-
公开(公告)号:US20100029610A1
公开(公告)日:2010-02-04
申请号:US12492180
申请日:2009-06-26
申请人: Juswinder Singh , Russell Petter , Richland Wayne Tester , Arthur F. Kluge , Hormoz Mazdiyasni , William Frederick Westlin, III , Deqiang Niu , Lixin Qiao
发明人: Juswinder Singh , Russell Petter , Richland Wayne Tester , Arthur F. Kluge , Hormoz Mazdiyasni , William Frederick Westlin, III , Deqiang Niu , Lixin Qiao
IPC分类号: A61K31/397 , C07D239/02 , A61K31/505 , C12N9/99 , C12Q1/48 , C07D401/02 , C07D265/36 , A61K31/538 , C07D413/02 , A61K31/5377 , A61K31/496 , A61P37/00 , A61P35/00
CPC分类号: A61K31/505 , A61K31/506 , A61K31/5377 , C07D239/47 , C07D239/48 , C07D401/12 , C07D401/14 , C07D403/12 , C07D407/12 , C07D413/12 , C07D413/14 , C07D417/14 , C07D471/04 , C07D487/04 , C07D487/18
摘要: The present invention provides compounds, pharmaceutically acceptable compositions thereof, and methods of using the same.
摘要翻译: 本发明提供化合物,其药学上可接受的组合物及其使用方法。
-
公开(公告)号:US08338439B2
公开(公告)日:2012-12-25
申请号:US12648693
申请日:2009-12-29
申请人: Juswinder Singh , Russell Petter , Richland Wayne Tester , Arthur F. Kluge , Hormoz Mazdiyasni , William Frederick Westlin, III , Deqiang Niu , Lixin Qiao
发明人: Juswinder Singh , Russell Petter , Richland Wayne Tester , Arthur F. Kluge , Hormoz Mazdiyasni , William Frederick Westlin, III , Deqiang Niu , Lixin Qiao
IPC分类号: A61K31/505
CPC分类号: A61K31/505 , A61K31/506 , A61K31/519 , A61K31/5377 , A61K31/538 , A61K31/541 , A61K45/06 , C07D239/47 , C07D239/48 , C07D401/12 , C07D401/14 , C07D403/12 , C07D405/12 , C07D405/14 , C07D407/12 , C07D413/12 , C07D413/14 , C07D471/04 , C07D487/04 , C07D487/08 , C07D487/18 , C07D495/04
摘要: The present invention provides 2,4-disubstituted pyrimidine compounds useful as kinase inhibitors, pharmaceutically acceptable compositions thereof, and methods of using the same. In some embodiments, the present invention provides a compound of formula I-a or I-b: wherein each of Ring A, Ring B, W1, W2, Ry, Rv, Rx, m, p, and R1 is described herein.
摘要翻译: 本发明提供可用作激酶抑制剂的2,4-二取代嘧啶化合物,其药学上可接受的组合物及其使用方法。 在一些实施方案中,本发明提供式I-a或I-b的化合物:其中环A,环B,W1,W2,Ry,Rv,Rx,m,p和R1各自在本文中进行描述。
-
公开(公告)号:US08450335B2
公开(公告)日:2013-05-28
申请号:US12492180
申请日:2009-06-26
申请人: Juswinder Singh , Russell Petter , Richland Wayne Tester , Arthur F. Kluge , Hormoz Mazdiyasni , William Frederick Westlin, III , Deqiang Niu , Lixin Qiao
发明人: Juswinder Singh , Russell Petter , Richland Wayne Tester , Arthur F. Kluge , Hormoz Mazdiyasni , William Frederick Westlin, III , Deqiang Niu , Lixin Qiao
IPC分类号: A61K31/505
CPC分类号: A61K31/505 , A61K31/506 , A61K31/5377 , C07D239/47 , C07D239/48 , C07D401/12 , C07D401/14 , C07D403/12 , C07D407/12 , C07D413/12 , C07D413/14 , C07D417/14 , C07D471/04 , C07D487/04 , C07D487/18
摘要: The present invention provides 2,4-disubstituted pyrimidine compounds useful as kinase inhibitors, pharmaceutically acceptable compositions thereof, and methods of using the same. In some embodiments, the present invention provides a compound of formula I-b: wherein each of Ring A, Ring B, W1, W2, Ry, Rv, Rx, m, p, and R1 is described herein.
