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公开(公告)号：US20080145321A1
公开(公告)日：2008-06-19
申请号：US12036674
申请日：2008-02-25
CPC分类号： A61K8/8176 , A61K8/0208 , A61K8/22 , A61K8/24 , A61K8/49 , A61K8/817 , A61K8/891 , A61K8/90 , A61K2800/805 , A61Q11/00 , A61Q11/02
摘要： Oral care compositions comprising: (a) a peroxide complex comprising a peroxide component and an N-vinyl heterocyclic polymer (e.g., poly-N-vinyl polylactam, or poly-N-vinyl-polyimide); (b) a whitening agent (e.g., hydrogen peroxide); and (c) an orally acceptable carrier. In one embodiment, the carrier comprises a film forming material. Methods are also provided for making an oral care composition comprising: (a) mixing a whitening agent, silicone adhesive and carrier fluid to form a homogenous mixture; (b) adding a peroxide complex to said homogenous mixture, wherein said complex comprises hydrogen peroxide and an N-vinyl heterocyclic polymer; and (c) mixing under vacuum.
摘要翻译： 口腔护理组合物，其包含：（a）包含过氧化物组分和N-乙烯基杂环聚合物（例如聚-N-乙烯基聚内酰胺或聚-N-乙烯基 - 聚酰亚胺）的过氧化物络合物; （b）增白剂（例如过氧化氢）; 和（c）口头可接受的承运人。 在一个实施方案中，载体包括成膜材料。 还提供了用于制备口腔护理组合物的方法，其包括：（a）将增白剂，硅氧烷粘合剂和载体流体混合以形成均匀的混合物; （b）向所述均匀混合物中加入过氧化物络合物，其中所述络合物包含过氧化氢和N-乙烯基杂环聚合物; 和（c）在真空下混合。
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公开(公告)号：US08540971B2
公开(公告)日：2013-09-24
申请号：US12036674
申请日：2008-02-25
CPC分类号： A61K8/8176 , A61K8/0208 , A61K8/22 , A61K8/24 , A61K8/49 , A61K8/817 , A61K8/891 , A61K8/90 , A61K2800/805 , A61Q11/00 , A61Q11/02
摘要： Oral care compositions comprising: (a) a peroxide complex comprising a peroxide component and an N-vinyl heterocyclic polymer (e.g., poly-N-vinyl polylactam, or poly-N-vinyl-polyimide); (b) a whitening agent (e.g., hydrogen peroxide); and (c) an orally acceptable carrier. In one embodiment, the carrier comprises a film forming material. Methods are also provided for making an oral care composition comprising: (a) mixing a whitening agent, silicone adhesive and carrier fluid to form a homogenous mixture; (b) adding a peroxide complex to said homogenous mixture, wherein said complex comprises hydrogen peroxide and an N-vinyl heterocyclic polymer; and (c) mixing under vacuum.
摘要翻译： 口腔护理组合物，其包含：（a）包含过氧化物组分和N-乙烯基杂环聚合物（例如聚-N-乙烯基聚内酰胺或聚-N-乙烯基 - 聚酰亚胺）的过氧化物络合物; （b）增白剂（例如过氧化氢）; 和（c）口头可接受的承运人。 在一个实施方案中，载体包括成膜材料。 还提供了用于制备口腔护理组合物的方法，其包括：（a）将增白剂，硅氧烷粘合剂和载体流体混合以形成均匀的混合物; （b）向所述均匀混合物中加入过氧化物络合物，其中所述络合物包含过氧化氢和N-乙烯基杂环聚合物; 和（c）在真空下混合。
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3.发明申请NON-AQUEOUS DENTIFRICE COMPOSITION WITH BIOACCEPTABLE AND BIOACTIVE GLASS AND METHODS OF USE AND MANUFACTURE THEREOF 有权不含生物玻璃和生物玻璃的非水性密度组合物及其使用和制造方法公开(公告)号：US20120020898A1
公开(公告)日：2012-01-26
申请号：US13260786
申请日：2010-04-01
摘要： The invention encompasses non-aqueous dentifrice compositions containing a bioacceptable and bioactive glass with improved mouth-feel, foam, and product stability. More particularly, the invention encompasses non-aqueous compositions including combinations including carrageenan and/or carboxymethylcellulose gums, glycerin, ethylene oxide/propylene oxide copolymers, and a bioactive glass and methods of use the compositions in an oral care product, for example, a whitening tooth-paste, for hypersensitive teeth.
