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公开(公告)号：US20090219512A1
公开(公告)日：2009-09-03
申请号：US12094475
申请日：2006-11-27
Applicant: Michael L. Myrick , Robert P. Freese , Luisa Profeta , Jonathan H. James , John C. Blackburn , Ryan J. Priore
Inventor： Michael L. Myrick , Robert P. Freese , Luisa Profeta , Jonathan H. James , John C. Blackburn , Ryan J. Priore
IPC: G01J3/00
CPC classification number: G01J3/02 , G01J3/0205 , G01J3/021 , G01J3/0232 , G01J3/0291 , G01J3/08 , G01J3/28 , G01J3/36 , G01N21/274 , G01N21/35 , G01N21/3504 , G01N21/3563 , G01N21/3577
Abstract: A method of selecting components for a multivariate optical computing and analysis system to isolate a spectral region includes selecting a spectral region of interest; selecting a spectral element with a predetermined transmission characteristic to control a spectral range of an illumination source; illuminating a sample with the illumination source; and analyzing an optical frequency returned by the sample relative to the spectral region of interest.
Abstract translation: 选择用于多变量光学计算和分析系统以分离光谱区域的组件的方法包括选择感兴趣的光谱区域; 选择具有预定传输特性的频谱元件以控制照明源的光谱范围; 用照明源照射样品; 以及分析由样本相对于感兴趣的光谱区返回的光频率。
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公开(公告)号：US08352205B2
公开(公告)日：2013-01-08
申请号：US12528101
申请日：2008-02-25
Applicant: Michael L. Myrick , Luisa Profeta
Inventor： Michael L. Myrick , Luisa Profeta
CPC classification number: G01J3/28 , G01J3/02 , G01J3/0232 , G01J3/12 , G01N21/274 , G01N21/31 , G01N2201/12769
Abstract: The present subject matter is direct to methodologies for calibrating data obtained from an optical analysis system. An initial calibration matrix of sampled analyte concentrations is modified using mean-centering techniques and selection of low and high analyte concentration spectra to produce a two-point calibration. A modified calibration matrix is produced by generating a non-linear calibration matrix by multiplying the initial calibration matrix by the two-point calibration. In an alternate embodiment, an initial multivariate optical element design is modified by iteratively adjusting the design based on standard error of calibration determination based on non-linerly fitted functions.
Abstract translation: 本主题直接涉及用于校准从光学分析系统获得的数据的方法。 使用平均定心技术和低分辨率和高分析物浓度光谱的选择来修改采样分析物浓度的初始校准矩阵，以产生两点校准。 通过将初始校准矩阵乘以两点校准来生成非线性校准矩阵来产生修改的校准矩阵。 在替代实施例中，通过基于非线性拟合函数的校准确定的标准误差迭代地调整设计来修改初始多变量光学元件设计。
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公开(公告)号：US20100153048A1
公开(公告)日：2010-06-17
申请号：US12528101
申请日：2008-02-25
Applicant: Michael L. Myrick , Luisa Profeta
Inventor： Michael L. Myrick , Luisa Profeta
IPC: G06F19/00
CPC classification number: G01J3/28 , G01J3/02 , G01J3/0232 , G01J3/12 , G01N21/274 , G01N21/31 , G01N2201/12769
Abstract: The present subject matter is direct to methodologies for calibrating data obtained from an optical analysis system. An initial calibration matrix of sampled analyte concentrations is modified using mean-centering techniques and selection of low and high analyte concentration spectra to produce a two-point calibration. A modified calibration matrix is produced by generating a non-linear calibration matrix by multiplying the initial calibration matrix by the two-point calibration. In an alternate embodiment, an initial multivariate optical element design is modified by iteratively adjusting the design based on standard error of calibration determination based on non-linerly fitted functions.
Abstract translation: 本主题直接涉及用于校准从光学分析系统获得的数据的方法。 使用平均定心技术和低分辨率和高分析物浓度光谱的选择来修改采样分析物浓度的初始校准矩阵，以产生两点校准。 通过将初始校准矩阵乘以两点校准来生成非线性校准矩阵来产生修改的校准矩阵。 在替代实施例中，通过基于非线性拟合函数的校准确定的标准误差迭代地调整设计来修改初始多变量光学元件设计。
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