Process for producing toluidine compound
    4.
    发明授权
    Process for producing toluidine compound 有权
    甲苯胺化合物的制备方法

    公开(公告)号:US08338612B2

    公开(公告)日:2012-12-25

    申请号:US12671050

    申请日:2008-07-29

    IPC分类号: C07D213/74

    CPC分类号: C07D213/72

    摘要: Because fluazinam is excellent as an active ingredient of pesticides and highly useful, it is desired to produce it efficiently in a proper form with simple operations at low cost in an environmentally friendly manner. The desired product is obtained in good yields with simple operations by using industrially advantageous reaction systems by a process comprising (1) a step of reacting ACTF and DCDNBTF in the presence of an alkali component, a solvent selected from the group consisting of ketones, nitriles, ethers and esters and a sufficient amount of water to substantially dissolve the alkali component, (2) a step of neutralizing or acidifying the reaction mixture with an acid and (3) a step of removing the solvent by distillation from the mixture containing fluazinam as the reaction product and the reaction solvent to precipitate crystals the product.

    摘要翻译: 由于氟啶胺作为农药的有效成分是优异的,而且是非常有用的,因此希望能以低成本的环境友好的方式以简单的操作以适当的形式有效地生产。 通过使用工业上有利的反应体系,通过使用包括(1)在碱组分,选自酮,腈的溶剂存在下使ACTF和DCDNBTF反应的步骤,以简单的操作获得所需产物 ,醚和酯和足够量的水以基本上溶解碱组分,(2)用酸中和或酸化反应混合物的步骤和(3)通过蒸馏从包含氟啶胺的混合物中除去溶剂的步骤为 反应产物和反应溶剂使产物析出晶体。

    PROCESS FOR PRODUCING TOLUIDINE COMPOUND
    5.
    发明申请
    PROCESS FOR PRODUCING TOLUIDINE COMPOUND 有权
    生产托洛芬化合物的方法

    公开(公告)号:US20100197930A1

    公开(公告)日:2010-08-05

    申请号:US12671050

    申请日:2008-07-29

    IPC分类号: C07D213/36

    CPC分类号: C07D213/72

    摘要: Because fluazinam is excellent as an active ingredient of pesticides and highly useful, it is desired to produce it efficiently in a proper form with simple operations at low cost in an environmentally friendly manner. The desired product is obtained in good yields with simple operations by using industrially advantageous reaction systems by a process comprising (1) a step of reacting ACTF and DCDNBTF in the presence of an alkali component, a solvent selected from the group consisting of ketones, nitriles, ethers and esters and a sufficient amount of water to substantially dissolve the alkali component, (2) a step of neutralizing or acidifying the reaction mixture with an acid and (3) a step of removing the solvent by distillation from the mixture containing fluazinam as the reaction product and the reaction solvent to precipitate crystals the product.

    摘要翻译: 由于氟啶胺作为农药的有效成分是优异的,而且是非常有用的,因此希望能以低成本的环境友好的方式以简单的操作以适当的形式有效地生产。 通过使用工业上有利的反应体系,通过使用包括(1)在碱组分,选自酮,腈的溶剂存在下使ACTF和DCDNBTF反应的步骤,以简单的操作获得所需产物 ,醚和酯和足够量的水以基本上溶解碱组分,(2)用酸中和或酸化反应混合物的步骤和(3)通过蒸馏从包含氟啶胺的混合物中除去溶剂的步骤为 反应产物和反应溶剂使产物析出晶体。