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公开(公告)号：US06238882B1
公开(公告)日：2001-05-29
申请号：US09104068
申请日：1998-06-24
申请人： Jason Craig Fedon , Deborah D Jaworski , Howard Kallender , Anna Lisa Lenox , Leslie Marie Palmer , Min Wang
发明人： Jason Craig Fedon , Deborah D Jaworski , Howard Kallender , Anna Lisa Lenox , Leslie Marie Palmer , Min Wang
IPC分类号： C12P2106
CPC分类号： C07K14/3156 , A61K38/00 , A61K48/00 , C07K2319/00
摘要： The invention provides gidA1 polypeptides and polynucleotides encoding gidA1 polypeptides and methods for producing such polypeptides by recombinant techniques. Also provided are methods for utilizing gidA1 polypeptides to screen for antibacterial compounds.
摘要翻译： 本发明提供gidA1多肽和编码gidA1多肽的多核苷酸以及通过重组技术产生此类多肽的方法。 还提供了利用gidA1多肽筛选抗菌化合物的方法。
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公开(公告)号：US5891672A
公开(公告)日：1999-04-06
申请号：US977554
申请日：1997-11-25
申请人： Min Wang , Judith M Ward , Richard Lloyd Warren , Richard Oakley Nicholas , Leslie Marie Palmer , Julie M Pratt , David Justin Charles Knowles , Michael Arthur Lonetto , Jeffrey Mooney , Michael Terence Black , Martin Karl Russell Burnham , Christine Debouck , Jason Craig Fedon , John Edward Hodgson , Deborah Dee Jaworski , Raymond Winfield Reichard , Martin Rosenberg , Christopher Michael Traini , Yi Yi Zhong
发明人： Min Wang , Judith M Ward , Richard Lloyd Warren , Richard Oakley Nicholas , Leslie Marie Palmer , Julie M Pratt , David Justin Charles Knowles , Michael Arthur Lonetto , Jeffrey Mooney , Michael Terence Black , Martin Karl Russell Burnham , Christine Debouck , Jason Craig Fedon , John Edward Hodgson , Deborah Dee Jaworski , Raymond Winfield Reichard , Martin Rosenberg , Christopher Michael Traini , Yi Yi Zhong
IPC分类号： G01N33/53 , A61K31/7088 , A61K38/00 , A61K38/43 , A61K39/085 , A61K39/395 , A61K48/00 , A61P1/00 , A61P9/00 , A61P11/00 , A61P11/02 , A61P13/02 , A61P13/12 , A61P17/00 , A61P17/02 , A61P19/00 , A61P25/00 , A61P27/02 , A61P27/16 , A61P43/00 , C07H21/04 , C07K14/31 , C07K16/12 , C12N1/15 , C12N1/19 , C12N1/21 , C12N5/10 , C12N9/78 , C12N9/86 , C12N15/09 , C12N15/31 , C12P21/02 , C12R1/445 , C07H21/00 , C12N15/63
CPC分类号： C12Y305/04025 , C12N9/78 , C07K2319/00
摘要： The invention provides ribA polypeptides and polynucleotides encoding ribA polypeptides and methods for producing such polypeptides by recombinant techniques. Also provided are methods for utilizing ribA polypeptides to screen for antibacterial compounds.
摘要翻译： 本发明提供ribA多肽和编码ribA多肽的多核苷酸以及通过重组技术产生此类多肽的方法。 还提供了利用ribA多肽筛选抗菌化合物的方法。
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公开(公告)号：US06326462B1
公开(公告)日：2001-12-04
申请号：US09491916
申请日：2000-01-27
申请人： Christine Debouck , Jason Craig Fedon , Deborah Dee Jaworski , Jeffrey Mooney , Leslie Marie Palmer , Christopher Michael Traini , Min Wang , Richard Lloyd Warren , Yi Yi Zhong
发明人： Christine Debouck , Jason Craig Fedon , Deborah Dee Jaworski , Jeffrey Mooney , Leslie Marie Palmer , Christopher Michael Traini , Min Wang , Richard Lloyd Warren , Yi Yi Zhong
IPC分类号： A61K3902
CPC分类号： C12N9/1085 , A61K38/00
摘要： The invention provides ribH polypeptides and polynucleotides encoding ribH polypeptides and methods for producing such polypeptides by recombinant techniques. Also provided are methods for utilizing ribH polypeptides to screen for antibacterial compounds.
