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    Perfusion hyperthermia treatment system and method
    1.
    发明授权
    Perfusion hyperthermia treatment system and method 失效

    公开(公告)号：US5730720A

    公开(公告)日：1998-03-24

    申请号：US516580

    申请日：1995-08-18

    申请人： Jeffrey P. Sites ,  Philip R. Glassel ,  Michael D. Miller ,  Clark B. Norgaard ,  Thomas A. Roman ,  Dale J. Ziebarth

    发明人： Jeffrey P. Sites ,  Philip R. Glassel ,  Michael D. Miller ,  Clark B. Norgaard ,  Thomas A. Roman ,  Dale J. Ziebarth

    IPC分类号： A61M1/36 ,  A61M5/142 ,  A61M37/00

    CPC分类号： A61M1/369 ,  A61M2205/12 ,  A61M2205/3606 ,  A61M2205/366 ,  A61M2205/505 ,  A61M2230/50 ,  A61M5/14232 ,  Y10S706/924

    摘要： Method and apparatus to automatically monitor and control a perfusion hyperthermia treatment using a system including one or more programmed computers, and mechanical and sensor subsystems. The system includes a fluid path between a patient and an external fluid-treatment subsystem, wherein control of the external fluid-treatment subsystem includes feedback from sensors coupled to the patient. The resulting integrated system provides automated monitoring and control of the patient, the external fluid-treatment subsystem, and the treatment. In one embodiment, the fluid passing between the patient and the external fluid-treatment subsystem is blood. In one embodiment, an apparatus and method are provided for using a computerized system for a perfusion hyper/hypothermia treatment of a patient which obtains a body fluid having a temperature. A plurality of temperature signals representative of temperatures at each of a plurality of patient locations on or within the patient are coupled to the computer system. Measured temperatures are compared to a set of stored parameters in the computer system to generate a comparison value which controls a change in the temperature of the body fluid. The body fluid is then perfused into the patient to either warm, cool, or maintain the current temperature of the patient. In one such embodiment, the body fluid is blood withdrawn from the patient. In another such embodiment, the body fluid is saline.

    Perfusion hyperthermia treatment system and method
    2.
    发明授权
    Perfusion hyperthermia treatment system and method 失效
    灌注热疗治疗系统及方法

    公开(公告)号：US06413233B1

    公开(公告)日：2002-07-02

    申请号：US09480088

    申请日：2000-01-10

    申请人： Jeffrey P. Sites ,  Philip R. Glassel ,  Michael D. Miller ,  Clark B. Norgaard ,  Thomas A. Roman ,  Dale J. Ziebarth

    发明人： Jeffrey P. Sites ,  Philip R. Glassel ,  Michael D. Miller ,  Clark B. Norgaard ,  Thomas A. Roman ,  Dale J. Ziebarth

    IPC分类号： A61M3700

    CPC分类号： A61M1/369 ,  A61M5/14232 ,  A61M2205/12 ,  A61M2205/3606 ,  A61M2205/366 ,  A61M2205/505 ,  A61M2230/50 ,  Y10S706/924

    摘要： Method and apparatus to automatically monitor and control a perfusion hyperthermia treatment using a system including one or more programmed computers, and mechanical and sensor subsystems. The system includes a fluid path between a patient and an external fluid-treatment subsystem, wherein control of the external fluid-treatment subsystem includes feedback from sensors coupled to the patient. The resulting integrated system provides automated monitoring and control of the patient, the external fluid-treatment subsystem, and the treatment. In one embodiment, the fluid passing between the patient and the external fluid-treatment subsystem is blood. In one embodiment, an apparatus and method are provided for using a computerized system for a perfusion hyper/hypothermia treatment of a patient which obtains a body fluid having a temperature. A plurality of temperature signals representative of temperatures at each of a plurality of patient locations on or within the patient are coupled to the computer system. Measured temperatures are compared to a set of stored parameters in the computer system to generate a comparison value which controls a change in the temperature of the body fluid. The body fluid is then perfused into the patient to either warm, cool, or maintain the current temperature of the patient. In one such embodiment, the body fluid is blood withdrawn from the patient. In another such embodiment, the body fluid is saline.

    摘要翻译： 使用包括一个或多个编程计算机的系统以及机械和传感器子系统来自动监测和控制灌注热疗的方法和装置。 该系统包括患者和外部流体处理子系统之间的流体路径，其中外部流体处理子系统的控制包括耦合到患者的传感器的反馈。 所得到的集成系统提供对患者，外部流体处理子系统和治疗的自动监测和控制。 在一个实施例中，通过患者和外部流体处理子系统之间的流体是血液。 在一个实施例中，提供了一种装置和方法，用于使用计算机化系统进行用于获得具有温度的体液的患者的灌注超/低温治疗。 表示患者身上或患者内的多个患者位置中的每一个处的温度的多个温度信号被耦合到计算机系统。 将测量的温度与计算机系统中的一组存储的参数进行比较，以产生控制体液温度变化的比较值。 然后将体液灌注到患者中以加热，冷却或维持患者的当前温度。 在一个这样的实施例中，体液是从患者抽出的血液。 在另一个这样的实施方案中，体液是盐水。

