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公开(公告)号:US20110171259A1
公开(公告)日:2011-07-14
申请号:US13061841
申请日:2009-09-04
申请人: Martin Gagne , Daniel Larocque , Martin Plante
发明人: Martin Gagne , Daniel Larocque , Martin Plante
IPC分类号: A61K39/21 , C07K14/22 , A61K39/095 , A61K39/145 , A61P37/04 , A61P35/00 , A61P31/06 , A61P31/16 , A61P31/04 , A61P33/06 , A61P31/18 , A61P37/08 , C07K7/08
CPC分类号: A61K39/39 , A61K39/095 , A61K39/12 , A61K39/145 , A61K2039/543 , A61K2039/55516 , A61K2039/55572 , A61K2039/6018 , A61K2039/6068 , C12N2760/16134 , Y02A50/412
摘要: The present invention is directed toward adjuvants that effect an innate and/or a specific immune response. The adjuvants contain at least one lipoprotein, such as Lip, Lip fragments or Lip variants, where the lipoprotein comprises at least one pentameric unit and at least one lipid moiety. Adjuvants wherein the lipoprotein make up at least 10% of the adjuvant by weight/volume are provided.
摘要翻译: 本发明涉及影响先天和/或特异性免疫应答的佐剂。 佐剂含有至少一种脂蛋白,例如Lip,Lip片段或Lip变体,其中脂蛋白包含至少一个五聚体单元和至少一个脂质部分。 提供其中脂蛋白占重量/体积至少10%的佐剂的佐剂。
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公开(公告)号:US20140242112A1
公开(公告)日:2014-08-28
申请号:US14261938
申请日:2014-04-25
IPC分类号: A61K39/145 , A61K39/39 , A61K31/675
CPC分类号: A61K39/145 , A61K31/675 , A61K39/12 , A61K39/39 , A61K2039/542 , A61K2039/55511 , A61K2039/55516 , A61K2039/55544 , A61K2039/55561 , A61K2039/55572 , A61K2039/55594 , C12N2760/16134
摘要: The present invention provides an immunogenic composition comprising one or more antigens and a Toll-like receptor (TLR) 7 agonist in an orally (e.g. sublingually) administered composition.
摘要翻译: 本发明提供在口服(例如舌下)给药组合物中包含一种或多种抗原和Toll样受体(TLR)7激动剂的免疫原性组合物。
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3.
公开(公告)号:US20130089570A1
公开(公告)日:2013-04-11
申请号:US13701237
申请日:2011-02-06
IPC分类号: A61K39/39
CPC分类号: A61K39/39 , A61K39/12 , A61K39/145 , A61K2039/542 , A61K2039/55511 , A61K2039/55516 , A61K2039/55594 , C12N2760/16134
摘要: The present invention provides an immunogenic composition comprising one or more antigens and a Toll-like receptor (TLR) agonist in an orally (e.g. sublingually) administered composition.
摘要翻译: 本发明提供在口服(例如舌下)施用的组合物中包含一种或多种抗原和Toll样受体(TLR)激动剂的免疫原性组合物。
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公开(公告)号:US20120117730A1
公开(公告)日:2012-05-17
申请号:US13296656
申请日:2011-11-15
申请人: Guy Lemire , Martin W. Stryker , Pascal Castonguay , Clifford Edwin Lambarth , Chad Conway Souke , Kurosh Nahavandi , Adam Darwin Downey , Robert Gregory Cox , Michael Joseph Hayes , Aaron Douglas Furman , Martin Plante
发明人: Guy Lemire , Martin W. Stryker , Pascal Castonguay , Clifford Edwin Lambarth , Chad Conway Souke , Kurosh Nahavandi , Adam Darwin Downey , Robert Gregory Cox , Michael Joseph Hayes , Aaron Douglas Furman , Martin Plante
CPC分类号: A61G7/05 , A61G1/0268 , A61G1/04 , A61G3/0236 , A61G3/0254 , A61G3/0272 , A61G3/029 , A61G3/0875 , A61G5/10 , A61G7/005 , A61G7/012 , A61G7/015 , A61G7/018 , A61G7/0506 , A61G7/1042 , A61G7/1046 , A61G7/1067 , A61G7/1076 , A61G2200/32 , A61G2200/325 , A61G2200/34 , A61G2203/10 , A61G2203/42 , A61G2205/60 , H02J5/005 , H02J7/025 , H02J50/12 , H02J50/90
摘要: A patient support apparatus, such as a bed, cot, stretcher, gurney, surgical table, or the like, is disclosed that includes at least one form of wireless energy transfer and/or at least one form of wireless communication amongst its components. The wireless energy transfer may include the inductive transfer of electrical energy from the main body of the patient support apparatus to a mattress positioned thereon that uses electrical energy. Alternatively, the wireless energy transfer may include the inductive transfer or electrical energy from a stationary power station to the patient support itself. Or, the patient support apparatus may include both types of inductive energy transfer. The wireless communication may be between a controller on the main body of the patient support apparatus and a controller within, or coupled to, the mattress.
