Amorphous cefditoren pivoxil composition and process for producing the same
    1.
    发明授权
    Amorphous cefditoren pivoxil composition and process for producing the same 失效
    无定形头孢托仑匹酯组合物及其制备方法

    公开(公告)号:US07527808B2

    公开(公告)日:2009-05-05

    申请号:US10475729

    申请日:2002-04-26

    Applicant: Masato Ohta

    Inventor: Masato Ohta

    Abstract: An objective of the present invention is to provide an amorphous cefditoren pivoxil composition possessing excellent stability and dissolvability and to provide a production process of the amorphous composition. The amorphous cefditoren pivoxil composition according to the present invention comprises cefditoren pivoxil and a pharmaceutically acceptable organic polymeric compound, wherein the composition is obtainable by grinding a crystalline cefditoren pivoxil in the presence of a pharmaceutically acceptable organic polymeric compound to convert the crystalline cefditoren pivoxil to an amorphous substance.

    Abstract translation: 本发明的目的是提供具有优异稳定性和溶解性的无定形头孢托仑匹酯组合物,并提供无定形组合物的制备方法。 根据本发明的无定形头孢托仑匹酯组合物包含匹戊头孢托仑和药学上可接受的有机聚合化合物,其中所述组合物可通过在药学上可接受的有机高分子化合物存在下研磨结晶头孢托仑匹酯来获得,以将结晶头孢托仑匹酯转化为 无定形物质。

    METHODS FOR FORMING TOOTH ROOT AND PERIODONTAL TISSUE UNIT, AND REGENERATED TOOTH
    2.
    发明申请
    METHODS FOR FORMING TOOTH ROOT AND PERIODONTAL TISSUE UNIT, AND REGENERATED TOOTH 有权
    形成牙根和周围组织的方法和再生牙

    公开(公告)号:US20110212418A1

    公开(公告)日:2011-09-01

    申请号:US13040672

    申请日:2011-03-04

    CPC classification number: A61L27/3604 A61L27/3804 A61L27/3865

    Abstract: A method for forming at least a tooth root in a tooth containing a tooth crown, including: forming a culture core containing the tooth and a cell-containing base material, the tooth being wrapped with the cell-containing base material, and culturing the culture core in a medium to form at least the tooth root in the tooth contained therein, wherein the cell-containing base material contains at least one kind of cells selected from periodontal ligament-derived cells, bone marrow-derived cells, dental follicle-derived cells, dental pulp-derived cells and dental papilla-derived cells, and the medium contains a component contained in a conditioned medium of a serum-free-cultured cell line of a human uterocervical squamous carcinoma cell line; an additive containing at least one selected from IL-1β, IL-6, IL-8, IL-9, EGF, IGF-I, GH, PDGF-AB, VEGF, LIF, HGF, FGF-2, FGF-1, BMP-2, BMP-4, M-CSF, dexamethasone, insulin, thyroxine, thyrocalcitonin, ascorbic acid and β-glycerophosphate; or both of them.

    Abstract translation: 一种在含有牙冠的牙齿中至少形成齿根的方法,包括:形成含有牙齿的培养核和含细胞的基材,所述牙齿用含细胞的基材包裹,并培养培养物 在培养基中形成至少在其中含有的牙齿中的牙根,其中所述含细胞的基质材料含有选自牙周韧带衍生的细胞,骨髓来源的细胞,来自牙囊的细胞中的至少一种细胞 牙髓源细胞和来自乳头乳头的细胞,培养基含有人子宫颈鳞状细胞癌细胞系的无血清培养细胞系的条件培养基中所含的成分, 含有选自IL-1和bgr,IL-6,IL-8,IL-9,EGF,IGF-1,GH,PDGF-AB,VEGF,LIF,HGF,FGF-2,FGF-1中的至少一种的添加剂 ,BMP-2,BMP-4,M-CSF,地塞米松,胰岛素,甲状腺素,降钙素原,抗坏血酸和甘油磷酸酯; 或者他们两个。

    MOLD FOR FOAM MOLDING AND METHOD FOR PRODUCING FOAM-MOLDED MEMBER
    4.
    发明申请
    MOLD FOR FOAM MOLDING AND METHOD FOR PRODUCING FOAM-MOLDED MEMBER 有权
    用于泡沫模制的模具和用于生产泡沫塑料构件的方法

