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1.Indane acetic acid derivatives and their use as pharmaceutical agents, intermediates, and method of preparation 失效
标题翻译: 茚基乙酸衍生物及其作为药剂,中间体和制备方法的用途公开(公告)号:US20100204472A1
公开(公告)日:2010-08-12
申请号:US12759328
申请日:2010-04-13
申请人: Louis-David Cantin , Soongyu Choi , Roger B. Clark , Martin F. Hentemann , Xin Ma , Joachim Rudolph , Sidney X. Liang , Christiana Akuche , Rico C. Lavoie , Libing Chen , Dyuti Majumdar , Philip L. Wickens
发明人: Louis-David Cantin , Soongyu Choi , Roger B. Clark , Martin F. Hentemann , Xin Ma , Joachim Rudolph , Sidney X. Liang , Christiana Akuche , Rico C. Lavoie , Libing Chen , Dyuti Majumdar , Philip L. Wickens
IPC分类号: C07D239/34 , C07D401/04 , C07D405/10 , C07D213/85 , C07D213/72 , C07D213/55 , C07D513/04 , C07D277/30 , C07D239/42
CPC分类号: C07D213/30 , C07C59/72 , C07C59/90 , C07C69/734 , C07C211/48 , C07C217/24 , C07C255/54 , C07C327/48 , C07C333/04 , C07C2602/08 , C07D209/08 , C07D213/63 , C07D213/83 , C07D213/84 , C07D215/20 , C07D231/12 , C07D239/26 , C07D239/42 , C07D239/46 , C07D239/47 , C07D239/52 , C07D249/06 , C07D249/08 , C07D261/20 , C07D263/32 , C07D263/56 , C07D277/24 , C07D277/34 , C07D277/56 , C07D277/64 , C07D277/66 , C07D285/08 , C07D307/42 , C07D307/79 , C07D333/16 , C07D405/04 , C07D417/04 , C07D513/04
摘要: This invention relates to novel indane acetic acid derivatives which are useful in the treatment of diseases such as diabetes, obesity, hyperlipidemia, and atherosclerotic diseases. The invention also relates to intermediates useful in preparation of indane acetic derivatives and to methods of preparation.
摘要翻译: 本发明涉及可用于治疗疾病如糖尿病,肥胖症,高脂血症和动脉粥样硬化疾病的新型茚满乙酸衍生物。 本发明还涉及可用于制备茚满乙酸衍生物的中间体及其制备方法。
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2.Indane acetic acid derivatives and their use as pharmaceutical agents, intermediates, and method of preparation 失效
标题翻译: 茚基乙酸衍生物及其作为药剂,中间体和制备方法的用途公开(公告)号:US07906653B2
公开(公告)日:2011-03-15
申请号:US12759328
申请日:2010-04-13
申请人: Louis-David Cantin , Soongyu Choi , Roger B. Clark , Martin F. Hentemann , Xin Ma , Joachim Rudolph , Sidney X. Liang , Christiana Akuche , Rico C. Lavoie , Libing Chen , Dyuti Majumdar , Philip L. Wickens
发明人: Louis-David Cantin , Soongyu Choi , Roger B. Clark , Martin F. Hentemann , Xin Ma , Joachim Rudolph , Sidney X. Liang , Christiana Akuche , Rico C. Lavoie , Libing Chen , Dyuti Majumdar , Philip L. Wickens
IPC分类号: C07D277/20
CPC分类号: C07D213/30 , C07C59/72 , C07C59/90 , C07C69/734 , C07C211/48 , C07C217/24 , C07C255/54 , C07C327/48 , C07C333/04 , C07C2602/08 , C07D209/08 , C07D213/63 , C07D213/83 , C07D213/84 , C07D215/20 , C07D231/12 , C07D239/26 , C07D239/42 , C07D239/46 , C07D239/47 , C07D239/52 , C07D249/06 , C07D249/08 , C07D261/20 , C07D263/32 , C07D263/56 , C07D277/24 , C07D277/34 , C07D277/56 , C07D277/64 , C07D277/66 , C07D285/08 , C07D307/42 , C07D307/79 , C07D333/16 , C07D405/04 , C07D417/04 , C07D513/04
摘要: This invention relates to novel indane acetic acid derivatives which are useful in the treatment of diseases such as diabetes, obesity, hyperlipidemia, and atherosclerotic diseases. The invention also relates to intermediates useful in preparation of indane acetic derivatives and to methods of preparation.
