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1.发明授权Device for implanting a row of radioactive seeds and non-radioactive spacers in an animal body 有权用于在动物体内植入一排放射性种子和非放射性隔离物的装置公开(公告)号：US07288061B2
公开(公告)日：2007-10-30
申请号：US10674356
申请日：2003-10-01
IPC分类号： A61N5/00
CPC分类号： A61N5/1007 , A61N2005/1011 , A61N2005/1023
摘要： A device for implanting radioactive seeds and non-radioactive spacers in a desired configuration in an animal body for effecting radiation therapy. An elongated hollow needle is inserted in the body. A pushing element implants the row of seeds and spacers though the hollow needle towards the desired location. A tube shaped element receives the row of seeds and spacers. A lube shaped sleeve having open ends is used to insert the tube shaped element through the needle and toward the location. The pushing elements pushes the row of seeds and spacers into the desired location while still being carried in the tube shaped element.
摘要翻译： 用于在动物体内植入放射性种子和非放射性间隔物的装置，用于实现放射治疗。 细长的中空针插入体内。 推动元件通过中空针将所述种子和间隔物排排列到期望的位置。 管形元件接收一排种子和间隔物。 使用具有开口端的润滑脂套筒将管形元件穿过针头并朝向该位置。 推动元件将种子和间隔物排推入期望的位置，同时仍被携带在管状元件中。
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2.发明授权Apparatus and method for effecting radiation treatment on a pre-selected anatomical portion of an animal body 有权对动物体的预先选择的解剖部分进行放射治疗的装置和方法公开(公告)号：US09387343B2
公开(公告)日：2016-07-12
申请号：US13367807
申请日：2012-02-07
IPC分类号： A61N5/10
CPC分类号： A61N5/1007 , A61N5/1075 , A61N2005/1008 , A61N2005/1012 , A61N2005/1094
摘要： A medical apparatus for effecting radiation treatment on a pre-selected anatomical portion of an animal body is disclosed. The medical apparatus may include a plurality of treatment channels configured to be positioned adjacent a body tissue and a plurality of delivery channels coupled to a corresponding number of treatment channels. The medical apparatus may also include a plurality of source channels configured to receive one or more energy sources, a tracking channel configured to receive a tracking element, and a connecting element configured to connect each delivery channel with either one of the plurality of sources channels or the tracking channel.
摘要翻译： 公开了一种用于对动物体的预先选择的解剖部分进行放射治疗的医疗装置。 医疗设备可以包括被配置为邻近身体组织定位的多个治疗通道以及耦合到相应数量的治疗通道的多个输送通道。 医疗设备还可以包括被配置为接收一个或多个能量源的多个源通道，被配置为接收跟踪元件的跟踪通道，以及被配置为将每个输送通道与多个源通道中的任一个连接的连接元件 跟踪通道。
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公开(公告)号：US07507197B2
公开(公告)日：2009-03-24
申请号：US10615844
申请日：2003-07-10
IPC分类号： A61N5/00
CPC分类号： A61B18/1485 , A61B18/1477 , A61B2017/00274 , A61B2018/00547 , A61B2018/1425 , A61N5/1007 , A61N2005/1011
摘要： A device for effecting radiation treatment of benign or malign prostate hyperplasia. The device includes a catheter probe having an elongated body with a circumferential surface which is inserted within the urethra towards the prostate. The elongated body has a longitudinal bore extending towards at least one outlet opening present in the circumferential surface near the proximal end. A catheter tube is inserted with a proximal sharp end through the longitudinal bore of the elongated body, with an outlet opening and through the urethral wall towards a desired location within the prostate. A pre-planned amount of radiation is delivered via the catheter tube at a location within the prostate for effecting the radiation treatment. The urethral insertion probe allows a quick and accurate positioning of the catheter probe and the catheter tube relative to the prostate without discomforting the patient. The catheter probe is movably accommodated within the urethral probe.
摘要翻译： 用于进行良性或恶性前列腺增生的放射治疗的装置。 该装置包括具有细长主体的导管探针，其具有朝向前列腺插入尿道内的圆周表面。 细长主体具有朝向近端附近的圆周表面中存在的至少一个出口开口延伸的纵向孔。 导管管插入具有通过细长体的纵向孔的近端尖端，具有出口开口并穿过尿道壁朝向前列腺内的期望位置。 预先计划的辐射量通过前列腺内的一个位置处的导管传送，以进行放射治疗。 尿道插入探针允许导管探针和导管相对于前列腺的快速和准确的定位，而不会使患者不舒服。 导管探针可移动地容纳在尿道探针内。
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4.发明申请APPARATUS AND METHOD FOR EFFECTING RADIATION TREATMENT ON A PRE-SELECTED ANATOMICAL PORTION OF AN ANIMAL BODY 有权用于对动物身体的选择性解剖部位进行辐射治疗的装置和方法公开(公告)号：US20120215052A1
公开(公告)日：2012-08-23
申请号：US13367807
申请日：2012-02-07
IPC分类号： A61N5/00
CPC分类号： A61N5/1007 , A61N5/1075 , A61N2005/1008 , A61N2005/1012 , A61N2005/1094
摘要： A medical apparatus for effecting radiation treatment on a pre-selected anatomical portion of an animal body is disclosed. The medical apparatus may include a plurality of treatment channels configured to be positioned adjacent a body tissue and a plurality of delivery channels coupled to a corresponding number of treatment channels. The medical apparatus may also include a plurality of source channels configured to receive one or more energy sources, a tracking channel configured to receive a tracking element, and a connecting element configured to connect each delivery channel with either one of the plurality of sources channels or the tracking channel.