摘要翻译： 本发明包括含有具有改善口感，泡沫和产品稳定性的生物可接受和生物活性玻璃的非水洁牙剂组合物。 更具体地说，本发明包括包括角叉菜胶和/或羧甲基纤维素胶，甘油，环氧乙烷/环氧丙烷共聚物和生物活性玻璃的组合的非水性组合物，以及在口腔护理产品中使用该组合物的方法，例如美白 牙膏，用于过敏牙齿。
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4.发明授权Non-aqueous dentifrice composition with bioacceptable and bioactive glass and methods of use and manufacture thereof 有权具有生物可接受和生物活性玻璃的非水洁牙剂组合物及其使用和制造方法公开(公告)号：US08741269B2
公开(公告)日：2014-06-03
申请号：US13260786
申请日：2010-04-01
摘要： The invention encompasses non-aqueous dentifrice compositions containing a bioacceptable and bioactive glass with improved mouth-feel, foam, and product stability. More particularly, the invention encompasses non-aqueous compositions including combinations including carrageenan and/or carboxymethylcellulose gums, glycerin, ethylene oxide/propylene oxide copolymers, and a bioactive glass and methods of use the compositions in an oral care product, for example, a whitening tooth-paste, for hypersensitive teeth.
摘要翻译： 本发明包括含有具有改善口感，泡沫和产品稳定性的生物可接受和生物活性玻璃的非水洁牙剂组合物。 更具体地说，本发明包括包括角叉菜胶和/或羧甲基纤维素胶，甘油，环氧乙烷/环氧丙烷共聚物和生物活性玻璃的组合的非水性组合物，以及在口腔护理产品中使用该组合物的方法，例如美白 牙膏，用于过敏牙齿。
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公开(公告)号：US20060045854A1
公开(公告)日：2006-03-02
申请号：US10929087
申请日：2004-08-27
IPC分类号： A61K8/22
CPC分类号： A61K8/8176 , A61K8/0208 , A61K8/22 , A61K8/24 , A61K8/49 , A61K8/817 , A61K8/891 , A61K8/90 , A61K2800/805 , A61Q11/00 , A61Q11/02
摘要： Oral care compositions comprising: (a) a peroxide complex comprising a peroxide component and an N-vinyl heterocyclic polymer (e.g., poly-N-vinyl polylactam, or poly-N-vinyl-polyimide); (b) a whitening agent (e.g., hydrogen peroxide); and (c) an orally acceptable carrier. In one embodiment, the carrier comprises a film forming material. Methods are also provided for making an oral care composition comprising: (a) mixing a whitening agent, silicone adhesive and carrier fluid to form a homogenous mixture; (b) adding a peroxide complex to said homogenous mixture, wherein said complex comprises hydrogen peroxide and an N-vinyl heterocyclic polymer; and (c) mixing under vacuum.
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公开(公告)号：US20080233058A1
公开(公告)日：2008-09-25
申请号：US12132359
申请日：2008-06-03
申请人： Prithwiraj Maitra , Lynette Zaidel , Suman K. Chopra , Guisheng Pan , Michael Prencipe , Syed Ibrahim
发明人： Prithwiraj Maitra , Lynette Zaidel , Suman K. Chopra , Guisheng Pan , Michael Prencipe , Syed Ibrahim
CPC分类号： A61K8/0208 , A61K8/22 , A61K8/8152 , A61K8/8176 , A61Q11/00
摘要： Oral care compositions comprising: a) an oral care active; and b) an acrylic film forming polymer. In various embodiments, such polymers comprise monomeric units such as acrylic acid, methacrylic acid, acrylates, and combinations thereof. In one embodiment, the film forming polymer comprises a copolymer of a first monomeric unit selected from the group consisting of acrylic acid, methacrylic acid, and combinations thereof, with a second monomeric unit selected from the group consisting of acrylates, acrylamides, acetates, and combinations thereof. In various embodiments, the polymer is a terpolymer comprising a combination of the second monomeric units. Preferably, the composition additionally comprises a lower alcohol, such as ethanol. In various embodiments, the oral care active comprises a whitening material, such as a peroxide.
