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1.发明申请NOVEL FORMULATIONS OF FAT-SOLUBLE ACTIVE INGREDIENTS WITH HIGH BIOAVAILABILITY 审中-公开具有高生物利用性的脂溶性活性成分的新配方公开(公告)号：US20120039964A1
公开(公告)日：2012-02-16
申请号：US13282708
申请日：2011-10-27
申请人： Markus BECK , Hansjoerg Grass , Bruno H. Leuenberger , Markus Nowotny , Christian Schäfer , Karl Manfred Voelker
发明人： Markus BECK , Hansjoerg Grass , Bruno H. Leuenberger , Markus Nowotny , Christian Schäfer , Karl Manfred Voelker
IPC分类号： A61K9/107 , A61K31/573 , A61P3/02 , A61K31/12 , A61K31/11 , A61K31/015 , A61K31/01
CPC分类号： A61K9/2081 , A23K20/174 , A23K20/179 , A23L5/44 , A23L33/155 , A23V2002/00 , A61K8/0241 , A61K8/31 , A61K9/2013 , A61K9/2018 , A61K9/2059 , A61K31/01 , A61K31/047 , A61K2800/52 , A61K2800/56 , A61Q19/00
摘要： The present invention relates to formulations of a pharmacological effective fat-soluble active ingredient with a high bioavailability of said fat-soluble active ingredient as well as to their manufacture and use as dietary supplement, food, feed, personal care product and/or pharmaceutical. Such formulations are those which when dissolved, dispersed or diluted in/with water have an extinction E1/1 at a wavelength in the range of from 200 to 800 nm, preferably in the range of from 250 to 600 nm, more preferably in the range of from 250 to 500 nm, more preferably in the range of from 370 to 485 nm, of ≧380, preferably of ≧600, most preferably ≧900. In preferred embodiments of the formulations of the present invention such formulations show an extrusion loss of fat-soluble active ingredient of ≦30% when pressed to tablets.
摘要翻译： 本发明涉及具有所述脂溶性活性成分的高生物利用度的药理学有效的脂溶性活性成分以及作为膳食补充剂，食品，饲料，个人护理产品和/或药物的制造和用途的制剂。 这样的配方是当在水中溶解，分散或稀释时在200至800nm范围内，优选在250至600nm范围内的波长具有消光E1 / 1，更优选在该范围内 250〜500nm，更优选370〜485nm，≥380，优选≥600，最优选≥900。 在本发明制剂的优选实施方案中，这些制剂显示当压制成片剂时，脂溶性活性成分的挤出损失为30％。
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2.发明申请Novel Formulations of Fat-Soluble Active Ingredients with High Biovailability 审中-公开具有高生物利用度的脂溶性活性成分的新型配方公开(公告)号：US20080299209A1
公开(公告)日：2008-12-04
申请号：US12064886
申请日：2006-10-20
申请人： Markus Beck , Hansjoerg Grass , Bruno Leuenberger , Markus Nowotny , Christian Schafer , Karl Manfred Voelker
发明人： Markus Beck , Hansjoerg Grass , Bruno Leuenberger , Markus Nowotny , Christian Schafer , Karl Manfred Voelker
IPC分类号： A61K9/14 , A61K31/01 , A61K31/015 , A61K31/047 , A61K31/122 , A61K31/215 , A23L1/29
CPC分类号： A61K9/2081 , A23K20/174 , A23K20/179 , A23L5/44 , A23L33/155 , A23V2002/00 , A61K8/0241 , A61K8/31 , A61K9/2013 , A61K9/2018 , A61K9/2059 , A61K31/01 , A61K31/047 , A61K2800/52 , A61K2800/56 , A61Q19/00
摘要： The present invention relates to formulations of a pharmacological effective fat-soluble active ingredient with a high bioavailability of said fat-soluble active ingredient as well as to their manufacture and use as dietary supplement, food, feed, personal care product and/or pharmaceutical. Such formulations are those which when dissolved, dispersed or diluted in/with water have an extinction E 1/1 at a wavelength in the range of from 200 to 800 nm, preferably in the range of from 250 to 600 nm, more preferably in the range of from 250 to 500 nm, more preferably in the range of from 370 to 485 nm, of ≧380, preferably of ≧600, most preferably ≧900. In preferred embodiments of the formulations of the present invention such formulations show an extrusion loss of fat-soluble active ingredient of ≦30% when pressed to tablets.
摘要翻译： 本发明涉及具有所述脂溶性活性成分的高生物利用度的药理学有效的脂溶性活性成分以及作为膳食补充剂，食品，饲料，个人护理产品和/或药物的制造和用途的制剂。 这种制剂是当在水中溶解，分散或稀释时在200至800nm范围内，优选在250至600nm范围内的波长具有消光E 1/1，更优选在 范围为250至500nm，更优选为370至485nm，≥380，优选> = 600，最优选> = 900。 在本发明制剂的优选实施方案中，这些制剂显示当压制成片剂时，脂溶性活性成分的挤出损失<= 30％。
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公开(公告)号：US20100136177A1
公开(公告)日：2010-06-03
申请号：US12526148
申请日：2008-02-04
IPC分类号： A23L1/275 , A23L1/303 , A23L1/0522 , A23L1/0524 , A23L1/053 , A23L1/0534
CPC分类号： A23L2/58 , A23L2/395 , A23L33/105 , A23L33/155 , A23P10/40 , A23V2002/00 , A23V2200/30 , A23V2250/211 , A23V2250/5118 , A23V2250/5114 , A23V2200/254
摘要： Process for the manufacture of a powder containing one or more carotenoids, powder obtainable by said process and food composition containing said powder.