摘要翻译： 本发明提供ribH多肽和编码ribH多肽的多核苷酸以及通过重组技术产生此类多肽的方法。 还提供了利用ribH多肽筛选抗菌化合物的方法。
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公开(公告)号：US06280971B1
公开(公告)日：2001-08-28
申请号：US09227806
申请日：1999-01-11
申请人： Min Wang , Judith M Ward , Richard Lloyd Warren , Richard Oakley Nicholas , Leslie Marie Palmer , Julie M Pratt , David Justin Charles Knowles , Michael Arthur Lonetto , Jeffrey Mooney , Michael Terence Black , Martin Karl Russell Burnham , Christine Debouck , Jason Craig Fedon , John Edward Hodgson , Deborah Dee Jaworski , Raymond Winfield Reichard , Martin Rosenberg , Christopher Michael Traini , Yi Y Zhong
发明人： Min Wang , Judith M Ward , Richard Lloyd Warren , Richard Oakley Nicholas , Leslie Marie Palmer , Julie M Pratt , David Justin Charles Knowles , Michael Arthur Lonetto , Jeffrey Mooney , Michael Terence Black , Martin Karl Russell Burnham , Christine Debouck , Jason Craig Fedon , John Edward Hodgson , Deborah Dee Jaworski , Raymond Winfield Reichard , Martin Rosenberg , Christopher Michael Traini , Yi Y Zhong
IPC分类号： C12N1231
CPC分类号： C12Y305/04025 , C07K2319/00 , C12N9/78
摘要： The invention provides ribA polypeptides and polynucleotides encoding ribA polypeptides and methods for producing such polypeptides by recombinant techniques. Also provided are methods for utilizing ribA polypeptides to screen for antibacterial compounds.
摘要翻译： 本发明提供ribA多肽和编码ribA多肽的多核苷酸以及通过重组技术产生此类多肽的方法。 还提供了利用ribA多肽筛选抗菌化合物的方法。
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公开(公告)号：US06335424B1
公开(公告)日：2002-01-01
申请号：US08979616
申请日：1997-11-25
申请人： Michael Terence Black , Christine Debouck , Jason Craig Fedon , John Edward Hodgson , Deborah Dee Jaworski , David Justin Charles Knowles , Anna Lisa Kosmatka , Jeffrey Mooney , Richard Oakley Nicholas , Leslie Marie Palmer , Lisa Kathleen Shilling , Robert King Stodola , Min Wang , Richard Lloyd Warren , Yi Yi Zhong
发明人： Michael Terence Black , Christine Debouck , Jason Craig Fedon , John Edward Hodgson , Deborah Dee Jaworski , David Justin Charles Knowles , Anna Lisa Kosmatka , Jeffrey Mooney , Richard Oakley Nicholas , Leslie Marie Palmer , Lisa Kathleen Shilling , Robert King Stodola , Min Wang , Richard Lloyd Warren , Yi Yi Zhong
IPC分类号： A61K3902
CPC分类号： C07K14/3156 , A61K38/00 , A61K39/00 , C12N9/1205 , C12N9/78 , C12N9/80 , C12N9/90 , C12N15/52 , C12Y207/01002
摘要： The invention provides ribG polypeptides and polynucleotides encoding ribG polypeptides and methods for producing such polypeptides by recombinant techniques. Also provided are methods for utilizing ribG polypeptides to screen for antibacterial compounds.
