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公开(公告)号:US20090227571A1
公开(公告)日:2009-09-10
申请号:US11921366
申请日:2006-06-30
申请人: Jon C. Loren , Todd Miller , Bijan Pedram , Charlene V. Rowley , Yixing Shen , Cornelis Arjan Van Oeveren , Lin Zhi
发明人: Jon C. Loren , Todd Miller , Bijan Pedram , Charlene V. Rowley , Yixing Shen , Cornelis Arjan Van Oeveren , Lin Zhi
IPC分类号: A61K31/54 , C12N5/02 , C12Q1/02 , C07C237/00 , A61K31/16 , C07D209/04 , A61K31/405 , C07C303/00 , A61K31/18 , A61K31/445 , C07D211/00 , C07D215/00 , A61K31/47 , A61K31/4427 , C07D471/00 , C07D401/14 , A61K31/497 , C07D413/00 , C07D417/00 , A61K31/5377
CPC分类号: C07C229/18 , C07C237/02 , C07C237/06 , C07C275/42 , C07C311/16 , C07C317/32 , C07C2601/14 , C07D209/16 , C07D215/38 , C07D295/185 , C07D295/26 , C07D401/04 , C07D471/04
摘要: Provided herein are compounds that bind to androgen receptors and modulate the activity and/or the amount of androgen receptors and to methods for making and using such compounds. Also provided are compositions including such compounds and methods for making and using such compositions.
摘要翻译: 本文提供了结合雄激素受体并调节雄激素受体的活性和/或量的化合物以及制备和使用这些化合物的方法。 还提供了包含这些化合物的组合物和用于制备和使用这些组合物的方法。
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公开(公告)号:US20060116417A1
公开(公告)日:2006-06-01
申请号:US11256572
申请日:2005-10-21
申请人: Jyun-Hung Chen , E. Kallel , Thomas Lau , Matthew McNeill , Todd Miller , Bao Nguyen , Richard Penuliar , Dean Phillips , Daniel Ruppar , Lin Zhi , Jackline Dalgard
发明人: Jyun-Hung Chen , E. Kallel , Thomas Lau , Matthew McNeill , Todd Miller , Bao Nguyen , Richard Penuliar , Dean Phillips , Daniel Ruppar , Lin Zhi , Jackline Dalgard
IPC分类号: A61K31/404 , C07D209/36
CPC分类号: C07D471/04 , C07D209/40 , C07D217/24 , C07D239/04 , C07D239/60 , C07D277/04 , C07D277/54 , C07D401/04 , C07D403/12 , C07D405/04 , C07D409/04 , C07D417/12
摘要: Disclosed herein are compounds of Formula (I), (II), and (III) pharmaceutical compositions comprising the same, methods of modulating the activity a thrombopoietin receptor using the same, methods of identifying compounds as thrombopoietin receptor modulators, and methods of treating disease by administering a compound of the invention to a patient in need thereof.
摘要翻译: 本文公开了式(I),(II)和(III)的化合物,其包含其的药物组合物,使用其调节血小板生成素受体的活性的方法,鉴定化合物作为血小板生成素受体调节剂的方法,以及治疗疾病的方法 通过向有需要的患者施用本发明的化合物。
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公开(公告)号:US20080103190A1
公开(公告)日:2008-05-01
申请号:US11963115
申请日:2007-12-21
申请人: Jyun-Hung Chen , E. Kallel , Thomas Lau , Matthew McNeill , Todd Miller , Bao Nguyen , Richard Penuliar , Dean Phillips , Daniel Ruppar , Lin Zhi , Jackline Dalgard
发明人: Jyun-Hung Chen , E. Kallel , Thomas Lau , Matthew McNeill , Todd Miller , Bao Nguyen , Richard Penuliar , Dean Phillips , Daniel Ruppar , Lin Zhi , Jackline Dalgard
IPC分类号: A61K31/404 , A61P7/00 , C07D209/30 , C12N5/00 , G01N33/53
CPC分类号: C07D471/04 , C07D209/40 , C07D217/24 , C07D239/04 , C07D239/60 , C07D277/04 , C07D277/54 , C07D401/04 , C07D403/12 , C07D405/04 , C07D409/04 , C07D417/12
摘要: Disclosed herein are compounds, pharmaceutical compositions comprising the same, methods of modulating the activity a thrombopoietin receptor using the same, methods of identifying compounds as thrombopoietin receptor modulators, and methods of treating disease by administering a compound of the invention to a patient in need thereof.
摘要翻译: 本文公开了化合物,包含其的药物组合物,使用其调节血小板生成素受体的活性的方法,鉴定化合物作为血小板生成素受体调节剂的方法,以及通过向有需要的患者施用本发明化合物来治疗疾病的方法 。
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公开(公告)号:US08678466B2
公开(公告)日:2014-03-25
申请号:US13435153
申请日:2012-03-30
申请人: Nicholas Earl Merkel , Todd Miller
发明人: Nicholas Earl Merkel , Todd Miller
CPC分类号: B60K37/00 , B60K2350/94 , B60K2350/943
摘要: An instrument panel assembly and method of installing an instrument panel assembly is provided. The instrument panel assembly includes a base having a side portion. The side portion includes a first mounting aperture. A side panel is dimensioned to cover the side portion. The side panel is configured to be angled relative to the side portion so as to preventing other tabs from scratching the exterior surface of the instrument panel assembly.