摘要翻译: 本发明涉及可用于治疗疾病如糖尿病,肥胖症,高脂血症和动脉粥样硬化疾病的新型茚满乙酸衍生物。 本发明还涉及可用于制备茚满乙酸衍生物的中间体和制备方法。
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公开(公告)号:US07714004B2
公开(公告)日:2010-05-11
申请号:US10537630
申请日:2003-12-19
申请人: Louis-David Cantin , Soongyu Choi , Roger B. Clark , Martin F. Hentemann , Xin Ma , Joachim Rudolph , Sidney X. Liang , Christiana Akuche , Rico C. Lavoie , Libing Chen , Dyuti Majumdar , Philip L. Wickens
发明人: Louis-David Cantin , Soongyu Choi , Roger B. Clark , Martin F. Hentemann , Xin Ma , Joachim Rudolph , Sidney X. Liang , Christiana Akuche , Rico C. Lavoie , Libing Chen , Dyuti Majumdar , Philip L. Wickens
IPC分类号: A61K31/426 , C07D277/20
CPC分类号: C07D213/30 , C07C59/72 , C07C59/90 , C07C69/734 , C07C211/48 , C07C217/24 , C07C255/54 , C07C327/48 , C07C333/04 , C07C2602/08 , C07D209/08 , C07D213/63 , C07D213/83 , C07D213/84 , C07D215/20 , C07D231/12 , C07D239/26 , C07D239/42 , C07D239/46 , C07D239/47 , C07D239/52 , C07D249/06 , C07D249/08 , C07D261/20 , C07D263/32 , C07D263/56 , C07D277/24 , C07D277/34 , C07D277/56 , C07D277/64 , C07D277/66 , C07D285/08 , C07D307/42 , C07D307/79 , C07D333/16 , C07D405/04 , C07D417/04 , C07D513/04
摘要: This invention relates to novel indane acetic acid derivatives which are useful in the treatment of diseases such as diabetes, obesity, hyperlipidemia, and atherosclerotic diseases. The invention also relates to intermediates useful in preparation of indane acetic derivatives and to methods of preparation.
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公开(公告)号:US20060084680A1
公开(公告)日:2006-04-20
申请号:US10537630
申请日:2003-12-19
申请人: Louis-David Cantin , Soongyu Choi , Roger Clark , Martin Hentemann , Xin Ma , Joachim Rudolph , Sidney Liang , Christiana Akuche , Rico Lavoie , Libing Chen , Dyuti Majumdar , Philip Wickens
发明人: Louis-David Cantin , Soongyu Choi , Roger Clark , Martin Hentemann , Xin Ma , Joachim Rudolph , Sidney Liang , Christiana Akuche , Rico Lavoie , Libing Chen , Dyuti Majumdar , Philip Wickens
IPC分类号: A61K31/445 , A61K31/195 , A61K31/192
CPC分类号: C07D213/30 , C07C59/72 , C07C59/90 , C07C69/734 , C07C211/48 , C07C217/24 , C07C255/54 , C07C327/48 , C07C333/04 , C07C2602/08 , C07D209/08 , C07D213/63 , C07D213/83 , C07D213/84 , C07D215/20 , C07D231/12 , C07D239/26 , C07D239/42 , C07D239/46 , C07D239/47 , C07D239/52 , C07D249/06 , C07D249/08 , C07D261/20 , C07D263/32 , C07D263/56 , C07D277/24 , C07D277/34 , C07D277/56 , C07D277/64 , C07D277/66 , C07D285/08 , C07D307/42 , C07D307/79 , C07D333/16 , C07D405/04 , C07D417/04 , C07D513/04
摘要: This invention relates to novel indane acetic acid derivatives which are useful in the treatment of diseases such as diabetes, obesity, hyperlipidemia, and atherosclerotic diseases. The invention also relates to intermediates useful in preparation of indane acetic derivatives and to methods of preparation.