    公开(公告)号:US20120286445A1

    公开(公告)日:2012-11-15

    申请号:US13574130

    申请日:2011-01-27

    Applicant: Masato Ohta

    Inventor: Masato Ohta

    Abstract: Disclosed is a mold for foam molding capable of making the operation to attach a reinforcing member to an inner surface of a mold easier, capable of sufficiently preventing entry of foam synthetic resin between the reinforcing member and the inner surface of the mold at the time of foam-molding, and capable of preventing the reinforcing member from becoming wrinkled; and also provided is a method for producing a foam-molded member which has a reinforcing member using this mold for foam molding. A mold 20 for foam molding is used to foam-mold a seat pad 1 which is provided with a seat pad main body 2 and a reinforcing member 10 disposed on the back side of the seat pad main body 2. At the time of foam-molding, the reinforcing member 10 is disposed inside the mold 20 and an end edge of the reinforcing member 10 is secured to the inner surface of the mold 20 by a securing means. A tension application means is provided which applies tension to the end edge of the reinforcing member 10 in a direction to separate from the securing means.

    Abstract translation: 公开了一种用于发泡成型的模具,其能够更容易地将加强构件附接到模具的内表面,能够充分防止泡沫合成树脂在加强构件与模具的内表面之间进入时 发泡成型,能够防止加强部件起皱; 并且还提供了一种使用该模具进行发泡成型的具有加强构件的发泡成型构件的制造方法。 用于发泡成型的模具20用于对设置有座垫主体2和设置在座椅垫主体2的背侧的加强构件10的座垫1进行发泡模塑。 加强构件10设置在模具20的内部,并且加强构件10的端边缘通过固定装置固定到模具20的内表面。 提供张力施加装置,其在与固定装置分离的方向上向加强构件10的端部边缘施加张力。

    PHARMACEUTICAL PREPARATION FOR PREVENTING AND/OR TREATING PERIODONTAL DISEASE, AGENT FOR ORAL HYGIENE COMPRISING THEREOF, AND FOOD COMPRISING THEREOF
    5.
    发明申请
    PHARMACEUTICAL PREPARATION FOR PREVENTING AND/OR TREATING PERIODONTAL DISEASE, AGENT FOR ORAL HYGIENE COMPRISING THEREOF, AND FOOD COMPRISING THEREOF 审中-公开
    用于预防和/或治疗周围疾病的药物制剂,其包含口腔卫生的药剂及其包含的食品

    公开(公告)号:US20100130622A1

    公开(公告)日:2010-05-27

    申请号:US12275643

    申请日:2008-11-21

    CPC classification number: A61K31/05

    Abstract: The present invention provides a pharmaceutical composition for preventing and/or treating periodontal disease comprising at least one having dental root-periodontal tissue formation promotion effect selected from the group consisting of a compound shown in a following formula (I). (In the formula, R1 and R2 are independently functional groups selected from a group consisting of a substituted or non-substituted group of a linear alkyl group, a branched alkyl group, a linear alkenyl group and a branched alkenyl group with having the carbon number of 3 to 5. R′1 and R′2 are independently a hydrogen atom, hydroxyl group, or alkoxy group having the carbon number of 1 to 3.)

    Abstract translation: 本发明提供一种用于预防和/或治疗牙周病的药物组合物,其包含至少一种具有选自由下式(I)表示的化合物组成的组中的牙根牙周组织形成促进作用的药物组合物。 (式中,R 1和R 2分别独立地为选自具有碳数的直链烷基,支链烷基,直链烯基和支链烯基的取代或未取代的基团的官能团 R'1和R'2独立地为氢原子,羟基或碳数为1至3的烷氧基。)

    Methods for forming tooth root and periodontal tissue unit, and regenerated tooth
    7.
    发明授权
    Methods for forming tooth root and periodontal tissue unit, and regenerated tooth 有权
    形成牙根和牙周组织单位和再生牙齿的方法

    公开(公告)号:US08822212B2

    公开(公告)日:2014-09-02

    申请号:US13040672

    申请日:2011-03-04

    CPC classification number: A61L27/3604 A61L27/3804 A61L27/3865

    Abstract: A method for forming at least a tooth root in a tooth containing a tooth crown, including: forming a culture core containing the tooth and a cell-containing base material, the tooth being wrapped with the cell-containing base material, and culturing the culture core in a medium to form at least the tooth root in the tooth contained therein, wherein the cell-containing base material contains at least one kind of cells selected from periodontal ligament-derived cells, bone marrow-derived cells, dental follicle-derived cells, dental pulp-derived cells and dental papilla-derived cells, and the medium contains a component contained in a conditioned medium of a serum-free-cultured cell line of a human uterocervical squamous carcinoma cell line; an additive containing at least one selected from IL-1β, IL-6, IL-8, IL-9, EGF, IGF-I, GH, PDGF-AB, VEGF, LIF, HGF, FGF-2, FGF-1, BMP-2, BMP-4, M-CSF, dexamethasone, insulin, thyroxine, thyrocalcitonin, ascorbic acid and β-glycerophosphate; or both of them.

