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公开(公告)号：US06426331B1
公开(公告)日：2002-07-30
申请号：US09349208
申请日：1999-07-07
申请人： Judi McKinney , Brian C. Raimundo , Timothy D. Cushing , Hiromitsu Yoshimura , Yutaka Ohuchi , Akira Hiratate , Hiroshi Fukushima
发明人： Judi McKinney , Brian C. Raimundo , Timothy D. Cushing , Hiromitsu Yoshimura , Yutaka Ohuchi , Akira Hiratate , Hiroshi Fukushima
IPC分类号： C07K506
CPC分类号： C07K5/06034 , A61K38/00 , C07K5/06191
摘要： Compounds, compositions and methods that are useful in the treatment of immunoregulatory conditions and disorders are provided herein. In particular, the invention provides compounds which modulate the function of a Signal Transducer and Activator of Transcription (STAT) protein. The compounds are represented by the general formula: wherein Y, Ar, X, A2, A1, R1 and R2 are defined herein. The compounds are useful to treat, for example, allergic and inflammatory conditions and disorders.
摘要翻译： 本文提供了可用于治疗免疫调节病症和病症的化合物，组合物和方法。 特别地，本发明提供调节信号转导和转录激活因子（STAT）蛋白的功能的化合物。 化合物由通式表示：其中Y，Ar，X，A2，A1，R1和R2如本文所定义。 该化合物可用于治疗例如过敏性和炎症性疾病和病症。
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公开(公告)号：US07304166B2
公开(公告)日：2007-12-04
申请号：US10525748
申请日：2003-08-27
IPC分类号： C07D207/10
CPC分类号： A61K31/40 , C07D207/16
摘要： A benzenesulfonate salt of (2S,4S)-2-cyano-4-fluoro-1-[(2-hydroxy-1,1-dimethyl)ethylamino]acetylpyrrolidine that has an excellent DPPIV inhibition activity as well as physical properties (e.g., stability) required for pharmaceutical preparations. The present invention allows easy obtaining of the compound in high-purity uniform crystal form with excellent solid-state stability.
摘要翻译： 具有优异的DPPIV抑制活性以及物理性质的（2S，4S）-2-氰基-4-氟-1 - [（2-羟基-1,1-二甲基）乙基氨基]乙酰基吡咯烷的苯磺酸盐， 稳定性）。 本发明可以容易地获得具有优异的固态稳定性的高纯度均匀晶体形式的化合物。
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公开(公告)号：US20060106087A1
公开(公告)日：2006-05-18
申请号：US10525748
申请日：2003-08-27
IPC分类号： A61K31/401 , C07D207/36
CPC分类号： A61K31/40 , C07D207/16
摘要： A benzenesulfonate salt of (2S,4S)-2-cyano-4-fluoro-1-[(2-hydroxy-1,1-dimethyl)ethylamino]acetylpyrrolidine that has an excellent DPPIV inhibition activity as well as physical properties (e.g., stability) required for pharmaceutical preparations. The present invention allows easy obtaining of the compound in high-purity uniform crystal form with excellent solid-state stability.
摘要翻译： 具有优异的DPPIV抑制活性以及物理性质的（2S，4S）-2-氰基-4-氟-1 - [（2-羟基-1,1-二甲基）乙基氨基]乙酰基吡咯烷的苯磺酸盐， 稳定性）。 本发明可以容易地获得具有优异的固态稳定性的高纯度均匀晶体形式的化合物。
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公开(公告)号：US20070112205A1
公开(公告)日：2007-05-17
申请号：US11556064
申请日：2006-11-02
IPC分类号： C07D207/24
CPC分类号： C07D401/06 , C07D207/16 , Y02P20/55
摘要： A compound represented by the following formula or a salt thereof: wherein A is a hydrogen atom or a fluorine atom, R1 is —CONH2 or —CN and R2 is a hydrogen atom, a tert-butoxycarbonyl group, a trityl group, an o-nitrobenzenesulfenyl group, a benzyloxycarbonyl group, a fluorenyloxycarbonyl group, an allyloxycarbonyl group or —C(═O)—CH2-Rc wherein Rc is a halogen atom, a methanesulfonyloxy group, a p-toluenesulfonyloxy group or a hydroxyl group.