摘要翻译: 本发明提供可用作激酶抑制剂的2,4-二取代嘧啶化合物,其药学上可接受的组合物及其使用方法。 在一些实施方案中,本发明提供式I-b的化合物:其中环A,环B,W1,W2,Ry,Rv,Rx,m,p和R1各自在本文中进行描述。
-
公开(公告)号:US20100249092A1
公开(公告)日:2010-09-30
申请号:US12648693
申请日:2009-12-29
申请人: Juswinder Singh , Russell Petter , Richland Wayne Tester , Arthur F. Kluge , Hormoz Mazdiyasni , William Frederick Westlin, III , Deqiang Niu , Lixin Qiao
发明人: Juswinder Singh , Russell Petter , Richland Wayne Tester , Arthur F. Kluge , Hormoz Mazdiyasni , William Frederick Westlin, III , Deqiang Niu , Lixin Qiao
IPC分类号: A61K31/505 , C07D239/48 , C07D401/12 , A61K31/506 , C07D401/04 , C07D403/12 , C07D413/14 , A61K31/538 , C07D413/12 , C07D401/14 , A61K31/5377 , C07D417/14 , A61K31/541 , C07D405/14 , A61P3/10 , A61P37/06 , A61P29/00 , A61P35/00 , A61P17/00 , A61P1/00 , A61P11/00 , A61P19/00 , A61P7/02 , C12Q1/48 , G01N33/53
CPC分类号: A61K31/505 , A61K31/506 , A61K31/519 , A61K31/5377 , A61K31/538 , A61K31/541 , A61K45/06 , C07D239/47 , C07D239/48 , C07D401/12 , C07D401/14 , C07D403/12 , C07D405/12 , C07D405/14 , C07D407/12 , C07D413/12 , C07D413/14 , C07D471/04 , C07D487/04 , C07D487/08 , C07D487/18 , C07D495/04
摘要: The present invention provides compounds, pharmaceutically acceptable compositions thereof, and methods of using the same.
摘要翻译: 本发明提供化合物,其药学上可接受的组合物及其使用方法。
-
公开(公告)号:US08309685B2
公开(公告)日:2012-11-13
申请号:US12497103
申请日:2009-07-02
申请人: Russell C. Petter , Juswinder Singh , Arthur F. Kluge , Deqiang Niu , Lixin Qiao , Shomir Ghosh
发明人: Russell C. Petter , Juswinder Singh , Arthur F. Kluge , Deqiang Niu , Lixin Qiao , Shomir Ghosh
IPC分类号: C07K5/08
CPC分类号: A61K47/48246 , A61K38/00 , A61K38/005 , A61K38/06 , A61K38/12 , A61K47/64 , C07D401/12 , C07K5/0202 , C07K5/06165 , C07K5/0804 , C07K5/0806 , C07K5/0808 , C07K5/081 , C07K5/0812 , C07K5/0815 , C07K5/0821 , C12N9/506 , C12N9/96 , C12Y304/00
摘要: The present invention provides compounds, pharmaceutically acceptable compositions thereof, and methods of using the same.
摘要翻译: 本发明提供化合物,其药学上可接受的组合物及其使用方法。
-
公开(公告)号:US20100041591A1
公开(公告)日:2010-02-18
申请号:US12497122
申请日:2009-07-02
申请人: Deqiang Niu , Russell C. Petter , Juswinder Singh , Arthur F. Kluge , Lixin Qiao
发明人: Deqiang Niu , Russell C. Petter , Juswinder Singh , Arthur F. Kluge , Lixin Qiao
CPC分类号: C07K5/081 , A61K38/00 , C07K5/0202 , C07K5/06165 , C07K5/0804 , C07K5/0806 , C07K5/0808 , C07K5/0812 , C07K5/0815 , C07K5/0821 , C12N9/506 , C12N9/96 , C12N9/99
摘要: The present invention provides compounds, pharmaceutically acceptable compositions thereof, and methods of using the same.
