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公开(公告)号:US07618959B2
公开(公告)日:2009-11-17
申请号:US10533501
申请日:2003-11-04
IPC分类号: C07D513/04 , A61K31/542
CPC分类号: C07D471/04 , C07D413/12 , C07D513/04
摘要: Quinoline and naphthyridine derivatives useful in the treatment of bacterial infections in mammals, particularly humans.
摘要翻译: 喹啉和萘啶衍生物可用于治疗哺乳动物,特别是人的细菌感染。
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公开(公告)号:US07648984B2
公开(公告)日:2010-01-19
申请号:US11570600
申请日:2005-07-13
IPC分类号: A61K31/542
CPC分类号: C07D471/04
摘要: Naphthalene, quinoline, quinoxaline and naphthyridine derivatives useful in the treatment of bacterial infections in mammals, particularly humans, are disclosed herein.
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公开(公告)号:US07232832B2
公开(公告)日:2007-06-19
申请号:US10533502
申请日:2003-11-04
IPC分类号: C07D401/06 , A61K31/47
CPC分类号: C07D471/04
摘要: Quinoline and naphthyridine derivatives useful in the treatment of bacterial infections in mammals, particularly humans.
摘要翻译: 喹啉和萘啶衍生物可用于治疗哺乳动物,特别是人的细菌感染。
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公开(公告)号:US07498326B2
公开(公告)日:2009-03-03
申请号:US10518655
申请日:2003-06-25
申请人: Jeffrey Michael Axten , Robert A Daines , David Thomas Davies , Timothy Francis Gallagher , Graham Elgin Jones , William Henry Miller , Neil David Pearson , Israil Pendrak
发明人: Jeffrey Michael Axten , Robert A Daines , David Thomas Davies , Timothy Francis Gallagher , Graham Elgin Jones , William Henry Miller , Neil David Pearson , Israil Pendrak
IPC分类号: C07D471/04 , A61K31/4375
CPC分类号: C07D491/04 , A61K31/03 , A61K31/535 , A61K31/54 , C07D513/04
摘要: Piperidine derivatives and pharmaceutically acceptable derivatives thereof useful in methods of treatment of bacterial infections in mammals, particularly in man. The piperidine derivatives include compounds of formula (I): wherein RA, AB, n, R3, R2 and R4 are defined herein. For example, RA is an optionally substituted bicyclic carbocyclic or heterocyclic ring system, and R4 is a group U-R5 in which R5 is an optionally substituted bicyclic heterocyclic ring system as defined herein (e.g. optionally substituted pyrido [3,2, -b][1,4] thiazin-yl).
摘要翻译: 哌啶衍生物及其药学上可接受的衍生物可用于哺乳动物,特别是人的细菌感染治疗方法。 哌啶衍生物包括式(I)的化合物:其中RA,AB,n,R 3,R 2和R 4在本文中定义。 例如,RA是任选取代的双环碳环或杂环系统,并且R 4是基团U-R 5,其中R 5是如本文所定义的任选取代的双环杂环体系(例如任选取代的吡啶并[3,2-b] [1,4]噻嗪基)。
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公开(公告)号:US20100081650A1
公开(公告)日:2010-04-01
申请号:US12620129
申请日:2009-11-17
申请人: Jeffrey Michael Axten , Robert A. Daines , David Thomas Davies , Timothy Francis Gallagher , Graham Elgin Jones , William Henry Miller , Neil David Pearson , Israil Pendrak
发明人: Jeffrey Michael Axten , Robert A. Daines , David Thomas Davies , Timothy Francis Gallagher , Graham Elgin Jones , William Henry Miller , Neil David Pearson , Israil Pendrak
IPC分类号: A61K31/542 , C07D513/02 , C07D498/02 , A61K31/5383 , C07D491/02 , A61K31/436 , A61P31/04
CPC分类号: C07D493/04 , C07D417/12 , C07D513/04
摘要: Cyclohexane and cyclohexene derivatives and pharmaceutically acceptable derivatives thereof useful in methods of treatment of bacterial infections in mammals, particularly man.
摘要翻译: 环己烷和环己烯衍生物及其药学上可接受的衍生物可用于治疗哺乳动物,特别是人的细菌感染的方法。
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公开(公告)号:US07622481B2
公开(公告)日:2009-11-24
申请号:US10518653
申请日:2003-06-25
申请人: Jeffrey Michael Axten , Robert A Daines , David Thomas Davies , Timothy Francis Gallagher , Graham Elgin Jones , William Henry Miller , Neil David Pearson , Israil Pendrak
发明人: Jeffrey Michael Axten , Robert A Daines , David Thomas Davies , Timothy Francis Gallagher , Graham Elgin Jones , William Henry Miller , Neil David Pearson , Israil Pendrak
IPC分类号: C07D513/04 , C07D471/04 , A61K31/542 , A61K31/4375
CPC分类号: C07D493/04 , C07D417/12 , C07D513/04
摘要: Cyclohexane and cyclohexene derivatives and pharmaceutically acceptable derivatives thereof useful in methods of treatment of bacterial infections in mammals, particularly man.
摘要翻译: 环己烷和环己烯衍生物及其药学上可接受的衍生物可用于治疗哺乳动物,特别是人的细菌感染的方法。
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公开(公告)号:US07605169B2
公开(公告)日:2009-10-20
申请号:US11814610
申请日:2006-01-24
IPC分类号: C07D498/04 , C07D513/04 , C07D491/052 , A61K31/542 , A61K31/436 , A61K31/5383
CPC分类号: C07D521/00 , C07D471/04
摘要: Napthyridine derivatives useful in the treatment of bacterial infections in mammals, particularly humans, are disclosed.
摘要翻译: 公开了可用于治疗哺乳动物,特别是人类细菌感染的萘啶衍生物。
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公开(公告)号:US20080139539A1
公开(公告)日:2008-06-12
申请号:US11814611
申请日:2006-01-24
IPC分类号: A61K31/542 , C07D279/16 , C07D265/28 , A61K31/5383 , C07D295/00 , A61K31/496 , A61P31/04
CPC分类号: C07D519/00 , C07D471/04 , C07D498/04 , C07D513/04
摘要: Naphthyridine and quinoline derivatives useful in the treatment of bacterial infections in mammals, particularly humans, are disclosed herein.
摘要翻译: 本文公开了可用于治疗哺乳动物,特别是人类细菌感染的萘啶和喹啉衍生物。
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公开(公告)号:US07691850B2
公开(公告)日:2010-04-06
申请号:US11628705
申请日:2005-06-15
IPC分类号: A61K31/542
CPC分类号: C07D513/04 , C07D471/04 , C07D493/04 , C07D497/04 , C07D498/04
摘要: Compounds of formula (I) and derivatives thereof: compositions containing them, their preparation and their use as antibacterials.
摘要翻译: 式(I)化合物及其衍生物:含有它们的组合物,它们的制备及其作为抗菌剂的用途。
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公开(公告)号:US20080139540A1
公开(公告)日:2008-06-12
申请号:US11814614
申请日:2006-01-24
IPC分类号: A61K31/542 , C07D279/16 , C07D265/28 , A61P31/04 , A61K31/5365
CPC分类号: C07D471/04
摘要: Naphthyridine and related derivatives useful in the treatment of bacterial infections, particularly humans, are disclosed herein.
摘要翻译: 本文公开了用于治疗细菌感染,特别是人的萘吡啶和相关衍生物。
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