公开(公告)号：US20080208324A1

公开(公告)日：2008-08-28

申请号：US12033935

申请日：2008-02-20

申请人： Jason I. Glithero ,  Livyn O. Okorocha ,  James G. Tappel ,  Eric E. Bielefeld ,  Michael W. Goldenbogen ,  Chadd R. Tyler ,  Todd A. Hall ,  Stephen C. Robinson ,  Greg R. Furnish

发明人： Jason I. Glithero ,  Livyn O. Okorocha ,  James G. Tappel ,  Eric E. Bielefeld ,  Michael W. Goldenbogen ,  Chadd R. Tyler ,  Todd A. Hall ,  Stephen C. Robinson ,  Greg R. Furnish

IPC分类号： A61F2/06 ,  A61B17/08

CPC分类号： A61B17/122 ,  A61B17/00491 ,  A61B17/0643 ,  A61B17/12122 ,  A61B17/12136 ,  A61B17/12186 ,  A61B17/1227 ,  A61B17/1327 ,  A61B2017/00243 ,  A61B2017/0641

摘要： Methods and apparatus for occluding an anatomical structure including a device having at least first and second clamp portions adapted to cooperate to move from an open position adjacent an anatomical structure to a closed position engaging and occluding the anatomical structure. A system for delivery of a fluid to affect occlusion of an anatomical structure is provided, as well as an applicator for deploying occlusion devices having different sizes.

摘要翻译： 用于闭塞解剖结构的方法和装置，包括具有至少第一和第二夹持部分的装置，所述装置适于协调从邻近解剖结构的打开位置移动到接合和阻塞解剖结构的闭合位置。 提供了一种用于输送流体以影响解剖结构的闭塞的系统，以及用于部署具有不同尺寸的闭塞装置的施用器。

公开(公告)号：US20140142690A1

公开(公告)日：2014-05-22

申请号：US13982612

申请日：2012-01-31

申请人： Melinda K. Kovach ,  Susan E. Clegg ,  Benjamin E. Morris ,  Gregory R. Furnish ,  Eric E. Bielefeld ,  Simon McKnight Furnish

发明人： Melinda K. Kovach ,  Susan E. Clegg ,  Benjamin E. Morris ,  Gregory R. Furnish ,  Eric E. Bielefeld ,  Simon McKnight Furnish

IPC分类号： A61F2/24

CPC分类号： A61F2/2466 ,  A61B5/1076 ,  A61F2/2445 ,  A61F2/2448 ,  A61F2/2496 ,  A61F2250/001 ,  A61F2250/006 ,  A61F2250/0065 ,  A61F2250/0089 ,  A61F2250/0097 ,  B25B15/02 ,  B25B23/142 ,  B25G1/046 ,  B25G3/18

摘要： An adjustable prosthetic anatomical holder system may include an adjustable annuloplasty ring, a ring holder, and a positioning handle. The adjustable annuloplasty ring holder facilitates placement and adjustment of the annuloplasty ring during a cardiac surgical procedure. An optional positioning handle holds the adjustable annuloplasty ring during placement and suturing of the ring. The ring holder is constructed from two members that are slidably fit together in telescopic arrangement to accommodate adjustment of the ring size.

摘要翻译： 可调节的假体解剖支架系统可以包括可调节瓣环成形术环，环保持器和定位手柄。 可调节瓣环成形术环座在心脏外科手术过程中有利于瓣环成形术环的放置和调整。 可选的定位手柄在环的放置和缝合期间保持可调节瓣环成形术环。 环形支架由两个构件构成，这两个构件可伸缩地可滑动地配合在一起，以适应环尺寸的调节。

公开(公告)号：US09622860B2

公开(公告)日：2017-04-18

申请号：US13982826

申请日：2012-01-31

申请人： Eric E. Bielefeld ,  Gregory R. Furnish ,  Christopher Bethards

发明人： Eric E. Bielefeld ,  Gregory R. Furnish ,  Christopher Bethards

IPC分类号： A61F2/24 ,  B25G3/18 ,  B25B15/02 ,  B25B23/00 ,  B25G1/04

CPC分类号： A61F2/2427 ,  A61F2/2466 ,  A61F2250/001 ,  B25B15/02 ,  B25B23/0064 ,  B25G1/04 ,  B25G3/18

摘要： An adjustment tool enables manipulation of a prosthetic anatomical device such as an annuloplasty ring. The tool includes a compression member which is operative for retarding rotation of the adjustment shaft to preclude inadvertent rotation thereof during use of the tool by the surgeon. A locking device is associated with the adjustment tool to enable the releasable attachment of the tool to the anatomical device during its adjustment by manipulation of the tool. The locking device is oriented into operative and inoperative positions by the engagement and disengagement of locking elements. A scale may be provided on the adjustment tool to assist a surgeon in determining the size or amount of adjustment to the size of the anatomical device during its adjustment.

