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    Container for a medicinal liquid
    1.
    发明授权
    Container for a medicinal liquid 有权
    药用液体容器

    公开(公告)号：US07963955B2

    公开(公告)日：2011-06-21

    申请号：US10754499

    申请日：2004-01-12

    申请人： Bernhard Freund ,  Dieter Hochrainer ,  Heinrich Kladders ,  Bernd Zierenberg ,  Joachim Eicher ,  Johannes Geser ,  Martin Essing ,  Holger Reinecke

    发明人： Bernhard Freund ,  Dieter Hochrainer ,  Heinrich Kladders ,  Bernd Zierenberg ,  Joachim Eicher ,  Johannes Geser ,  Martin Essing ,  Holger Reinecke

    IPC分类号： A61B19/00

    CPC分类号： B65D83/0061 ,  E05F3/10 ,  E05F3/102 ,  E05Y2900/602

    摘要： Foil bags are used as a primary packaging for liquids, the bags permitting the liquid to be taken therefrom without the application of a considerable amount of force. A container is provided for a medicinal liquid, the container being gas-tight and liquid-tight so that it is storable over many months. The container includes a collapsible foil bag on which a flange, which is stable in respect of shape, is disposed. The flange is designed for fitting onto a discharge connection member. The container can be disposed in a casing which is stable in respect of shape. The medicinal liquid does not come into contact with air and is protected from the effect of light. The medicinal liquid may be dispensed from the foil bag in many partial quantities over a prolonged period of time, with a respective partial amount thereof being converted into an aerosol by means of an atomizer.

    摘要翻译： 箔袋用作液体的主要包装，允许从其中取出液体的袋不施加相当大的力。 为药液提供容器，该容器是气密和液密的，以便可以在几个月内储存。 容器包括可折叠的箔袋，其上设置有关于形状稳定的凸缘。 凸缘设计用于安装在排放连接构件上。 容器可以设置在相对于形状稳定的壳体中。 药用液体不会与空气接触并被保护免受光线的影响。 医药液体可以在较长的时间段内以多个部分量从箔袋中分配，其相应的部分量通过雾化器转化成气溶胶。

    Device for producing high pressure in a fluid in miniature
    2.
    发明授权
    Device for producing high pressure in a fluid in miniature 失效
    用于在微型流体中产生高压的装置

    公开(公告)号：US06918547B2

    公开(公告)日：2005-07-19

    申请号：US10807447

    申请日：2004-03-24

    申请人： Joachim Jaeger ,  Pasquale Cirillo ,  Joachim Eicher ,  Johannes Geser ,  Bernhard Freund ,  Bernd Zierenberg

    发明人： Joachim Jaeger ,  Pasquale Cirillo ,  Joachim Eicher ,  Johannes Geser ,  Bernhard Freund ,  Bernd Zierenberg

    IPC分类号： A61M11/00 ,  A47K5/12 ,  A61M15/00 ,  B05B9/043 ,  B05B11/00 ,  B05B11/06 ,  B65D83/76 ,  F04B9/14 ,  F04B53/10 ,  F04B53/12 ,  F16K20060101

    CPC分类号： A61M15/0065 ,  A61M15/00 ,  A61M15/0068 ,  A61M15/0071 ,  A61M15/0081 ,  A61M2205/7545 ,  B05B11/00412 ,  B05B11/3001 ,  B05B11/3067 ,  B05B11/308 ,  B05B11/309 ,  B05B11/3091 ,  F04B53/125 ,  Y10T137/7909 ,  Y10T137/7913 ,  Y10T137/7916

    摘要： A miniaturized device for producing high pressure in a fluid imposes stringent requirements on the manufacturing process.The device according to the invention consists of a hollow piston displaceably mounted in a cylinder and a valve member which is guided by the hollow piston and mounted so as to be axially movable relative to the hollow piston. The valve member is arranged at one end of the hollow piston inside or immediately in front of the end of the hollow piston.The device is used in a mechanically operated high pressure atomizer. This consists of a two part housing which comprises a pump housing with nozzle, a blocking mechanism, a spring housing with spring, a non-pressurized storage container for the fluid and a medical counter integrated in the spring housing.The valve operates without any auxiliary force, closes very rapidly and is sealed tight against high pressure. The atomizer is safe and simple to operate and environmentally friendly. The fluid is metered extremely accurately.The atomizer is used, for example, to produce an inhalable aerosol of a liquid medicament without the use of propellant gas, at 320 bar, for example.

