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公开(公告)号：US20110182770A1
公开(公告)日：2011-07-28
申请号：US13063945
申请日：2009-10-12
申请人： Sailaja Chandrapati , Jeffrey C. Pederson , Heather M. Webb , Jeffrey D. Smith , Kurt J. Halverson , Bryan S. Behun , Peter D. Ludowise
发明人： Sailaja Chandrapati , Jeffrey C. Pederson , Heather M. Webb , Jeffrey D. Smith , Kurt J. Halverson , Bryan S. Behun , Peter D. Ludowise
IPC分类号： A61L2/18
摘要： A biological sterilization indicator, system, and methods of determining the effectiveness of a sterilization process. The biological sterilization indicator can include a locus of spores, a reservoir containing a liquid, and a sterilant path positioned to provide fluid communication between ambience and the locus of spores. The reservoir can have a closed state in which the reservoir is not in fluid communication with the locus of spores and an open state in which the reservoir is in fluid communication with the locus of spores. The biological sterilization indicator system can include the biological sterilization indicator and a detection device adapted to be coupled to the biological sterilization indicator. In some embodiments, the method can include assaying the spores for a detectable change in a characteristic, and detecting substantially all of the detectable change.
摘要翻译： 一种生物灭菌指标，系统和确定灭菌过程有效性的方法。 生物灭菌指示剂可以包括孢子的位点，含有液体的储存器和定位成在气氛和孢子的位置之间提供流体连通的消毒剂通道。 储存器可以具有闭合状态，其中储存器不与孢子的轨迹流体连通，并且储存器与孢子的轨迹流体连通的打开状态。 生物灭菌指示器系统可以包括生物灭菌指示器和适于联接到生物灭菌指示器的检测装置。 在一些实施方案中，该方法可以包括测定孢子以获得特征的可检测变化，并且检测基本上所有可检测的变化。
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公开(公告)号：US09067205B2
公开(公告)日：2015-06-30
申请号：US13474779
申请日：2012-05-18
CPC分类号： B01L3/502738 , B01L2200/0684 , B01L2200/0689 , B01L2200/16 , B01L2300/0803 , B01L2300/087 , B01L2300/0887 , B01L2400/0406 , B01L2400/0409 , B01L2400/0677 , B01L2400/0688
摘要： A system and method for valving on a sample processing device. The system can include a valve chamber, a process chamber, and a valve septum located between the valve chamber and the process chamber. The system can further include a fluid pathway in fluid communication with an inlet of the valve chamber, wherein the fluid pathway is configured to inhibit a liquid from entering the valve chamber and collecting adjacent the valve septum when the valve septum is in a closed configuration. The method can include rotating the sample processing device to exert a first force on the liquid that is insufficient to move the liquid into the valve chamber; forming an opening in the valve septum; and rotating the sample processing device to exert a second force on the liquid to move the liquid into the valve chamber.
摘要翻译： 一种用于在样品处理装置上进行阀门的系统和方法。 该系统可以包括阀室，处理室和位于阀室和处理室之间的阀隔膜。 该系统可进一步包括与阀室的入口流体连通的流体通路，其中，当阀隔膜处于关闭构型时，该流体通道被配置为阻止液体进入阀室并且邻近阀隔开收集。 该方法可以包括旋转样品处理装置以对液体施加不足以将液体移动到阀室中的第一力; 在阀隔膜中形成开口; 并且使样品处理装置旋转以对液体施加第二力以将液体移动到阀室中。
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公开(公告)号：US08969029B2
公开(公告)日：2015-03-03
申请号：US13063945
申请日：2009-10-12
申请人： Sailaja Chandrapati , Jeffrey C. Pederson , Heather M. Webb , Jeffrey D. Smith , Kurt J. Halverson , Bryan S. Behun , Peter D. Ludowise
发明人： Sailaja Chandrapati , Jeffrey C. Pederson , Heather M. Webb , Jeffrey D. Smith , Kurt J. Halverson , Bryan S. Behun , Peter D. Ludowise
摘要： A biological sterilization indicator, system, and methods of determining the effectiveness of a sterilization process. The biological sterilization indicator can include a locus of spores, a reservoir containing a liquid, and a sterilant path positioned to provide fluid communication between ambience and the locus of spores. The reservoir can have a closed state in which the reservoir is not in fluid communication with the locus of spores and an open state in which the reservoir is in fluid communication with the locus of spores. The biological sterilization indicator system can include the biological sterilization indicator and a detection device adapted to be coupled to the biological sterilization indicator. In some embodiments, the method can include assaying the spores for a detectable change in a characteristic, and detecting substantially all of the detectable change.
