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公开(公告)号：US10449366B2
公开(公告)日：2019-10-22
申请号：US15280339
申请日：2016-09-29
Applicant: Medtronic, Inc.
Inventor： Vincent E Splett , Todd J Sheldon , Yong K Cho , Wade M Demmer , Mark K Erickson
Abstract: An intracardiac ventricular pacemaker having a motion sensor is configured to produce a motion signal including an atrial systolic event and a ventricular diastolic event indicating a passive ventricular filling phase, set a detection threshold to a first amplitude during an expected time interval of the ventricular diastolic event and to a second amplitude lower than the first amplitude after an expected time interval of the ventricular diastolic event. The pacemaker is configured to detect the atrial systolic event in response to the motion signal crossing the detection threshold and set an atrioventricular pacing interval in response to detecting the atrial systolic event.
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公开(公告)号：US10328270B2
公开(公告)日：2019-06-25
申请号：US15377717
申请日：2016-12-13
Applicant: Medtronic, Inc.
Inventor： Wade M Demmer , Yong K Cho , Mark K Erickson , Todd J Sheldon
Abstract: An intracardiac pacemaker system is configured to produce physiological atrial event signals by a sensing circuit of a ventricular intracardiac pacemaker and select a first atrial event input as the physiological atrial event signals. The ventricular intracardiac pacemaker detects atrial events from the selected first atrial event input, determines if input switching criteria are met, and switches from the first atrial event input to a second atrial event input in response to the input switching criteria being met. The second atrial event input includes broadcast atrial event signals produced by a second implantable medical device and received by the ventricular intracardiac pacemaker.
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公开(公告)号：US09808628B2
公开(公告)日：2017-11-07
申请号：US15350708
申请日：2016-11-14
Applicant: Medtronic, Inc.
Inventor： Todd J Sheldon , Wade M Demmer
CPC classification number: A61N1/36592 , A61N1/3688 , A61N1/3756
Abstract: In some examples, a leadless pacing device (hereinafter, “LPD”) is configured for implantation in a ventricle of a heart of a patient, and is configured to switch between an atrio-ventricular synchronous pacing mode and an asynchronous ventricular pacing mode in response to detection of one or more sensing events, which may be, for example, undersensing events. In some examples, an LPD is configured to switch from a sensing without pacing mode to an atrio-ventricular synchronous pacing mode in response to determining, for a threshold number of cardiac cycles, a ventricular depolarization was not detected within a ventricular event detection window that begins at an atrial activation event.
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公开(公告)号：US09492668B2
公开(公告)日：2016-11-15
申请号：US14538518
申请日：2014-11-11
Applicant: Medtronic, Inc.
Inventor： Todd J Sheldon , Wade M Demmer
CPC classification number: A61N1/36592 , A61N1/3688 , A61N1/3756
Abstract: In some examples, a leadless pacing device (hereinafter, “LPD”) is configured for implantation in a ventricle of a heart of a patient, and is configured to switch between an atrio-ventricular synchronous pacing mode and an asynchronous ventricular pacing mode in response to detection of one or more sensing events, which may be, for example, undersensing events. In some examples, an LPD is configured to switch from a sensing without pacing mode to an atrio-ventricular synchronous pacing mode in response to determining, for a threshold number of cardiac cycles, a ventricular depolarization was not detected within a ventricular event detection window that begins at an atrial activation event.
Abstract translation: 在一些示例中，无引线起搏装置（以下称为“LPD”）被配置用于植入患者心脏的心室中，并且被配置为响应于心房间同步起搏模式和异步心室起搏模式之间的切换 以检测一个或多个感测事件，其可以是例如不足感的事件。 在一些示例中，响应于确定对于阈值数量的心动周期，在心室事件检测窗口内未检测到心室去极化，LPD被配置为从不具有起搏模式的感测切换到心室同步起搏模式 从心房激活事件开始。
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公开(公告)号：US09452292B2
公开(公告)日：2016-09-27
申请号：US14261776
申请日：2014-04-25
Applicant: Medtronic, Inc.
