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1.
公开(公告)号:US20240228730A1
公开(公告)日:2024-07-11
申请号:US18558892
申请日:2022-05-24
Applicant: Kimberly-Clark Worldwide, Inc.
Inventor: Stephen Quirk , David W. Koenig
CPC classification number: C08J11/105 , A61L11/00 , C12N9/18 , C08J2367/04
Abstract: Methods and systems for simultaneous degradation and decontamination of biopolymers such as polyhydroxyalkanoates are described. The enzymes encompass extremophilic enzymes that can be incorporated into a biodegradation process carried out at an environmental condition that is detrimental to a mesophilic pathogen. The materials, methods, and systems of the present disclosure are particularly directed to degrading and decontaminating used personal care products containing polyhydroxyalkanoate polymers using extremophilic and/or polyextremophilic depolymerase enzymes.
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2.
公开(公告)号:US20220010240A1
公开(公告)日:2022-01-13
申请号:US17482807
申请日:2021-09-23
Applicant: Kimberly-Clark Worldwide, Inc.
Inventor: Kathleen C. Engelbrecht , Stacy A. Mundschau , David W. Koenig , Scott W. Wenzel
IPC: C11D3/48 , C11D3/26 , C11D3/37 , A01N25/00 , C08L71/02 , C11D3/20 , A61K47/34 , A61K9/00 , A61K47/32 , A61K9/06 , A01N25/08 , A01N31/02 , A01N37/02 , A01N37/06 , A01N37/34 , A01N37/42 , A01N43/50 , A61K8/02 , A61K8/37 , A61K8/40 , A61K8/81 , A61K8/85 , A61K8/86 , A61K8/88 , A61K8/90 , A61Q17/00 , A61Q19/10 , C11D17/04
Abstract: Methods of inhibiting microbes from attaching to a surface and anti-adherent compositions are disclosed. One method can include providing an anti-adherent composition that includes an anti-adherent agent configured to inhibit microbes from attaching to the surface. The anti-adherent agent can be: Acrylates Copolymer, Trimethylpentanediol/Adipic Acid/Glycerin crosspolymer, Trimethylpentanediol/Adipic Acid Copolymer, Ethylhexyl Stearate, Ethylhexyl Salicylate, Acrylates/C12-22 Alkylmethacrylate Copolymer, Octocrylene, Ethylene Oxide/Propylene Oxide Block Copolymer, Polyquaternium-101, or any combinations thereof. The method can include applying the composition to the surface and allowing at least some of the composition to remain on the surface such that the anti-adherent agent inhibits microbes from attaching to the surface. The anti-adherent composition can include a humectant and can be non-antimicrobial.
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公开(公告)号:US20210308034A1
公开(公告)日:2021-10-07
申请号:US17056800
申请日:2019-05-22
Applicant: KIMBERLY-CLARK WORLDWIDE, INC.
Inventor: Elizabeth M. Doney , David W. Koenig , Jonathan Hofmekler
IPC: A61K8/73 , A61Q19/00 , A61K8/44 , A61K8/362 , A61K8/34 , A61K8/365 , A61K8/60 , A61K8/41 , A61L15/42 , A61L15/28 , A61L15/20
Abstract: A composition for providing or maintaining a healthy skin microbiota and methods of providing or maintaining a healthy skin microbiota are disclosed. The composition can be a prebiotic composition that can include a carrier and a skin microbiota balancing agent. In some aspects, the skin microbiota balancing agent can include at least one combination of carbohydrate sources including a first carbohydrate source and a second carbohydrate source. The skin microbiota balancing agent can be configured to provide at least two of the following desired ratios: a first desired ratio of Corynebaderium to Staphylococcus of 1.3, a second desired ratio of Corynebaderium to Micrococcus of 1.4, and a third desired ratio of Staphylococcus to Micrococcus of 1.1. The carbohydrate sources may be D-alanine, D-threonine, L-alanyl-glycine, succinic acid, α-keto-glutaric acid, m-tantaric acid, bromo succinic acid, mucic acid, phenylethyl-amine, inulin, oxalic acid, pectin, Tween 40 etc.
