利索-全球专利检索

  1. 登录
  2. 注册

搜索结果

42 条记录 (耗时 0.041 秒)

    Nucleotide primer set and nucleotide probe for detecting genotype of N-acetyltransferase-2 (NAT2)
    5.
    发明授权
    Nucleotide primer set and nucleotide probe for detecting genotype of N-acetyltransferase-2 (NAT2) 失效
    用于检测N-乙酰转移酶-2（NAT2）基因型的核苷酸引物组和核苷酸探针

    公开(公告)号：US07919611B2

    公开(公告)日：2011-04-05

    申请号：US12014592

    申请日：2008-01-15

    申请人： Naoko Nakamura ,  Keiko Ito ,  Koji Hashimoto ,  Nobuhiro Gemma

    发明人： Naoko Nakamura ,  Keiko Ito ,  Koji Hashimoto ,  Nobuhiro Gemma

    IPC分类号： C07H21/04 ,  C12Q1/68 ,  C12P19/34

    CPC分类号： C12Q1/6883 ,  C12Q2600/156

    摘要： There is provided a nucleotide primer set for LAMP amplification, used for detecting genotypes of single-nucleotide polymorphisms G590A, G857A and T341C of a NAT2 gene. There is also provided a nucleotide probe for detection of an amplification product amplified with the primer set according to the present invention. There is also provided a method of detecting the genotypes of NAT2 gene single-nucleotide polymorphisms G590A, G857A and T341C by using the primer set according to the present invention.

    摘要翻译： 提供了LAMP扩增的核苷酸引物组，用于检测NAT2基因的单核苷酸多态性G590A，G857A和T341C的基因型。 还提供了用于检测根据本发明的引物组扩增的扩增产物的核苷酸探针。 还提供了通过使用本发明的引物组来检测NAT2基因单核苷酸多态性G590A，G857A和T341C的基因型的方法。

    NUCLEOTIDE PRIMER SET AND NUCLEOTIDE PROBE FOR DETECTING GENOTYPE OF N-ACETYLTRANSFERASE-2 (NAT2)
    6.
    发明申请
    NUCLEOTIDE PRIMER SET AND NUCLEOTIDE PROBE FOR DETECTING GENOTYPE OF N-ACETYLTRANSFERASE-2 (NAT2) 失效
    用于检测N-乙酰基转移酶-2（NAT2）基因组的核酸酶基因组和核酸探针

    公开(公告)号：US20100003671A1

    公开(公告)日：2010-01-07

    申请号：US12014592

    申请日：2008-01-15

    申请人： Naoko Nakamura ,  Keiko Ito ,  Koji Hashimoto ,  Nobuhiro Gemma

    发明人： Naoko Nakamura ,  Keiko Ito ,  Koji Hashimoto ,  Nobuhiro Gemma

    IPC分类号： C12Q1/68 ,  C07H21/00

    CPC分类号： C12Q1/6883 ,  C12Q2600/156

    摘要： There is provided a nucleotide primer set for LAMP amplification, used for detecting genotypes of single-nucleotide polymorphisms G590A, G857A and T341C of a NAT2 gene. There is also provided a nucleotide probe for detection of an amplification product amplified with the primer set according to the present invention. There is also provided a method of detecting the genotypes of NAT2 gene single-nucleotide polymorphisms G590A, G857A and T341C by using the primer set according to the present invention.

    摘要翻译： 提供了LAMP扩增的核苷酸引物组，用于检测NAT2基因的单核苷酸多态性G590A，G857A和T341C的基因型。 还提供了用于检测根据本发明的引物组扩增的扩增产物的核苷酸探针。 还提供了通过使用本发明的引物组来检测NAT2基因单核苷酸多态性G590A，G857A和T341C的基因型的方法。

    NUCLEIC ACID DETECTION DEVICE
    8.
    发明申请
    NUCLEIC ACID DETECTION DEVICE 审中-公开
    核酸检测装置

    公开(公告)号：US20080233634A1

    公开(公告)日：2008-09-25

    申请号：US12048690

    申请日：2008-03-14

    申请人： Jun OKADA ,  Sadato Hongo ,  Keiko Ito ,  Kenji Ooki ,  Nobuhiro Gemma

    发明人： Jun OKADA ,  Sadato Hongo ,  Keiko Ito ,  Kenji Ooki ,  Nobuhiro Gemma

    IPC分类号： C12M1/00

    CPC分类号： G01N35/085

    摘要： A nucleic acid detection device is provided with a closed channel formed of a first channel portion, through which a washing reagent storage section for storing a washing reagent for washing a detection section for nucleic acid detection communicates with the detection section, and a second channel portion through which a pretreatment section for nucleic acid treatment communicates with the detection section. The closed channel is connected with a gas inlet/outlet path for communication with the outside. The gas inlet/outlet path is blocked by a sealing mechanism before nucleic acid detection. In storing a pretreatment reagent and the washing reagent frozen, the gas inlet/outlet path is kept open and connected to the channel. Thus, there is provided a nucleic acid detection device having a structure for preventing leakage of nucleic acid samples to the outside and which can be stored for a long period of time with the reagents therein.

    摘要翻译： 核酸检测装置设置有由第一通道部分形成的封闭通道，用于存储用于清洗用于核酸检测的检测部分的洗涤剂的洗涤剂存储部分与检测部分通信，第二通道部分 用于核酸处理的预处理部分与检测部分通信。 封闭通道与用于与外部连通的气体入口/出口路径连接。 在核酸检测之前，气体入口/出口路径被密封机构堵塞。 在储存预处理试剂和洗涤剂冻结时，气体入口/出口路径保持打开并连接到通道。 因此，提供了一种核酸检测装置，其具有防止核酸样品向外部泄漏的结构，并且可以用其中的试剂长时间储存​​。

    SAMPLE ANALYSIS METHOD AND ASSAY KIT USED THEREIN
    10.
    发明申请
    SAMPLE ANALYSIS METHOD AND ASSAY KIT USED THEREIN 失效
    样品分析方法和使用的试剂盒

    公开(公告)号：US20120171673A1

    公开(公告)日：2012-07-05

    申请号：US13340572

    申请日：2011-12-29

    申请人： Naoko NAKAMURA ,  Koji Hashimoto ,  Nobuhiro Gemma

    发明人： Naoko NAKAMURA ,  Koji Hashimoto ,  Nobuhiro Gemma

    IPC分类号： C12Q1/68

    CPC分类号： C12Q1/6837 ,  C12Q1/6809 ,  C12Q1/6853 ,  C12Q2525/161 ,  C12Q2525/301 ,  C12Q2537/143 ,  C12Q2563/179 ,  C12Q2565/514

    摘要： One embodiment is related to a method of analyzing plural samples. The method includes amplifying a plurality of samples using a first primer and second primer, wherein the first primer includes a tag sequence having a sequence different from a sample to one another and wherein a second primer used in pair with the first primer in independent reaction systems for the respective samples to obtain an amplified product in which the tag sequence is introduced, mixing amplified products obtained in the plurality of reaction systems, making the mixed amplified product react with a nucleic acid probe immobilized on a substrate, and detecting the amount of hybridization that has occurred.

    摘要翻译： 一个实施例涉及分析多个样本的方法。 该方法包括使用第一引物和第二引物扩增多个样品，其中第一引物包含具有不同于样品的序列的标签序列，并且其中与独立反应体系中的第一引物成对配对的第二引物 对于各样品获得其中引入标签序列的扩增产物，混合在多个反应体系中获得的扩增产物，使得混合的扩增产物与固定在底物上的核酸探针反应，并检测杂交的量 已经发生了。