    摘要翻译： 用于在流体中产生高压的小型化装置对制造过程施加了严格的要求。 根据本发明的装置包括可移动地安装在气缸中的中空活塞和由中空活塞引导并安装成可相对于中空活塞轴向移动的阀构件。 阀构件布置在中空活塞的一端处于中空活塞的端部的内部或紧邻中空活塞端部的前方。 该设备用于机械操作的高压雾化器。 这包括两部分壳体，其包括具有喷嘴的泵壳体，阻塞机构，具有弹簧的弹簧壳体，用于流体的非加压存储容器和集成在弹簧壳体中的医疗计数器。 阀门没有任何辅助作用力，非常快速地关闭，并在高压下密封。 雾化器操作安全，操作简单，环保。 流体测量非常准确。 例如，雾化器用于例如在320巴下产生液体药物的可吸入气溶胶，而不使用推进剂气体。

    Cartridge for a liquid
    3.
    发明授权
    Cartridge for a liquid 有权
    墨盒用于液体

    公开(公告)号：US07802568B2

    公开(公告)日：2010-09-28

    申请号：US11232896

    申请日：2005-09-23

    申请人： Joachim Eicher ,  Johannes Geser ,  Matthias Hausmann ,  Michael Schyra ,  Gilbert Wuttke ,  Andreas Fiol ,  Heinrich Kladders ,  Dieter Hochrainer ,  Bernd Zierenberg

    发明人： Joachim Eicher ,  Johannes Geser ,  Matthias Hausmann ,  Michael Schyra ,  Gilbert Wuttke ,  Andreas Fiol ,  Heinrich Kladders ,  Dieter Hochrainer ,  Bernd Zierenberg

    IPC分类号： A61M11/00 ,  A61M15/00

    CPC分类号： B05B11/0054 ,  A61M15/0065 ,  B05B11/0008 ,  B05B11/00412 ,  B05B11/0044 ,  B05B11/00444 ,  B05B11/00446

    摘要： For meteredly dispensing a liquid over a period of several months from a container which can be stored over a long period of time, the need is for a container which is practically diffusion-tight and in which the liquid does not come into contact with the ambient atmosphere. The cartridge according to the invention is a three-shell container comprising a collapsible bag which contains the liquid, a container which is stable in respect of shape and a stiff metal casing. The cartridge can be releasably connected to a dispensing device. The cartridge can be provided with a micro-opening with which the time for pressure equalisation between the cartridge and the ambient atmosphere can be adjusted. The cartridge is suitable for aqueous and for alcoholic liquids which contain a pharmaceutically active substance. The liquid in the cartridge is protected from external influences. The cartridge can be used in an atomiser for producing an inhalable aerosol for the treatment of illnesses.

    摘要翻译： 对于可以长时间储存​​的容器在几个月的时间内计量分配液体，需要一种几乎不扩散的容器，其中液体不会与环境接触 大气层。 根据本发明的墨盒是一种三壳容器，其包括容纳液体的可折叠袋，相对于形状稳定的容器和刚性金属外壳。 盒可以可释放地连接到分配装置。 墨盒可以设置有微孔，可以调节墨盒和环境大气之间的压力均衡时间。 该药筒适用于含有药物活性物质的水溶液和含酒精液体。 保护盒中的液体免受外部影响。 墨盒可用于雾化器中，用于产生用于治疗疾病的可吸入气雾剂。