公开(公告)号：US20140088691A1

公开(公告)日：2014-03-27

申请号：US13982531

申请日：2012-01-31

申请人： Eric E. Bielefeld

发明人： Eric E. Bielefeld

IPC分类号： A61F2/24

CPC分类号： A61F2/2466 ,  A61F2/2445 ,  A61F2/2496 ,  A61F2002/30395 ,  A61F2250/001 ,  B25B15/02 ,  B25B23/0064 ,  B25G1/046 ,  B25G3/18

摘要： An adjustment tool enables manipulation of a prosthetic anatomical device such as an annuloplasty ring. The tool includes a compression member which is operative for retarding rotation of the adjustment shaft to preclude inadvertent rotation thereof during use of the tool by the surgeon. A locking device is associated with the adjustment tool to enable the releasable attachment of the tool to the anatomical device during its adjustment by manipulation of the tool. The locking device is oriented into operative and inoperative positions by the engagement and disengagement of locking elements. A scale may be provided on the adjustment tool to assist a surgeon in determining the size or amount of adjustment to the size of the anatomical device during its adjustment.

摘要翻译： 调节工具能够操作诸如瓣环成形术的假体解剖装置。 该工具包括压缩构件，该压缩构件用于在外科医生使用该工具期间阻止调节轴的旋转以防止其意外旋转。 锁定装置与调节工具相关联，以便在通过操纵工具进行调节期间使得工具能够可释放地附接到解剖装置。 通过锁定元件的接合和分离，锁定装置被定位成操作和不工作的位置。 可以在调节工具上提供刻度，以帮助外科医生确定在其调节期间对解剖装置的尺寸的调整的尺寸或量。

公开(公告)号：US09872770B2

公开(公告)日：2018-01-23

申请号：US14237993

申请日：2012-07-19

申请人： Eric E. Bielefeld

发明人： Eric E. Bielefeld

IPC分类号： A61F2/24 ,  A61B17/068 ,  A61B17/10 ,  A61B17/00 ,  A61B17/064 ,  A61B17/11 ,  A61B17/29 ,  A61B17/34 ,  A61B90/00

CPC分类号： A61F2/2487 ,  A61B17/068 ,  A61B17/10 ,  A61B2017/00243 ,  A61B2017/00349 ,  A61B2017/00783 ,  A61B2017/0649 ,  A61B2017/1103 ,  A61B2017/2932 ,  A61B2017/3488 ,  A61B2090/3925 ,  A61F2/2442

摘要： A device and method for repairing a mitral valve leaflet 2, 3. The device 10 includes a body 16 having an annular wall 18 and at least one aperture 22 through the annular wall 18. A deployment assembly 24 mounted on the body includes at least one grasping wire 28 arranged for sliding movement in the aperture 22. Movement of the deployment assembly 24 to a deployed position relative to the body causes a free end of the grasping wire 28 to project out from the annular wall 18 through the aperture 22, and movement of the deployment assembly to a retracted position relative to the body causes the free end of the grasping wire 28 to not project out from the annular wall 18. In the deployed position, the grasping wire 28 may grasp and gather tissue of the leaflet 2,3.

