公开(公告)号：US20170037136A1

公开(公告)日：2017-02-09

申请号：US15228582

申请日：2016-08-04

Applicant: Janssen Biotech, Inc.

Inventor： Johan Fransson ,  Galina Obmolova ,  Anish Suri ,  Fang Teng ,  Alexey Teplyakov ,  Hong Zhou ,  Jocelyn Leu

IPC: C07K16/28 ,  G01N33/68 ,  C07K16/42 ,  A61K39/395 ,  A61K45/06

Abstract: The present invention relates to antagonistic antibodies specifically binding CD154, polynucleotides encoding the antibodies or fragments, and methods of making and using the foregoing.

Abstract translation: 本发明涉及特异性结合CD154的拮抗性抗体，编码抗体或片段的多核苷酸，以及制备和使用上述物质的方法。

公开(公告)号：US20200317794A1

公开(公告)日：2020-10-08

申请号：US16853786

申请日：2020-04-21

Applicant: Janssen Biotech, Inc.

Inventor： Johan Fransson ,  Galina Obmolova ,  Anish Suri ,  Fang Teng ,  Alexey Teplyakov ,  Hong Zhou ,  Jocelyn Leu

IPC: C07K16/28 ,  A61K45/06

Abstract: The present invention relates to antagonistic antibodies specifically binding CD154, polynucleotides encoding the antibodies or fragments, and methods of making and using the foregoing.

公开(公告)号：US10669343B2

公开(公告)日：2020-06-02

申请号：US15228582

申请日：2016-08-04

Applicant: Janssen Biotech, Inc.

Inventor： Johan Fransson ,  Galina Obmolova ,  Anish Suri ,  Fang Teng ,  Alexey Teplyakov ,  Hong Zhou ,  Jocelyn Leu

IPC: A61K39/395 ,  C07K16/28 ,  A61K45/06

Abstract: The present invention relates to antagonistic antibodies specifically binding CD154, polynucleotides encoding the antibodies or fragments, and methods of making and using the foregoing.

公开(公告)号：US11421037B2

公开(公告)日：2022-08-23

申请号：US16853786

申请日：2020-04-21

Applicant: Janssen Biotech, Inc.

Inventor： Johan Fransson ,  Galina Obmolova ,  Anish Suri ,  Fang Teng ,  Alexey Teplyakov ,  Hong Zhou ,  Jocelyn Leu

IPC: C07K16/28 ,  A61K45/06

Abstract: The present invention relates to antagonistic antibodies specifically binding CD154, polynucleotides encoding the antibodies or fragments, and methods of making and using the foregoing.