公开(公告)号：US11766548B2

公开(公告)日：2023-09-26

申请号：US17153969

申请日：2021-01-21

Applicant: KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY ,  Industry-University Cooperation Foundation Hanyang University ERICA Campus

Inventor： Myoung-Ryul Ok ,  So Yeon Kim ,  Yoon Ki Joung ,  Yu Chan Kim ,  Hyun Kwang Seok ,  Hyung-Seop Han ,  Hojeong Jeon ,  Hyunseon Seo ,  Inho Kim ,  Kyoung Won Park ,  Yongwoo Chung ,  Jaekyun Kim

IPC: A61M37/00 ,  A61N5/06

CPC classification number: A61M37/0015 ,  A61N5/062 ,  A61M2037/0023 ,  A61M2037/0053

Abstract: Provided are phototherapeutic needle patches usable for phototherapy by using needle patches capable of injecting drugs or cosmetic substances to patients, and methods of manufacturing the same. A phototherapeutic needle patch may include a patch body attachable to skin of a patient, at least one microneedle protruding from the patch body, one end of the microneedle configured to deliver a drug through stratum corneum of the skin to inner tissues of the skin, and light grooves formed in a concave shape along a length direction of the microneedle in such a manner that therapeutic light radiated from a light source for phototherapy easily penetrates into the skin along the microneedle.

公开(公告)号：US09968712B1

公开(公告)日：2018-05-15

申请号：US15377372

申请日：2016-12-13

Applicant: Korea Institute of Science and Technology

Inventor： Dong Keun Han ,  Yoon Ki Joung ,  Eugene Lih ,  Yun Ah Kim

IPC: A61K9/00 ,  A61L27/58 ,  A61L27/56 ,  A61L27/10 ,  A61L27/54 ,  A61L27/34 ,  A61L27/18 ,  A61L27/36 ,  A61L27/26 ,  C12N5/00

CPC classification number: A61L27/58 ,  A61K9/0024 ,  A61L27/10 ,  A61L27/18 ,  A61L27/26 ,  A61L27/34 ,  A61L27/3633 ,  A61L27/54 ,  A61L27/56 ,  A61L2300/252 ,  A61L2300/412 ,  A61L2300/414 ,  A61L2400/18 ,  C12N5/0068 ,  C12N2533/90

Abstract: Provided is an organic/inorganic hybrid-porous biodegradable polymer scaffold, which includes basic ceramic nanoparticles, an animal tissue or cell-derived bioactive first extracellular matrix material, and a biodegradable polymer and in which inner walls of pores are coated with a second extracellular matrix material.

公开(公告)号：US08852624B2

公开(公告)日：2014-10-07

申请号：US13633342

申请日：2012-10-02

Applicant: Korea Institute of Science and Technology

Inventor： Dong Keun Han ,  Yoon Ki Joung ,  Jong Hee Kang ,  Ji Yeon Choi ,  Chang Hun Kum

IPC: A61K9/50 ,  A61K31/74

CPC classification number: A61L17/145 ,  A61L27/306 ,  A61L27/34 ,  A61L27/446 ,  A61L27/58 ,  A61L31/088 ,  A61L31/10 ,  A61L31/128 ,  A61L31/148 ,  A61L2420/04 ,  B82Y5/00 ,  C08L67/04

Abstract: A biomedical implant according to this invention comprises ceramic complex, which includes a surface-modified basic ceramic particles, which are basic ceramic particles modified their surface with first biodegradable polymers, and the second biodegradable polymers. The first and second biodegradable polymer are combined each other and form a stereo complex. The biomedical implant has a superior effect to suppress inflammation caused by degradation of biodegradable polymers with improving its mechanical property.

Abstract translation: 根据本发明的生物医学植入物包括陶瓷复合物，其包括表面改性的碱性陶瓷颗粒，其是用第一可生物降解聚合物改性其表面的碱性陶瓷颗粒和第二可生物降解聚合物。 第一和第二生物可降解聚合物彼此组合并形成立体复合物。 生物医学植入物具有优异的抑制可生物降解聚合物降解引起的炎症的作用，具有改善其机械性能。