System and method to simulate hemodynamics

    公开(公告)号:US20060223047A1

    公开(公告)日:2006-10-05

    申请号:US11440152

    申请日:2006-05-25

    IPC分类号: A01N1/02 C12M1/36 C12M3/00

    摘要: A system for hemodynamic simulation comprises a vessel having properties of a blood vessel, a reservoir containing a quantity of fluid, tubing connecting the vessel and reservoir, and at least one pump for circulating the fluid within the system. Fluid can be tissue culture medium or blood analog fluid, and the vessel may include mammalian cells attached to its inside. A drive system, comprising two reciprocating drive shafts that are coupled by a cam, enables the uncoupling of pulsatile flow and pulsatile pressure to provide independent control over wall shear stress and circumferential strain. The shaft drives two pumps that are 180 degrees out-of-phase and are connected upstream and downstream of the vessel, and effect this uncoupling.

    System and method to simulate hemodynamics
    2.
    发明申请

    公开(公告)号:US20060223048A1

    公开(公告)日:2006-10-05

    申请号:US11440155

    申请日:2006-05-25

    IPC分类号: A01N1/02 C12M1/36 C12M3/00

    摘要: A system for hemodynamic simulation comprises a vessel having properties of a blood vessel, a reservoir containing a quantity of fluid, tubing connecting the vessel and reservoir, and at least one pump for circulating the fluid within the system. Fluid can be tissue culture medium or blood analog fluid, and the vessel may include mammalian cells attached to its inside. A drive system, comprising two reciprocating drive shafts that are coupled by a cam, enables the uncoupling of pulsatile flow and pulsatile pressure to provide independent control over wall shear stress and circumferential strain. The shaft drives two pumps that are 180 degrees out-of-phase and are connected upstream and downstream of the vessel, and effect this uncoupling.

    System and method to simulate hemodynamics
    3.
    发明申请

    公开(公告)号:US20060210959A1

    公开(公告)日:2006-09-21

    申请号:US11440148

    申请日:2006-05-25

    IPC分类号: A01N1/02 C12M3/00 C12M1/36

    摘要: A system for hemodynamic simulation comprises a vessel having properties of a blood vessel, a reservoir containing a quantity of fluid, tubing connecting the vessel and reservoir, and at least one pump for circulating the fluid within the system. Fluid can be tissue culture medium or blood analog fluid, and the vessel may include mammalian cells attached to its inside. A drive system, comprising two reciprocating drive shafts that are coupled by a cam, enables the uncoupling of pulsatile flow and pulsatile pressure to provide independent control over wall shear stress and circumferential strain. The shaft drives two pumps that are 180 degrees out-of-phase and are connected upstream and downstream of the vessel, and effect this uncoupling.

    System and method to simulate hemodynamics
    4.
    发明申请

    公开(公告)号:US20060223049A1

    公开(公告)日:2006-10-05

    申请号:US11440156

    申请日:2006-05-25

    IPC分类号: A01N1/02 C12M1/36 C12M3/00

    摘要: A system for hemodynamic simulation comprises a vessel having properties of a blood vessel, a reservoir containing a quantity of fluid, tubing connecting the vessel and reservoir, and at least one pump for circulating the fluid within the system. Fluid can be tissue culture medium or blood analog fluid, and the vessel may include mammalian cells attached to its inside. A drive system, comprising two reciprocating drive shafts that are coupled by a cam, enables the uncoupling of pulsatile flow and pulsatile pressure to provide independent control over wall shear stress and circumferential strain. The shaft drives two pumps that are 180 degrees out-of-phase and are connected upstream and downstream of the vessel, and effect this uncoupling.

    System and method to simulate hemodynamics
    5.
    发明申请

    公开(公告)号:US20060223046A1

    公开(公告)日:2006-10-05

    申请号:US11440091

    申请日:2006-05-25

    IPC分类号: A01N1/02 C12M3/00 C12M1/36

    摘要: A system for hemodynamic simulation comprises a vessel having properties of a blood vessel, a reservoir containing a quantity of fluid, tubing connecting the vessel and reservoir, and at least one pump for circulating the fluid within the system. Fluid can be tissue culture medium or blood analog fluid, and the vessel may include mammalian cells attached to its inside. A drive system, comprising two reciprocating drive shafts that are coupled by a cam, enables the uncoupling of pulsatile flow and pulsatile pressure to provide independent control over wall shear stress and circumferential strain. The shaft drives two pumps that are 180 degrees out-of-phase and are connected upstream and downstream of the vessel, and effect this uncoupling.