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公开(公告)号：US11953651B2
公开(公告)日：2024-04-09
申请号：US17410139
申请日：2021-08-24
发明人： Kevin P. McCabe , Robert B. Steffen , Hélène Aguilar , W. Anthony Martin , Susan W. Neadle , Ann-Marie Wong Meyers , Douglas G. Vanderlaan , Dominic P. Gourd , Kristy L. Canavan , Gregory A. Hill
IPC分类号： G02B1/04 , A61L12/04 , A61L12/08 , A61L27/34 , A61L27/50 , A61L27/54 , B29D11/00 , G02C7/04 , G02C13/00
CPC分类号： G02B1/043 , A61L12/04 , A61L12/08 , A61L27/34 , A61L27/50 , A61L27/54 , B29D11/00067 , G02C7/049 , G02C13/00 , A61L2300/452 , B29K2039/06
摘要： This invention relates to comfortable ophthalmic devices and methods of producing such devices.
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公开(公告)号：US11360241B2
公开(公告)日：2022-06-14
申请号：US17160847
申请日：2021-01-28
发明人： Kevin P. McCabe , Frank F. Molock, Jr. , Gregory A. Hill , Azaam Alli , Robert B. Steffen , Douglas G. Vanderlaan , James D. Ford
IPC分类号： G02B1/04 , A61L27/18 , A61L27/26 , A61L27/52 , C08F251/00 , C08F265/04 , C08F271/00 , C08F283/06 , C08F290/06 , C08F291/00 , G02C7/02 , C08F271/02 , C08F283/12
摘要： This invention includes a wettable biomedical device containing a high molecular weight hydrophilic polymer and a hydroxyl-functionalized silicone-containing monomer.
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公开(公告)号：US20210263340A1
公开(公告)日：2021-08-26
申请号：US17318093
申请日：2021-05-12
摘要： Provided are articles such as medical devices which comprise at least one water soluble, crosslinked copolymer. The primary polymer chains of the copolymer are hydrophilic and independently have a degree of polymerization in the range of about 10 to about 10,000. The water soluble, crosslinked copolymers of the present invention are free from terminal substrate associating segments. The copolymers may be incorporated into a formulation from which the article is made or may be contacted with the article post-formation.
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公开(公告)号：US11029539B2
公开(公告)日：2021-06-08
申请号：US16657163
申请日：2019-10-18
摘要： Provided are articles such as medical devices which comprise at least one water soluble, crosslinked copolymer. The primary polymer chains of the copolymer are hydrophilic and independently have a degree of polymerization in the range of about 10 to about 10,000. The water soluble, crosslinked copolymers of the present invention are free from terminal substrate associating segments. The copolymers may be incorporated into a formulation from which the article is made or may be contacted with the article post-formation.
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公开(公告)号：US10935696B2
公开(公告)日：2021-03-02
申请号：US16839156
申请日：2020-04-03
发明人： Kevin P. McCabe , Frank F. Molock, Jr. , Gregory A. Hill , Azaam Alli , Robert B. Steffen , Douglas G. Vanderlaan , James D. Ford
IPC分类号： G02B1/04 , A61L27/18 , A61L27/26 , A61L27/52 , C08F251/00 , C08F265/04 , C08F271/00 , C08F271/02 , C08F283/06 , C08F290/06 , C08F291/00 , C08F283/12 , G02C7/02
摘要： This invention includes a wettable biomedical device containing a high molecular weight hydrophilic polymer and a hydroxyl-functionalized silicone-containing monomer.
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公开(公告)号：US20180203161A1
公开(公告)日：2018-07-19
申请号：US15917924
申请日：2018-03-12
发明人： Kevin P. McCabe , Frank F. Molock, JR. , Gregory A. Hill , Azaam Alli , Robert B. Steffen , Douglas G. Vanderlaan , James D. Ford
IPC分类号： G02B1/04 , A61L27/26 , G02C7/02 , C08F291/00 , A61L27/18 , A61L27/52 , C08F251/00 , C08F265/04 , C08F271/00 , C08F271/02 , C08F283/06 , C08F283/12 , C08F290/06 , C08L83/04
CPC分类号： G02B1/043 , A61L27/18 , A61L27/26 , A61L27/52 , C08F251/00 , C08F265/04 , C08F271/00 , C08F271/02 , C08F283/06 , C08F283/12 , C08F290/06 , C08F291/00 , G02C7/022 , C08L83/04
摘要： This invention includes a wettable biomedical device containing a high molecular weight hydrophilic polymer and a hydroxyl-functionalized silicone-containing monomer.