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公开(公告)号:US20210207067A1
公开(公告)日:2021-07-08
申请号:US16071343
申请日:2016-01-28
Applicant: KIMBERLY-CLARK WORLDWIDE, INC.
Inventor: Kathleen C. Engelbrecht , Stacy A. Mundschau , David W. Koenig , Scott W. Wenzel
Abstract: A composition for increasing the adherence of RNA viruses can include a liquid carrier, an adherent agent, and a humectant. The adherent agent can be water soluble or dispersible polyester, Methylcellulose, Polyvinylpyrrolidone, and combinations thereof. The composition can be non-antimicrobial. A method for removing RNA viruses from a surface can include providing a composition for increasing the adherence of RNA viruses, applying the composition to the surface, and removing at least some of the composition from the surface to remove RNA viruses from the surface.
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公开(公告)号:US20200345013A1
公开(公告)日:2020-11-05
申请号:US16935617
申请日:2020-07-22
Applicant: Kimberly-Clark Worldwide, Inc.
Inventor: David W. Koenig , Kathleen C. Engelbrecht , Amy L. Vanden Heuvel , Vinod Chaudhary , Scott W. Wenzel , Divesh Bhatt , Yang Huang , Aimin He
IPC: A01N65/00 , A01N31/16 , A01N43/32 , A01N45/00 , A01N65/08 , A01N65/20 , A01N65/30 , A01N65/40 , A61K36/708 , A61K8/02 , A61K36/48 , A61K36/8962 , A61K36/16 , A61K8/49 , A61K8/34 , A61K36/481 , A61K36/77 , A61Q17/00 , A61K36/482 , A61K8/9771 , A61K8/9789 , A61K8/9794 , A01N25/08 , A01N65/24
Abstract: A composition for inhibiting the attachment of microbes to an animate or inanimate surface is disclosed. The composition includes a carrier and an effective amount of an anti-adherent agent. The anti-adherent agents include botanical agents such as Soybean extract, Horse chestnut extract, Gypenoside, Resveratrol, Astragalus extract, Rhubarb root extract, Allium cepa extract, Cassia seed extract, Ginkgo biloba extract, and Silymarin, and combinations thereof. The efficacy of the botanical agents is microbe and surface dependent. Various delivery vehicles, including a wipe, may be used to deliver the composition to the surface.
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公开(公告)号:US20190300843A1
公开(公告)日:2019-10-03
申请号:US16346201
申请日:2017-10-25
Applicant: Kimberly-Clark Worldwide, Inc.
Inventor: Rebecca A. Vongsa , David W. Koenig
IPC: C12N1/20 , A61K35/741 , C12N1/04 , C12N1/36 , A23L33/135
Abstract: Methods for archiving and reconstituting a microbiome are disclosed. A method for archiving a microbiome can include collecting a sample including a microbial community defining the microbiome. The method can also include expanding the microbial community in the sample and preserving the sample to provide a preserved sample. Packaging the preserved sample to archive the microbiome can also form part of the method of archiving the microbiome.
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公开(公告)号:US10104894B2
公开(公告)日:2018-10-23
申请号:US15129668
申请日:2015-03-18
Applicant: Kimberly-Clark Worldwide, Inc.
Inventor: David W. Koenig , Douglas R. Hoffman , Cindy Korir-Morrison , Amy L. Vanden Heuvel
Abstract: A composition may be applied to animate and inanimate surfaces to render such surfaces antimicrobial for as long as the composition remains on the surface. The composition contains at least one pathogen-associated virus that is self-regenerating so that a user need not take steps to regenerate the material. The virus is or viruses are contained within a polymer matrix. The polymer matrix has the ability to maintain a desired moisture content to support the regeneration of the virus(es). Various methods of using the composition include the coating of animate and inanimate surfaces to prevent bacterial, viral, and fungal infections.
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8.