Inventor： Wade M Demmer , Douglas A Peterson
CPC classification number: A61N1/3702 , A61B5/04525 , A61B2017/00203 , A61N1/3622 , A61N1/3624 , A61N1/365 , A61N1/371 , A61N1/3712 , A61N1/3756
Abstract: A method and apparatus for determining stability of a patient's intrinsic rhythm in a cardiac pacing device. Cardiac pacing pulses are delivering to a chamber of a patient's heart by the pacing device at a first pulse amplitude. The device measures a first series of intervals between successive sensed and paced events. The device then determines whether the first measured series of intervals meets a stability criterion. Responsive to the first measured series of intervals failing to meet the stability criterion, the device determines whether the first measured series of intervals includes an interval between a delivered pacing pulse and a sensed event that is less than a defined duration. Responsive to the interval between a delivered pacing pulse and a sensed event being less than the defined duration, the device delivers cardiac pacing pulses to the chamber of a patient's heart at a second pulse amplitude and measures a second series of intervals between successive sensed and paced events and determines whether the second measured series of intervals meets the stability criterion.
Abstract translation: 一种用于确定心脏起搏装置中患者内在节律的稳定性的方法和装置。 心脏起搏脉冲通过起搏装置以第一脉冲幅度递送到患者心脏的室。 该装置测量连续感测和起搏事件之间的第一系列间隔。 然后，设备确定第一测量的间隔序列是否满足稳定性标准。 响应于不能满足稳定性标准的第一测量系列的间隔，该装置确定第一测量的间隔序列是否包括传递的起搏脉冲和小于所定义持续时间的感测事件之间的间隔。 响应于所输送的起搏脉冲和感测到的事件之间的间隔小于所定义的持续时间，该装置以第二脉冲幅度将心脏起搏脉冲递送到患者心脏的腔室，并且测量连续感测和起搏之间的第二系列间隔 并确定第二个测量的间隔序列是否满足稳定性标准。
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Patent Agency Ranking
6.发明申请METHODS FOR SETTING CARDIAC PACING PARAMETERS IN RELATIVELY HIGH EFFICIENCY PACING SYSTEMS 有权在相对高效率的PACING系统中设置心脏参数的方法公开(公告)号：US20140121722A1
公开(公告)日：2014-05-01
申请号：US14149277
申请日：2014-01-07
Applicant: Medtronic, Inc.
Inventor： Todd J Sheldon , Wade M Demmer
IPC: A61N1/37
CPC classification number: A61N1/3712 , A61N1/3708 , A61N1/37205 , A61N1/3756
Abstract: According to some methods, for example, preprogrammed in a microprocessor element of an implantable cardiac pacing system, at least one of a number of periodic pacing threshold searches includes steps to reduce an evoked response amplitude threshold for evoked response signal detection. The reduction may be to a minimum value measurable above zero, for example, as determined by establishing a ‘noise floor’. Alternately, amplitudes of test pacing pulses and corresponding post pulse signals are collected and reviewed to search for a break, to determine a lower value to which the evoked response threshold may be adjusted without detecting noise. Subsequent to reducing the threshold, if no evoked response signal is detected for a test pulse applied at or above a predetermined maximum desirable pulse energy, an operational pacing pulse energy is set to greater than or equal to the maximum desirable in conjunction with a reduction in pacing rate.