摘要翻译: 提供了仪表板组件和安装仪表板组件的方法。 仪表板组件包括具有侧部的底座。 侧部包括第一安装孔。 侧板的尺寸设计成覆盖侧部。 侧板被构造成相对于侧部成一定角度,以防止其它翼片刮擦仪表板组件的外表面。
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公开(公告)号:US20130257086A1
公开(公告)日:2013-10-03
申请号:US13435153
申请日:2012-03-30
申请人: Nicholas Earl Merkel , Todd Miller
发明人: Nicholas Earl Merkel , Todd Miller
CPC分类号: B60K37/00 , B60K2350/94 , B60K2350/943
摘要: An instrument panel assembly and method of installing an instrument panel assembly is provided. The instrument panel assembly includes a base having a side portion. The side portion includes a first mounting aperture. A side panel is dimensioned to cover the side portion. The side panel is configured to be angled relative to the side portion so as to preventing other tabs from scratching the exterior surface of the instrument panel assembly.
摘要翻译: 提供了仪表板组件和安装仪表板组件的方法。 仪表板组件包括具有侧部的底座。 侧部包括第一安装孔。 侧板的尺寸设计成覆盖侧部。 侧板被构造成相对于侧部成一定角度,以防止其它翼片刮擦仪表板组件的外表面。
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公开(公告)号:US20060068346A1
公开(公告)日:2006-03-30
申请号:US11112781
申请日:2005-04-22
申请人: John Nowakowski , J.J. Lukacs , Todd Miller , Thomas Robertson
发明人: John Nowakowski , J.J. Lukacs , Todd Miller , Thomas Robertson
IPC分类号: F23C5/00
CPC分类号: F23D14/24 , F23C6/045 , F23C2900/06041
摘要: Hot products of combustion are provided beside an outer surface of a load to be heated, and are given a non-uniform temperature profile in a control direction extending across the outer surface of the load. The non-uniform temperature profile of the hot products of combustion is varied within a range that is predetermined relative to the distance that the outer surface of the load extends in the control direction, whereby the load can be given a predetermined temperature profile in the control direction.
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公开(公告)号:USD471015S1
公开(公告)日:2003-03-04
申请号:US29123193
申请日:2000-05-12
申请人: Sun Lacy , Leane M. Lefever , Tony Bible , Jerry Williamson , Todd Miller , Harold Angles , Vicki Lahna , Rob House
设计人: Sun Lacy , Leane M. Lefever , Tony Bible , Jerry Williamson , Todd Miller , Harold Angles , Vicki Lahna , Rob House
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公开(公告)号:USD436444S1
公开(公告)日:2001-01-23
申请号:US29111918
申请日:1999-10-06
申请人: Sun Lacy , Leane M. Lefever , Chris Corp , Todd Miller , Vicki Lahna
设计人: Sun Lacy , Leane M. Lefever , Chris Corp , Todd Miller , Vicki Lahna
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公开(公告)号:US06167930A
公开(公告)日:2001-01-02
申请号:US09365367
申请日:1999-07-30
申请人: Tom Harper , Duane Bice , Jack Hindel , Tim Teal , Leane Lefever , Vicki Lahna , Todd Miller , Chris Corp
发明人: Tom Harper , Duane Bice , Jack Hindel , Tim Teal , Leane Lefever , Vicki Lahna , Todd Miller , Chris Corp
IPC分类号: B27J100
CPC分类号: B27J1/02
摘要: Each of two end sections and one middle section of the present basket form is formed with a centrally and axially disposed passageway and with a pair of diametrically opposing passageways spaced radially outwardly from the central passageway. All of the passageways in one of the sections are simultaneously alignable with corresponding passageways in the other sections. The central passageways are adapted to receive a mounting member. Each of the radially outwardly disposed passageways are adapted to receive a bolt, and a wing nut is tightened onto an outwardly projecting threaded end of each bolt to hold the separable sections of the form in alignment with one another. The middle section of the form may be removed and the two end sections held in alignment with one another to accommodate a shallower basket.
摘要翻译: 当前的篮子形式的两个端部部分和一个中间部分中的每一个形成有中心且轴向设置的通道,并且具有与中心通道径向向外间隔开的一对直径相对的通道。 其中一个部分的所有通道与其他部分的相应通道同时对准。 中央通道适于接收安装构件。 径向向外设置的通道中的每一个适于接收螺栓,并且翼形螺母被紧固到每个螺栓的向外突出的螺纹端上,以将形式的可分离部分保持彼此对齐。 形式的中间部分可以被移除,并且两个端部彼此保持一致以容纳较浅的筐。
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公开(公告)号:US08473611B1
公开(公告)日:2013-06-25
申请号:US12554663
申请日:2009-09-04
申请人: Richard E. Meier , Roger G. Harrison , Todd Miller
发明人: Richard E. Meier , Roger G. Harrison , Todd Miller
IPC分类号: G06F15/173
CPC分类号: G06F17/30902
摘要: A request for content is received at a content filter of a computer system, and a determination is made, based on a referrer included in the request, regarding a root site directly or indirectly associated with the request. Thereafter, the content is permitted or not permitted according to whether or not the root site is a permitted site and a site associated with the content is categorized in a semantically equivalent content category with the root site. The determination regarding the root site may involve consulting a referrer chain cache storing lists of referrers which associate referring Web sites with root sites from which referrals originate.
摘要翻译: 在计算机系统的内容过滤器处接收对内容的请求,并且基于包括在请求中的引用者,确定与请求直接或间接相关联的根站点。 此后,根据站点是否是允许站点,允许还是不允许内容,并且与内容相关联的站点被分类为具有根站点的语义上等同的内容类别。 关于根站点的确定可能涉及咨询引用者链缓存,其存储将引用网站与引用来源的根站点相关联的引用者的列表。
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