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    Process for preparing optically active oxazolidinone derivative
    1.
    发明授权
    Process for preparing optically active oxazolidinone derivative 失效
    光学活性恶唑烷酮衍生物的制备方法

    公开(公告)号：US06403804B1

    公开(公告)日：2002-06-11

    申请号：US09456950

    申请日：1999-12-07

    申请人： Kenzo Sumi ,  Takashi Imai ,  Shigeru Mitsuhashi ,  Hideki Nara ,  Takashi Miura

    发明人： Kenzo Sumi ,  Takashi Imai ,  Shigeru Mitsuhashi ,  Hideki Nara ,  Takashi Miura

    IPC分类号： C07D26304

    CPC分类号： C07D263/20 ,  C07D263/22 ,  C07D263/24

    摘要： Disclosed is a process for preparing an optically active oxazolidinone derivative comprising allowing hydrazine to react on an optically active ester having a hydroxyl group at the 3-position which is represented by formula (II): wherein R1 represents a lower alkyl group having 1 to 4 carbon atoms, a phenyl group, a methoxymethyl group, a benzyloxymethyl group, a benzyloxycarbonylaminomethyl group which may have a substituent or substituents on the benzene ring thereof, an acylaminomethyl group having 3 to 10 carbon atoms, or an alkyloxycarbonylaminomethyl group having 3 to 6 carbon atoms; R2 and R3, which may be the same or different, each represent a hydrogen atom, a lower alkyl group having 1 to 4 carbon atoms, a phenyl group, an acetylaminomethyl group, a benzoylaminomethyl group, or a benzyl group; and * indicates an asymmetric carbon atom, and subjecting the resulting hydrazide to Curtius rearrangement.

    摘要翻译： 公开了一种制备光学活性恶唑烷酮衍生物的方法，其包括使肼在由式（II）表示的3-位具有羟基的光学活性酯上反应：其中R1表示具有1-4个碳原子的低级烷基 碳原子，苯基，甲氧基甲基，苄氧基甲基，苯环上可以具有取代基的苄氧羰基氨基甲基，碳原子数3〜10的酰氨基甲基或碳原子数3〜6的烷氧基羰基氨基甲基 原子 R 2和R 3可以相同或不同，分别表示氢原子，碳原子数1〜4的低级烷基，苯基，乙酰氨基甲基，苯甲酰基氨基甲基或苄基。 和*表示不对称碳原子，并将所得酰肼进行柯氏重排。

    Process for producing optically active benzhydrol compounds
    3.
    发明授权
    Process for producing optically active benzhydrol compounds 失效
    光学活性二苯甲醇化合物的制备方法

    公开(公告)号：US5780692A

    公开(公告)日：1998-07-14

    申请号：US772525

    申请日：1996-12-24

    申请人： Minzo Sakaguchi ,  Takashi Imai ,  Takashi Miura ,  Tetsuro Yamazaki

    发明人： Minzo Sakaguchi ,  Takashi Imai ,  Takashi Miura ,  Tetsuro Yamazaki

    IPC分类号： B01J31/02 ,  B01J31/24 ,  B01J31/26 ,  C07B53/00 ,  C07B61/00 ,  C07C29/145 ,  C07C33/18 ,  C07C33/24 ,  C07C33/46 ,  C07C39/12 ,  C07C67/31 ,  C07C69/76 ,  C07C33/34 ,  C07C35/21 ,  C07C35/22

    CPC分类号： C07C29/145 ,  C07C69/76

    摘要： A process for producing a benzhydrol compound (II) which comprises hydrogenating a benzophenone compound (I) in the presence of a hydrogenation catalyst consisting of a transition metal complex, a base and an optically active diamine compound: ##STR1## wherein R.sup.1 to R.sup.10 each represents H, OH, C.sub.1-4 alkyl, C.sub.1-4 alkoxy, C.sub.1-4 alkanoyl, etc., R.sup.2 and R.sup.3, and R.sup.8 and R.sup.9 may form --CH.dbd.CH--CH.dbd.CH--, or any two of R.sup.1 to R.sup.9 adjacent to each other may be bonded to thereby form --OCH.sub.2 O-- or --(CH.sub.2).sub.3 --. By using this process, optically active benzhydrol compounds which have a high purity and are useful as, for example, intermediates in the synthesis of drugs can be produced by simple procedures.