摘要翻译： 口腔护理组合物，其包含：a）口腔护理活性物质; 和b）丙烯酸成膜聚合物。 在各种实施方案中，这种聚合物包含单体单元，例如丙烯酸，甲基丙烯酸，丙烯酸酯及其组合。 在一个实施方案中，成膜聚合物包含选自丙烯酸，甲基丙烯酸及其组合的第一单体单元与第二单体单元的共聚物，所述第二单体单元选自丙烯酸酯，丙烯酰胺，乙酸酯和 其组合。 在各种实施方案中，聚合物是包含第二单体单元的组合的三元共聚物。 优选地，组合物另外包含低级醇，例如乙醇。 在各种实施方案中，口腔护理活性物质包含增白材料，例如过氧化物。
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公开(公告)号：US10092482B2
公开(公告)日：2018-10-09
申请号：US12132359
申请日：2008-06-03
申请人： Prithwiraj Maitra , Lynette Zaidel , Suman K. Chopra , Guisheng Pan , Michael Prencipe , Sayed Ibrahim
发明人： Prithwiraj Maitra , Lynette Zaidel , Suman K. Chopra , Guisheng Pan , Michael Prencipe , Sayed Ibrahim
摘要： Oral care compositions comprising: a) an oral care active; and b) an acrylic film forming polymer. In various embodiments, such polymers comprise monomeric units such as acrylic acid, methacrylic acid, acrylates, and combinations thereof. In one embodiment, the film forming polymer comprises a copolymer of a first monomeric unit selected from the group consisting of acrylic acid, methacrylic acid, and combinations thereof, with a second monomeric unit selected from the group consisting of acrylates, acrylamides, acetates, and combinations thereof. In various embodiments, the polymer is a terpolymer comprising a combination of the second monomeric units. Preferably, the composition additionally comprises a lower alcohol, such as ethanol. In various embodiments, the oral care active comprises a whitening material, such as a peroxide.
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公开(公告)号：US09308399B2
公开(公告)日：2016-04-12
申请号：US13582115
申请日：2010-03-11
IPC分类号： A61Q11/00 , A61K8/22 , A61K8/25 , A61K6/00 , A61K33/40 , A61Q11/02 , A61K8/31 , A61K8/49 , A61K8/81 , A61K8/891
CPC分类号： A61Q11/00 , A61K8/22 , A61K8/31 , A61K8/4913 , A61K8/8111 , A61K8/8176 , A61K8/891
摘要： A tooth whitening composition for whitening a surface of a tooth, the composition comprising a mixture of a whitening agent comprising an aqueous peroxide, a hydrophobic polymer carrier for adhering the tooth whitening composition to a tooth surface and at least one adhesion enhancing agent.
摘要翻译： 一种用于使牙齿表面美白的牙齿美白组合物，所述组合物包含含有过氧化氢的增白剂，用于将牙齿增白组合物粘附到牙齿表面的疏水聚合物载体和至少一种粘合增强剂的混合物。
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公开(公告)号：US20120328535A1
公开(公告)日：2012-12-27
申请号：US13582115
申请日：2010-03-11
CPC分类号： A61Q11/00 , A61K8/22 , A61K8/31 , A61K8/4913 , A61K8/8111 , A61K8/8176 , A61K8/891
摘要： A tooth whitening composition for whitening a surface of a tooth, the composition comprising a mixture of a whitening agent comprising an aqueous peroxide, a hydrophobic polymer carrier for adhering the tooth whitening composition to a tooth surface and at least one adhesion enhancing agent.
摘要翻译： 一种用于使牙齿表面美白的牙齿美白组合物，所述组合物包含含有过氧化氢的增白剂，用于将牙齿增白组合物粘附到牙齿表面的疏水聚合物载体和至少一种粘合增强剂的混合物。
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10.发明申请DUAL ACTION DENTIFRICE COMPOSITIONS TO PREVENT HYPERSENSITIVITY AND PROMOTE REMINERALIZATION 审中-公开双重作用DENTIFRICE组合物，以防止高度敏感性和促进重新定位公开(公告)号：US20120021031A1
公开(公告)日：2012-01-26
申请号：US13262010
申请日：2010-04-01
CPC分类号： A61Q11/00 , A61K8/19 , A61K8/20 , A61K8/25 , A61K2800/412
摘要： The invention encompasses combinations of bioactive glass composition and potassium salts that are useful in conjunction with delivery agent such as, for example, toothpastes, mouthwashes, and oral gels. In certain embodiments, the compositions of the invention form a rapid and continuous reaction with body fluids (e.g., saliva) to promote the immediate and long-tem release of Ca and P ions to produce a stable crystalline layer deposited onto and into the dentin tubules for the immediate and long term reduction of dentin hypersensitivity and tooth surface remineralization.
摘要翻译： 本发明包括与递送剂例如牙膏，漱口剂和口服凝胶一起使用的生物活性玻璃组合物和钾盐的组合。 在某些实施方案中，本发明的组合物与体液（例如唾液）形成快速且连续的反应，以促进Ca和P离子的即时和长期释放，以产生沉积在牙质小管上和之上的稳定的晶体层 用于立即和长期减少牙质过敏和牙齿表面再矿化。
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