摘要翻译: 公开了一种患者支持装置,例如床,婴儿床,担架,轮辋,外科手术台等,其包括至少一种形式的无线能量传递和/或其组件中的至少一种形式的无线通信。 无线能量传递可以包括将电能从患者支撑装置的主体感应转移到使用电能的位于其上的床垫。 或者,无线能量传递可以包括从固定电站到患者支架本身的感应转移或电能。 或者,患者支持装置可以包括两种类型的感应能量传递。 无线通信可以在患者支持装置的主体上的控制器与床垫之间或耦合到床垫之间的控制器之间。
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公开(公告)号:US06743900B2
公开(公告)日:2004-06-01
申请号:US09788280
申请日:2001-02-15
申请人: David S. Burt , David Hugh Jones , George H. Lowell , Gregory Lee White , Kirkor Torossian , Louis F. Fries, III , Martin Plante
发明人: David S. Burt , David Hugh Jones , George H. Lowell , Gregory Lee White , Kirkor Torossian , Louis F. Fries, III , Martin Plante
IPC分类号: A23J100
CPC分类号: A61K39/39 , A61K39/12 , A61K39/145 , A61K2039/5252 , A61K2039/543 , A61K2039/55516 , A61K2039/55555 , A61K2039/70 , C12N2760/16134 , C12N2760/16234
摘要: Improved forms of vaccines which comprise proteosomes and protein antigens are described. Vaccines which contain influenza HA as the antigen are used for illustration as to demonstrate efficacy. Improvements in the preparation of the vaccines themselves and the proteosome component are also included.
摘要翻译: 描述了包含蛋白质体和蛋白质抗原的改进形式的疫苗。 含有流感HA作为抗原的疫苗用于说明以证明疗效。 还包括疫苗本身和蛋白质组分的制备的改进。
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公开(公告)号:US08544126B2
公开(公告)日:2013-10-01
申请号:US13034303
申请日:2011-02-24
申请人: Derick Elliott , David Mayen Moreno , Martin Plante , Chad Rohrer , David Kim Soui Wan Fong , Annie Désaulniers
发明人: Derick Elliott , David Mayen Moreno , Martin Plante , Chad Rohrer , David Kim Soui Wan Fong , Annie Désaulniers
CPC分类号: A61G7/018 , A61B5/103 , A61B5/11 , A61B5/447 , A61B5/6892 , A61B5/743 , A61B5/7435 , A61G7/005 , A61G7/012 , A61G7/015 , A61G7/0506 , A61G7/0507 , A61G7/0509 , A61G7/0514 , A61G7/0524 , A61G7/0527 , A61G7/0528 , A61G7/08 , A61G2203/16 , A61G2203/20 , A61G2203/32 , A61G2203/42 , A61G2210/50 , G01G19/44 , G01G19/52 , G01G23/32 , G01G23/42 , G06F3/04817 , G06F3/04842 , G06F3/0488 , G06F19/00 , G16H40/20 , G16H40/63
摘要: A patient support apparatus includes a frame, a patient support surface supported in the frame, and a plurality of functional components associated with the patient support surface or the frame. The apparatus further includes a control system, with a controller, incorporated into the patient support surface or the frame and in operative communication with at least one of the functional components for controlling the component. The control system further includes a touch-screen in communication with the controller for controlling the functional component, which is positioned in the barrier around the patient support surface, and accessible at the exterior or interior surface of the barrier for access by a user. The touch-screen is configured to allow the user to select one or more of the functional components and control a parameter associated with the selected functional component. In addition, an icon is generated at the touch-screen representative of the parameter associated with the selected functional component, and with icon changing in response to the user adjusting the parameter associated with the selected functional component wherein the change in the icon gives the user feedback on the degree of change made by the user to the parameter associated with the selected functional component.
