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1.发明授权Corynebacteria strain having enhanced 5′-xanthosine monophosphate productivity and a method of producing 5′-xanthosine monophosphate using the same 有权具有增强的5'-黄嘌呤一磷酸生产力的棒状杆菌菌株和使用其制备5'-黄苷单磷酸的方法公开(公告)号：US08815545B2
公开(公告)日：2014-08-26
申请号：US13140321
申请日：2009-12-17
申请人： Jinman Cho , Hye Won Kim , Jinman Lee , Ji-Hye Lee , Yoon Seok Oh , Jang Hee Park
发明人： Jinman Cho , Hye Won Kim , Jinman Lee , Ji-Hye Lee , Yoon Seok Oh , Jang Hee Park
CPC分类号： C12N9/0006 , C12P19/32
摘要： Disclosed is a novel microorganism which has a malate dehydrogenase activity higher than that of a wild-type. Also, a recombinant vector which has the structure shown in the cleavage map of FIG. 1, a Corynebacteria strain transformed therewith, and a method of producing 5′-xanthosine monophosphate by culturing the transformed strain are disclosed.
摘要翻译： 公开了具有比野生型高的苹果酸脱氢酶活性的新型微生物。 此外，具有图1的切割图所示结构的重组载体。 1，通过转化的棒状杆菌菌株和通过培养转化菌株来生产5'-芒硝单磷酸的方法。
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2.发明申请Corynebacteria Strain Having Enhanced 5'-Xanthosine Monophosphate Productivity and a Method of Producing 5'-Xanthosine Monophosphate Using the Same 有权具有增强的5'-芒硝单磷酸生产力的棒状杆菌菌株及其使用同样方法产生5'-Xanthosine Monophosphate公开(公告)号：US20110300582A1
公开(公告)日：2011-12-08
申请号：US13140321
申请日：2009-12-17
申请人： Jinman Cho , Hye Won Kim , Jinman Lee , Ji-Hye Lee , Yoon Seok Oh , Jang Hee Park
发明人： Jinman Cho , Hye Won Kim , Jinman Lee , Ji-Hye Lee , Yoon Seok Oh , Jang Hee Park
CPC分类号： C12N9/0006 , C12P19/32
摘要： Disclosed is a novel microorganism which has a malate dehydrogenase activity higher than that of a wild-type. Also, a recombinant vector which has the structure shown in the cleavage map of FIG. 1, a Corynebacteria strain transformed therewith, and a method of producing 5′-xanthosine monophosphate by culturing the transformed strain are disclosed.
摘要翻译： 公开了具有比野生型高的苹果酸脱氢酶活性的新型微生物。 此外，具有图1的切割图所示结构的重组载体。 1，通过转化的棒状杆菌菌株和通过培养转化菌株来生产5'-芒硝单磷酸的方法。
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3.发明授权Microorganism with improved production of 5′-xanthosine monophosphate and 5′-guanine monophosphate, and production method of 5′-xanthosine monophosphate and 5′-guanine monophosphate using same 有权具有5'-黄嘌呤单磷酸和5'-鸟嘌呤一磷酸的生产的微生物，以及使用其的5'-芒硝单磷酸和5'-鸟嘌呤一磷酸的生产方法公开(公告)号：US08859236B2
公开(公告)日：2014-10-14
申请号：US13635801
申请日：2011-03-17
申请人： Jin Man Cho , Jin Nam Lee , Hye Won Kim , Ji Hye Lee , Nan Young Yoon , Kwang Woo Lee , Yoon Seok Oh , Jang Hee Park
发明人： Jin Man Cho , Jin Nam Lee , Hye Won Kim , Ji Hye Lee , Nan Young Yoon , Kwang Woo Lee , Yoon Seok Oh , Jang Hee Park
CPC分类号： C12N15/77 , C12N9/0026 , C12P19/32 , C12Y105/99008 , Y02P20/582
摘要： The present invention relates to a microorganism with improved production of 5′-xanthosine monophosphate and 5′-guanine monophosphate, and more specifically, to a Corynebacterium sp. microorganism having increased proline dehydrogenase activity compared with an intrinsic activity thereof, a method for producing 5′-xanthosine monophosphate or 5′-guanine monophosphate from the culture medium obtained by culturing the transformed microorganism, and a use of the microorganism for production of 5′-xanthosine monophosphate or 5′-guanine monophosphate.
摘要翻译： 本发明涉及一种具有5'-黄嘌呤一磷酸和5'-鸟嘌呤一磷酸的生产的微生物，更具体地说，涉及一种棒状杆菌属。 与其内在活性相比具有增加的脯氨酸脱氢酶活性的微生物，从通过培养转化的微生物获得的培养基中生产5'-黄嘌呤一磷酸或5'-鸟嘌呤一磷酸的方法，以及该微生物用于生产5' 单磷酸黄烷磷酸酯或5'-鸟嘌呤单磷酸酯。
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4.发明申请Microorganism with Improved Production of 5'-Xanthosine Monophosphate and 5'-Guanine Monophosphate, and Production Method of 5'-Xanthosine Monophosphate and 5'-Guanine Monophosphate Using Same 有权具有改善的5'-芒硝单磷酸和5'-鸟嘌呤单磷酸的生产的微生物，以及使用其的5'-芒硝单磷酸和5'-鸟嘌呤一磷酸的生产方法公开(公告)号：US20130095529A1
公开(公告)日：2013-04-18
申请号：US13635801
申请日：2011-03-17
申请人： Jin Man Cho , Jin Nam Lee , Hye Won Kim , Ji Hye Lee , Nan Young Yoon , Kwang Woo Lee , Yoon Seok Oh , Jang Hee Park
发明人： Jin Man Cho , Jin Nam Lee , Hye Won Kim , Ji Hye Lee , Nan Young Yoon , Kwang Woo Lee , Yoon Seok Oh , Jang Hee Park
IPC分类号： C12N15/77
CPC分类号： C12N15/77 , C12N9/0026 , C12P19/32 , C12Y105/99008 , Y02P20/582
摘要： The present invention relates to a microorganism with improved production of 5′-xanthosine monophosphate and 5′-guanine monophosphate, and more specifically, to a Corynebacterium sp. microorganism having increased proline dehydrogenase activity compared with an intrinsic activity thereof, a method for producing 5′-xanthosine monophosphate or 5′-guanine monophosphate from the culture medium obtained by culturing the transformed microorganism, and a use of the microorganism for production of 5′-xanthosine monophosphate or 5′-guanine monophosphate.