Abstract translation: 根据一些方法，例如，在可植入心脏起搏系统的微处理器元件中预编程，多个周期性起搏阈值搜索中的至少一个包括减少诱发响应信号检测的诱发响应振幅阈值的步骤。 该减小可以是在零以上可测量的最小值，例如通过建立“本底噪声”确定的最小值。 或者，收集和检查测试起搏脉冲和对应的后脉冲信号的振幅以搜索中断，以确定可以在不检测噪声的情况下调整诱发响应阈值的较低值。 在降低阈值之后，如果对于在预定的最大期望脉冲能量之上或之上施加的测试脉冲没有检测到诱发响应信号，则可以将运行起搏脉冲能量设置为大于或等于期望的最大值， 起搏率
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公开(公告)号：US10052494B2
公开(公告)日：2018-08-21
申请号：US14657001
申请日：2015-03-13
Applicant: Medtronic, Inc.
Inventor： Todd J Sheldon , Wade M Demmer , Teresa A Whitman
CPC classification number: A61N1/3962 , A61B5/0464 , A61B5/686 , A61B5/6869 , A61N1/3621 , A61N1/36542 , A61N1/36578 , A61N1/36585
Abstract: An implantable medical device system includes a pacemaker and an implantable cardioverter defibrillator (ICD). The pacemaker is configured to confirm a hemodynamically unstable rhythm based on an activity metric determined from an activity sensor signal after detecting a ventricular tachyarrhythmia and withhold anti-tachycardia pacing (ATP) pulses in response to confirming the hemodynamically unstable rhythm. The pacemaker may deliver ATP when a hemodynamically unstable rhythm is not confirmed based on the activity metric. The ICD is configured to detect the ATP and withhold a shock therapy in response to detecting the ATP in some examples.
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公开(公告)号：US20180117337A1
公开(公告)日：2018-05-03
申请号：US15342699
申请日：2016-11-03
Applicant: Medtronic, Inc.
Inventor： Wade M Demmer , Yong K Cho , Mark K Erickson , Michael F Hess , Todd J Sheldon , Vincent E Splett
CPC classification number: A61N1/36542 , A61N1/0573 , A61N1/36578 , A61N1/3682 , A61N1/3684 , A61N1/37205 , A61N1/3756
Abstract: An intracardiac ventricular pacemaker having a motion sensor is configured to produce a motion signal including an atrial systolic event and at least one ventricular diastolic event. The pacemaker is configured to set an atrial refractory period, detect a change in a ventricular diastolic event metric and adjust the atrial refractory period in response to detecting the change. The pacemaker sets set an atrioventricular pacing interval in response to detecting the atrial systolic event from the motion signal after expiration of the atrial refractory period.
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公开(公告)号：US20180085588A1
公开(公告)日：2018-03-29
申请号：US15280339
申请日：2016-09-29
Applicant: Medtronic, Inc.
Inventor： Vincent E Splett , Todd J Sheldon , Yong K Cho , Wade M Demmer , Mark K Erickson
CPC classification number: A61N1/36578 , A61N1/3682 , A61N1/3684 , A61N1/37205 , A61N1/3756
Abstract: An intracardiac ventricular pacemaker having a motion sensor is configured to produce a motion signal including an atrial systolic event and a ventricular diastolic event indicating a passive ventricular filling phase, set a detection threshold to a first amplitude during an expected time interval of the ventricular diastolic event and to a second amplitude lower than the first amplitude after an expected time interval of the ventricular diastolic event. The pacemaker is configured to detect the atrial systolic event in response to the motion signal crossing the detection threshold and set an atrioventricular pacing interval in response to detecting the atrial systolic event.
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公开(公告)号：US09808618B2
公开(公告)日：2017-11-07
申请号：US14694775
申请日：2015-04-23
Applicant: Medtronic, Inc.
Inventor： Wade M Demmer
CPC classification number: A61N1/059 , A61N1/362 , A61N1/36592 , A61N1/37205 , A61N1/37217 , A61N1/37264 , A61N1/3756 , A61N2001/37294
Abstract: An implantable pacemaker has a first housing and a second housing tethered to the first housing by an elongated electrical conductor. The elongated electrical conductor has a proximal end coupled to the first housing and a distal end coupled to the second housing and includes a signal line configured to carry an electrical signal between the first housing and the second housing.
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