摘要翻译： 由下式表示的化合物或其盐：其中A是氢原子或氟原子，R 1是-CONH 2或-CN和R SUP > 2是氢原子，叔丁氧基羰基，三苯甲基，邻硝基苯硫基，苄氧羰基，芴氧基羰基，烯丙氧基羰基或-C（ - ） - 2 Rc其中R c是卤素原子，甲磺酰氧基，对甲苯磺酰氧基或羟基。
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公开(公告)号：US20070112059A1
公开(公告)日：2007-05-17
申请号：US11556096
申请日：2006-11-02
IPC分类号： A61K31/401 , C07D207/24
CPC分类号： C07D401/06 , C07D207/16 , Y02P20/55
摘要： Cyanopyrrolidine compound represented by Formula (1): Wherein the substituents are as defined herein. The compounds inhibit dipeptidyl peptidase IV.
摘要翻译： 由式（1）表示的吡咯并吡咯烷化合物：其中取代基如本文所定义。 该化合物抑制二肽基肽酶IV。
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公开(公告)号：US20130128163A1
公开(公告)日：2013-05-23
申请号：US13812937
申请日：2011-07-25
IPC分类号： G02F1/1343
CPC分类号： G02F1/13439 , G02B27/2214 , G02F1/133512 , G02F1/133784 , G02F1/134309 , G02F1/1347 , G02F2201/124
摘要： Provided is a switching liquid crystal panel and a display device that have novel structures that are capable of preventing luminous regions from appearing in the light transmitting parts, in the vicinities of boundaries thereof with the light shielding parts. The switching liquid crystal panel includes a pair of substrates (26a, 26b) having a twisted nematic type liquid crystal layer (24) interposed therebetween, and a plurality of light shield forming electrodes (30) that are formed on at least one of the pair of the substrates (26a, 26b) and that form light shielding parts (40) of a parallax barrier (16) in cooperation with a counter electrode (34) when a voltage is applied, the counter electrode (34) being is opposed to the light shield forming electrodes (30) with the liquid crystal layer (24) interposed therebetween. A rubbing direction for an alignment film (36a) provided on the substrate (26a) side on which the light shield forming electrodes (30) are formed is at an angle of 45° or less to a lengthwise direction of the light shield forming electrodes (30).
摘要翻译： 提供一种开关液晶面板和显示装置，其具有能够防止发光部在其与遮光部的边界附近在透光部中出现的新颖结构。 开关液晶面板包括夹在其间的扭曲向列型液晶层（24）的一对基板（26a，26b）和形成在该对中的至少一个上的多个遮光膜形成电极（30） 的基板（26a，26b），并且当施加电压时与对电极（34）配合形成视差屏障（16）的遮光部分（40），所述对置电极（34）与 具有液晶层（24）的遮光板形成电极（30）。 设置在其上形成有遮光膜形成电极（30）的基板（26a）侧的取向膜（36a）的摩擦方向与遮光板形成电极的长度方向成45°以下 30）。
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公开(公告)号：US08149358B2
公开(公告)日：2012-04-03
申请号：US12446663
申请日：2007-10-12
申请人： Tomoo Takatani , Akira Imai , Hiroshi Fukushima , Koji Yabuta
发明人： Tomoo Takatani , Akira Imai , Hiroshi Fukushima , Koji Yabuta
IPC分类号： G02F1/1333
CPC分类号： G02F1/133509 , G02F2001/133562 , G07F19/20 , G07F19/205
摘要： An ATM of the present invention includes a liquid crystal display panel having, between two transparent substrates, (i) an image forming layer including at least a liquid crystal layer and a pixel section in which RGB pixels are arranged in a matrix manner, and (ii) a plurality of barriers (16) for splitting a display image formed by the image forming layer into a plurality of images each having a specific viewing angle. The plurality of barriers are provided so as to face the image forming layer. The plurality of barriers (16) are extended in a horizontal direction (lateral direction) parallel to the surfaces of the transparent substrates, and provided at substantially regular intervals in a direction perpendicular to the horizontal direction, parallel to the surfaces of the transparent substrates (i.e., in a longitudinal direction). This makes it possible to provide an ATM that prevents a peep at private information such as a secret number without giving, whichever direction a display is viewed, a false recognition that the display is in a resting state.