公开(公告)号：US09763784B2

公开(公告)日：2017-09-19

申请号：US13982531

申请日：2012-01-31

申请人： Eric E. Bielefeld

发明人： Eric E. Bielefeld

IPC分类号： A61F2/24 ,  B25B15/02 ,  B25G1/04 ,  B25G3/18 ,  B25B23/00

CPC分类号： A61F2/2466 ,  A61F2/2445 ,  A61F2/2496 ,  A61F2002/30395 ,  A61F2250/001 ,  B25B15/02 ,  B25B23/0064 ,  B25G1/046 ,  B25G3/18

摘要： An adjustment tool enables manipulation of a prosthetic anatomical device such as an annuloplasty ring. The tool includes a compression member which is operative for retarding rotation of the adjustment shaft to preclude inadvertent rotation thereof during use of the tool by the surgeon. A locking device is associated with the adjustment tool to enable the releasable attachment of the tool to the anatomical device during its adjustment by manipulation of the tool. The locking device is oriented into operative and inoperative positions by the engagement and disengagement of locking elements. A scale may be provided on the adjustment tool to assist a surgeon in determining the size or amount of adjustment to the size of the anatomical device during its adjustment.

公开(公告)号：US09532874B2

公开(公告)日：2017-01-03

申请号：US14127575

申请日：2012-06-12

申请人： Mark Griffin ,  Benjamin E. Morris ,  Eric E. Bielefeld ,  Gregory R. Furnish ,  Wayne Allen Johnson

发明人： Mark Griffin ,  Benjamin E. Morris ,  Eric E. Bielefeld ,  Gregory R. Furnish ,  Wayne Allen Johnson

IPC分类号： A61F2/24 ,  A61B17/064 ,  A61B17/068 ,  A61B17/00 ,  A61B17/29

CPC分类号： A61F2/2487 ,  A61B17/064 ,  A61B17/068 ,  A61B17/29 ,  A61B2017/00243 ,  A61B2017/00429 ,  A61B2017/0647 ,  A61B2017/2926

摘要： A device 10 for repairing mitral valve leaflets 2, 3 includes a jaw mechanism 15 that may be positioned adjacent a mitral valve leaflet 2, 3. The jaw mechanism 15 may move between an open position and a closed position by pivoting a first jaw relative 16 to a second jaw 18. The first jaw 16 may include a rivet 28 that may move from a stored position to an application position projecting away from the first jaw 16 when the jaw mechanism 15 is moved from the closed to the open position. Closing the jaws 16, 18 about a valve leaflet 2, 3 causes the rivet 28 to pierce the leaflet. The jaw mechanism 15 may then be rotated to wind the leaflet 2, 3 thereabout and again pierce the leaflet. The rivet 28 may then be released from the jaw mechanism 25 and the device 10 removed from the patient.

摘要翻译： 用于修复二尖瓣小叶2,3的装置10包括钳口机构15，其可以邻近二尖瓣小叶2,3定位。钳口机构15可以通过使第一钳口相对于16枢转而在打开位置和关闭位置之间移动 第二钳口16可以包括铆钉28，当夹爪机构15从关闭位置移动到打开位置时，铆钉28可以从存储位置移动到远离第一钳口16伸出的施加位置。 关闭阀瓣16,18关于阀传单2,3使得铆钉28刺穿传单。 然后可以将钳口机构15旋转以在其周围缠绕小叶2,3，并再次刺穿小叶。 铆钉28然后可以从钳口机构25释放，并且装置10从患者身上移开。

公开(公告)号：US20140128970A1

公开(公告)日：2014-05-08

申请号：US14127575

申请日：2012-06-12

申请人： Mark Griffin ,  Benjamin E. Morris ,  Eric E. Bielefeld ,  Gregory R. Furnish ,  Wayne Allen Johnson

发明人： Mark Griffin ,  Benjamin E. Morris ,  Eric E. Bielefeld ,  Gregory R. Furnish ,  Wayne Allen Johnson

IPC分类号： A61F2/24

CPC分类号： A61F2/2487 ,  A61B17/064 ,  A61B17/068 ,  A61B17/29 ,  A61B2017/00243 ,  A61B2017/00429 ,  A61B2017/0647 ,  A61B2017/2926

摘要： A device 10 for repairing mitral valve leaflets 2, 3 includes a jaw mechanism 15 that may be positioned adjacent a mitral valve leaflet 2, 3. The jaw mechanism 15 may move between an open position and a closed position by pivoting a first jaw relative 16 to a second jaw 18. The first jaw 16 may include a rivet 28 that may move from a stored position to an application position projecting away from the first jaw 16 when the jaw mechanism 15 is moved from the closed to the open position. Closing the jaws 16, 18 about a valve leaflet 2, 3 causes the rivet 28 to pierce the leaflet. The jaw mechanism 15 may then be rotated to wind the leaflet 2, 3 thereabout and again pierce the leaflet. The rivet 28 may then be released from the jaw mechanism 25 and the device 10 removed from the patient.