    Needle-less injector of miniature type
    4.
    发明授权
    Needle-less injector of miniature type 有权

    公开(公告)号：US06689092B2

    公开(公告)日：2004-02-10

    申请号：US09797001

    申请日：2001-03-02

    申请人： Bernd Zierenberg ,  Ralph Christian Reimholz ,  Knut Elbers ,  Stefan Henke ,  Joachim Eicher ,  Johannes Geser

    发明人： Bernd Zierenberg ,  Ralph Christian Reimholz ,  Knut Elbers ,  Stefan Henke ,  Joachim Eicher ,  Johannes Geser

    IPC分类号： H61M530

    CPC分类号： A61M5/30 ,  A61M5/204 ,  A61M5/3145 ,  A61M5/31531 ,  A61M2005/3104 ,  A61M2005/3128 ,  A61M2205/7545

    摘要： Needle-less injectors for liquids are known in many different forms which are adapted to different conditions of use. The needle-less injector according to the invention is in the form of a hand-held unit. It includes a locking stressing mechanism, an energy-storing spring (36), a hollow plunger (37) displaceable in a cylinder (38) and a nozzle (39). At its one end, the hollow plunger is provided with a valve body (42). The supply container (44) for the liquid is arranged within the housing. When the locking stressing mechanism is stressed by rotation of the two housing portions (31, 32) relative to each other the hollow plunger (37) is drawn out of the cylinder (38); at the same time the amount of liquid required for an injection is conveyed out of the supply container (44) through the plunger into the pump chamber (43). After the locking stressing mechanism is triggered the amount of liquid is expelled from the pump chamber through the nozzle. The needle-less injector can be safely and easily handled, even by unskilled persons. It is used for the intracutaneous injection of a medicament-bearing liquid into biological tissue, for the injection of an active substance-bearing liquid into a plant, or for the injection of a liquid through a membrane into the space behind the membrane.

    Cartridge for a liquid
    7.
    发明申请
    Cartridge for a liquid 有权
    墨盒用于液体

    公开(公告)号：US20060016449A1

    公开(公告)日：2006-01-26

    申请号：US11232896

    申请日：2005-09-23

    申请人： Joachim Eicher ,  Johannes Geser ,  Matthias Hausmann ,  Michael Schyra ,  Gilbert Wuttke ,  Andreas Fiol ,  Heinrich Kladders ,  Dieter Hochrainer ,  Bernd Zierenberg

    发明人： Joachim Eicher ,  Johannes Geser ,  Matthias Hausmann ,  Michael Schyra ,  Gilbert Wuttke ,  Andreas Fiol ,  Heinrich Kladders ,  Dieter Hochrainer ,  Bernd Zierenberg

    IPC分类号： A61M11/00

    CPC分类号： B05B11/0054 ,  A61M15/0065 ,  B05B11/0008 ,  B05B11/00412 ,  B05B11/0044 ,  B05B11/00444 ,  B05B11/00446

    摘要： For meteredly dispensing a liquid over a period of several months from a container which can be stored over a long period of time, the need is for a container which is practically diffusion-tight and in which the liquid does not come into contact with the ambient atmosphere. The cartridge according to the invention is a three-shell container comprising a collapsible bag which contains the liquid, a container which is stable in respect of shape and a stiff metal casing. The cartridge can be releasably connected to a dispensing device. The cartridge can be provided with a micro-opening with which the time for pressure equalisation between the cartridge and the ambient atmosphere can be adjusted. The cartridge is suitable for aqueous and for alcoholic liquids which contain a pharmaceutically active substance. The liquid in the cartridge is protected from external influences. The cartridge can be used in an atomiser for producing an inhalable aerosol for the treatment of illnesses.