摘要翻译： 用于制造含有一种或多种类胡萝卜素的粉末的方法，所述方法可获得的粉末和含有所述粉末的食品组合物。
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公开(公告)号：US10362800B2
公开(公告)日：2019-07-30
申请号：US13976696
申请日：2011-12-27
申请人： Martin Gadient , Thomas Lindemann , Mischa Schwaninger , Karl Manfred Voelker , Kai Urban , Stefanie Kirchen
发明人： Martin Gadient , Thomas Lindemann , Mischa Schwaninger , Karl Manfred Voelker , Kai Urban , Stefanie Kirchen
IPC分类号： A23L1/302 , A61K8/02 , A61K8/67 , A23P10/43 , A61K9/14 , A61K9/16 , A61K31/335 , A61K8/25 , A61Q19/00 , A23K40/10 , A23K20/174 , A23L33/15
摘要： The present invention relates to improved vitamin E formulations, as well as to the production of such formulations.
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公开(公告)号：US20080193539A1
公开(公告)日：2008-08-14
申请号：US11995619
申请日：2006-07-06
申请人： Karl Manfred Voelker
发明人： Karl Manfred Voelker
CPC分类号： A61K47/06 , A23K20/174 , A23K20/179 , A23L5/44 , A23L29/212 , A23L29/25 , A23L29/35 , A23L33/155 , A23V2002/00 , A61K8/31 , A61K8/732 , A61K31/015 , A61K2800/43 , A61K2800/522 , A61Q19/00 , C09B61/00 , C09B67/0089 , A23V2250/211 , A23V2250/5118 , A23V2250/5114 , A23V2250/5028
摘要： The present invention relates to novel compositions containing finely dispersed carotenoids. The novel compositions of this invention can be used as colorants or additives for food, beverages, animal feeds, cosmetics or drugs. The colorant composition may be a liquid or a solid composition. The solid composition comprises at least one carotenoid which is dispersed in a matrix, wherein the matrix contains at least one carbohydrate and/or one modified carbohydrate and optionally, a protein, a modified protein or mixtures thereof, wherein the at least one carbohydrate and/or one modified carbohydrate is starch or modified starch, wherein the amount of starch or modified starch is from about 10 wt-% to 60 wt-% of based on the total weight of the matrix, and wherein the concentration of the at least one carotenoid is at least 2% based on the total weight of the composition. Preferably β-carotene is used as a solid water-dispersible colorant composition.
摘要翻译： 本发明涉及含有微细分散的类胡萝卜素的新型组合物。 本发明的新型组合物可用作食品，饮料，动物饲料，化妆品或药物的着色剂或添加剂。 着色剂组合物可以是液体或固体组合物。 固体组合物包含分散在基质中的至少一种类胡萝卜素，其中所述基质含有至少一种碳水化合物和/或一种修饰的碳水化合物和任选的蛋白质，修饰的蛋白质或其混合物，其中所述至少一种碳水化合物和/ 或一种修饰的碳水化合物是淀粉或改性淀粉，其中基于所述基质的总重量，淀粉或改性淀粉的量为约10重量％至60重量％，并且其中所述至少一种类胡萝卜素 基于组合物的总重量至少为2％。 优选β-胡萝卜素用作固体水分散性着色剂组合物。
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公开(公告)号：US08912237B2
公开(公告)日：2014-12-16
申请号：US13941428
申请日：2013-07-12
申请人： Karl Manfred Voelker
发明人： Karl Manfred Voelker
IPC分类号： A01N47/00 , A23L1/09 , A23L1/303 , A23L1/0522 , A23K1/16 , A61Q19/00 , C09B61/00 , A61K8/31 , A61K31/015 , A61K47/06 , C09B67/46 , A23L1/053 , A61K8/73 , A23L1/275
CPC分类号： A23L1/2753 , A23K20/174 , A23K20/179 , A23L5/44 , A23L29/212 , A23L29/25 , A23L29/35 , A23L33/155 , A23V2002/00 , A61K8/31 , A61K8/732 , A61K31/015 , A61K47/06 , A61K2800/43 , A61K2800/522 , A61Q19/00 , C09B61/00 , C09B67/0089 , A23V2250/211 , A23V2250/5118 , A23V2250/5114 , A23V2250/5028
摘要： The present invention relates to novel compositions containing finely dispersed carotenoids. The novel compositions of this invention can be used as colorants or additives for food, beverages, animal feeds, cosmetics or drugs. The colorant composition may be a liquid or a solid composition. The solid composition comprises at least one carotenoid which is dispersed in a matrix, wherein the matrix contains at least one carbohydrate and/or one modified carbohydrate and optionally, a protein, a modified protein or mixtures thereof, wherein the at least one carbohydrate and/or one modified carbohydrate is starch or modified starch, wherein the amount of starch or modified starch is from about 10 wt-% to 60 wt-% of based on the total weight of the matrix, and wherein the concentration of the at least one carotenoid is at least 2% based on the total weight of the composition. Preferably β-carotene is used as a solid water-dispersible colorant composition.