摘要翻译： 本发明提供ribG多肽和编码ribG多肽的多核苷酸以及通过重组技术产生此类多肽的方法。 还提供了利用ribG多肽筛选抗菌化合物的方法。
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公开(公告)号：US06171598B2
公开(公告)日：2001-01-09
申请号：US09225967
申请日：1999-01-06
申请人： Min Wang , Judith M Ward , Richard Lloyd Warren , Richard Oakley Nicholas , Leslie Marie Palmer , Julie M Pratt , David Justin Charles Knowles , Michael Arthur Lonetto , Jeffrey Mooney , Michael Terence Black , Martin Karl Russell Burnham , Christine Debouck , Jason Craig Fedon , John Edward Hodgson , Deborah Dee Jaworski , Raymond Winfield Reichard , Martin Rosenberg , Christopher Michael Traini , Yi Yi Zhong
发明人： Min Wang , Judith M Ward , Richard Lloyd Warren , Richard Oakley Nicholas , Leslie Marie Palmer , Julie M Pratt , David Justin Charles Knowles , Michael Arthur Lonetto , Jeffrey Mooney , Michael Terence Black , Martin Karl Russell Burnham , Christine Debouck , Jason Craig Fedon , John Edward Hodgson , Deborah Dee Jaworski , Raymond Winfield Reichard , Martin Rosenberg , Christopher Michael Traini , Yi Yi Zhong
IPC分类号： A61K3850
CPC分类号： C12Y305/04025 , C07K2319/00 , C12N9/78
摘要： The invention provides ribA polypeptides and polynucleotides encoding ribA polypeptides and methods for producing such polypeptides by recombinant techniques. Also provided are methods for utilizing ribA polypeptides to screen for antibacterial compounds.
摘要翻译： 本发明提供ribA多肽和编码ribA多肽的多核苷酸以及通过重组技术产生此类多肽的方法。 还提供了利用ribA多肽筛选抗菌化合物的方法。
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公开(公告)号：US06300119B1
公开(公告)日：2001-10-09
申请号：US09273142
申请日：1999-03-19
IPC分类号： C12N120
摘要： The invention provides gluS polypeptides and DNA (RNA) encoding gluS polypetides and methods for producing such polypeptides by recombinant techniques. Also provided are methods for utilizing gluS polypeptides to screen for antibacterial compounds.
摘要翻译： 本发明提供gluS多肽和编码gluS多肽的DNA（RNA），以及通过重组技术产生此类多肽的方法。 还提供了利用gluS多肽筛选抗菌化合物的方法。
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公开(公告)号：US06204014B1
公开(公告)日：2001-03-20
申请号：US09191879
申请日：1998-11-13
申请人： Alison F Chalker , David J Holmes , Karen A Ingraham , Deborah D Jaworski , Anna L Lenox , Earl W May , Marie J Mazzulla , Jennifer Ray , Min Wang , Richard L Warren, Jr.
发明人： Alison F Chalker , David J Holmes , Karen A Ingraham , Deborah D Jaworski , Anna L Lenox , Earl W May , Marie J Mazzulla , Jennifer Ray , Min Wang , Richard L Warren, Jr.
IPC分类号： C12P2106
CPC分类号： C12N9/90 , A61K38/00 , C07K2319/00
摘要： The invention provides DnaB polypeptides and polynucleotides encoding DnaB polypeptides and methods for producing such polypeptides by recombinant techniques. Also provided are methods for utilizing DnaB polypeptides to screen for anibacterial compounds.
摘要翻译： 本发明提供DnaB多肽和编码DnaB多肽的多核苷酸以及通过重组技术产生此类多肽的方法。 还提供了利用DnaB多肽来筛选细菌化合物的方法。
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9.发明授权
公开(公告)号：US5976840A
公开(公告)日：1999-11-02
申请号：US962203
申请日：1997-10-31
IPC分类号： A61K39/00 , C07H21/04 , C07K1/00 , C12N1/20 , C12N5/00 , C12N9/00 , C12N9/10 , C12N15/00 , C12P21/06 , C12P21/04
摘要： The invention provides gluS polypeptides and DNA (RNA) encoding gluS polypetides and methods for producing such polypeptides by recombinant techniques. Also provided are methods for utilizing gluS polypeptides to screen for antibacterial compounds.
摘要翻译： 本发明提供gluS多肽和编码gluS多肽的DNA（RNA），以及通过重组技术产生此类多肽的方法。 还提供了利用gluS多肽筛选抗菌化合物的方法。
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公开(公告)号：US6165760A
公开(公告)日：2000-12-26
申请号：US282125
申请日：1999-03-31
摘要： The invention provides gluS polypeptides and DNA (RNA) encoding gluS polypetides and methods for producing such polypeptides by recombinant techniques. Also provided are methods for utilizing gluS polypeptides to screen for antibacterial compounds.
摘要翻译： 本发明提供gluS多肽和编码gluS多肽的DNA（RNA），以及通过重组技术产生此类多肽的方法。 还提供了利用gluS多肽筛选抗菌化合物的方法。
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