摘要翻译: 患者支撑装置包括框架,支撑在框架中的患者支撑表面以及与患者支撑表面或框架相关联的多个功能部件。 该装置还包括具有控制器的控制系统,其结合到患者支撑表面或框架中并且与用于控制部件的至少一个功能组件可操作地通信。 控制系统还包括与控制器通信的触摸屏,用于控制功能部件,该功能部件位于患者支撑表面周围的障碍物中,并且在屏障的外表面或内表面可访问以供用户访问。 触摸屏被配置为允许用户选择一个或多个功能组件并且控制与所选择的功能组件相关联的参数。 此外,在代表与所选择的功能组件相关联的参数的触摸屏上生成图标,并且响应于用户调整与所选择的功能组件相关联的参数而改变图标,其中图标的改变给予用户 关于用户对与所选择的功能组件相关联的参数的改变程度的反馈。
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公开(公告)号:US09038217B2
公开(公告)日:2015-05-26
申请号:US11941338
申请日:2007-11-16
申请人: Derick Elliot , David Mayen Moreno , Martin Plante , Chad Rohrer , David Kim Soui Wan Fong , Annie Désaulniers
发明人: Derick Elliot , David Mayen Moreno , Martin Plante , Chad Rohrer , David Kim Soui Wan Fong , Annie Désaulniers
IPC分类号: A61G7/05 , A61B5/00 , A61G7/005 , A61G7/012 , A61G7/015 , A61G7/018 , G06F19/00 , A61B5/103 , A61B5/11 , A61G7/08
CPC分类号: A61G7/018 , A61B5/103 , A61B5/11 , A61B5/447 , A61B5/6892 , A61B5/743 , A61B5/7435 , A61G7/005 , A61G7/012 , A61G7/015 , A61G7/0506 , A61G7/0507 , A61G7/0509 , A61G7/0514 , A61G7/0524 , A61G7/0527 , A61G7/0528 , A61G7/08 , A61G2203/16 , A61G2203/20 , A61G2203/32 , A61G2203/42 , A61G2210/50 , G01G19/44 , G01G19/52 , G01G23/32 , G01G23/42 , G06F3/04817 , G06F3/04842 , G06F3/0488 , G06F19/00 , G16H40/20 , G16H40/63
摘要: A patient support includes a frame, a patient support surface supported at the frame, a display incorporated into the frame, and a user interface incorporated into the frame. The patient support frame includes a controller incorporated into the frame, which has a plurality of prompts stored therein. The user interface is in communication with the controller and may be used to select a selected prompt from the plurality of prompts stored in the controller. When a prompt is selected, the controller generates a display image or text associated with the selected prompt at the display in response to a passage of time or an input to provide a visual prompt to the user.
摘要翻译: 患者支架包括框架,支撑在框架处的患者支撑表面,结合到框架中的显示器以及结合到框架中的用户界面。 患者支撑框架包括结合到框架中的控制器,其中存储有多个提示。 用户界面与控制器通信,并且可以用于从存储在控制器中的多个提示中选择所选择的提示。 当选择了提示时,控制器响应于时间的流逝或输入,在显示器上产生与所选提示相关联的显示图像或文本,以向用户提供视觉提示。
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公开(公告)号:US20110144548A1
公开(公告)日:2011-06-16
申请号:US13034303
申请日:2011-02-24
申请人: Derick Elliott , David Mayen Moreno , Martin Plante , Chad Rohrer , David Kim Soui Wan Fong , Annie Désaulniers
发明人: Derick Elliott , David Mayen Moreno , Martin Plante , Chad Rohrer , David Kim Soui Wan Fong , Annie Désaulniers
CPC分类号: A61G7/018 , A61B5/103 , A61B5/11 , A61B5/447 , A61B5/6892 , A61B5/743 , A61B5/7435 , A61G7/005 , A61G7/012 , A61G7/015 , A61G7/0506 , A61G7/0507 , A61G7/0509 , A61G7/0514 , A61G7/0524 , A61G7/0527 , A61G7/0528 , A61G7/08 , A61G2203/16 , A61G2203/20 , A61G2203/32 , A61G2203/42 , A61G2210/50 , G01G19/44 , G01G19/52 , G01G23/32 , G01G23/42 , G06F3/04817 , G06F3/04842 , G06F3/0488 , G06F19/00 , G16H40/20 , G16H40/63
摘要: A patient support apparatus includes a frame, a patient support surface supported in the frame, and a plurality of functional components associated with the patient support surface or the frame. The apparatus further includes a control system, with a controller, incorporated into the patient support surface or the frame and in operative communication with at least one of the functional components for controlling the component. The control system further includes a touch-screen in communication with the controller for controlling the functional component, which is positioned in the barrier around the patient support surface, and accessible at the exterior or interior surface of the barrier for access by a user. The touch-screen is configured to allow the user to select one or more of the functional components and control a parameter associated with the selected functional component. In addition, an icon is generated at the touch-screen representative of the parameter associated with the selected functional component, and with icon changing in response to the user adjusting the parameter associated with the selected functional component wherein the change in the icon gives the user feedback on the degree of change made by the user to the parameter associated with the selected functional component.