    Abstract translation: 一种在含有牙冠的牙齿中至少形成齿根的方法,包括:形成含有牙齿的培养核和含细胞的基材,所述牙齿用含细胞的基材包裹,并培养培养物 在培养基中形成至少在其中含有的牙齿中的牙根,其中所述含细胞的基质材料含有选自牙周韧带衍生的细胞,骨髓来源的细胞,来自牙囊的细胞中的至少一种细胞 牙髓源细胞和来自乳头乳头的细胞,培养基含有人子宫颈鳞状细胞癌细胞系的无血清培养细胞系的条件培养基中所含的成分, 含有选自IL-1和bgr,IL-6,IL-8,IL-9,EGF,IGF-1,GH,PDGF-AB,VEGF,LIF,HGF,FGF-2,FGF-1中的至少一种的添加剂 ,BMP-2,BMP-4,M-CSF,地塞米松,胰岛素,甲状腺素,降钙素原,抗坏血酸和甘油磷酸酯; 或者他们两个。

    Formation of foamed resin article
    8.
    发明授权
    Formation of foamed resin article 有权
    泡沫树脂制品的形成

    公开(公告)号:US08066253B2

    公开(公告)日:2011-11-29

    申请号:US11144018

    申请日:2005-06-03

    CPC classification number: B29C33/14 B29C44/1271 Y10T24/45958 Y10T24/4599

    Abstract: An embedment member of a foamed resin article such as a seat pad formed in a mold. The mold is provided with engaging projections and a pocket portion formed in or on an inner surface of a core thereof. A surface of the embedment member is positioned to face the core and the surface is superposed onto the surface of the core such that the projections enter into large opening portions. Then, the embedment member is slid in such a manner as to introduce the projections into narrow portions and wide portions, thereby retaining the embedment member to the core. In this state, an end portion of the embedment member is fitted into the pocket portion. To release the foamed resin article from the mold, the foamed resin article is slid in a direction opposite to the direction of the aforementioned sliding.

    Abstract translation: 泡沫树脂制品的嵌入构件,例如形成在模具中的座垫。 模具设置有接合突起和形成在其芯的内表面中或其内表面上的袋状部分。 嵌入构件的表面被定位成面对芯,并且表面被叠置在芯的表面上,使得突起进入大的开口部分。 然后,嵌入构件以将凸起引入狭窄部分和宽部分的方式滑动,从而将嵌入构件保持在芯部上。 在这种状态下,嵌入部件的端部嵌入袋部。 为了从模具中释放发泡树脂制品,发泡树脂制品沿与上述滑动方向相反的方向滑动。

    Method of discriminating particle aggregation pattern
    10.
    发明授权
    Method of discriminating particle aggregation pattern 失效
    鉴别粒子聚集图案的方法

    公开(公告)号:US5265169A

    公开(公告)日:1993-11-23

    申请号:US775809

    申请日:1991-10-11

    Abstract: A method for identifying the presence or absence of an aggregation of particles distributed on a translucent surface includes the steps of providing a light sensing device for sensing light incident thereon and producing an output value which represents the intensity of the incident light, and identifying a first output value which is produced by the light sensing device when there is no light incident thereon. The method also identifies a second output value which is produced by the light sensing means when, with no particles present on the translucent surface, light is directed through the translucent surface onto the light sensing device. With a distribution of particles deposited on the translucent surface, light is directed through the translucent surface and onto the light sensing device, causing the light sensing device to produce a third output value. A final output value is then determined as a function of said first, second and third output values.

    Abstract translation: 用于识别分布在半透明表面上的颗粒的聚集的存在或不存在的方法包括以下步骤:提供用于感测入射在其上的光的光感测装置,并产生表示入射光强度的输出值,并且识别第一 当没有光入射时由光检测装置产生的输出值。 该方法还识别由光感测装置产生的第二输出值,当在半透明表面上没有颗粒存在时,光被引导通过透光表面到光感测装置上。 随着沉积在半透明表面上的颗粒的分布,光被引导通过半透明表面并且到达光感测装置,使光感测装置产生第三输出值。 然后确定最终输出值作为所述第一,第二和第三输出值的函数。

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