摘要翻译： 用于修复二尖瓣小叶2,3的装置10包括钳口机构15，其可以邻近二尖瓣小叶2,3定位。钳口机构15可以通过使第一钳口相对于16枢转而在打开位置和关闭位置之间移动 第二钳口16可以包括铆钉28，当夹爪机构15从关闭位置移动到打开位置时，铆钉28可以从存储位置移动到远离第一钳口16伸出的施加位置。 关闭阀瓣16,18关于阀传单2,3使得铆钉28刺穿传单。 然后可以将钳口机构15旋转以在其周围缠绕小叶2,3，并再次刺穿小叶。 铆钉28然后可以从钳口机构25释放，并且装置10从患者身上移开。

公开(公告)号：US20090301480A1

公开(公告)日：2009-12-10

申请号：US12135880

申请日：2008-06-09

申请人： Mamdouh Elsakka ,  Christine T. Kearney ,  Ho-Kin Ng ,  John Edrington ,  Keith Wells ,  Greg Furnish ,  Eric E. Bielefeld

发明人： Mamdouh Elsakka ,  Christine T. Kearney ,  Ho-Kin Ng ,  John Edrington ,  Keith Wells ,  Greg Furnish ,  Eric E. Bielefeld

IPC分类号： A61M16/00

CPC分类号： A61M25/0068 ,  A61B10/0045 ,  A61M1/0003 ,  A61M1/007 ,  A61M16/0463 ,  A61M25/001 ,  A61M25/0074 ,  A61M25/04 ,  A61M2025/0004 ,  A61M2025/0079 ,  A61M2025/0081 ,  A61M2025/0175 ,  A61M2025/1052 ,  A61M2210/1035

摘要： A bronchoalveolar lavage instillation/aspiration system which includes (i) a needleless bronchoalveolar lavage instillation/aspiration device with a barrel member including a barrel lumen having a distal aperture and a self-sealing member configured for maintaining a fluid-disruptable, resealable barrier to the distal aperture; and (ii) a catheter assembly configured to provide a patent path of fluid communication between the instillation/aspiration device and a patient bronchial passage, where the catheter includes a wedging structure configured to engage a patient bronchial passage. In another aspect, embodiments of the present invention may include one or more methods of making and using a system or component described herein.

摘要翻译： 支气管肺泡灌洗滴注/抽吸系统，其包括（i）无针支气管肺泡灌洗滴注/抽吸装置，其具有筒体构件，所述筒体构件包括具有远端孔的管腔，以及自密封构件，所述自密封构件构造成用于将流体破裂， 远端孔径 和（ii）导管组件，其构造成提供滴注/抽吸装置与患者支气管通道之间的流体连通的专利路径，其中导管包括构造成接合患者支气管通道的楔入结构。 在另一方面，本发明的实施例可以包括制造和使用本文所述的系统或组件的一种或多种方法。

公开(公告)号：US10028834B2

公开(公告)日：2018-07-24

申请号：US13982612

申请日：2012-01-31

申请人： Melinda K. Kovach ,  Susan E. Clegg ,  Benjamin E. Morris ,  Gregory R. Furnish ,  Eric E. Bielefeld ,  Simon McKnight Furnish

发明人： Melinda K. Kovach ,  Susan E. Clegg ,  Benjamin E. Morris ,  Gregory R. Furnish ,  Eric E. Bielefeld ,  Simon McKnight Furnish

IPC分类号： A61F2/24 ,  B25G1/04 ,  B25G3/18 ,  B25B15/02 ,  B25B23/142 ,  A61B5/107

摘要： An adjustable prosthetic anatomical holder system may include an adjustable annuloplasty ring, a ring holder, and a positioning handle. The adjustable annuloplasty ring holder facilitates placement and adjustment of the annuloplasty ring during a cardiac surgical procedure. An optional positioning handle holds the adjustable annuloplasty ring during placement and suturing of the ring. The ring holder is constructed from two members that are slidably fit together in telescopic arrangement to accommodate adjustment of the ring size.