein are methods of ameliorating and/or treating a paramyxovirus viral infection with one or more small molecule compounds. Examples of paramyxovirus infection include an infection caused by human respiratory syncytial virus (RSV).
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