Sialic carbohydrates
    4.
    发明申请
    Sialic carbohydrates 审中-公开
    唾液碳水化合物

    公开(公告)号:US20050070464A1

    公开(公告)日:2005-03-31

    申请号:US10502049

    申请日:2003-01-31

    摘要: The invention relates to the use of sialic carbohydrates of general formula (I), containing at least one carbohydrate unit of general formula (II) for the immune modulation, immune suppression and in the prevention and treatment of infections in humans and animals. In said formula (II), Sia represents a sialic acid or a sialic acid derivative in an α2-3 bond, Gal represents a galactose-monosaccharide-unit, HexNac represents an N-acetylated galactosamine or glucosamine-monosaccharide-unit (GalNAc or GlcNAc), Hex represents a galactose- or glucose-monosaccharide-unit (Gal or Glc), C represents HexNac or Hex or is absent, n represents 1-50, V represents OH, a carbohydrate radical or a connecting point on a support T, with the proviso that if V represents OH, n represents 1, and if V represents a carbohydrate radical or a support T, n represents the number of carbohydrate unites of general formula (II) directly connected to said carbohydrate radical or support, X represents a sialic acid or a sialic acid derivative, wherein a second sialic acid or a sialic acid derivative or more sialic acid or sialic acid derivatives can be connected to an α2-8 bond, a phosphate, a sulphate, or carboxyl-group or a monosaccharide having a phosphate, sulphate, or carboxyl group and only one of the radicals X is present.

    摘要翻译: 本发明涉及含有至少一种通式(II)的碳水化合物单元的通式(I)的唾液酸碳水化合物用于免疫调节,免疫抑制和预防和治疗人和动物感染的用途。 在所述式(II)中,Sia表示α2-3键中的唾液酸或唾液酸衍生物,Gal表示半乳糖 - 单糖单元,HexNac表示N-乙酰化的半乳糖胺或葡糖胺单糖单元(GalNAc或GlcNAc ),Hex表示半乳糖或葡萄糖单糖单元(Gal或Glc),C表示HexNac或Hex或不存在,n表示1-50,V表示OH,碳水化合物基团或载体T上的连接点, 条件是如果V表示OH,n表示1,并且如果V表示碳水化合物基团或载体T,则n表示与所述碳水化合物基团或载体直接连接的通式(II)的碳水化合物单元的数目,X表示 唾液酸或唾液酸衍生物,其中第二唾液酸或唾液酸衍生物或更多的唾液酸或唾液酸衍生物可以连接到α2-8键,磷酸盐,硫酸盐或羧基或单糖上,其具有 磷酸盐,硫酸盐, 或羧基,并且仅存在基团X中的一个。

    Nutrition containing fat blend
    5.
    发明授权
    Nutrition containing fat blend 有权
    营养含脂肪混合物

    公开(公告)号:US08729123B2

    公开(公告)日:2014-05-20

    申请号:US13251399

    申请日:2011-10-03

    IPC分类号: A61K31/22 A61K31/20

    摘要: The invention relates to the use of long chain polyunsaturated fatty acids for the manufacture of a nutritional composition for feeding infants of a mother who suffered from a metabolic disorder during pregnancy and to a corresponding composition. Said composition comprises a n-3 polyunsaturated fatty acid fraction containing at least 0.1 wt % docosahexaenoic acid (DHA) based on total weight of the lipid, at least 0.01 wt % n-3 docosapentaenoic acid (DPAn-3) based on total weight of the lipid, and at least 0.01 wt. % eicosapentaenoic acid (EPA) based on total weight of the lipid, wherein the sum of DHA, DPAn-3 and EPA is below 1 wt. % of total lipid.

