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公开(公告)号:US08343980B2
公开(公告)日:2013-01-01
申请号:US12688163
申请日:2010-01-15
申请人: Jesus Gonzalez, III , Dean Wilson , Andreas Termin , Peter D. J. Grootenhuis , Yulian Zhang , Benjamin Petzoldt , Lev T. D. Fanning , Timothy Neubert , Roger Tung , Esther Martinborough , Nicole Hilgraf
发明人: Jesus Gonzalez, III , Dean Wilson , Andreas Termin , Peter D. J. Grootenhuis , Yulian Zhang , Benjamin Petzoldt , Lev T. D. Fanning , Timothy Neubert , Roger Tung , Esther Martinborough , Nicole Hilgraf
IPC分类号: A61K31/517 , A61K31/496 , A61K31/4523 , A61P19/02 , A61P25/06 , A61P25/08 , A61P29/02 , A61P35/00 , C07D401/04 , C07D403/04
CPC分类号: C07D239/94 , C07D239/91 , C07D401/04 , C07D401/12 , C07D401/14 , C07D403/12 , C07D403/14 , C07D405/12 , C07D405/14 , C07D409/04 , C07D409/12 , C07D413/12 , C07D417/12 , C07D471/04 , C07D487/04
摘要: The present invention relates to compounds useful as inhibitors of voltage-gated sodium channels and calcium channels. The invention also provides pharmaceutically acceptable compositions comprising the compounds of the invention and methods of using the compositions in the treatment of various disorders.
摘要翻译: 本发明涉及可用作电压门控钠通道和钙通道抑制剂的化合物。 本发明还提供包含本发明化合物的药学上可接受的组合物和使用该组合物治疗各种疾病的方法。
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公开(公告)号:US20110021495A1
公开(公告)日:2011-01-27
申请号:US12688163
申请日:2010-01-15
申请人: Jesus Gonzalez, III , Dean Wilson , Andreas Termin , Peter D. J. Grootenhuis , Yulian Zhang , Benjamin Petzoldt , Lev T.D. Fanning , Timothy Neubert , Roger Tung , Esther Martinborough , Nicole Hilgraf
发明人: Jesus Gonzalez, III , Dean Wilson , Andreas Termin , Peter D. J. Grootenhuis , Yulian Zhang , Benjamin Petzoldt , Lev T.D. Fanning , Timothy Neubert , Roger Tung , Esther Martinborough , Nicole Hilgraf
IPC分类号: A61K31/397 , C07D403/04 , A61K31/517 , C07D401/14 , C07D413/14 , A61K31/5377 , A61P29/00 , A61P25/00 , A61P19/00 , C12N5/07
CPC分类号: C07D239/94 , C07D239/91 , C07D401/04 , C07D401/12 , C07D401/14 , C07D403/12 , C07D403/14 , C07D405/12 , C07D405/14 , C07D409/04 , C07D409/12 , C07D413/12 , C07D417/12 , C07D471/04 , C07D487/04
摘要: The present invention relates to compounds useful as inhibitors of voltage-gated sodium channels and calcium channels. The invention also provides pharmaceutically acceptable compositions comprising the compounds of the invention and methods of using the compositions in the treatment of various disorders.
摘要翻译: 本发明涉及可用作电压门控钠通道和钙通道抑制剂的化合物。 本发明还提供包含本发明化合物的药学上可接受的组合物和使用该组合物治疗各种疾病的方法。
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公开(公告)号:US08153642B2
公开(公告)日:2012-04-10
申请号:US12714871
申请日:2010-03-01
申请人: Jesus Gonzalez, III , Dean Wilson , Andreas Termin , Peter Grootenhuis , Yulian Zhang , Benjamin Petzoldt , Lev Fanning , Timothy Neubert , Roger Tung , Esther Martinborough , Nicole Hilgraf
发明人: Jesus Gonzalez, III , Dean Wilson , Andreas Termin , Peter Grootenhuis , Yulian Zhang , Benjamin Petzoldt , Lev Fanning , Timothy Neubert , Roger Tung , Esther Martinborough , Nicole Hilgraf
IPC分类号: A61K31/517 , A61P19/02 , A61P25/06 , A61P25/08 , A61P29/02 , A61P35/00 , C07D239/94 , C07D403/12
CPC分类号: C07D239/91 , C07D239/94 , C07D401/04 , C07D401/12 , C07D401/14 , C07D403/12 , C07D403/14 , C07D405/12 , C07D405/14 , C07D409/04 , C07D409/12 , C07D413/12 , C07D417/12 , C07D471/04 , C07D487/04
摘要: The present invention relates to compounds useful as inhibitors of voltage-gated sodium channels and calcium channels. The invention also provides pharmaceutically acceptable compositions comprising the compounds of the invention and methods of using the compositions in the treatment of various disorders.
摘要翻译: 本发明涉及可用作电压门控钠通道和钙通道抑制剂的化合物。 本发明还提供包含本发明化合物的药学上可接受的组合物和使用该组合物治疗各种疾病的方法。
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公开(公告)号:US20060217377A1
公开(公告)日:2006-09-28
申请号:US10935008
申请日:2004-09-02
申请人: Jesus Gonzalez , Dean Wilson , Andreas Termin , Peter Grootenhuis , Yulian Zhang , Benjamin Petzoldt , Lev Fanning , Timothy Neubert , Roger Tung , Esther Martinborough , Nicole Zimmerman
发明人: Jesus Gonzalez , Dean Wilson , Andreas Termin , Peter Grootenhuis , Yulian Zhang , Benjamin Petzoldt , Lev Fanning , Timothy Neubert , Roger Tung , Esther Martinborough , Nicole Zimmerman
IPC分类号: A61K31/5377 , A61K31/517 , C07D413/02 , C07D43/02
CPC分类号: C07D239/91 , C07D239/94 , C07D401/04 , C07D401/12 , C07D401/14 , C07D403/12 , C07D403/14 , C07D405/12 , C07D405/14 , C07D409/04 , C07D409/12 , C07D413/12 , C07D417/12 , C07D471/04 , C07D487/04
摘要: The present invention relates to compounds useful as inhibitors of voltage-gated sodium channels and calcium channels. The invention also provides pharmaceutically acceptable compositions comprising the compounds of the invention and methods of using the compositions in the treatment of various disorders.
摘要翻译: 本发明涉及可用作电压门控钠通道和钙通道抑制剂的化合物。 本发明还提供包含本发明化合物的药学上可接受的组合物和使用该组合物治疗各种疾病的方法。
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