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公开(公告)号:US09814553B1
公开(公告)日:2017-11-14
申请号:US11870394
申请日:2007-10-10
申请人: Lothar Walter Kleiner , Yiwen Tang , Syed Faiyaz Ahmed Hossainy , Florencia Lim , Michael Ngo , Mikael Trollsas , Qing Lin
发明人: Lothar Walter Kleiner , Yiwen Tang , Syed Faiyaz Ahmed Hossainy , Florencia Lim , Michael Ngo , Mikael Trollsas , Qing Lin
IPC分类号: A61F2/00
CPC分类号: A61F2/00 , A61L31/10 , A61L31/148 , A61L31/16 , A61L2300/416 , C08L67/04
摘要: The present invention provides a semi-crystalline polymer for a coating on an implantable device for controlling release of drug and methods of making and using the same.
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2.
公开(公告)号:US20100209476A1
公开(公告)日:2010-08-19
申请号:US12466317
申请日:2009-05-14
CPC分类号: A61L31/10 , A61L31/148 , A61L31/16 , A61L2300/00 , A61L2300/604 , C08L67/04
摘要: The present invention provides a coating comprising a reservoir layer comprising a terpolymer comprising caprolactone and glycolide and a primer layer comprising an amorphous polymer on an implantable device and methods of making and using the same.
摘要翻译: 本发明提供一种包含储层的涂层,其包含含有己内酯和乙交酯的三元共聚物和在可植入装置上包含无定形聚合物的底漆层及其制备和使用的方法。
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3.
公开(公告)号:US08697113B2
公开(公告)日:2014-04-15
申请号:US12466317
申请日:2009-05-14
CPC分类号: A61L31/10 , A61L31/148 , A61L31/16 , A61L2300/00 , A61L2300/604 , C08L67/04
摘要: The present invention provides a coating comprising a reservoir layer comprising a terpolymer comprising caprolactone and glycolide and a primer layer comprising an amorphous polymer on an implantable device and methods of making and using the same.
摘要翻译: 本发明提供一种包含储层的涂层,其包含含有己内酯和乙交酯的三元共聚物和在可植入装置上包含无定形聚合物的底漆层及其制备和使用的方法。
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公开(公告)号:US20090041845A1
公开(公告)日:2009-02-12
申请号:US11891131
申请日:2007-08-08
申请人: Lothar Walter Kleiner , Jessica Renee DesNoyer , Bozena Zofia Maslanka , Mikael Trollsas , Syed F.A. Hossainy , Yiwen Tang , Thierry Glauser , Michael Ngo
发明人: Lothar Walter Kleiner , Jessica Renee DesNoyer , Bozena Zofia Maslanka , Mikael Trollsas , Syed F.A. Hossainy , Yiwen Tang , Thierry Glauser , Michael Ngo
IPC分类号: A61K9/00 , A61K31/436
CPC分类号: A61L31/10 , A61L31/16 , A61L2300/416 , A61L2300/602 , A61L2420/06
摘要: Disclosed herein is a coating having a layer that includes a matrix phase and a dispersed phase substantially immiscible in the matrix phase and methods of using the same.
摘要翻译: 本文公开了一种涂层,其具有包括基质相和在基质相中基本上不混溶的分散相的层及其使用方法。
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公开(公告)号:US08834556B2
公开(公告)日:2014-09-16
申请号:US13584678
申请日:2012-08-13
申请人: John E. Papp , Syed Faiyaz Ahmed Hossainy , Michael Ngo , Chad Abunassar , Boris Anukhin , Mikael Trollsas , Lewis B. Schwartz
发明人: John E. Papp , Syed Faiyaz Ahmed Hossainy , Michael Ngo , Chad Abunassar , Boris Anukhin , Mikael Trollsas , Lewis B. Schwartz
IPC分类号: A61F2/06
CPC分类号: A61F2/915 , A61F2/86 , A61F2/89 , A61F2/90 , A61F2/958 , A61F2002/826 , A61F2002/9155 , A61F2002/91591 , A61F2210/00 , A61F2230/0013 , A61F2230/0054 , A61F2240/001 , B29C35/0805 , B29C65/64 , B29C66/1248 , B29C66/71 , B29C2035/0838 , B29K2067/046 , B29K2995/006 , B29L2031/7534
摘要: Segmented scaffolds composed of disconnected scaffold segments with overlapping end rings are disclosed. Scaffolds with at least one discontinuous link are also disclosed.