    摘要翻译: 本发明涉及长链多不饱和脂肪酸用于制造用于喂养怀孕期间代谢紊乱的母亲的婴儿的营养组合物和相应组合物的用途。 所述组合物包含n-3多不饱和脂肪酸级分,其含有基于脂质总重量的至少0.1重量%二十二碳六烯酸(DHA),至少0.01重量%的n-3二十二碳五烯酸(DPAn-3),基于 脂质和至少0.01重量% 基于脂质总重量的二十碳五烯酸(EPA),其中DHA,DPAn-3和EPA的总和低于1wt。 总脂质的百分比。

    Antiadhesive carbohydrates
    6.
    发明授权
    Antiadhesive carbohydrates 有权
    防粘碳水化合物

    公开(公告)号:US07919479B2

    公开(公告)日:2011-04-05

    申请号:US11511500

    申请日:2006-08-29

    摘要: Provided is a pharmaceutical or dietetic product, which serves for reducing and/or blocking the adhesion of pathogenic substances and organisms to eucaryontic cells, in particular mammal cells. Said preparation contains at least one carbohydrate having an uronic acid unit on one of the ends thereof. 10 to 100% of the present, terminal uronic acid units pertaining to the carbohydrates are provided with a double bond that is especially situated between the C4 and C5 atom.

    摘要翻译: 提供了一种药物或饮食产品,其用于减少和/或阻断致病物质和生物体对真核细胞特别是哺乳动物细胞的粘附。 所述制剂包含至少一种在其一个端部具有糖醛酸单元的碳水化合物。 本发明的碳原子数为10〜100%的末端糖醛酸单元具有特别位于C4和C5原子之间的双键。

    Electrical contact element for contacting an electrical component under test and contacting apparatus
    7.
    发明授权
    Electrical contact element for contacting an electrical component under test and contacting apparatus 有权
    用于接触被测电气部件和接触装置的电接触元件

    公开(公告)号:US07850460B2

    公开(公告)日:2010-12-14

    申请号:US12463083

    申请日:2009-05-08

    IPC分类号: H01R12/00

    摘要: An elongate electrical contact element (1) for physically contacting electrical components under test, having two electrical contacting end regions (2, 3) and an elongate intermediate region (4) situated between the end regions (2, 3). The intermediate region (4) has an essentially rectangular cross-section and is configured lamellar along its longitudinal extent. Also disclosed is a corresponding contacting apparatus (22) including such a contact element (1) and a contact element holder (23).

    摘要翻译: 用于物理接触待测电气部件的细长电接触元件(1),具有两个电接触端区域(2,3)和位于端部区域(2,3)之间的细长中间区域(4)。 中间区域(4)具有基本上矩形的横截面,并且沿其纵向范围被构造成层状。 还公开了包括这种接触元件(1)和接触元件保持器(23)的相应接触装置(22)。

    Food for diabetics
    8.
    发明授权
    Food for diabetics 失效
    糖尿病食物

    公开(公告)号:US07498318B1

    公开(公告)日:2009-03-03

    申请号:US10129095

    申请日:2000-11-10

    IPC分类号: A61K31/718

    摘要: Provided is a carbohydrate mixture comprising at least one modified carbohydrate from a base body and a carbohydrate residue coupled therewith. The base body concerned is either a digestible glucose-containing carbohydrate in the form of a digestible glucan or a non-digestible reserve carbohydrate, skeletal carbohydrate or a low-molecular component thereof. By coupling the base body with a carbohydrate residue, the glucose release from the inventive carbohydrate mixture is reduced by at least 10%, determined in an in-vivo digestion system on the basis of pancreatine and compared with a carbohydrate mixture containing the same amount by weight of non-modified carbohydrates. By means of the inventive carbohydrate mixture, the postprandial blood glucose concentration after eating can be moderated. The glucose can thus be metabolized by diabetics in spite of the existing lack of insulin. The inventive carbohydrate mixtures can be used in food for diabetics and in pharmaceuticals.

    摘要翻译: 提供了包含至少一种来自碱体的修饰的碳水化合物和与其偶联的碳水化合物残基的碳水化合物混合物。 所涉及的基体是可消化葡萄糖或不可消化的储备碳水化合物,骨骼碳水化合物或其低分子组分形式的可消化的含葡萄糖的碳水化合物。 通过将基体与碳水化合物残基偶联,将本发明的碳水化合物混合物的葡萄糖释放量减少至少10%,在基于胰腺的体内消化系统中测定,并与含有相同量的碳水化合物混合物 非改性碳水化合物的重量。 通过本发明的碳水化合物混合物,饮食后餐后血糖浓度可以缓和。 糖可以由糖尿病代谢,尽管目前缺乏胰岛素。 本发明的碳水化合物混合物可用于糖尿病患者和药物中。