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1.
公开(公告)号:US20210403592A1
公开(公告)日:2021-12-30
申请号:US17329057
申请日:2021-05-24
发明人: Tahamtan Ahmadi , Tineke Casneuf , Henk Lokhorst , Tuna Mutis , Amy Sasser , Niels van de Donk
IPC分类号: C07K16/28 , C07K16/40 , A61K39/395 , A61K38/47 , A61K45/06 , A61K31/454 , A61K31/573
摘要: The present invention relates to methods of immunomodulation and treating patients having solid tumors with antibodies that specifically bind CD38.
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公开(公告)号:US20170107295A1
公开(公告)日:2017-04-20
申请号:US15386391
申请日:2016-12-21
IPC分类号: C07K16/28 , A61K39/395 , A61K31/203
CPC分类号: C07K16/2896 , A61K31/203 , A61K39/39558 , A61K2039/505 , A61P35/00 , C07K2317/34 , C07K2317/51 , C07K2317/56 , C07K2317/565 , C07K2317/732 , C07K2317/734 , C07K2317/92 , A61K2300/00
摘要: The present invention relates to combination therapies with anti-CD38 antibodies and all-trans retinoic acid.
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公开(公告)号:US20160067205A1
公开(公告)日:2016-03-10
申请号:US14847428
申请日:2015-09-08
IPC分类号: A61K31/203 , A61K39/395 , C07K16/40
CPC分类号: C07K16/2896 , A61K31/203 , A61K39/39558 , A61K2039/505 , A61P35/00 , C07K2317/34 , C07K2317/51 , C07K2317/56 , C07K2317/565 , C07K2317/732 , C07K2317/734 , C07K2317/92 , A61K2300/00
摘要: The present invention relates to combination therapies with anti-CD38 antibodies and all-trans retinoic acid.
摘要翻译: 本发明涉及与抗CD38抗体和全反式视黄酸的组合疗法。
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4.
公开(公告)号:US11021543B2
公开(公告)日:2021-06-01
申请号:US16162355
申请日:2018-10-16
发明人: Tahamtan Ahmadi , Tineke Casneuf , Henk Lokhorst , Tuna Mutis , Amy Sasser , Niels van de Donk
IPC分类号: C07K16/28 , A61K39/395 , C07K16/40 , A61K38/47 , A61K45/06 , A61K31/454 , A61K31/573 , A61K39/00
摘要: The present invention relates to methods of immunomodulation and treating patients having solid tumors with antibodies that specifically bind CD38.
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5.Immune Modulation and Treatment of Solid Tumors with Antibodies that Specifically Bind CD38 审中-公开
标题翻译: 用具体绑定CD38的抗体对实体肿瘤的免疫调节和治疗公开(公告)号:US20170044265A1
公开(公告)日:2017-02-16
申请号:US15340214
申请日:2016-11-01
发明人: Tahamtan Ahmadi , Tineke Casneuf , Henk Lokhorst , Tuna Mutis , Amy Sasser , Niels van de Donk
IPC分类号: C07K16/28 , A61K38/47 , A61K39/395 , C07K16/40 , C07K16/30
CPC分类号: C07K16/2896 , A61K31/454 , A61K31/573 , A61K38/47 , A61K39/39558 , A61K45/06 , A61K2039/505 , A61K2039/545 , A61K2039/55 , C07K16/40 , C07K2317/56 , C07K2317/565 , C12Y204/99 , C12Y302/01035 , A61K2300/00
摘要: The present invention relates to methods of immunomodulation and treating patients having solid tumors with antibodies that specifically bind CD38.
摘要翻译: 本发明涉及用具有特异性结合CD38的抗体免疫调节和治疗具有实体瘤患者的方法。
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6.Immune Modulation and Treatment of Solid Tumors with Antibodies that Specifically Bind CD38 审中-公开
标题翻译: 用具体绑定CD38的抗体对实体肿瘤的免疫调节和治疗公开(公告)号:US20160376373A1
公开(公告)日:2016-12-29
申请号:US15191808
申请日:2016-06-24
发明人: Tahamtan Ahmadi , Tineke Casneuf , Henk Lokhorst , Tuna Mutis , Amy Sasser
IPC分类号: C07K16/28 , A61K45/06 , C07K16/40 , A61K39/395
CPC分类号: C07K16/2896 , A61K39/39558 , A61K45/06 , A61K2039/505 , A61K2039/507 , A61K2039/545 , A61P35/00 , A61P37/04 , C07K16/2803 , C07K16/2818 , C07K16/2827 , C07K16/40 , C07K2317/31 , C07K2317/34 , C07K2317/56 , C07K2317/565 , C07K2317/70 , C07K2317/732 , C07K2317/76
摘要: The present invention relates to methods of immunomodulation and treating patients having solid tumors with antibodies that specifically bind CD38.
摘要翻译: 本发明涉及用具有特异性结合CD38的抗体免疫调节和治疗具有实体瘤患者的方法。
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7.Combination therapies for heme malignancies with Anti-CD38 antibodies and survivin inhibitors 审中-公开
标题翻译: 用抗CD38抗体和存活蛋白抑制剂组合治疗血红素恶性肿瘤公开(公告)号:US20160367663A1
公开(公告)日:2016-12-22
申请号:US15189577
申请日:2016-06-22
发明人: Parul Doshi , Henk M. Lokhorst , Tuna Mutis
IPC分类号: A61K39/395 , A61K9/00 , A61K38/47 , A61K31/497
摘要: The present invention relates to combination therapies for heme malignancies with anti-CD38 antibodies and survivin inhibitors.
摘要翻译: 本发明涉及用抗CD38抗体和存活蛋白抑制剂的血红素恶性肿瘤的组合疗法。
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8.
公开(公告)号:US10668149B2
公开(公告)日:2020-06-02
申请号:US15189577
申请日:2016-06-22
发明人: Parul Doshi , Henk M. Lokhorst , Tuna Mutis
IPC分类号: A61K39/395 , A61K9/00 , C07K16/28 , A61K31/497 , A61K38/47 , A61K39/00
摘要: The present invention relates to combination therapies for heme malignancies with anti-CD38 antibodies and survivin inhibitors.
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公开(公告)号:US10604580B2
公开(公告)日:2020-03-31
申请号:US15386391
申请日:2016-12-21
IPC分类号: A61K39/395 , C07K16/28 , A61K31/203 , A61P35/00 , A61K39/00
摘要: The present invention relates to combination therapies with anti-CD38 antibodies and all-trans retinoic acid.
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10.
公开(公告)号:US20190144557A1
公开(公告)日:2019-05-16
申请号:US16162355
申请日:2018-10-16
发明人: Tahamtan Ahmadi , Tineke Casneuf , Henk Lokhorst , Tuna Mutis , Amy Sasser , Niels van de Donk
IPC分类号: C07K16/28 , A61K39/395 , A61K45/06 , A61K31/454 , A61K31/573 , A61K38/47 , C07K16/40
摘要: The present invention relates to methods of immunomodulation and treating patients having solid tumors with antibodies that specifically bind CD38.
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