摘要翻译: 患者支撑装置包括框架,支撑在框架中的患者支撑表面以及与患者支撑表面或框架相关联的多个功能部件。 该装置还包括具有控制器的控制系统,其结合到患者支撑表面或框架中并且与用于控制部件的至少一个功能组件可操作地通信。 控制系统还包括与控制器通信的触摸屏,用于控制功能部件,该功能部件位于患者支撑表面周围的障碍物中,并且在屏障的外表面或内表面可访问以供用户访问。 触摸屏被配置为允许用户选择一个或多个功能组件并且控制与所选择的功能组件相关联的参数。 此外,在代表与所选择的功能组件相关联的参数的触摸屏上生成图标,并且响应于用户调整与所选择的功能组件相关联的参数而改变图标,其中图标的改变给予用户 关于用户对与所选择的功能组件相关联的参数的改变程度的反馈。
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公开(公告)号:US07399840B2
公开(公告)日:2008-07-15
申请号:US10771737
申请日:2004-02-03
申请人: David S. Burt , David H. Jones , George H. Lowell , Gregory L. White , Kirkor Torossian , Louis F. Fries, III , Martin Plante
发明人: David S. Burt , David H. Jones , George H. Lowell , Gregory L. White , Kirkor Torossian , Louis F. Fries, III , Martin Plante
IPC分类号: A23J1/00
CPC分类号: A61K39/39 , A61K39/12 , A61K39/145 , A61K2039/5252 , A61K2039/543 , A61K2039/55516 , A61K2039/55555 , A61K2039/70 , C12N2760/16134 , C12N2760/16234
摘要: Improved forms of vaccines which comprise proteosomes and protein antigens are described. Vaccines which contain influenza HA as the antigen are used for illustration as to demonstrate efficacy. Improvements in the preparation of the vaccines themselves and the proteosome component are also included.
摘要翻译: 描述了包含蛋白质体和蛋白质抗原的改进形式的疫苗。 含有流感HA作为抗原的疫苗用于说明以证明疗效。 还包括疫苗本身和蛋白质组分的制备的改进。
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公开(公告)号:US08864205B2
公开(公告)日:2014-10-21
申请号:US13296656
申请日:2011-11-15
申请人: Guy Lemire , Martin W. Stryker , Pascal Castonguay , Clifford Edwin Lambarth , Chad Conway Souke , Kurosh Nahavandi , Adam Darwin Downey , Robert Gregory Cox , Michael Joseph Hayes , Aaron Douglas Furman , Martin Plante
发明人: Guy Lemire , Martin W. Stryker , Pascal Castonguay , Clifford Edwin Lambarth , Chad Conway Souke , Kurosh Nahavandi , Adam Darwin Downey , Robert Gregory Cox , Michael Joseph Hayes , Aaron Douglas Furman , Martin Plante
IPC分类号: A61G1/02 , A61G7/05 , A61G7/005 , A61G3/02 , A61G7/018 , A61G7/012 , A61G1/04 , A61G7/015 , A61G7/10 , H02J5/00
CPC分类号: A61G7/05 , A61G1/0268 , A61G1/04 , A61G3/0236 , A61G3/0254 , A61G3/0272 , A61G3/029 , A61G3/0875 , A61G5/10 , A61G7/005 , A61G7/012 , A61G7/015 , A61G7/018 , A61G7/0506 , A61G7/1042 , A61G7/1046 , A61G7/1067 , A61G7/1076 , A61G2200/32 , A61G2200/325 , A61G2200/34 , A61G2203/10 , A61G2203/42 , A61G2205/60 , H02J5/005 , H02J7/025 , H02J50/12 , H02J50/90
摘要: A patient support apparatus, such as a bed, cot, stretcher, gurney, surgical table, or the like, is disclosed that includes at least one form of wireless energy transfer and/or at least one form of wireless communication amongst its components. The wireless energy transfer may include the inductive transfer of electrical energy from the main body of the patient support apparatus to a mattress positioned thereon that uses electrical energy. Alternatively, the wireless energy transfer may include the inductive transfer or electrical energy from a stationary power station to the patient support itself. Or, the patient support apparatus may include both types of inductive energy transfer. The wireless communication may be between a controller on the main body of the patient support apparatus and a controller within, or coupled to, the mattress.
摘要翻译: 公开了一种患者支持装置,例如床,婴儿床,担架,轮辋,外科手术台等,其包括至少一种形式的无线能量传递和/或其组件中的至少一种形式的无线通信。 无线能量传递可以包括将电能从患者支撑装置的主体感应转移到使用电能的位于其上的床垫。 或者,无线能量传递可以包括从固定电站到患者支架本身的感应转移或电能。 或者,患者支持装置可以包括两种类型的感应能量传递。 无线通信可以在患者支持装置的主体上的控制器与床垫之间或耦合到床垫之间的控制器之间。
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