公开(公告)号：US20220126370A1

公开(公告)日：2022-04-28

申请号：US17511073

申请日：2021-10-26

申请人： Jian Liu ,  Shuang Bai

发明人： Jian Liu ,  Shuang Bai

IPC分类号： B22F10/36 ,  B22F12/49 ,  B22F12/58 ,  B22F10/85 ,  B22F1/065 ,  B22F1/062 ,  B22F1/068 ,  B33Y10/00 ,  B33Y30/00 ,  B33Y70/10

摘要： Methods and apparatuses for AM of all-in-one radiation shielding components from multi-material metal alloys, metal matrix, MMCs, and/or gradated compositions of the same are disclosed, comprising: providing an apparatus having: an energy source; a scanner; a powder system for powder(s); a powder delivery system; a shielding gas; and a computer coupled to and configured to control the energy source, scanner, powder system, and powder delivery system to deposit layers of the sample; programming the computer with specifications of the sample; using the computer to control electromagnetic radiation, mixing ratio, and powder deposition parameters based on the specifications of the sample; and using the autofocusing scanner to focus and scan the electromagnetic radiation onto the sample while the powders are concurrently deposited by the powder delivery system onto the sample to create a melting pool to deposit one or more layers onto the sample. Other embodiments are described and claimed.

公开(公告)号：US20210252643A1

公开(公告)日：2021-08-19

申请号：US16791892

申请日：2020-02-14

申请人： Jian Liu ,  Shuang Bai

发明人： Jian Liu ,  Shuang Bai

IPC分类号： B23K26/352 ,  H01S3/094

摘要： Methods and systems for surface structuring to increase emissivity of one or more samples comprising: generating electromagnetic radiation from a femtosecond fiber laser, wherein the electromagnetic radiation comprises a wavelength, a pulse repetition rate, a pulse width, a pulse energy, and an average power; coupling the electromagnetic radiation from the femtosecond fiber laser to an autofocusing scanner, wherein the autofocusing scanner is configured to scan and focus the electromagnetic radiation onto the one or more samples; and using a computer to adjust the pulse repetition rate and the pulse energy of the femtosecond fiber laser and to control the autofocusing scanner to scan and focus the electromagnetic radiation onto the one or more samples to fabricate micro spikes onto the surface of the one or more samples in order to increase the emissivity of the one or more samples. Other embodiments are described and claimed.

公开(公告)号：US20130004498A1

公开(公告)日：2013-01-03

申请号：US13364135

申请日：2012-02-01

申请人： Shuang Bai ,  Daniel S. Chen ,  Roel Funke ,  Priti Hegde ,  Louie Naumovski

发明人： Shuang Bai ,  Daniel S. Chen ,  Roel Funke ,  Priti Hegde ,  Louie Naumovski

IPC分类号： A61K39/395 ,  A61P35/00 ,  A61P35/02 ,  A61P9/00

CPC分类号： C07K16/2896 ,  A61K39/395 ,  A61K2039/507 ,  A61K2039/545 ,  C07K16/22 ,  C07K2317/56 ,  A61K2300/00

摘要： The present invention concerns dosing of anti-EGFL7 antibodies for cancer therapy.

摘要翻译： 本发明涉及抗EGFL7抗体用于癌症治疗的剂量。

公开(公告)号：US08456630B2

公开(公告)日：2013-06-04

申请号：US13103030

申请日：2011-05-06

申请人： Shuang Bai

发明人： Shuang Bai

IPC分类号： G01J3/44

CPC分类号： G01J3/44 ,  G01J3/0218 ,  G01J3/0259 ,  G01N21/658

摘要： Methods and systems for enhanced SERS sensing are disclosed, including generating electromagnetic radiation from a fiber laser; coupling the radiation to a SERS sensor comprising: a fiber comprising a first end and a second end, wherein the first end is coupled to the fiber laser and the second end is deposited with one or more metal nanoparticles; an in-line fiber grating integrated into the fiber between the first and the second end; a spectrometer configured to measure a spectrum produced by the in-line fiber grating; and a micro-processor configured to control the fiber laser and the spectrometer; exciting one or more molecules adsorbed on the surface of the one or more metal nanoparticles to generate a Raman signal; coupling the signal into the fiber; separating the signal into its wavelength components with the in-line fiber grating; and measuring the wavelength components with the spectrometer. Other embodiments are described and claimed.

摘要翻译： 公开了用于增强SERS感测的方法和系统，包括从光纤激光器产生电磁辐射; 将辐射耦合到SERS传感器，其包括：包括第一端和第二端的光纤，其中所述第一端耦合到所述光纤激光器，并且所述第二端被沉积有一个或多个金属纳米颗粒; 在第一和第二端之间集成到光纤中的在线光纤光栅; 配置为测量由直列光纤光栅产生的光谱的光谱仪; 以及配置成控制所述光纤激光器和所述光谱仪的微处理器; 激发吸附在一个或多个金属纳米粒子的表面上的一个或多个分子以产生拉曼信号; 将信号耦合到光纤中; 使用直列光纤光栅将信号分离成其波长分量; 并用光谱仪测量波长分量。 描述和要求保护其他实施例。

公开(公告)号：US20120281209A1

公开(公告)日：2012-11-08

申请号：US13103030

申请日：2011-05-06

申请人： Shuang Bai

发明人： Shuang Bai

IPC分类号： G01J3/44 ,  B82Y15/00

CPC分类号： G01J3/44 ,  G01J3/0218 ,  G01J3/0259 ,  G01N21/658

摘要： Methods and systems for enhanced SERS sensing are disclosed, including generating electromagnetic radiation from a fiber laser; coupling the radiation to a SERS sensor comprising: a fiber comprising a first end and a second end, wherein the first end is coupled to the fiber laser and the second end is deposited with one or more metal nanoparticles; an in-line fiber grating integrated into the fiber between the first and the second end; a spectrometer configured to measure a spectrum produced by the in-line fiber grating; and a micro-processor configured to control the fiber laser and the spectrometer; exciting one or more molecules adsorbed on the surface of the one or more metal nanoparticles to generate a Raman signal; coupling the signal into the fiber; separating the signal into its wavelength components with the in-line fiber grating; and measuring the wavelength components with the spectrometer. Other embodiments are described and claimed.

摘要翻译： 公开了用于增强SERS感测的方法和系统，包括从光纤激光器产生电磁辐射; 将辐射耦合到SERS传感器，其包括：包括第一端和第二端的光纤，其中所述第一端耦合到所述光纤激光器，并且所述第二端被沉积有一个或多个金属纳米颗粒; 在第一和第二端之间集成到光纤中的在线光纤光栅; 配置为测量由直列光纤光栅产生的光谱的光谱仪; 以及配置成控制所述光纤激光器和所述光谱仪的微处理器; 激发吸附在一个或多个金属纳米粒子的表面上的一个或多个分子以产生拉曼信号; 将信号耦合到光纤中; 使用直列光纤光栅将信号分离成其波长分量; 并用光谱仪测量波长分量。 描述和要求保护其他实施例。