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公开(公告)号：US20170299894A1
公开(公告)日：2017-10-19
申请号：US15638557
申请日：2017-06-30
摘要： Provided are articles such as medical devices which comprise at least one water soluble, crosslinked copolymer. The primary polymer chains of the copolymer are hydrophilic and independently have a degree of polymerization in the range of about 10 to about 10,000. The water soluble, crosslinked copolymers of the present invention are free from terminal substrate associating segments. The copolymers may be incorporated into a formulation from which the article is made or may be contacted with the article post-formation.
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8.发明申请公开(公告)号：US20130317131A1
公开(公告)日：2013-11-28
申请号：US13840919
申请日：2013-03-15
IPC分类号： G02B1/04
CPC分类号： G02B1/043 , B82Y30/00 , C08F293/005 , C08J7/00 , C08L53/00 , C08L101/14 , C08L83/04 , C08L81/00
摘要： Provided are compositions comprising a block copolymer of the following formula: [A]-B-[Q], wherein [A] is a polymer that has an affinity for a substrate; B is a linking group comprising an optionally-substituted, polyvalent linking group having a molecular weight of no more than 1000 g/mole; and [Q] comprises a semi-crosslinked, ungelled polymer derived from copolymerization of an ethylenically unsaturated monomer with a poly-functional ethylenically unsaturated monomer. Such block copolymers are cross-linked via the [Q] segment, but not macroscopically gelled. The [Q] segment is hydrophilic and has a degree of polymerization in the range of about 10 to about 10,000. The [A] segment is located on at least one terminal end of said block copolymer, comprises between about 1 and about 200 repeating units. The block copolymer is associated, via the linear substrate associative segment with a surface comprising at least one hydrophobic site, such as a silicone hydrogel. The polymers may be incorporated into a formulation from which the silicone hydrogel is made or may be contacted with the silicone hydrogel post-formation.
摘要翻译： 提供了包含下式的嵌段共聚物的组合物：[A] -B- [Q]，其中[A]是对底物具有亲和性的聚合物; B是包含分子量不超过1000g / mol的任选取代的多价连接基团的连接基团; 和[Q]包含衍生自烯属不饱和单体与多官能烯键式不饱和单体共聚的半交联的未凝胶聚合物。 这种嵌段共聚物通过[Q]链段交联，但不是宏观胶凝的。 [Q]链段是亲水性的并且聚合度在约10至约10,000的范围内。 [A]链段位于所述嵌段共聚物的至少一个末端，包含约1至约200个重复单元。 嵌段共聚物通过线性底物缔合链段与包含至少一个疏水位点的表面如硅氧烷水凝胶缔合。 聚合物可以掺入制备硅氧烷水凝胶的制剂中，或者可与硅氧烷水凝胶后处理接触。
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公开(公告)号：US20240142666A1
公开(公告)日：2024-05-02
申请号：US18489093
申请日：2023-10-18
发明人： Kevin P. McCabe , Robert B. Steffen , Hélène Aguilar , W. Anthony Martin , Susan W. Neadle , Ann-Marie Wong Meyers , Douglas G. Vanderlaan , Dominic P. Gourd , Kristy L. Canavan , Gregory A. Hill
IPC分类号： G02B1/04 , A61L12/04 , A61L12/08 , A61L27/34 , A61L27/50 , A61L27/54 , B29D11/00 , G02C7/04 , G02C13/00
CPC分类号： G02B1/043 , A61L12/04 , A61L12/08 , A61L27/34 , A61L27/50 , A61L27/54 , B29D11/00067 , G02C7/049 , G02C13/00 , A61L2300/452 , B29K2039/06
摘要： This invention relates to comfortable ophthalmic devices and methods of producing such devices.
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公开(公告)号：US11782296B2
公开(公告)日：2023-10-10
申请号：US17318093
申请日：2021-05-12
CPC分类号： G02C7/049 , G02B1/043 , G02C2202/16 , G02B1/043 , C08L81/00 , G02B1/043 , C08L83/04 , G02B1/043 , C08L101/14
摘要： Provided are articles such as medical devices which comprise at least one water soluble, crosslinked copolymer. The primary polymer chains of the copolymer are hydrophilic and independently have a degree of polymerization in the range of about 10 to about 10,000. The water soluble, crosslinked copolymers of the present invention are free from terminal substrate associating segments. The copolymers may be incorporated into a formulation from which the article is made or may be contacted with the article post-formation.
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