    摘要翻译： 一种二苯甲醇化合物（II）的制备方法，其包括在由过渡金属配合物，碱和光学活性二胺化合物组成的氢化催化剂存在下氢化二苯甲酮化合物（I）：（I） （II）其中R 1至R 10各自表示H，OH，C 1-4烷基，C 1-4烷氧基，C 1-4烷酰基等，R 2和R 3，以及R 8和R 9可以形成-CH = CH-CH = CH - 或相邻的R 1至R 9中的任何两个可以键合，从而形成-OCH 2 O-或 - （CH 2）3 - 。 通过使用该方法，可以通过简单的方法制备具有高纯度并且可用作例如药物合成中的中间体的光学活性二苯甲基化合物。

    AUTOMATIC DOOR SENSOR AND FUNCTIONALITY EXPANSION MODULE FOR USE IN THE SAME
    4.
    发明申请
    AUTOMATIC DOOR SENSOR AND FUNCTIONALITY EXPANSION MODULE FOR USE IN THE SAME 有权
    自动门传感器和功能扩展模块用于其中

    公开(公告)号：US20130214930A1

    公开(公告)日：2013-08-22

    申请号：US13881809

    申请日：2011-10-27

    申请人： Masanao Shiraishi ,  Takashi Imai ,  Takashi Kondo ,  Takayasu Ikeda ,  Yohei Iwata

    发明人： Masanao Shiraishi ,  Takashi Imai ,  Takashi Kondo ,  Takayasu Ikeda ,  Yohei Iwata

    IPC分类号： G08B5/00 ,  H05K5/00

    CPC分类号： G08B5/00 ,  E05F15/43 ,  E05F15/74 ,  E05Y2900/132 ,  G01V8/20 ,  H05K5/0021

    摘要： An automatic door sensor includes: at least one sensor module unit (sensor module 11) configured to detect optically an object or a human body and to output, according to the detection results, a signal to a door controller for controlling an automatic door to open/close; an accommodation unit (profile 12) capable of accommodating the at least one sensor module unit; a cover member (front cover 13) that is transmissive to light for use for the detection performed by the sensor module unit and configured to cover the accommodation unit in which the sensor module unit is accommodated; and a functionality expansion module (LED module 14) either side of which can be joined to the cover member and that is configured to expand functionalities of the automatic door sensor by performing communication with the sensor module unit.

    摘要翻译： 自动门传感器包括：至少一个传感器模块单元（传感器模块11），被配置为光学地检测物体或人体，并根据检测结果向门控制器输出信号，以控制自动门打开 /关; 能够容纳至少一个传感器模块单元的容纳单元（轮廓12）; 覆盖构件（前盖13），其对于由传感器模块单元执行的用于检测的光可透射并且被配置为覆盖其中容纳传感器模块单元的容纳单元; 以及功能扩展模块（LED模块14），其两侧可以连接到盖构件，并且被配置为通过与传感器模块单元进行通信来扩展自动门传感器的功能。

    Transfer ink jet recording aqueous ink
    5.
    发明授权
    Transfer ink jet recording aqueous ink 有权
    转印喷墨记录水性油墨

    公开(公告)号：US08362108B2

    公开(公告)日：2013-01-29

    申请号：US13080181

    申请日：2011-04-05

    申请人： Takashi Imai

    发明人： Takashi Imai

    IPC分类号： C09D11/10

    CPC分类号： C09D11/324 ,  C08K5/06 ,  C08L101/06

    摘要： An aqueous ink for a transfer ink jet recording method including applying to an intermediate transfer member a reaction liquid which forms an increased viscosity ink image by coming into contact with a coloring material in the ink, applying the ink to the intermediate transfer member by an ink jet device to form an intermediate image, and bringing a printing object into contact with the intermediate transfer member to transfer the image to the object. The aqueous ink contains a coloring material which is a polymer dispersion pigment dispersed in the aqueous medium with a polymer having a hydroxyl group in its structure as a dispersant, a nonionic surfactant which is an alcohol ether surfactant a 1% aqueous solution of which has a cloud point of 33° C. or less and which has a C4-C30 alkyl group and a propyleneoxy group in its structure, and an aqueous medium.

    摘要翻译： 一种用于转印喷墨记录方法的水性油墨，其特征在于，向中间转印部件施加通过与油墨中的着色材料接触形成增加粘度的油墨图像的反应液体，通过油墨将油墨施加到中间转印部件 喷墨装置形成中间图像，并且使打印对象与中间转印部件接触以将图像转印到对象。 水性油墨含有作为分散在其结构中具有羟基的聚合物作为分散剂的水性介质中分散的聚合物分散颜料的着色材料，1％水溶液中的醇醚表面活性剂的非离子表面活性剂，其具有 浊点为33℃以下，其结构中具有C4-C30烷基和丙烯氧基，以及水性介质。

    Aqueous ink, ink jet recording method, ink cartridge, recording unit and ink jet recording apparatus
    6.
    发明授权
    Aqueous ink, ink jet recording method, ink cartridge, recording unit and ink jet recording apparatus 失效
    水性墨水，喷墨记录方法，墨盒，记录单元和喷墨记录装置

