摘要:
The invention relates to novel heterocyclic compounds and pharmaceutical preparations thereof. The invention further relates to methods of treating or preventing cancer using the novel heterocyclic compounds of the invention.
摘要:
The invention relates to novel heterocyclic compounds and pharmaceutical preparations thereof. The invention further relates to methods of treating or preventing cancer using the novel heterocyclic compounds of the invention.
摘要:
The invention relates to methods of treating cancer, myeloproliferative disorders or immunological diseases with a combination of an immunomodulatory agent and a glutaminase inhibitor. The invention further relates to methods of treating cancer, myeloproliferative disorders, or immunological diseases that are resistant to one or more immunomodulatory agents.
摘要:
Compounds having the formula (I) wherein R1, R2, R3 and X are as defined herein are Hepatitis C virus NS5b polymerase inhibitors. Also disclosed are compositions and methods for treating an HCV infection and inhibiting HCV replication.
摘要:
Compounds having the formula A-R wherein A is a heteroaryl and R is Ia, Ib or Ic and wherein A, R, R1, R2a, R2b, R2c, R3a, R3b, R4, R5, R6, Ra, Rb, Rc, Rd, X, X1, X2 and n are as are as defined herein are Hepatitis C virus NS5b polymerase inhibitors. Also disclosed are compositions and methods for treating an HCV infection and inhibiting HCV replication.R is
摘要:
Compounds having the formula I wherein A, R1, R2, R3, R4a, R4b, R4c, R5, R6, R7a, R7b, Ar1, Rc, Rd, Re, Rf, X, n and p are as defined herein are Hepatitis C virus NS5b polymerase inhibitors. Also disclosed are compositions and methods for treating an HCV infection and inhibiting HCV replication.
摘要:
Methods and systems for providing illumination of a specimen for a process performed on the specimen are provided. One system configured to provide illumination of a specimen for a process performed on the specimen includes a laser configured to generate excitation light. The system also includes focusing optics configured to focus the excitation light to a plasma in an electrodeless lamp such that the plasma generates light. The system is also configured such that the light illuminates the specimen during the process.
摘要:
Compounds having the formula I wherein R1, R2, R3, R4a, R4b, R4c, R5, R6, R9 and n are as defined herein are Hepatitis C virus NS5b polymerase inhibitors. Also disclosed are compositions and methods for treating an HCV infection and inhibiting HCV replication.
摘要:
Systems, computer readable media and methods for digital processing of images captured by a sensor to enhance intensity uniformity of the images. The sensor captures an image of a white light source. Then, using the captured image, a compensation factor for each pixel of the image sensor is calculated and stored in a memory. Next, an actual image is captured by the image sensor. Subsequently, the signal intensity of each pixel is modified using the corresponding compensation factor to enhance the uniformity of the actual image.
摘要:
There is provided an orthotic configured for muscle imbalance correction. The orthotic has a strapping configured for physically activating an undercompensating muscle group by physically pulling substantially in-line with muscle fibres of the undercompensating muscle group to assist muscle activation and physically deactivating an overcompensating muscle group by physically pulling and therefore compressing across muscle fibres of the overcompensating muscle group to provide muscle resistance. Examples of the undercompensating muscle group are at least one of the gluteus maximus, medius, and minimus, vastus medialis and vastus medialis oblique. Examples of the overcompensating muscle group are at least one of the tensor fascia latae and iliopsoas.