摘要翻译： 公开了一种用于对动物体的预先选择的解剖部分进行放射治疗的医疗装置。 医疗设备可以包括被配置为邻近身体组织定位的多个治疗通道以及耦合到相应数量的治疗通道的多个输送通道。 医疗设备还可以包括被配置为接收一个或多个能量源的多个源通道，被配置为接收跟踪元件的跟踪通道，以及被配置为将每个输送通道与多个源通道中的任一个连接的连接元件 跟踪通道。
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公开(公告)号：US06641519B1
公开(公告)日：2003-11-04
申请号：US09788265
申请日：2001-02-16
IPC分类号： A61M3600
CPC分类号： A61N5/1007 , A61N2005/1008
摘要： A drive device in a medical device for driving a wire through a guide tube from a first position with an end of the wire outside an animal body to a second position in which the end is inside the animal body. The drive device comprises first and second elements rotatable relative to each other. The first and second elements each have contact surfaces, that in each rotational position of the first and second elements relative to each other are in contact with each other in a contact area along a common contact plane. A storage space going about the axis is provided for the wire in the first element. The storage space is open along a length of it to the contact surface of the first element. The second element comprises a channel for the wire and is open to the contact plane.
摘要翻译： 一种医疗装置中的驱动装置，用于通过引导管从第一位置驱动电线，其中电线的端部在动物体外部延伸到第二位置，其中端部在动物体内。 驱动装置包括可相对于彼此旋转的第一和第二元件。 第一和第二元件各自具有接触表面，在第一和第二元件的相对于彼此的每个旋转位置中，沿着公共接触平面的接触区域中彼此接触。 为第一个元件中的导线提供围绕轴线的存储空间。 存储空间沿其长度打开到第一元件的接触表面。 第二元件包括用于导线的通道并且对接触平面开放。
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公开(公告)号：US06595908B2
公开(公告)日：2003-07-22
申请号：US09788226
申请日：2001-02-16
IPC分类号： A61M3600
CPC分类号： A61N5/1007 , A61N5/1027 , A61N2005/1008 , A61N2005/1009 , A61N2005/1011
摘要： A modular device for implanting radioactive seeds in an animal body through needles implanted in the body. Trains of radioactive seeds and non-radioactive spacers are assembled in an assembly unit. The assembly unit comprises a device for determining activity of the seeds with an accuracy that allows distinguishing between different activities within tolerance ranges of specified nominal activities for the seeds. After implantation of the seeds in the body a pre-plan may be recalculated taking into consideration actual activities of seeds implanted. Not correctly composed trains may be disposed of. A post-plan may be determined based upon actually measured activities of implanted seeds.
摘要翻译： 用于通过植入体内的针将放射性种子植入动物体内的模块化装置。 放射性种子和非放射性隔离物的火车组装在组装单元中。 组装单元包括用于以准确度确定种子的活动的装置，其允许区分种子指定的标称活动的容许范围内的不同活动。 将种子植入体内后，可以考虑植入种子的实际活动来重新计算预先计划。 不正确组合的火车可能会被处置。 可以基于实际测量的植入种子的活动来确定后期计划。
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7.发明授权After loader apparatus as well as a device for exchanging an after loader cartridge 失效装载机装置以及用于更换后装载机筒的装置公开(公告)号：US07097609B2
公开(公告)日：2006-08-29
申请号：US10382511
申请日：2003-03-07
CPC分类号： G21F5/015 , A61N5/1007 , A61N2005/1008
摘要： The invention relates to an after loader apparatus for treatment of tumours in an animal body comprising a housing with at least one exchangeable radiation source connected to a first end of a transport wire, which wire is connected with its other end to transport means for advancing said transport wire and said radiation source through a guide tube to and from a tumour in said body, where at least the radiation source and the transport wire are mounted in an exchangeable radiation shielded after loader cartridge, which cartridge can be placed in a suitable receptable opening present in said housing.It is an object of the invention to provide an after loader apparatus wherein in a more safe manner to the environment a cartridge containing a radioactive source can be replaced by another cartridge containing a new radioactive source and according to the invention the after loader apparatus is characterized in that, for exchanging said radiation source after use an exchanging device is present for, in a first step, removing the cartridge with the used radiation source from said receptable opening and, in a second step, inserting a further cartridge containing a new radiation source in said receptable opening.The invention relates furthermore to a device for exchanging an after loader cartridge in an after loader apparatus according to the invention.