    公开(公告)号：US08324293B2

    公开(公告)日：2012-12-04

    申请号：US11550464

    申请日：2006-10-18

    申请人： Takashi Imai ,  Shinichi Hakamada ,  Kenji Moribe ,  Masako Udagawa

    发明人： Takashi Imai ,  Shinichi Hakamada ,  Kenji Moribe ,  Masako Udagawa

    IPC分类号： C09D11/00

    CPC分类号： C09D11/322 ,  C09D11/326

    摘要： An aqueous ink comprising a polymer having hydroxyl groups and a pigment, which can provide images excellent in scratch resistance and highlighter resistance and can inhibit the seeping out phenomenon of the polymer and the deterioration of ejection characteristics even when it is stored for a long period of time. The aqueous ink comprises a polymer having hydroxyl groups, a pigment and a water-soluble organic solvent, wherein the water-soluble organic solvent comprises a poor medium for a polymer that is not adsorbed on the pigment (out of the polymer having hydroxyl groups), and wherein when the segment constituting the polymer that is not adsorbed on the pigment (out of the polymer having hydroxyl groups) is comprised of a segment A having hydroxyl groups and a segment B having no hydroxyl group, at least one of the poor medium is a good medium for either one of the segment A and the Segment B.

    摘要翻译： 包含具有羟基的聚合物和颜料的水性油墨，其可以提供耐刮擦性和耐高温性优异的图像，并且可以抑制聚合物的渗出现象和喷射特性的劣化，即使当其长时间储存​​时 时间。 水性油墨包括具有羟基的聚合物，颜料和水溶性有机溶剂，其中水溶性有机溶剂包含不吸附在颜料上的聚合物的不良介质（在具有羟基的聚合物中） 并且其中当构成未吸附在颜料（在具有羟基的聚合物中）的聚合物的链段由具有羟基的链段A和不具有羟基的链段B组成时，至少一种不良培养基 是段A和段B之一的良好介质。

    Aqueous ink, ink jet recording method, ink cartridge, recording unit and ink jet recording apparatus
    7.
    发明授权
    Aqueous ink, ink jet recording method, ink cartridge, recording unit and ink jet recording apparatus 有权
    水性墨水，喷墨记录方法，墨盒，记录单元和喷墨记录装置

    公开(公告)号：US08217097B2

    公开(公告)日：2012-07-10

    申请号：US13080816

    申请日：2011-04-06

    申请人： Masako Udagawa ,  Shinichi Hakamada ,  Takashi Imai ,  Kenji Moribe

    发明人： Masako Udagawa ,  Shinichi Hakamada ,  Takashi Imai ,  Kenji Moribe

    IPC分类号： C09D11/00 ,  B01J13/00 ,  C08L31/00 ,  B41J2/01 ,  G01D11/00 ,  G01D15/04

    CPC分类号： C09D11/326

    摘要： The invention provides an aqueous ink comprising a polymer having hydroxyl groups and a pigment, which can provide images excellent in scratch resistance and highlighter resistance and can inhibit the seeping out phenomenon of the polymer and the deterioration of storage stability and ejection characteristics even when it is stored for a long period of time. The aqueous ink comprises a polymer having hydroxyl groups and a pigment, wherein a proportion of a content of a polymer that is not adsorbed on the pigment out of the polymer having hydroxyl groups to the content of the pigment in the ink is 2.0 mass % or more, and a content (mass %) of the polymer that is not adsorbed on the pigment out of the polymer having hydroxyl groups is 0.20 mass % or less based on the total mass of the ink.

    摘要翻译： 本发明提供一种水性油墨，其包含具有羟基的聚合物和颜料，其可以提供耐刮擦性和耐高温性优异的图像，并且可以抑制聚合物的渗出现象以及储存稳定性和喷射特性的劣化，即使是 储存很长一段时间。 水性油墨包含具有羟基的聚合物和颜料，其中，从具有羟基的聚合物中未吸附在颜料上的聚合物的含量与油墨中颜料含量的比例为2.0质量％，或 更多，并且从具有羟基的聚合物中未吸附在颜料上的聚合物的含量（质量％）为基于油墨的总质量为0.20质量％以下。

    VOLTAGE CONVERSION APPARATUS AND ELECTRICAL LOAD DRIVING APPARATUS
    9.
    发明申请
    VOLTAGE CONVERSION APPARATUS AND ELECTRICAL LOAD DRIVING APPARATUS 有权
    电压转换装置和电力负载驱动装置

    公开(公告)号：US20110148370A1

    公开(公告)日：2011-06-23

    申请号：US12679617

    申请日：2009-09-08

    申请人： Koichi Mizutani ,  Shinji Sekido ,  Junzo Oe ,  Takayuki Naito ,  Takashi Imai ,  Kouichi Yamanoue ,  Shigeki Yamamoto