摘要翻译： 本发明涉及含有微细分散的类胡萝卜素的新型组合物。 本发明的新型组合物可用作食品，饮料，动物饲料，化妆品或药物的着色剂或添加剂。 着色剂组合物可以是液体或固体组合物。 固体组合物包含分散在基质中的至少一种类胡萝卜素，其中所述基质含有至少一种碳水化合物和/或一种修饰的碳水化合物和任选的蛋白质，修饰的蛋白质或其混合物，其中所述至少一种碳水化合物和/ 或一种修饰的碳水化合物是淀粉或改性淀粉，其中基于所述基质的总重量，淀粉或改性淀粉的量为约10重量％至60重量％，并且其中所述至少一种类胡萝卜素 基于组合物的总重量至少为2％。 优选地，β-胡萝卜素用作固体水分散着色剂组合物。
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公开(公告)号：US20100272861A1
公开(公告)日：2010-10-28
申请号：US12746238
申请日：2008-12-04
CPC分类号： A23L2/02 , A23L29/10 , A23L29/219 , A23L33/155 , A23P10/40
摘要： (Finely divided) pulverous formulation of one or more fat-soluble active ingredients comprising modified food starch and one or more components chosen from the group consisting of sorbitan monoesters of fatty acids with a chain length of 12 to 16 C atoms and food composition, especially a beverage, containing said formulation.
摘要翻译： 一种或多种脂溶性活性成分（细分）的粉末制剂，其包含改性食品淀粉和一种或多种选自下组的成分，所述组分选自链长为12至16 C原子的脂肪酸的脱水山梨糖醇单酯和食品组合物，特别是 含有所述制剂的饮料。
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公开(公告)号：US09445621B2
公开(公告)日：2016-09-20
申请号：US13390943
申请日：2010-09-03
CPC分类号： A23L2/02 , A23L2/52 , A23L2/68 , A23L33/12 , A23V2002/00 , C11B5/00 , C11B5/0021 , A23V2200/16 , A23V2250/1882 , A23V2250/211
摘要： The present invention relates to (fruit) juices and nectars formulations, comprising (LC)-PUFA's, which do not have the characteristic fish taste of the (long chain) polyunsaturated fatty acids. Furthermore, the present invention also relates to a base material, which comprises PUFA and β-carotene and the use of such a base material to produce a (fruit) juice or (fruit) nectar formulation.
摘要翻译： 本发明涉及（水果）果汁和花蜜制剂，其包含（LC）-PUFA，其不具有（长链）多不饱和脂肪酸的特征性鱼味。 此外，本发明还涉及包含PUFA和β-胡萝卜素的基材，以及使用这种基材来生产（果实）果汁或（水果）花蜜制剂。
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公开(公告)号：US20140056955A1
公开(公告)日：2014-02-27
申请号：US13976696
申请日：2011-12-27
申请人： Martin Gadient , Thomas Lindemann , Mischa Schwaninger , Karl Manfred Voelker , Kai Urban , Stefanie Kirchen
发明人： Martin Gadient , Thomas Lindemann , Mischa Schwaninger , Karl Manfred Voelker , Kai Urban , Stefanie Kirchen
CPC分类号： A23P10/43 , A23K20/174 , A23K40/10 , A23L33/15 , A61K8/0241 , A61K8/25 , A61K8/678 , A61K9/143 , A61K9/1611 , A61K9/1676 , A61K31/335 , A61K2800/10 , A61K2800/412 , A61Q19/00
摘要： The present invention relates to improved vitamin E formulations, as well as to the production of such formulations.
摘要翻译： 本发明涉及改良的维生素E制剂，以及这些制剂的生产。
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公开(公告)号：US20130004641A1
公开(公告)日：2013-01-03
申请号：US13390943
申请日：2010-09-03
CPC分类号： A23L2/02 , A23L2/52 , A23L2/68 , A23L33/12 , A23V2002/00 , C11B5/00 , C11B5/0021 , A23V2200/16 , A23V2250/1882 , A23V2250/211
摘要： The present invention relates to (fruit) juices and nectars formulations, comprising (LC)-PUFA's, which do not have the characteristic fish taste of the (long chain) polyunsaturated fatty acids. Furthermore, the present invention also relates to a base material, which comprises PUFA and β-carotene and the use of such a base material to produce a (fruit) juice or (fruit) nectar formulation.
摘要翻译： 本发明涉及（水果）果汁和花蜜制剂，其包含（LC）-PUFA，其不具有（长链）多不饱和脂肪酸的特征性鱼味。 此外，本发明还涉及一种基础材料，其包含PUFA和β-胡萝卜素，以及使用这种基料来生产（果实）果汁或（水果）花蜜制剂。
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