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公开(公告)号:US08198449B2
公开(公告)日:2012-06-12
申请号:US12549983
申请日:2009-08-28
申请人: Richard Pracitto , John F. Kadow , John A. Bender , Brett R. Beno , Katharine A. Grant-Young , Ying Han , Piyasena Hewawasam , Andrew Nickel , Kyle E. Parcella , Kap-Sun Yeung , Louis S. Chupak
发明人: Richard Pracitto , John F. Kadow , John A. Bender , Brett R. Beno , Katharine A. Grant-Young , Ying Han , Piyasena Hewawasam , Andrew Nickel , Kyle E. Parcella , Kap-Sun Yeung , Louis S. Chupak
IPC分类号: A61K31/437 , C07D471/04
CPC分类号: C07D471/04 , C07D209/42 , C07D333/68 , C07D491/048
摘要: The disclosure provides compounds of formula I, II, III, IV, and V, including their salts, as well as compositions and methods of using the compounds. The compounds have activity against hepatitis C virus (HCV) and may be useful in treating those infected with HCV.
摘要翻译: 本公开提供式I,II,III,IV和V的化合物,包括它们的盐,以及使用该化合物的组合物和方法。 该化合物具有抗丙型肝炎病毒(HCV)的活性,可用于治疗HCV感染者。
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公开(公告)号:US20100184800A1
公开(公告)日:2010-07-22
申请号:US12720182
申请日:2010-03-09
申请人: Richard Pracitto , John F. Kadow , John A. Bender , Brett R. Beno , Katharine A. Grant-Young , Ying Han , Piyasena Hewawasam , Andrew Nickel , Kyle E. Parcella , Kap-Sun Yeung , Louis S. Chupak
发明人: Richard Pracitto , John F. Kadow , John A. Bender , Brett R. Beno , Katharine A. Grant-Young , Ying Han , Piyasena Hewawasam , Andrew Nickel , Kyle E. Parcella , Kap-Sun Yeung , Louis S. Chupak
IPC分类号: A61K31/437 , C07D471/04 , A61P31/14
CPC分类号: C07D209/42 , C07D333/68 , C07D471/04 , C07D491/048
摘要: The disclosure provides compounds of formula I, II, III, IV, and V, including their salts, as well as compositions and methods of using the compounds. The compounds have activity against hepatitis C virus (HCV) and may be useful in treating those infected with HCV.
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公开(公告)号:US20100063068A1
公开(公告)日:2010-03-11
申请号:US12549983
申请日:2009-08-28
申请人: Richard Pracitto , John F. Kadow , John A. Bender , Brett R. Beno , Katharine A. Grant-Young , Ying Han , Piyasena Hewawasam , Andrew Nickel , Kyle E. Parcella , Kap-Sun Yeung , Louis S. Chupak
发明人: Richard Pracitto , John F. Kadow , John A. Bender , Brett R. Beno , Katharine A. Grant-Young , Ying Han , Piyasena Hewawasam , Andrew Nickel , Kyle E. Parcella , Kap-Sun Yeung , Louis S. Chupak
IPC分类号: A61K31/506 , C07D471/02 , A61K31/437 , C07D491/048 , C07D333/00 , A61K31/38 , A61K31/40 , C07D209/42
CPC分类号: C07D471/04 , C07D209/42 , C07D333/68 , C07D491/048
摘要: The disclosure provides compounds of formula I, II, III, IV, and V, including their salts, as well as compositions and methods of using the compounds. The compounds have activity against hepatitis C virus (HCV) and may be useful in treating those infected with HCV.
摘要翻译: 本公开提供式I,II,III,IV和V的化合物,包括它们的盐,以及使用该化合物的组合物和方法。 该化合物具有抗丙型肝炎病毒(HCV)的活性,可用于治疗HCV感染者。
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公开(公告)号:US08324212B2
公开(公告)日:2012-12-04
申请号:US13031777
申请日:2011-02-22
申请人: John F. Kadow , Richard Pracitto
发明人: John F. Kadow , Richard Pracitto
IPC分类号: A61K31/50 , C07D487/00
CPC分类号: C07D487/04
摘要: The disclosure provides compounds of formula I, including their salts, as well as compositions and methods of using the compounds. The compounds have activity against hepatitis C virus (HCV) and may be useful in treating those infected with HCV.
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公开(公告)号:US20120232099A1
公开(公告)日:2012-09-13
申请号:US13470727
申请日:2012-05-14
申请人: Richard Pracitto , John F. Kadow , John A. Bender , Brett R. Beno , Katherine A. Grant-Young , Ying Han , Piyasena Hewawasam , Andrew Nickel , Kyle E. Parcella , Kap-Sun Yeung , Louis S. Chupak
发明人: Richard Pracitto , John F. Kadow , John A. Bender , Brett R. Beno , Katherine A. Grant-Young , Ying Han , Piyasena Hewawasam , Andrew Nickel , Kyle E. Parcella , Kap-Sun Yeung , Louis S. Chupak
IPC分类号: A61K31/4355 , A61K31/506 , A61P31/04 , C07D491/048
CPC分类号: C07D471/04 , C07D209/42 , C07D333/68 , C07D491/048
摘要: The disclosure provides compounds of formula I, II, III, IV, and V, including their salts, as well as compositions and methods of using the compounds. The compounds have activity against hepatitis C virus (HCV) and may be useful in treating those infected with HCV.