摘要翻译： 一种生物灭菌指标，系统和确定灭菌过程有效性的方法。 生物灭菌指示剂可以包括孢子的位点，含有液体的储存器和定位成在气氛和孢子的位置之间提供流体连通的消毒剂通道。 储存器可以具有闭合状态，其中储存器不与孢子的轨迹流体连通，并且储存器与孢子的轨迹流体连通的打开状态。 生物灭菌指示器系统可以包括生物灭菌指示器和适于联接到生物灭菌指示器的检测装置。 在一些实施方案中，该方法可以包括测定孢子以获得特征的可检测变化，并且检测基本上所有可检测的变化。
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4.发明授权公开(公告)号：US08931331B2
公开(公告)日：2015-01-13
申请号：US13474873
申请日：2012-05-18
CPC分类号： B01L3/5027 , B01L3/5025 , B01L3/50273 , B01L3/502738 , B01L2200/0605 , B01L2300/0806 , B01L2400/0406 , B01L2400/0409 , B01L2400/0688
摘要： A system and method for volumetric metering on a sample processing device. The system can include a metering reservoir, and a waste reservoir positioned in fluid communication with a first end of the metering reservoir to catch excess liquid from the metering reservoir that exceeds a selected volume. The system can further include a capillary valve in fluid communication with the second end of the metering reservoir to inhibit liquid from exiting the metering reservoir until desired. The method can include metering the liquid by rotating the sample processing device to exert a first force on the liquid that is insufficient to move the liquid into the capillary valve, and rotating the sample processing device to exert a second force on the liquid that is greater than the first force to move the metered volume of the liquid to the process chamber via the capillary valve.
摘要翻译： 用于样品处理装置上的体积计量的系统和方法。 该系统可以包括计量储存器和废物储存器，废物储存器定位成与计量储存器的第一端流体连通以捕获超过选定体积的计量储存器中的多余液体。 该系统还可以包括与计量储存器的第二端流体连通的毛细管阀，以阻止液体离开计量储存器直至期望。 该方法可以包括通过旋转样品处理装置来对液体进行计量，以对液体施加不足以将液体移动到毛细管中的第一力，并且旋转样品处理装置以对液体施加更大的第二力 比通过毛细管阀将计量体积的液体移动到处理室的第一力。
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公开(公告)号：US20120291565A1
公开(公告)日：2012-11-22
申请号：US13474779
申请日：2012-05-18
IPC分类号： G01N1/10
CPC分类号： B01L3/502738 , B01L2200/0684 , B01L2200/0689 , B01L2200/16 , B01L2300/0803 , B01L2300/087 , B01L2300/0887 , B01L2400/0406 , B01L2400/0409 , B01L2400/0677 , B01L2400/0688
摘要： A system and method for valving on a sample processing device. The system can include a valve chamber, a process chamber, and a valve septum located between the valve chamber and the process chamber. The system can further include a fluid pathway in fluid communication with an inlet of the valve chamber, wherein the fluid pathway is configured to inhibit a liquid from entering the valve chamber and collecting adjacent the valve septum when the valve septum is in a closed configuration. The method can include rotating the sample processing device to exert a first force on the liquid that is insufficient to move the liquid into the valve chamber; forming an opening in the valve septum; and rotating the sample processing device to exert a second force on the liquid to move the liquid into the valve chamber.
