摘要:
Indoles having aryloxyalkanoic acid substituents or arylalkanoic acid substituents are agonists or partial agonists of PPAR gamma and are useful in the treatment and control of hyperglycemia that is symptomatic of type II diabetes, as well as dyslipidemia, hyperlipidemia, hypercholesterolemia, hypertriglyceridemia, and obesity that are often associated with type 2 diabetes.
摘要:
Indoles having aryloxyalkanoic acid substituents or arylalkanoic acid substituents are agonists or partial agonists of PPAR gamma and are useful in the treatment and control of hyperglycemia that is symptomatic of type II diabetes, as well as dyslipidemia, hyperlipidemia, hypercholesterolemia, hypertriglyceridemia, and obesity that are often associated with type 2 diabetes.
摘要:
Disclosed herein is a compound of formula (I), or a pharmaceutically acceptable salt thereof: (Formula (I)). Also disclosed herein are uses of a compound disclosed herein in the potential treatment or prevention of an IDO-associated disease or disorder. Also disclosed herein are compositions comprising a compound disclosed herein. Further disclosed herein are uses of a composition in the potential treatment or prevention of an IDO-associated disease or disorder.
摘要:
The present invention discloses a method and a system for transmitting data using the collaborative multiple input multiple output (MIMO) beamforming. The method comprises: selecting an MIMO mode according to channel quality information (CQI) (S502); performing the MIMO encoding on a data stream according to the selected MIMO mode, and distributing the encoded data stream to a plurality of transmitting ends which are mutual collaborative (S504); and transmitting, by the plurality of transmitting ends, the encoded data stream (S506). The present invention solves the problem in the relevant art of reducing the system performance and the flexibility, which is caused by adopting the fixed MIMO mode when the system carries out the encoding and the transmission, which is capable of improving the system performance.
摘要:
The present invention relates to compounds of formula (I) that are useful as hepatitis C virus (HCV) NS5A inhibitors, the synthesis of such compounds, and the use of such compounds for inhibiting HCV NS5A activity, for treating or preventing HCV infections and for inhibiting HCV viral replication and/or viral production in a cell-based system.
摘要:
The invention is directed to compounds for selectively inhibiting glycosidases, uses of the compounds and pharmaceutical compositions including the compounds, and methods of treating diseases and disorders related to deficiency or overexpression of O-GlcNAcase, and/or accumulation or deficiency of O-GlcNAc.
摘要:
The invention provides compounds for selectively inhibiting glycosidases, prodrugs of the compounds, and pharmaceutical compositions including the compounds or prodrugs of the compounds. The invention also provides methods of treating diseases and disorders related to deficiency or overexpression of O-GlcNAcase, accumulation or deficiency of O-GlcNAc.
摘要:
The present invention provides techniques for use in measuring effects of social sharing, and social sharing user characteristics, on advertisement effectiveness. Measurement information can be used in many ways, such as in optimizing advertisement campaigns and advertisement targeting. Techniques are provided in which bucket testing experiments are utilized. Advertisement performance may be tracked, including downstream advertisement performance, which may follow social sharing, in measuring differences in advertisement performance between content sharing users and content non-sharing users. Techniques are provided in which user social graph information may be used in determining downstream advertisement performance, even without information regarding specific sharing instances.