公开(公告)号:US09289520B2
公开(公告)日:2016-03-22
申请号:US14191617
申请日:2014-02-27
Applicant: Kimberly-Clark Worldwide, Inc.
Inventor: Jose K. Abraham , Paige Anunson , Kathleen C. Engelbrecht , David W. Koenig
CPC classification number: A61L2/03 , A61L2/04 , A61L2202/26
Abstract: A system for removing microorganisms from a surface is described. The system includes a conducting member, a voltage source, and an electrostatic field controller. The conducing member includes a nonwoven material incorporating conductive fibers. The controller is electrically connected to the conducting member and is configured to apply a DC voltage of about 15 volts or less to the conducting member via the voltage source. The surface to be contacted can include any surface present in households, food industry facilities, medical facilities, etc. Such surfaces can include tables, countertops, walls, cabinets, doors, door handles, door knobs, etc. The system can also be used to treat devices used in the aforementioned environments, such as food preparation equipment, medical devices, household appliances, etc. The system can reduce the amount of microorganisms on the surface by at least about 1 log (90%) without the use of chemicals, high voltages, or long exposure times.
Abstract translation: 描述了从表面除去微生物的系统。 该系统包括导电构件,电压源和静电场控制器。 引导构件包括结合导电纤维的非织造材料。 控制器电连接到导电构件,并且被配置为经由电压源向导电构件施加约15伏或更小的直流电压。 要接触的表面可以包括家庭中存在的任何表面,食品工业设施,医疗设施等。这些表面可以包括桌子,台面,墙壁,橱柜,门,门把手,门把手等。还可以使用该系统 用于治疗上述环境中使用的装置,例如食物制备设备,医疗器械,家用电器等。该系统可以在不使用化学物质的情况下将表面上的微生物量减少至少约1log(90%), 高电压或长曝光时间。
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公开(公告)号:US20140236610A1
公开(公告)日:2014-08-21
申请号:US14155688
申请日:2014-01-15
Applicant: Kimberly-Clark Worldwide, Inc.
Inventor: Michael A. Daley , David W. Koenig , Stephanie M. Martin , Kevin P. McGrath , Theodore T. Tower , Bruce S. Williamson , Clarice M. Theisen , Jennifer M. Kaminski , Christof J. Baer , Laura M. McLaughlin , Bryan John Semkuley
CPC classification number: G06Q50/22 , G06Q10/063 , G16H40/20
Abstract: There is provided a method for promoting hygiene and reducing illness in a resident care location. The method collects data from a resident care location by testing common areas and personal areas within the resident care location, uses data specific to each resident, uses this data to develop tasks for the caregiver(s), measures and scores compliance with the tasks, and provides feedback for improved compliance with the tasks.
Abstract translation: 提供了一种在居民护理位置促进卫生和减少疾病的方法。 该方法通过测试居民护理位置中的公共区域和个人区域来收集来自居民护理位置的数据,使用特定于每个居民的数据,使用该数据来开发护理人员的任务,措施和得分符合任务, 并提供反馈以改进对任务的遵从性。
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10.
公开(公告)号:US20240424036A1
公开(公告)日:2024-12-26
申请号:US18756711
申请日:2024-06-27
Applicant: Gregor Reid , Jeremy P. Burton , Behnam Abbasian , Kimberly-Clark Worldwide, Inc.
Inventor: Kathleen C. Engelbrecht , David W. Koenig , Elizabeth M. Doney , Gregor Reid , Jeremy Burton , Behnam Abbasian
IPC: A61K35/747 , A61K35/00
Abstract: Methods and compositions for preventing or treating incontinence, overactive bladder, or menstrual cramping in a subject are described. A method can include providing a composition. The composition can include a modification agent. The modification agent can include a strain of Lactobacillus or a ferment or a metabolite thereof. The modification agent can provide neuromodulation activity by up-regulating at least one of maoA enzymes, maoB enzymes, and grin-1 genes. The method can also include administering the composition to the subject to prevent or treat incontinence, overactive bladder, or menstrual cramping. In some aspects, the modification agent can decrease a level of extracellular ATP in a target environment.
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