摘要翻译： 一种用于在样品处理装置上进行阀门的系统和方法。 该系统可以包括阀室，处理室和位于阀室和处理室之间的阀隔膜。 该系统可进一步包括与阀室的入口流体连通的流体通路，其中，当阀隔膜处于关闭构型时，该流体通道被配置为阻止液体进入阀室并且邻近阀隔开收集。 该方法可以包括旋转样品处理装置以对液体施加不足以将液体移动到阀室中的第一力; 在阀隔膜中形成开口; 并且使样品处理装置旋转以对液体施加第二力以将液体移动到阀室中。
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公开(公告)号：USD672467S1
公开(公告)日：2012-12-11
申请号：US29392223
申请日：2011-05-18
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公开(公告)号：USD677395S1
公开(公告)日：2013-03-05
申请号：US29431512
申请日：2012-09-07
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公开(公告)号：US08840837B2
公开(公告)日：2014-09-23
申请号：US13881154
申请日：2011-10-28
CPC分类号： C12Q1/22
摘要： A biological sterilization indicator (BI) and method of using same. The BI can include a housing, and a container positioned in the housing. The container can contain a liquid and at least a portion of the container can be frangible. The BI can further include a first chamber and a second chamber. The second chamber can include at least one source of biological activity. The BI can further include a first fluid path positioned to fluidly couple the first chamber and the second chamber, and a second fluid path positioned to allow displaced gas to move out of the second chamber. The method can include moving displaced gas out of the second chamber via the second fluid path as a sterilant is moved into the second chamber via the first fluid path and/or as the liquid is moved into the second chamber via the first fluid path.
摘要翻译： 生物灭菌指示剂（BI）及其使用方法。 BI可以包括壳体和位于壳体中的容器。 容器可以容纳液体，容器的至少一部分可以是易碎的。 BI还可以包括第一室和第二室。 第二室可以包括至少一种生物活性来源。 BI还可以包括定位成流体耦合第一室和第二室的第一流体路径，以及定位成允许排出的气体移出第二室的第二流体路径。 该方法可以包括当消毒剂经由第一流体路径移动到第二室中时和/或当液体经由第一流体路径移动到第二室中时，通过第二流体路径将移动的气体移出第二室。
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公开(公告)号：US20130302849A1
公开(公告)日：2013-11-14
申请号：US13881154
申请日：2011-10-28
IPC分类号： C12Q1/22
CPC分类号： C12Q1/22
摘要： A biological sterilization indicator (BI) and method of using same. The BI can include a housing, and a container positioned in the housing. The container can contain a liquid and at least a portion of the container can be frangible. The BI can further include a first chamber and a second chamber. The second chamber can include at least one source of biological activity. The BI can further include a first fluid path positioned to fluidly couple the first chamber and the second chamber, and a second fluid path positioned to allow displaced gas to move out of the second chamber. The method can include moving displaced gas out of the second chamber via the second fluid path as a sterilant is moved into the second chamber via the first fluid path and/or as the liquid is moved into the second chamber via the first fluid path.
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公开(公告)号：US08348966B2
公开(公告)日：2013-01-08
申请号：US12852348
申请日：2010-08-06
申请人： Bruce M. McCormack , Edward Fletcher Eyster , Jeffrey D. Smith , Edward Liou , Jonathan Carver , Peter How , Joshua Druker , Martin Leugers , Shigeru Tanaka
发明人： Bruce M. McCormack , Edward Fletcher Eyster , Jeffrey D. Smith , Edward Liou , Jonathan Carver , Peter How , Joshua Druker , Martin Leugers , Shigeru Tanaka
IPC分类号： A61B17/32
CPC分类号： A61B17/320036 , A61B5/04005 , A61B5/4893 , A61B17/00234 , A61B17/149 , A61B18/148 , A61B2017/0042 , A61B2017/32006 , A61G13/124
摘要： Disclosed herein is a system for releasing a ligament. In one embodiment, the system includes a proximal handle, a tubular body, and a flexible body. The tubular body includes a proximal end and a distal end. The handle is coupled to the proximal end. The flexible body extends through the tubular body and includes a tissue cutting portion. The flexible body is longitudinally displaceable relative to the tubular body to move the tissue cutting portion between a non-deployed state and a deployed state.
摘要翻译： 本文公开了用于释放韧带的系统。 在一个实施例中，系统包括近端手柄，管状主体和柔性主体。 管状体包括近端和远端。 把手与近端相连。 柔性体延伸穿过管状主体并且包括组织切割部分。 柔性体可以相对于管状体纵向移位，以在非展开状态和展开状态之间移动组织切割部分。
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