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公开(公告)号:US07265144B2
公开(公告)日:2007-09-04
申请号:US10719485
申请日:2003-11-21
申请人: Joachim Rudolph , Louis-David Cantin , Steven Magnuson , William Bullock , Ann-Marie Bullion , Libing Chen , Chih-Yuan Chuang , Sidney Liang , Dyuti Majumdar , Herbert Ogutu , Alan Olague , Ning Qi , Philip L. Wickens
发明人: Joachim Rudolph , Louis-David Cantin , Steven Magnuson , William Bullock , Ann-Marie Bullion , Libing Chen , Chih-Yuan Chuang , Sidney Liang , Dyuti Majumdar , Herbert Ogutu , Alan Olague , Ning Qi , Philip L. Wickens
IPC分类号: A61K31/4152 , C07D231/44
CPC分类号: C07D231/38 , C07D401/04 , C07D403/12 , C07D413/12 , C07D471/04
摘要: The present invention relates to anilinopyrazole compounds, pharmaceutical compositions, and methods for treating diabetes and related disorders.
摘要翻译: 本发明涉及苯胺基吡唑化合物,药物组合物和治疗糖尿病及相关疾病的方法。
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6.
公开(公告)号:US20080064734A1
公开(公告)日:2008-03-13
申请号:US11897620
申请日:2007-08-31
申请人: Joachim Rudolph , Louis-David Cantin , Steven Magnuson , William Bullock , Ann-Marie Bullion , Libing Chen , Chih-Yuan Chuang , Sidney Liang , Dyuti Majumdar , Herbert Ogutu , Alan Olague , Ning Qi , Philip Wickens
发明人: Joachim Rudolph , Louis-David Cantin , Steven Magnuson , William Bullock , Ann-Marie Bullion , Libing Chen , Chih-Yuan Chuang , Sidney Liang , Dyuti Majumdar , Herbert Ogutu , Alan Olague , Ning Qi , Philip Wickens
IPC分类号: A61K31/415 , A61P3/04 , C07D231/10
CPC分类号: C07D231/38 , C07D401/04 , C07D403/12 , C07D413/12 , C07D471/04
摘要: The present invention relates to anilinopyrazole compounds, pharmaceutical compositions, and methods for treating diabetes and related disorders.
摘要翻译: 本发明涉及苯胺基吡唑化合物,药物组合物和治疗糖尿病及相关疾病的方法。
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7.
公开(公告)号:US07964622B2
公开(公告)日:2011-06-21
申请号:US12508314
申请日:2009-07-23
申请人: Xin Ma , Louis-David Cantin , Soongyu Choi , Roger Clark , Martin Hentemann , Joachim Rudolph , Rico Lavoie , Zhonghua Zhang
发明人: Xin Ma , Louis-David Cantin , Soongyu Choi , Roger Clark , Martin Hentemann , Joachim Rudolph , Rico Lavoie , Zhonghua Zhang
IPC分类号: A61K31/425 , A61K31/42 , C07D417/00 , C07D277/20 , C07D498/00 , C07D263/30
CPC分类号: C07D403/12 , C07D209/08 , C07D401/12 , C07D405/14 , C07D413/12 , C07D417/12 , C07D417/14 , C07D513/04
摘要: This invention is directed to indole acetic acid derivatives and their use in pharmaceutical compositions for the treatment of diseases such as diabetes, obesity, hyperlipidemia, and atherosclerotic disease. The invention is also directed to intermediates useful in preparation of indole acetic derivatives and to methods of preparation.
