利索-全球专利检索

  1. 登录
  2. 注册

搜索结果

9 条记录 (耗时 0.021 秒)

    Ultraphobic surface having a multitude of reversibly producible hydrophilic and/or oleophilic areas
    2.
    发明申请
    Ultraphobic surface having a multitude of reversibly producible hydrophilic and/or oleophilic areas 审中-公开
    具有多个可逆生产的亲水和/或亲油区域的超疏水表面

    公开(公告)号：US20060013735A1

    公开(公告)日：2006-01-19

    申请号：US10505632

    申请日：2003-02-24

    申请人： Joachim Engelking ,  Karsten Reihs ,  Eckhard Nordhoff ,  Martin Muller

    发明人： Joachim Engelking ,  Karsten Reihs ,  Eckhard Nordhoff ,  Martin Muller

    IPC分类号： B01L3/00

    CPC分类号： H01J49/04 ,  B01J2219/00527 ,  B01L3/5085 ,  B01L3/5088 ,  B01L2300/0819 ,  B01L2300/165 ,  B01L2300/166 ,  B08B17/065 ,  C12Q1/6837 ,  G01N1/22 ,  C12Q2565/627

    摘要： The invention relates to a planar structure, particularly a plate, having an ultraphobic surface on which the hydrophilic and/or oleophilic areas can be reversibly produced. The invention also relates to a planar structure comprising an ultraphobic surface provided with hydrophilic and/or oleophilic areas that are each completely surrounded by ultraphobic areas. The invention additionally relates to methods for reversibly producing hydrophilic and/or oleophilic areas on ultraphobic surfaces, to the deposition of liquid drops onto the inventive planar structure, and to the use of the inventive planar structure for conducting mass spectroscopic and/or optical analysis of aqueous liquids.

    摘要翻译： 本发明涉及具有超疏水表面的平面结构，特别是平板结构，亲水和/或亲油区域可以在其上可逆地产生。 本发明还涉及一种平面结构，其包括具有亲水和/或亲油区域的超疏水表面，每个区域都被超疏水区域完全包围。 本发明还涉及用于在超疏水表面上可逆地产生亲水和/或亲油区域，将液滴沉积到本发明的平面结构上的方法，以及使用本发明的平面结构进行质谱分析和/或光学分析 含水液体。

    Processing proteins from gels for analysis using mass spectrometry
    5.
    发明授权
    Processing proteins from gels for analysis using mass spectrometry 有权
    使用质谱法处理凝胶蛋白进行分析

    公开(公告)号：US06627410B2

    公开(公告)日：2003-09-30

    申请号：US09829402

    申请日：2001-04-09

    申请人： Eckhard Nordhoff ,  Helmut Meyer ,  Martin Schurenberg

    发明人： Eckhard Nordhoff ,  Helmut Meyer ,  Martin Schurenberg

    IPC分类号： C12Q137

    CPC分类号： B01L3/5085 ,  G01N27/44717

    摘要： The invention relates to methods and devices used for digesting small amounts of protein in tiny cut gel pieces and for extracting the peptides resulting from the digestion in preparation for analysis by mass spectrometry. The invention involves digesting proteins using enzymes within the gel pieces in vessels which have permeable but lyophobic bases in such a manner that they scarcely touch the walls of the vessel, and then rapidly removing the digested proteins from the gel pieces almost completely by gentle centrifuging. It is then advantageous to bond the peptides reversibly to suitable surfaces as quickly as possible. For this purpose, the bases of the vessels may contain structures for bonding the peptides which are suitable for washing and subsequently eluting the peptides. A number of vessels can be combined together to form plates which, for example, can have the size of microtiter plates.

    摘要翻译： 本发明涉及用于在微小切片凝胶片中消化少量蛋白质的方法和装置，并用于提取由消化产生的肽以准备通过质谱法进行分析。本发明涉及使用在血管内的凝胶片段内的酶来消化蛋白质 具有可渗透但疏水的碱，使得它们几乎不接触血管的壁，然后通过温和离心几乎完全快速地从凝胶片中除去消化的蛋白质。 因此，尽可能快地将肽可逆地结合到合适的表面是有利的。 为此目的，容器的碱基可以包含用于结合适于洗涤和随后洗脱肽的肽的结构。 可以将多个容器组合在一起以形成例如可以具有微量滴定板尺寸的板。

    Method and devices for depositing samples on an electrically shielded substrat
    6.
    发明授权
    Method and devices for depositing samples on an electrically shielded substrat 有权
    用于在电屏蔽衬底上沉积样品的方法和装置

    公开(公告)号：US08614100B2

    公开(公告)日：2013-12-24

    申请号：US10576644

    申请日：2004-10-20

    申请人： Eckhard Nordhoff ,  Alan Bullock ,  Christine Lubbert ,  Antonin Schenk ,  Holger Eickhoff ,  Martin Horn

    发明人： Eckhard Nordhoff ,  Alan Bullock ,  Christine Lubbert ,  Antonin Schenk ,  Holger Eickhoff ,  Martin Horn

    IPC分类号： G01N1/10

    CPC分类号： B01L3/0268 ,  B01J2219/00315 ,  B01J2219/00378 ,  B01J2219/00662 ,  B01L3/5085 ,  B01L2300/06 ,  B01L2300/0636 ,  B01L2300/0829 ,  B01L2400/0415 ,  C40B60/14 ,  Y10T436/119163 ,  Y10T436/2575

    摘要： A method for depositing samples, in which at least one sample (10) is arranged on a substrate (30), comprises the following steps: positioning a sample dispenser (20) above the substrate (30), and actuating the sample dispenser (20) so that the sample (10) is moved from the sample dispenser (20) along a trajectory (11) to a predefined deposition position (32) on the substrate (30), wherein at least part of the trajectory (11) is shielded against electrical interference fields. Also described is a substrate (30) for receiving samples (10), comprising a substrate body (31), on the surface of which at least one deposition position (32) is provided, and a shielding electrode (40), which is designed so as to electrostatically shield the space above the at least one deposition position (32) against electrical interference fields.

    摘要翻译： 一种用于沉积样品的方法，其中至少一个样品（10）布置在基底（30）上，包括以下步骤：将样品分配器（20）定位在基底（30）上方，并致动样品分配器（20） ），使得样品（10）沿着轨迹（11）从样品分配器（20）移动到基底（30）上的预定沉积位置（32），其中轨迹（11）的至少一部分被屏蔽 针对电气干扰场。 还描述了一种用于接收样品（10）的基板（30），其包括基板主体（31），其表面上设置有至少一个沉积位置（32）和屏蔽电极（40），其被设计 以便对所述至少一个沉积位置（32）上方的空间进行静电屏蔽以抵抗电干扰场。