摘要翻译： 本发明涉及一种具有5'-黄嘌呤一磷酸和5'-鸟嘌呤一磷酸的生产的微生物，更具体地说，涉及一种棒状杆菌属。 与其内在活性相比具有增加的脯氨酸脱氢酶活性的微生物，从通过培养转化的微生物获得的培养基中生产5'-黄嘌呤一磷酸或5'-鸟嘌呤一磷酸的方法，以及该微生物用于生产5' 单磷酸黄烷磷酸酯或5'-鸟嘌呤单磷酸酯。
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5.发明授权Corynebacteria strain for enhancement of 5′-guanosine monophosphate productivity and a method of producing 5′-guanosine monophosphate using the same 有权用于增强5'-鸟苷一磷酸生产力的棒状杆菌菌株和使用其制备5'-鸟苷酸单磷酸的方法公开(公告)号：US08530200B2
公开(公告)日：2013-09-10
申请号：US13140302
申请日：2009-12-17
申请人： Jinman Cho , Hye Won Kim , Yoon Seok Oh , Jang Hee Park
发明人： Jinman Cho , Hye Won Kim , Yoon Seok Oh , Jang Hee Park
CPC分类号： C12P19/32 , C12N9/0006 , Y02P20/582
摘要： Disclosed is a method of producing 5′-guanosine monophosphate using a novel microorganism which has a malate dehydrogenase activity higher than that of a wild-type, thereby showing improved ATP productivity. Also, a novel microorganism is disclosed. The method comprises: culturing the corynebacteria strain which is enhanced in malate dehydrogenase activity over the endogenous activity, thus producing ATP in high yield; producing XMP in the culture; adding to the culture an enzyme or microorganism having XMP amination activity; and obtaining GMP from the culture.
摘要翻译： 公开了一种使用具有比野生型高的苹果酸脱氢酶活性的新型微生物生产5'-鸟苷酸单磷酸酯的方法，从而显示出提高的ATP生产率。 另外，公开了一种新型微生物。 该方法包括：培养在内源性活性中苹果酸脱氢酶活性增强的棒状杆菌菌株，从而以高产率产生ATP; 在文化中生产XMP; 向培养基中加入具有XMP胺化活性的酶或微生物; 并从文化中获得GMP。
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6.发明授权Microorganism for producing riboflavin and method for producing riboflavin using the same 有权用于生产核黄素的微生物及使用其生产核黄素的方法公开(公告)号：US07166456B2
公开(公告)日：2007-01-23
申请号：US10454221
申请日：2003-06-04
申请人： Kwang Ho Lee , Young Hoon Park , Jong Kwon Han , Jang Hee Park , Kyung Han Lee , Hyang Choi
发明人： Kwang Ho Lee , Young Hoon Park , Jong Kwon Han , Jang Hee Park , Kyung Han Lee , Hyang Choi
摘要： Riboflavin-producing Bacillus subtilis which is resistant to proline analogue, and a method for producing riboflavin using the Bacillus subtilis are provided.
摘要翻译： 提供了对脯氨酸类似物具有抗性的产生核黄素的枯草芽孢杆菌，以及使用枯草芽孢杆菌生产核黄素的方法。
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7.发明授权Microorganism for producing riboflavin and method for producing riboflavin using the same 有权用于生产核黄素的微生物及使用其生产核黄素的方法公开(公告)号：US07078222B2
公开(公告)日：2006-07-18
申请号：US10454220
申请日：2003-06-04
申请人： Kwang Ho Lee , Young Hoon Park , Jong Kwon Han , Jang Hee Park , Kyung Han Lee , Hyang Choi
发明人： Kwang Ho Lee , Young Hoon Park , Jong Kwon Han , Jang Hee Park , Kyung Han Lee , Hyang Choi
摘要： Riboflavin-producing Bacillus subtilis which is resistant to threonine analogue, and a method for producing riboflavin using the Bacillus subtilis are provided.The subject Bacillus subtilis referred to as Bacillus subtilis CJKB0002 has the accession number KCCM-10446, having been deposited in Korean Culture Center of Microorganisms (KCCM), 361-221, Yurim B/D, Hongie-1-dong, Seodaemun-gut, Seoul 120-091 Republic of Korea, on Nov. 18, 2002.
摘要翻译： 提供了对苏氨酸类似物具有抗性的产生核黄素的枯草芽孢杆菌，以及使用枯草芽孢杆菌生产核黄素的方法。 被称为枯草芽孢杆菌CJKB0002的枯草芽孢杆菌具有保藏在韩国微生物培养中心（KCCM），361-221，Yurim B / D，Hongie-1-dong，Seodaemun-gut的登录号KCCM-10446， 汉城120-091大韩民国，2002年11月18日。
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