摘要翻译: 本公开提供式I,II,III,IV和V的化合物,包括它们的盐,以及使用该化合物的组合物和方法。 该化合物具有抗丙型肝炎病毒(HCV)的活性,可用于治疗HCV感染者。
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公开(公告)号:US08293909B2
公开(公告)日:2012-10-23
申请号:US12720182
申请日:2010-03-09
申请人: Richard Pracitto , John F. Kadow , John A. Bender , Brett R. Beno , Katharine A. Grant-Young , Ying Han , Piyasena Hewawasam , Andrew Nickel , Kyle E. Parcella , Kap-Sun Yeung , Louis S. Chupak
发明人: Richard Pracitto , John F. Kadow , John A. Bender , Brett R. Beno , Katharine A. Grant-Young , Ying Han , Piyasena Hewawasam , Andrew Nickel , Kyle E. Parcella , Kap-Sun Yeung , Louis S. Chupak
IPC分类号: C07D471/04 , A61K31/437
CPC分类号: C07D209/42 , C07D333/68 , C07D471/04 , C07D491/048
摘要: The disclosure provides compounds of formula I, II, III, IV, and V, including their salts, as well as compositions and methods of using the compounds. The compounds have activity against hepatitis C virus (HCV) and may be useful in treating those infected with HCV.
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公开(公告)号:US20120046294A1
公开(公告)日:2012-02-23
申请号:US13031777
申请日:2011-02-22
申请人: John F. Kadow , Richard Pracitto
发明人: John F. Kadow , Richard Pracitto
IPC分类号: A61K31/5025 , A61P31/12 , C07D487/04
CPC分类号: C07D487/04
摘要: The disclosure provides compounds of formula I, including their salts, as well as compositions and methods of using the compounds. The compounds have activity against hepatitis C virus (HCV) and may be useful in treating those infected with HCV.
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公开(公告)号:US08536338B2
公开(公告)日:2013-09-17
申请号:US13470727
申请日:2012-05-14
申请人: Richard Pracitto , John F. Kadow , John A. Bender , Brett R. Beno , Katharine A. Grant-Young , Ying Han , Piyasena Hewawasam , Andrew Nickel , Kyle E. Parcella , Kap-Sun Yeung , Louis S. Chupak
发明人: Richard Pracitto , John F. Kadow , John A. Bender , Brett R. Beno , Katharine A. Grant-Young , Ying Han , Piyasena Hewawasam , Andrew Nickel , Kyle E. Parcella , Kap-Sun Yeung , Louis S. Chupak
IPC分类号: A61K31/4355 , C07D491/044
CPC分类号: C07D471/04 , C07D209/42 , C07D333/68 , C07D491/048
摘要: The disclosure provides compounds of formula I, II, III, IV, and V, including their salts, as well as compositions and methods of using the compounds. The compounds have activity against hepatitis C virus (HCV) and may be useful in treating those infected with HCV.
摘要翻译: 本公开提供式I,II,III,IV和V的化合物,包括它们的盐,以及使用该化合物的组合物和方法。 该化合物具有抗丙型肝炎病毒(HCV)的活性,可用于治疗HCV感染者。
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公开(公告)号:US09546160B2
公开(公告)日:2017-01-17
申请号:US13465298
申请日:2012-05-07
申请人: Qi Chen , Omar D. Lopez , John A. Bender , Gan Wang , Van N. Nguyen , John F. Kadow , Nicholas A. Meanwell , Makonen Belema
发明人: Qi Chen , Omar D. Lopez , John A. Bender , Gan Wang , Van N. Nguyen , John F. Kadow , Nicholas A. Meanwell , Makonen Belema
IPC分类号: A01N43/50 , A61K31/415 , C07D403/14 , C07D405/14 , C07D413/14 , A61K31/4178 , A61K31/4184 , A61K31/5377 , A61K45/06
CPC分类号: C07D403/14 , A61K31/4178 , A61K31/4184 , A61K31/5377 , A61K45/06 , C07D405/14 , C07D413/14
摘要: The present disclosure relates to compounds, compositions and methods for the treatment of Hepatitis C virus (HCV) infection. Also disclosed are pharmaceutical compositions containing such compounds and methods for using these compounds in the treatment of HCV infection.
摘要翻译: 本公开涉及用于治疗丙型肝炎病毒(HCV)感染的化合物,组合物和方法。 还公开了含有这些化合物的药物组合物和使用这些化合物治疗HCV感染的方法。
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公开(公告)号:US08552047B2
公开(公告)日:2013-10-08
申请号:US13361541
申请日:2012-01-30
申请人: John A. Bender , Omar D. Lopez , Gan Wang , Makonen Belema , John F. Kadow
发明人: John A. Bender , Omar D. Lopez , Gan Wang , Makonen Belema , John F. Kadow
IPC分类号: A01N43/50 , A61K31/415 , C07D403/02
CPC分类号: C07D309/06 , A61K31/4178 , A61K45/06 , C07D405/14 , A61K2300/00
摘要: The present disclosure relates to compounds, compositions and methods for the treatment of hepatitis C virus (HCV) infection. Also disclosed are pharmaceutical compositions containing such compounds and methods for using these compounds in the treatment of HCV infection.
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