    Pressure sensor configurations for implantable medical electrical leads
    4.
    发明授权
    Pressure sensor configurations for implantable medical electrical leads 有权
    用于植入式医疗电线的压力传感器配置

    公开(公告)号：US07886608B2

    公开(公告)日：2011-02-15

    申请号：US12544342

    申请日：2009-08-20

    申请人： Kamal Deep Mothilal ,  Michael A. Schugt ,  David A. Ruben ,  Jonathan P. Roberts ,  Clark B. Norgaard ,  Lary R. Larson

    发明人： Kamal Deep Mothilal ,  Michael A. Schugt ,  David A. Ruben ,  Jonathan P. Roberts ,  Clark B. Norgaard ,  Lary R. Larson

    IPC分类号： G01L9/12

    CPC分类号： A61N1/056 ,  A61B5/0215 ,  A61B2562/0247 ,  A61B2562/028 ,  A61B2562/182 ,  A61N1/0573

    摘要： An implantable pressure sensor, which may be incorporated within an implantable medical electrical lead, includes an insulative sidewall, which contains a gap capacitor and an integrated circuit. The insulative sidewall of the pressure sensor includes a pressure sensitive diaphragm portion, and the gap capacitor includes a first electrode plate, which is attached to an interior surface of the diaphragm portion of the sidewall, and a second electrode plate, which is spaced apart from the first electrode plate and coupled to the integrated circuit, which is coupled, through the sidewall, to a supply contact and a ground contact. A conductive layer extends over one of the interior surface of the diaphragm portion of the sidewall and an exterior surface of the diaphragm portion; and the conductive layer is coupled to the ground contact to either shield or ground the first electrode plate.

    摘要翻译： 可植入的压力传感器，其可并入可植入医疗电引线内，包括绝缘侧壁，其包含间隙电容器和集成电路。 压力传感器的绝缘侧壁包括压敏膜部分，并且间隙电容器包括附接到侧壁的隔膜部分的内表面的第一电极板和与侧壁隔膜部分隔开的第二电极板 第一电极板并且耦合到集成电路，其通过侧壁耦合到电源触点和接地触点。 导电层在侧壁的隔膜部分的内表面和隔膜部分的外表面之一上延伸; 并且所述导电层耦合到所述接地触头以屏蔽或接地所述第一电极板。

    Conformal antenna for implantable medical device and implantable medical device with such antenna
    5.
    发明授权
    Conformal antenna for implantable medical device and implantable medical device with such antenna 有权
    用于可植入医疗设备的保形天线和具有这种天线的可植入医疗设备

    公开(公告)号：US08903497B2

    公开(公告)日：2014-12-02

    申请号：US12895083

    申请日：2010-09-30

    申请人： Clark B. Norgaard ,  Michael W. Barror ,  Douglas D. Nippoldt ,  Tony A. Ulrich

    发明人： Clark B. Norgaard ,  Michael W. Barror ,  Douglas D. Nippoldt ,  Tony A. Ulrich

    IPC分类号： A61N1/372 ,  A61B5/00 ,  H01F5/02

    CPC分类号： A61N1/37229 ,  A61B5/0031 ,  A61N1/37205 ,  H01F5/02 ,  Y10T29/49016

    摘要： System and method for making an antenna. An implantable medical device has a housing, a bobbin and a coil. The housing has an interior generally tubular cross-section with a longitudinal axis, the housing having a lateral portion of a segment of the tubular cross-section along the longitudinal axis. The bobbin has a first side nearest to the interior of the housing and a second side opposite the first side. The coil, wound around the bobbin on a winding axis orthogonal to the longitudinal axis of the tubular cross-section, has a greater number of complete turns proximate the second side of the bobbin than proximate the first side of the bobbin, with the coil having a cross-sectional shape selected for a space between the bobbin and the interior of the housing in the lateral portion of the segment of the tubular cross-section along the longitudinal axis of the housing.

    摘要翻译： 制造天线的系统和方法。 可植入医疗装置具有壳体，线轴和线圈。 壳体具有内部具有纵向轴线的大致管状的横截面，壳体具有沿着纵向轴线的管状横截面的一部分的横向部分。 线轴具有最靠近壳体内部的第一侧和与第一侧相对的第二侧。 线圈缠绕在与管状横截面的纵向轴线正交的绕线轴上的线轴上，靠近线轴第二侧的完整匝数比靠近线轴的第一侧更多，线圈具有 所述截面形状被选择为所述筒管和所述壳体内部之间的空间，所述横截面形状沿着所述壳体的纵向轴线在所述管状横截面的所述段的横向部分的横向部分中。