摘要翻译: 本发明提供化合物,其药学上可接受的组合物及其使用方法。
-
公开(公告)号:US08741837B2
公开(公告)日:2014-06-03
申请号:US13620573
申请日:2012-09-14
申请人: Deqiang Niu , Russell C. Petter , Juswinder Singh , Arthur F. Kluge , Lixin Qiao
发明人: Deqiang Niu , Russell C. Petter , Juswinder Singh , Arthur F. Kluge , Lixin Qiao
CPC分类号: C07K5/081 , A61K38/00 , C07K5/0202 , C07K5/06165 , C07K5/0804 , C07K5/0806 , C07K5/0808 , C07K5/0812 , C07K5/0815 , C07K5/0821 , C12N9/506 , C12N9/96 , C12N9/99
摘要: The present invention provides compounds, pharmaceutically acceptable compositions thereof, and methods of using the same.
摘要翻译: 本发明提供化合物,其药学上可接受的组合物及其使用方法。
-
公开(公告)号:US08293705B2
公开(公告)日:2012-10-23
申请号:US12497122
申请日:2009-07-02
申请人: Deqiang Niu , Russell C. Petter , Juswinder Singh , Arthur F. Kluge , Lixin Qiao
发明人: Deqiang Niu , Russell C. Petter , Juswinder Singh , Arthur F. Kluge , Lixin Qiao
IPC分类号: A61K38/00
CPC分类号: C07K5/081 , A61K38/00 , C07K5/0202 , C07K5/06165 , C07K5/0804 , C07K5/0806 , C07K5/0808 , C07K5/0812 , C07K5/0815 , C07K5/0821 , C12N9/506 , C12N9/96 , C12N9/99
摘要: The present invention provides compounds, pharmaceutically acceptable compositions thereof, and methods of using the same.
-
公开(公告)号:US20100069294A1
公开(公告)日:2010-03-18
申请号:US12497103
申请日:2009-07-02
申请人: Russell C. Petter , Juswinder Singh , Arthur F. Kluge , Deqiang Niu , Lixin Qiao , Shomir Ghosh
发明人: Russell C. Petter , Juswinder Singh , Arthur F. Kluge , Deqiang Niu , Lixin Qiao , Shomir Ghosh
CPC分类号: A61K47/48246 , A61K38/00 , A61K38/005 , A61K38/06 , A61K38/12 , A61K47/64 , C07D401/12 , C07K5/0202 , C07K5/06165 , C07K5/0804 , C07K5/0806 , C07K5/0808 , C07K5/081 , C07K5/0812 , C07K5/0815 , C07K5/0821 , C12N9/506 , C12N9/96 , C12Y304/00
摘要: The present invention provides compounds, pharmaceutically acceptable compositions thereof, and methods of using the same.
-
公开(公告)号:US20090176858A1
公开(公告)日:2009-07-09
申请号:US12339770
申请日:2008-12-19
申请人: Deqiang Niu , Russell C. Petter , Juswinder Singh , Arthur F. Kluge , Lixin Qiao
发明人: Deqiang Niu , Russell C. Petter , Juswinder Singh , Arthur F. Kluge , Lixin Qiao
IPC分类号: A61K31/4035 , C07D403/12 , C07D498/16 , A61P31/12
CPC分类号: C07D487/16 , A61K31/4035 , A61K31/407 , A61K31/506 , A61K38/00 , A61K45/06 , C07D403/12 , C07D403/14 , C07D487/04 , C07K5/06165 , C07K5/0806 , C07K5/0812 , C07K5/0827
摘要: The present invention provides compounds, pharmaceutically acceptable compositions thereof, and methods of using the same.
摘要翻译: 本发明提供化合物,其药学上可接受的组合物及其使用方法。
-
-
-
-
-
-
-
-
-