摘要翻译: 公开了由具有重叠端环的断开的支架段组成的分段支架。 还公开了具有至少一个不连续链节的支架。
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公开(公告)号:US20140046431A1
公开(公告)日:2014-02-13
申请号:US13584678
申请日:2012-08-13
申请人: John E. Papp , Syed Faiyaz Ahmed Hossainy , Michael Ngo , Chad Abunassar , Boris Anukhin , Mikael Trollsas , Lewis B. Schwartz
发明人: John E. Papp , Syed Faiyaz Ahmed Hossainy , Michael Ngo , Chad Abunassar , Boris Anukhin , Mikael Trollsas , Lewis B. Schwartz
IPC分类号: A61F2/89
CPC分类号: A61F2/915 , A61F2/86 , A61F2/89 , A61F2/90 , A61F2/958 , A61F2002/826 , A61F2002/9155 , A61F2002/91591 , A61F2210/00 , A61F2230/0013 , A61F2230/0054 , A61F2240/001 , B29C35/0805 , B29C65/64 , B29C66/1248 , B29C66/71 , B29C2035/0838 , B29K2067/046 , B29K2995/006 , B29L2031/7534
摘要: Segmented scaffolds composed of disconnected scaffold segments with overlapping end rings are disclosed. Scaffolds with at least one discontinuous link are also disclosed.
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公开(公告)号:US20090306120A1
公开(公告)日:2009-12-10
申请号:US12436276
申请日:2009-05-06
申请人: Florencia Lim , Mikael Trollsas , Michael Ngo , Jie Hu , Lothar W. Kleiner , Yiwen Tang
发明人: Florencia Lim , Mikael Trollsas , Michael Ngo , Jie Hu , Lothar W. Kleiner , Yiwen Tang
IPC分类号: A61K47/34 , C08G63/08 , A61K31/436 , A61K31/337 , A61P9/00
CPC分类号: A61L31/10 , A61L31/16 , A61L2300/416 , A61L2300/602 , C08L67/04
摘要: The present invention provides an amorphous terpolymer for a coating on an implantable device for controlling release of drug and methods of making and using the same.
摘要翻译: 本发明提供用于控制药物释放的可植入装置上的涂层的无定形三元共聚物及其制备和使用方法。
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公开(公告)号:US09119787B2
公开(公告)日:2015-09-01
申请号:US12806790
申请日:2010-08-19
申请人: Florencia Lim , Mikael Trollsas , Michael Ngo , Thierry Glauser , Jinping Wan
发明人: Florencia Lim , Mikael Trollsas , Michael Ngo , Thierry Glauser , Jinping Wan
CPC分类号: A61K9/1647 , A61K9/0019 , A61K9/5031
摘要: Microparticle-bioactive agent based treatments for local treatment of diseased tissues/organs are disclosed.
摘要翻译: 公开了用于局部治疗病变组织/器官的基于微粒 - 生物活性剂的治疗方法。
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9.
公开(公告)号:US08697110B2
公开(公告)日:2014-04-15
申请号:US12466302
申请日:2009-05-14
申请人: Mikael Trollsas , Michael Ngo , Florencia Lim
发明人: Mikael Trollsas , Michael Ngo , Florencia Lim
摘要: The present invention provides an implantable article comprising an amorphous terpolymer and a semi-crystalline polymer. The amorphous terpolymer can be admixed with the semi-crystalline polymer or form a block copolymer with the semi-crystalline polymer.
摘要翻译: 本发明提供一种包含无定形三元共聚物和半结晶聚合物的可植入制品。 无定形三元共聚物可与半结晶聚合物混合,或与半结晶聚合物形成嵌段共聚物。
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10.
公开(公告)号:US20100291175A1
公开(公告)日:2010-11-18
申请号:US12466302
申请日:2009-05-14
申请人: MIKAEL TROLLSAS , Michael Ngo , Florencia Lim
发明人: MIKAEL TROLLSAS , Michael Ngo , Florencia Lim
摘要: The present invention provides an implantable article comprising an amorphous terpolymer and a semi-crystalline polymer. The amorphous terpolymer can be admixed with the semi-crystalline polymer or form a block copolymer with the semi-crystalline polymer.
摘要翻译: 本发明提供一种包含无定形三元共聚物和半结晶聚合物的可植入制品。 无定形三元共聚物可与半结晶聚合物混合,或与半结晶聚合物形成嵌段共聚物。
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