    发明人： Koichi Mizutani ,  Shinji Sekido ,  Junzo Oe ,  Takayuki Naito ,  Takashi Imai ,  Kouichi Yamanoue ,  Shigeki Yamamoto

    IPC分类号： G05F1/10

    CPC分类号： H02M7/003 ,  H02M3/158 ,  H02M7/538

    摘要： The present invention is related to a voltage conversion apparatus having a first loop circuit and a second loop circuit which share an inductance component, in which a current passes through the first and second loop circuits alternately in accordance with ON/OFF operation of a first switching element provided in the first loop circuit, characterized in that a direction of a magnetic field through the first loop circuit generated at the ON operation of the first switching element in the first loop circuit is the same as a direction of a magnetic field through the second loop circuit generated at the OFF operation of the first switching element in the first loop circuit subsequent to the ON operation.

    摘要翻译： 本发明涉及一种具有第一环路电路和第二环路电路的电压转换装置，该第一环路电路和第二环路电路共享电感分量，其中电流根据第一开关的接通/断开操作交替地通过第一和第二回路电路 元件，其特征在于，在第一回路电路中的第一开关元件的导通操作时产生的通过第一回路电路的磁场方向与通过第二回路的磁场的方向相同 在ON操作之后的第一回路中的第一开关元件的OFF操作下产生的环路电路。

    DNA CHIP FOR PREDICTION OF OCCURRENCE OF LATE ADVERSE REACTION IN URINARY ORGAN AFTER RADIOTHERAPY, AND METHOD FOR PREDICTION OF OCCURRENCE OF LATE ADVERSE REACTION IN URINARY ORGAN AFTER RADIO THERAPY USING THE SAME
    10.
    发明申请
    DNA CHIP FOR PREDICTION OF OCCURRENCE OF LATE ADVERSE REACTION IN URINARY ORGAN AFTER RADIOTHERAPY, AND METHOD FOR PREDICTION OF OCCURRENCE OF LATE ADVERSE REACTION IN URINARY ORGAN AFTER RADIO THERAPY USING THE SAME 审中-公开
    用于预测放射治疗后尿道反应性不良反应的DNA芯片，以及使用其进行无线电治疗后预防尿毒症反应最近的不良反应的方法

    公开(公告)号：US20100130376A1

    公开(公告)日：2010-05-27

    申请号：US12452500

    申请日：2008-07-07

    申请人： Takashi Imai ,  Mayumi Iwakawa ,  Eisei Oda

    发明人： Takashi Imai ,  Mayumi Iwakawa ,  Eisei Oda

    IPC分类号： C40B30/04 ,  C40B40/08

    CPC分类号： C12Q1/6883 ,  C12Q1/6837 ,  C12Q2600/106 ,  C12Q2600/142 ,  C12Q2600/156

    摘要： A DNA chip and a prediction method for predicting the occurrence of a late adverse reaction in a urinary organ after C-ion RT are provided. The DNA chip comprises a supporting means for supporting a DNA probe thereon, and a plurality of genetic markers supported on the supporting means. The prediction method comprises a first step of hybridizing a genetic marker with a labeled DNA prepared from a subject to be examined, a second step of identifying bases of both alleles of the labeled DNA hybridized with the genetic marker, and a third step of determining a genotype of the labeled DNA as a risk genotype if the combination of the identified bases corresponds to the specified combination, and predicting that the subject is predisposed to develop a late adverse reaction in a urinary organ after radiotherapy when the number of the risk genotypes is three or more and the subject is not predisposed to develop a late adverse reaction in a urinary organ after radiotherapy when the number of the risk genotypes is two or less. The method enables to predict whether or not a subject is affected with a late adverse reaction in a urinary organ after radiotherapy.

    摘要翻译： 提供DNA芯片和用于预测C-ion RT后的尿器官晚期不良反应发生的预测方法。 DNA芯片包括用于在其上支撑DNA探针的支撑装置和支撑在支撑装置上的多个遗传标记。 该预测方法包括：将遗传标记与由待检测对象制备的标记DNA杂交的第一步骤，鉴定与遗传标记杂交的标记DNA的两个等位基因的碱基的第二步骤，以及第三步骤， 如果所鉴定的碱基的组合对应于指定的组合，则标记的DNA的基因型为风险基因型，并且当风险基因型的数量为3时，预测该受试者易于在放射治疗后在尿器官中发展晚期不良反应 或以上，并且当风险基因型的数目为2或更小时，该受试者在放射治疗后不容易发生尿脏器官晚期不良反应。 该方法能够预测放射治疗后尿液器官的晚期不良反应是否影响受试者。