摘要:
The present invention relates to an aerosol composition containing a carrier agent capable of recognizing and binding to inflammatory and tumor foci mobilizing macrophages in their immediate environment, and an aerosol substrate, characterized in that the said carrier agent consists of a polysaccharide compound selected from the compound D 25, extracted from the membrane proteoglycans of the bacterium Klebsiella pneumoniae and having a molecular weight of 30.+-.0.10 Kd, and the compound oxidized D 25 in which the galactofuranoser residue (Gal.sub.f) of the linear polysaccharide chain of D 25 has been converted to arabinose, and their amide, ester or ether type derivatives, as well as their quaternary ammonium derivatives and salts, and also the derivatives obtained by grafting of phosphatides.
摘要翻译:本发明涉及一种含有能够识别和结合其直接环境中的炎性和肿瘤灶动员巨噬细胞的载体剂的气溶胶组合物,以及气溶胶底物,其特征在于所述载体剂由选自化合物 D 25,从肺炎克雷伯菌细菌的膜蛋白聚糖中提取,分子量为30 +/- 0.10Kd,D 25的直链多糖链的半乳糖醛酸残基(Galf)已经被氧化的D 25 转化成阿拉伯糖,以及它们的酰胺,酯或醚型衍生物,以及它们的季铵衍生物和盐,以及通过磷脂接枝获得的衍生物。
摘要:
The present invention relates to a vaccinal complex containing a specific antigen. This is a vaccinal complex characterized in that it is composed of bacterial ribosomal RNA or fragments of bacterial ribosomal RNA on which are coupled from 1 to 5% by weight of a specific antigen of bacterial serotype. This complex may be used as a vaccine.
摘要:
This invention relates to a process for the preparation of purified bacterial membranal proteoglycans. The process comprises at least one step in which crude proteoglycans are treated in aqueous medium with a base or a hypobromite, followed by elimination of the excess reactant and the insoluble residue, the purified proteoglycans being present in aqueous solution. The thus obtained purified proteoglycans may be used as immunity adjuvants in vaccines without causing side-effects such as pyrogenic reactions.
摘要:
This invention relates to a process for the preparation of purified bacterial membranal proteoglycans. The process comprises at least one step in which crude proteoglycans are treated in aqueous medium with a base or a hypobromite, followed by elimination of the excess reactant and the insoluble residue, the purified proteoglycans being present in aqueous solution. The thus obtained purified proteoglycans may be used as immunity adjuvants in vaccines without causing side-effects such as pyrogenic reactions.
摘要:
This invention relates to a non-specific immunostimulating preparation for the treatment of immunodeficits, such as those encountered in leprosy and cancer, characterized in that it contains as sole active principle one or more bacterial ribosomal RNA's extracted from the following strains:Klebsiella pneumoniaeSerratia marcescens
摘要:
A process for obtaining a plasminogen activator involves treating an acetone extract powder of organs of animals, such as the lungs and kidneys of pigs, calves, bullocks, horses, lambs or sheep or the ovaries of porcine, bovine or ovine animals, by suspension in an aqueous saline solution, taking up the precipitate obtained in an aqueous saline solution of greater ionic strength and lower pH-value, decanting the solution and precipitating therefrom at acidic pH by adding a salt or an organic solvent, further taking up the precipitate obtained in water or a saline solution, followed by repeated precipitation by adding a salt at a somewhat higher pH-value, finally taking up the precipitate obtained in water and dialyzing the solution, and optionally purifying the solution obtained.The activator obtained may be used as a medicament.
摘要:
The present invention relates to a pharmaceutical composition comprising a plasminogen activator and a polysaccharide sulphate. The invention also covers a process for preparing the pharmaceutical composition and a process for preparing the plasminogen activator.The pharmaceutical compositions are useful in the treatment of circulatory disorders such as venous thromboses.
摘要:
A rimlock for use with an eyeglass frame is provided. The rimlock comprises a pair of flanges which protrude from the frame at a split therein. A spring is fed through a bore passing through the flanges whereby a portion of the spring internal to the rimlock at a widened portion of the bore is in tension thereby biasing the flanges into engagement allowing the frame to hold a lens in position within the frame. By pulling the flanges apart, the lens can be removed.
摘要:
A rimlock for use with an eyeglass frame is provided. The rimlock comprises a pair of flanges which protrude from the frame at a split therein. A spring is fed through a bore passing through the flanges whereby a portion of the spring internal to the rimlock at a widened portion of the bore is in tension thereby biasing the flanges into engagement allowing the frame to hold a lens in position within the frame. By pulling the flanges apart, the lens can be removed.
摘要:
Adjustable flow electromagnetic valve having a closing assembly (8) movable within a chamber (7) with a passage (3) linked to a high pressure area and a passage (4) linked to a low pressure area. The electromagnetic valve is designed such that the closing assembly consists of a valve (8) freely movable within the chamber (7). The disk-shaped valve (8) is flat, light and non-deformable and is capable of being automatically brought to its fluid flow position when pressure within the inlet passage (HP) (5) tends to a value approaching a predefined set pressure; the electromagnetic valve is also designed such that fluid flow through the valve (8) is achieved by openings (10) formed in the thickness of the valve, the openings being arranged in a median area outside the circumference of the inlet passage (3) so that the latter can be closed when the valve (8) is electromagnetically returned. It is further characterized by adjusting the electromagnetic return force exerted by the electromagnet for placing the valve (8) at a predetermined point between opening and closing to provide a predetermined constant flow, and for alternately shifting it, according to a predetermined frequency, to provide an adjustable alternating flow of the same frequency and of variable amplitude, resulting in sequential, pulsed, rhythmic operation.