摘要翻译： 本发明涉及一种用于治疗动物体内的肿瘤的后装载装置，包括具有连接到输送线的第一端的至少一个可交换辐射源的壳体，该导线与其另一端连接到用于推进所述 输送线和所述辐射源通过导管连接到所述主体中的肿瘤，其中至少辐射源和输送线被安装在装载器盒之后屏蔽的可更换辐射中，所述可插入的辐射源可以放置在合适的可接收开口 存在于房屋内。 本发明的目的是提供一种后装载装置，其中以更安全的方式到达环境中，容纳放射源的筒可以被另一个包含新的放射源的筒代替，根据本发明，后装载装置的特征在于 其特征在于，为了在使用之后交换所述辐射源，存在交换装置，用于在第一步骤中用所述可接收的开口用所使用的辐射源去除所述盒，并且在第二步骤中，插入另外的包含新的辐射源的盒 在所述可接收的开口中。 本发明还涉及根据本发明的用于在后装载机装置中更换后装载机筒的装置。
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公开(公告)号：US09623261B2
公开(公告)日：2017-04-18
申请号：US13262629
申请日：2010-03-22
CPC分类号： A61N5/1016 , A61B17/4241 , A61B90/11 , A61B2017/3411 , A61M25/01 , A61M37/00 , A61N5/1027 , A61N2005/1008 , A61N2005/1012 , A61N2005/1018
摘要： The invention relates to an assembly for performing brachytherapy treatment of tumor tissue in a human or animal body comprising an intracavitary component and at least one guiding unit, said at least one guiding unit exhibiting a longitudinal axis and being connectable to said intracavitary component, and wherein said at least one guiding unit is provided with coupling means for coupling at least one interstitial needle-assembly for delivering treatment to said tumor tissue. The assembly has coupling/uncoupling means arranged to allow a displacement of said at least one interstitial needle-assembly in a direction transverse to said longitudinal axis and to prevent a displacement of said at least one interstitial needle-assembly in a direction parallel to or a pre-defined angle to said longitudinal axis. This coupling principle allows for the preparation of the guiding unit before the patient is being hospitalized and positioned in the treatment room and will prevent the unwanted uncoupling of the interstitial needle-assembly during the actual treatment being performed, further reducing the risk of adversely affected treatment parameters (location and duration of the radiation being administered to the patient).
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9.发明授权Capsule for use in brachytherapy and a combination of a capsule for brachytherapy and a guidewire 有权用于近距离放射治疗的胶囊和用于近距离放射治疗的胶囊和导丝的组合公开(公告)号：US06179768B2
公开(公告)日：2001-01-30
申请号：US09214428
申请日：1999-03-03
IPC分类号： A61M3600
CPC分类号： A61N5/1002 , A61N2005/1025
摘要： A capsule for taking up at least one radioactive source for application in brachytherapy and to be connected to a guidewire, the capsule having a cylindrical mantle that can be closed on the proximal end by a coupling element, and the capsule having a rounded top section at its distal end, the mantle and the inner surface of the top section defining a substantially straight circular-cylindrical cavity, in which the operation at least one radioactive source is placed, the inner surface of the top section, at least in a peripheral area thereof, being curved in distal direction and the cavity continuing somewhat in the top section, and the end of that least one radioactive source, which is located near the inner surface of the top section, is finished in a complementary curved fashion.
摘要翻译： 一种用于吸收至少一个放射源以用于近距离放射治疗并且连接到导丝的胶囊，所述胶囊具有可通过联接元件在近端封闭的圆柱形罩，并且所述胶囊具有圆形顶部， 其顶端，地幔和顶部的内表面限定基本上直的圆柱形空腔，其中放置至少一个放射源的操作，顶部的内表面至少在其周边区域中 ，在远端方向上弯曲并且空腔在顶部部分中稍微延伸，并且位于顶部部分的内表面附近的至少一个放射源的端部以互补的弯曲方式完成。
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公开(公告)号：US09132282B2
公开(公告)日：2015-09-15
申请号：US13807552
申请日：2011-06-30
申请人： René Gerard Willem Mäkel , Pieter Morssink , Hendrik Steller , Arie Luite Visscher , Cor Van De Wardt , Franciscus Antonius Maria Kuipers
发明人： René Gerard Willem Mäkel , Pieter Morssink , Hendrik Steller , Arie Luite Visscher , Cor Van De Wardt , Franciscus Antonius Maria Kuipers
IPC分类号： A61N5/10
CPC分类号： A61N5/1014 , A61N5/1016 , A61N2005/1094
摘要： The invention relates to a brachytherapy applicator device for insertion in a body cavity. The applicator device comprises an applicator shaped for insertion in the body cavity; the applicator comprising connectable segments; at least one connectable part having a form following wall surface shaped to follow the body cavity, the wall surface having a multichannel groove structure, so as to guide a plurality of catheters along the grooves in the groove structure along the wall surface.
摘要翻译： 本发明涉及一种用于插入体腔中的近距离放射线治疗装置。 涂抹器装置包括一个成形用于插入体腔内的涂抹器; 所述施加器包括可连接段; 至少一个可连接部件，其具有形成为跟随所述体腔的形状的壁后表面，所述壁表面具有多通道槽结构，以沿着所述壁表面沿着所述凹槽结构中的凹槽引导多个导管。
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