    PRESSURE SENSOR CONFIGURATIONS FOR IMPLANTABLE MEDICAL ELECTRICAL LEADS
    8.
    发明申请
    PRESSURE SENSOR CONFIGURATIONS FOR IMPLANTABLE MEDICAL ELECTRICAL LEADS 有权
    用于可植入式医疗电源的压力传感器配置

    公开(公告)号：US20090308169A1

    公开(公告)日：2009-12-17

    申请号：US12544342

    申请日：2009-08-20

    申请人： Kamal Deep Mothilal ,  Michael A. Schugt ,  David A. Ruben ,  Jonathan P. Roberts ,  Clark B. Norgaard ,  Lary R. Larson

    发明人： Kamal Deep Mothilal ,  Michael A. Schugt ,  David A. Ruben ,  Jonathan P. Roberts ,  Clark B. Norgaard ,  Lary R. Larson

    IPC分类号： G01L9/12

    CPC分类号： A61N1/056 ,  A61B5/0215 ,  A61B2562/0247 ,  A61B2562/028 ,  A61B2562/182 ,  A61N1/0573

    摘要： An implantable pressure sensor, which may be incorporated within an implantable medical electrical lead, includes an insulative sidewall, which contains a gap capacitor and an integrated circuit. The insulative sidewall of the pressure sensor includes a pressure sensitive diaphragm portion, and the gap capacitor includes a first electrode plate, which is attached to an interior surface of the diaphragm portion of the sidewall, and a second electrode plate, which is spaced apart from the first electrode plate and coupled to the integrated circuit, which is coupled, through the sidewall, to a supply contact and a ground contact. A conductive layer extends over one of the interior surface of the diaphragm portion of the sidewall and an exterior surface of the diaphragm portion; and the conductive layer is coupled to the ground contact to either shield or ground the first electrode plate.

    摘要翻译： 可植入的压力传感器，其可并入可植入医疗电引线内，包括绝缘侧壁，其包含间隙电容器和集成电路。 压力传感器的绝缘侧壁包括压敏膜部分，并且间隙电容器包括附接到侧壁的隔膜部分的内表面的第一电极板和与侧壁隔膜部分隔开的第二电极板 第一电极板并且耦合到集成电路，其通过侧壁耦合到电源触点和接地触点。 导电层在侧壁的隔膜部分的内表面和隔膜部分的外表面之一上延伸; 并且所述导电层耦合到所述接地触头以屏蔽或接地所述第一电极板。

    CONFORMAL ANTENNA FOR IMPLANTABLE MEDICAL DEVICE AND IMPLANTABLE MEDICAL DEVICE WITH SUCH ANTENNA
    10.
    发明申请
    CONFORMAL ANTENNA FOR IMPLANTABLE MEDICAL DEVICE AND IMPLANTABLE MEDICAL DEVICE WITH SUCH ANTENNA 有权
    具有这种天线的可植入医疗器械和可植入医疗装置的合适天线

    公开(公告)号：US20120081201A1

    公开(公告)日：2012-04-05

    申请号：US12895083

    申请日：2010-09-30

    申请人： Clark B. Norgaard ,  Michael W. Barror ,  Douglas D. Nippoldt ,  Tony A. Ulrich

    发明人： Clark B. Norgaard ,  Michael W. Barror ,  Douglas D. Nippoldt ,  Tony A. Ulrich

    IPC分类号： H01F38/14 ,  H01P11/00

    CPC分类号： A61N1/37229 ,  A61B5/0031 ,  A61N1/37205 ,  H01F5/02 ,  Y10T29/49016

    摘要： System and method for making an antenna. An implantable medical device has a housing, a bobbin and a coil. The housing has an interior generally tubular cross-section with a longitudinal axis, the housing having a lateral portion of a segment of the tubular cross-section along the longitudinal axis. The bobbin has a first side nearest to the interior of the housing and a second side opposite the first side. The coil, wound around the bobbin on a winding axis orthogonal to the longitudinal axis of the tubular cross-section, has a greater number of complete turns proximate the second side of the bobbin than proximate the first side of the bobbin, with the coil having a cross-sectional shape selected for a space between the bobbin and the interior of the housing in the lateral portion of the segment of the tubular cross-section along the longitudinal axis of the housing.

    摘要翻译： 制造天线的系统和方法。 可植入医疗装置具有壳体，线轴和线圈。 壳体具有内部具有纵向轴线的大致管状的横截面，壳体具有沿着纵向轴线的管状横截面的一部分的横向部分。 线轴具有最靠近壳体内部的第一侧和与第一侧相对的第二侧。 线圈缠绕在与管状横截面的纵向轴线正交的绕线轴上的线轴上，靠近线轴第二侧的完整匝数比靠近线轴的第一侧更多，线圈具有 所述截面形状被选择为所述筒管和所述壳体内部之间的空间，所述横截面形状沿着所述壳体的纵向轴线在所述管状横截面的所述段的横向部分的横向部分中。