    摘要翻译： 对于可以长时间储存​​的容器在几个月的时间内计量分配液体，需要一种几乎不扩散的容器，其中液体不会与环境接触 大气层。 根据本发明的墨盒是一种三壳容器，其包括容纳液体的可折叠袋，相对于形状稳定的容器和刚性金属外壳。 盒可以可释放地连接到分配装置。 墨盒可以设置有微孔，可以调节墨盒和环境大气之间的压力均衡时间。 该药筒适用于含有药物活性物质的水溶液和含酒精液体。 保护盒中的液体免受外部影响。 墨盒可用于雾化器中，用于产生用于治疗疾病的可吸入气雾剂。

    Device for mounting a component exposed to a pressurized fluid
    9.
    发明授权
    Device for mounting a component exposed to a pressurized fluid 有权
    用于安装暴露于加压流体的部件的装置

    公开(公告)号：US06176442B1

    公开(公告)日：2001-01-23

    申请号：US09051205

    申请日：1998-11-12

    申请人： Joachim Eicher ,  Johannes Geser

    发明人： Joachim Eicher ,  Johannes Geser

    IPC分类号： B05B100

    CPC分类号： B05B1/00

    摘要： The mounting of a component subjected to pressure from a fluid requires special precautions if the component is made of wear resistant, hard and hence generally brittle material and may be destroyed by locally raised stresses. A fluidic component of this kind, made, for example, of silicon/glass is arranged in an elastomeric shaped component, made, for example, of silicon rubber. The inner contours of the elastomeric shaped component correspond to the outer contours of the fluidic component. The outer contours of the shaped component corresponds to the inner contours of a holder. Due to this “floating mounting” there are no unacceptable local pressure peaks and no deformation of the fluidic component. The device is particularly suitable for mounting a fluidic component made of glass or silicon, or miniature dimensions, subject to high pressure.

    摘要翻译： 如果零件由耐磨损，硬质材料制成并且因此通常是脆性材料，则受到来自流体压力的部件的安装需要特别的预防措施，并且可能被局部凸起的应力破坏。 例如由硅/玻璃制成的这种流体成分被布置在例如由硅橡胶制成的弹性体部件中。 弹性体形状部件的内部轮廓对应于流体部件的外部轮廓。 成形部件的外轮廓对应于保持器的内轮廓。 由于这种“浮动安装”，没有不可接受的局部压力峰值，并且没有流体部件的变形。 该装置特别适用于安装由玻璃或硅制成的流体组件，或微型尺寸，承受高压。

    Microstructured high pressure nozzle with built-in filter function
    10.
    发明授权
    Microstructured high pressure nozzle with built-in filter function 有权
    微结构高压喷嘴，内置过滤功能

    公开(公告)号：US07896264B2

    公开(公告)日：2011-03-01

    申请号：US10877134

    申请日：2004-06-25

    申请人： Joachim Eicher ,  Johannes Geser ,  Matthias Hausmann ,  Holger Reinecke

    发明人： Joachim Eicher ,  Johannes Geser ,  Matthias Hausmann ,  Holger Reinecke

    IPC分类号： B01D50/00

    CPC分类号： B05B1/00 ,  A61M11/06 ,  A61M15/0065 ,  A61M2205/0244 ,  B05B15/40

    摘要： A microstructured nozzle consists of a number of channels produced by microstructuring a plate-shaped member. In the nozzle the channels are located between projections which are arranged side by side in rows and project from a base plate. This microstructured base plate is covered with a cover plate. The channels are narrowly defined in terms of shape, cross sectional area and length. The nozzle contains a filter as the primary structure and a secondary structure downstream of the filter.The nozzle is used, for example, with an atomiser which produces an aerosol from a fluid containing a medicament.

    摘要翻译： 微结构喷嘴由通过微结构化板状构件产生的多个通道组成。 在喷嘴中，通道位于并排排列并从基板突出的突起之间。 该微结构基板用盖板覆盖。 通道在形状，横截面面积和长度方面被狭义地定义。 喷嘴包含作为主要结构的过滤器和过滤器下游的二级结构。 喷嘴例如使用从含有药物的流体产生气溶胶的雾化器使用。