摘要翻译： 本发明的ATM包括在两个透明基板之间具有至少包括液晶层的图像形成层和RGB像素以矩阵方式布置的像素部分的液晶显示面板，以及（ ii）用于将由图像形成层形成的显示图像分割成多个具有特定视角的图像的多个屏障（16）。 设置多个屏障以面对图像形成层。 多个屏障（16）在与透明基板的表面平行的水平方向（横向）上延伸，并且在与透明基板的表面平行的水平方向的垂直方向上以大致规则的间隔设置 即沿纵向）。 这使得可以提供一种ATM，其防止窥视诸如秘密号码的私人信息，而不给出视觉显示的哪个方向，显示处于静止状态的错误识别。
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公开(公告)号：US20120057229A1
公开(公告)日：2012-03-08
申请号：US13263175
申请日：2009-12-22
申请人： Ryo Kikuchi , Hiroshi Fukushima , Tomoo Takatani
发明人： Ryo Kikuchi , Hiroshi Fukushima , Tomoo Takatani
IPC分类号： G02B27/22
CPC分类号： G02B27/2214 , G02B5/201 , H04N13/305 , H04N13/31 , H04N13/312 , H04N13/356
摘要： Provided is a display apparatus that can operate both in a portrait mode and a landscape mode, and that exhibits high front brightness and excellent resolution in both planar image display (2D display) and stereoscopic image display (3D display). The display apparatus of the present invention is a display apparatus provided with a display panel including a plurality of pixel areas, a parallax barrier disposed on one side of the display panel, and a lenticular lens disposed on the other side of the display panel. The parallax barrier is provided with a light-blocking sections and a light-transmitting section along a row direction or a column direction of the pixel areas. The lenticular lens includes a plurality of cylindrical lenses arrayed in the row direction or the column direction of the pixel areas. The array direction of the light-blocking sections and the light-transmitting sections is perpendicular to the array direction of the cylindrical lenses.
摘要翻译： 提供了一种能够以纵向模式和横向模式同时操作并且在平面图像显示（2D显示）和立体图像显示（3D显示）两者中呈现高前亮度和优异分辨率的显示装置。 本发明的显示装置是设置有包括多个像素区域的显示面板，设置在显示面板一侧的视差屏障和设置在显示面板另一侧的双凸透镜的显示装置。 视差屏障设置有沿着像素区域的行方向或列方向的遮光部分和透光部分。 双凸透镜包括沿像素区域的行方向或列方向排列的多个柱面透镜。 遮光部和透光部的排列方向垂直于柱面透镜的排列方向。
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公开(公告)号：US07978167B2
公开(公告)日：2011-07-12
申请号：US11525033
申请日：2006-09-22
申请人： Koji Yabuta , Hiroshi Fukushima , Akira Imai , Tomoo Takatani
发明人： Koji Yabuta , Hiroshi Fukushima , Akira Imai , Tomoo Takatani
IPC分类号： G09G3/36
CPC分类号： G09G3/3611 , G02F1/1323 , G02F1/133753 , G02F1/13471 , G09G3/28 , G09G3/3208 , G09G2300/023 , G09G2320/068
摘要： A display section of a portable phone includes a first polarizer, a switching panel section, a reflective polarizer, and a main panel section. The switching panel section has a liquid crystal layer including a plurality of regions having at least two different alignment directions. This makes it possible, by utilizing the difference in the alignment direction of the liquid crystal layer, to make the image difficult to observe by a sight-line from an oblique direction. Furthermore, it is also possible, by utilizing the mirror-surface displaying caused by the reflective polarizer, to make the image significantly difficult to observe.
摘要翻译： 便携式电话的显示部分包括第一偏振器，开关面板部分，反射偏振器和主面板部分。 切换面板部分具有包括具有至少两个不同对准方向的多个区域的液晶层。 通过利用液晶层的取向方向的差异，可以使倾斜方向上的视线难以观察图像。 此外，通过利用由反射偏振器引起的镜面显示，也可以使图像显着难以观察。
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公开(公告)号：US07911112B2
公开(公告)日：2011-03-22
申请号：US11919994
申请日：2006-12-14
申请人： Yusuke Adachi , Hiroshi Fukushima
发明人： Yusuke Adachi , Hiroshi Fukushima
CPC分类号： H01L41/0913 , H02N2/004 , H02N2/0065 , H02N2/026 , H02N2/103
摘要： An ultrasonic actuator includes: a piezoelectric element 1 for generating a bending vibration and a stretching vibration; and a driver element 2 attached to a surface of the piezoelectric element 1 facing the direction of the bending vibration in point contact with the piezoelectric element 1 and actuated in accordance with the vibration of the piezoelectric element 1 to output driving force.
摘要翻译： 超声波致动器包括：用于产生弯曲振动和拉伸振动的压电元件1; 以及驱动元件2，其附接到压电元件1的面对与压电元件1接触的弯曲振动的方向并根据压电元件1的振动而被致动以输出驱动力的表面。
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