摘要翻译: 本发明涉及吲哚乙酸衍生物及其在药物组合物中用于治疗疾病如糖尿病,肥胖症,高脂血症和动脉粥样硬化疾病的用途。 本发明还涉及可用于制备吲哚乙酸衍生物的中间体和制备方法。
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公开(公告)号:US20060264486A1
公开(公告)日:2006-11-23
申请号:US10555024
申请日:2004-04-28
申请人: Xin Ma , Louis-David Cantin , Soongyu Choi , Roger Clark , Martin Hentemann , Joachim Rudolph , Rico Lavoie , Zhonghua Zhang
发明人: Xin Ma , Louis-David Cantin , Soongyu Choi , Roger Clark , Martin Hentemann , Joachim Rudolph , Rico Lavoie , Zhonghua Zhang
IPC分类号: A61K31/422 , C07D413/02
CPC分类号: C07D403/12 , C07D209/08 , C07D401/12 , C07D405/14 , C07D413/12 , C07D417/12 , C07D417/14 , C07D513/04
摘要: This invention is directed to indole acetic acid derivatives and their use in pharmaceutical compositions for the treatment of diseases such as diabetes, obesity, hyperlipidemia, and atherosclerotic disease. The invention is also directed to intermediates useful in preparation of indole acetic derivatives and to methods of preparation.
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公开(公告)号:US20090298854A1
公开(公告)日:2009-12-03
申请号:US12508314
申请日:2009-07-23
申请人: Xin Ma , Louis-David Cantin , Soongyu Choi , Roger Clark , Martin Hentemann , Joachim Rudolph , Rico Lavoie , Zhonghua Zhang
发明人: Xin Ma , Louis-David Cantin , Soongyu Choi , Roger Clark , Martin Hentemann , Joachim Rudolph , Rico Lavoie , Zhonghua Zhang
IPC分类号: A61K31/497 , C07D261/20 , A61K31/42 , C07D263/30 , A61K31/422 , C07D401/10 , A61P3/10
CPC分类号: C07D403/12 , C07D209/08 , C07D401/12 , C07D405/14 , C07D413/12 , C07D417/12 , C07D417/14 , C07D513/04
摘要: This invention is directed to indole acetic acid derivatives and their use in pharmaceutical compositions for the treatment of diseases such as diabetes, obesity, hyperlipidemia, and atherosclerotic disease. The invention is also directed to intermediates useful in preparation of indole acetic derivatives and to methods of preparation.
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10.
公开(公告)号:US07592361B2
公开(公告)日:2009-09-22
申请号:US10555024
申请日:2004-04-28
申请人: Xin Ma , Louis-David Cantin , Soongyu Choi , Roger Clark , Martin Hentemann , Joachim Rudolph , Rico Lavoie , Zhonghua Zhang
发明人: Xin Ma , Louis-David Cantin , Soongyu Choi , Roger Clark , Martin Hentemann , Joachim Rudolph , Rico Lavoie , Zhonghua Zhang
IPC分类号: A61K31/425 , A61K31/42 , C07D417/00 , C07D277/20 , C07D498/00 , C07D263/30
CPC分类号: C07D403/12 , C07D209/08 , C07D401/12 , C07D405/14 , C07D413/12 , C07D417/12 , C07D417/14 , C07D513/04
摘要: This invention is directed to indole acetic acid derivatives and their use in pharmaceutical compositions for the treatment of diseases such as diabetes, obesity, hyperlipidemia, and atherosclerotic disease. The invention is also directed to intermediates useful in preparation of indole acetic derivatives and to methods of preparation.
摘要翻译: 本发明涉及吲哚乙酸衍生物及其在药物组合物中用于治疗疾病如糖尿病,肥胖症,高脂血症和动脉粥样硬化疾病的用途。 本发明还涉及可用于制备吲哚乙酸衍生物的中间体和制备方法。
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