公开(公告)号：US20050155541A1

公开(公告)日：2005-07-21

申请号：US10513153

申请日：2003-04-08

申请人： Linda McCausland ,  David Reay

发明人： Linda McCausland ,  David Reay

IPC分类号： F26B17/10 ,  A61K9/16 ,  B01D1/18 ,  B01D9/00 ,  B01D9/02 ,  C07D499/18 ,  C07D499/46 ,  F26B3/12 ,  C30B1/00

CPC分类号： F26B3/12 ,  A61K9/1688 ,  B01D1/18 ,  B01D9/0027 ,  B01D9/005 ,  B01D9/0054 ,  B01D9/0059 ,  B01D9/0081 ,  Y10S117/901

摘要： Small crystals are made by mixing a solution of a desired substance with an anti-solvent in a fluidic vortex mixer in which the residence time is less than 1s, for example 10 ms. The liquid within the fluidic vortex mixer (12) is subjected to high intensity ultrasound from a transducer (20, 22). The solution very rapidly becomes supersaturated, and the ultrasound can induce a very large number of nuclei for crystal growth. Small crystals, for example less than 5 μm, are formed. The resulting suspension is treated so as to add or remove ingredients, and then spray dried using an atomiser tuned to create small droplets in such a way that each droplet should contain not more than one crystal. Crystal agglomeration is hence prevented.

摘要翻译： 通过将所需物质的溶液与抗溶剂混合在流动涡旋混合器中制备小晶体，其中停留时间小于1秒，例如10ms。 流体涡流混合器（12）内的液体经受来自换能器（20,22）的高强度超声波。 溶液非常迅速地变得过饱和，并且超声可以诱导非常大量的用于晶体生长的核。 形成小晶体，例如小于5μm。 处理所得悬浮液以便添加或除去成分，然后使用调节的雾化器喷雾干燥以产生小液滴，使得每个液滴应包含不超过一个晶体。 因此防止了晶体聚集。

公开(公告)号：US20170215415A1

公开(公告)日：2017-08-03

申请号：US15416748

申请日：2017-01-26

申请人： David Reay

发明人： David Reay

IPC分类号： A01N33/12 ,  A61L2/18 ,  A61L2/22 ,  C11D3/30 ,  C11D3/48 ,  A01N25/16 ,  C11D3/20 ,  C11D1/66 ,  C11D3/33 ,  A01N25/08 ,  A01N25/02 ,  A61L2/23 ,  C11D3/39

CPC分类号： A01N33/12 ,  A61L2/18 ,  A61L2/22 ,  A61L2/23 ,  C11D1/62 ,  C11D1/72 ,  C11D1/835 ,  C11D3/2086 ,  C11D3/33 ,  C11D3/3917 ,  C11D3/3947 ,  C11D3/48 ,  A01N25/12 ,  A01N37/16 ,  A01N59/00

摘要： A composition that is useful for disinfecting surfaces, instruments, or equipment that may comprise an oxidizer precursor, a pH adjusting agent, an acetylating agent, a chelating agent, and a quaternary ammonium salt is described. The composition may be dispensed in a variety of ways, for example, such as a sprayed solution, a fog, or a foam.

公开(公告)号：US07326294B2

公开(公告)日：2008-02-05

申请号：US10513153

申请日：2003-04-08

申请人： Linda Jane McCausland ,  David Reay

发明人： Linda Jane McCausland ,  David Reay

IPC分类号： B01D9/00 ,  C30B1/00

CPC分类号： F26B3/12 ,  A61K9/1688 ,  B01D1/18 ,  B01D9/0027 ,  B01D9/005 ,  B01D9/0054 ,  B01D9/0059 ,  B01D9/0081 ,  Y10S117/901

摘要： Small crystals are made by mixing a solution of a desired substance with an anti-solvent in a fluidic vortex mixer in which the residence time is less than 1s, for example 10 ms. The liquid within the fluidic vortex mixer (12) is subjected to high intensity ultrasound from a transducer (20, 22). The solution very rapidly becomes supersaturated, and the ultrasound can induce a very large number of nuclei for crystal growth. Small crystals, for example less than 5 μm, are formed. The resulting suspension is treated so as to add or remove ingredients, and then spray dried using an atomizer tuned to create small droplets in such a way that each droplet should contain not more than one crystal. Crystal agglomeration is hence prevented.

摘要翻译： 通过将所需物质的溶液与抗溶剂混合在流动涡旋混合器中制备小晶体，其中停留时间小于1秒，例如10ms。 流体涡流混合器（12）内的液体经受来自换能器（20,22）的高强度超声波。 溶液非常迅速地变得过饱和，并且超声可以诱导非常大量的用于晶体生长的核。 形成小晶体，例如小于5μm。 处理所得到的悬浮液以便添加或除去成分，然后使用调节的雾化器喷雾干燥以产生小液滴，使得每个液滴应该包含不超过一个晶体。 因此防止了晶体聚集。