-
公开(公告)号:US08969345B2
公开(公告)日:2015-03-03
申请号:US14236545
申请日:2012-08-03
IPC分类号: C07D413/14 , C07D471/04 , C07D487/04 , C07D495/04 , A61K31/4245 , A61K31/437 , A61K31/4439 , A61K31/454 , A61K31/4985 , A61K31/5025 , A61K31/519
CPC分类号: C07D495/04 , A61K31/335 , A61K31/4245 , A61K31/437 , A61K31/4439 , A61K31/454 , A61K31/4985 , A61K31/5025 , A61K31/519 , C07D413/14 , C07D471/04 , C07D487/04
摘要: A dibenzoxepin derivative represented by the following general formula (I) wherein Y is a hydrogen atom and the like, RA is a hydrogen atom and the like, X is the formula (b3) wherein RB is a hydrogen atom and the like, and the like, A is the formula (a18) wherein R1 is a hydrogen atom and the like, and RC and RD are the same or different and each is a hydrogen atom and the like, and the like, which has a PPARγ agonist activity and the like, and useful as a therapeutic agent and/or prophylaxis agent and the like for type 2 diabetes and the like, or a pharmaceutically acceptable salt thereof and the like is provided.
摘要翻译: 由以下通式(I)表示的二苯并氧杂环己烷衍生物,其中Y为氢原子等,RA为氢原子等,X为式(b3),其中RB为氢原子等, A是式(a18),其中R1是氢原子等,RC和RD相同或不同,各自是具有PPARγ激动剂活性的氢原子等,以及 作为2型糖尿病等的治疗剂和/或预防剂等,或其药学上可接受的盐等有用。
-
公开(公告)号:US20140163008A1
公开(公告)日:2014-06-12
申请号:US14236545
申请日:2011-08-03
IPC分类号: C07D495/04 , C07D471/04 , C07D487/04 , C07D413/14
CPC分类号: C07D495/04 , A61K31/335 , A61K31/4245 , A61K31/437 , A61K31/4439 , A61K31/454 , A61K31/4985 , A61K31/5025 , A61K31/519 , C07D413/14 , C07D471/04 , C07D487/04
摘要: A dibenzoxepin derivative represented by the following general formula (I) wherein Y is a hydrogen atom and the like, RA is a hydrogen atom and the like, X is the formula (b3) wherein RB is a hydrogen atom and the like, and the like, A is the formula (a18) wherein R1 is a hydrogen atom and the like, and RC and RD are the same or different and each is a hydrogen atom and the like, and the like, which has a PPARγ agonist activity and the like, and useful as a therapeutic agent and/or prophylaxis agent and the like for type 2 diabetes and the like, or a pharmaceutically acceptable salt thereof and the like is provided.
摘要翻译: 由以下通式(I)表示的二苯并氧杂环己烷衍生物,其中Y为氢原子等,RA为氢原子等,X为式(b3),其中RB为氢原子等, A是式(a18),其中R1是氢原子等,RC和RD相同或不同,各自是具有PPARγ激动剂活性的氢原子等,以及 作为2型糖尿病等的治疗剂和/或预防剂等,或其药学上可接受的盐等有用。
-